Genomes and Genes
Edward A Felinski
Affiliation: Pennsylvania State University
- Glucocorticoid regulation of endothelial cell tight junction gene expression: novel treatments for diabetic retinopathyEdward A Felinski
Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA
Curr Eye Res 30:949-57. 2005....
- Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeabilityTomoaki Murakami
Department of Cellular and Molecular Physiology and Ophthalmology, Penn State College of Medicine, Hershey, Pennsylvania 17033, USA
J Biol Chem 284:21036-46. 2009..These data demonstrate a novel mechanism of VEGF-induced occludin phosphorylation and ubiquitination that contributes to TJ trafficking and subsequent vascular permeability...
- Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-elementEdward A Felinski
Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
Exp Eye Res 86:867-78. 2008..These data suggest a novel mechanism for glucocorticoid induction of vascular endothelial barrier properties through increased occludin and claudin-5 gene expression...
- VEGF activation of protein kinase C stimulates occludin phosphorylation and contributes to endothelial permeabilityNicole S Harhaj
Departments of Cellular and Molecular Physiology, Penn State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA
Invest Ophthalmol Vis Sci 47:5106-15. 2006..Regulation of PKC activity and tight junction protein modifications may have therapeutic implications for treatment of diabetic retinopathy and brain tumors...