Timothy J Craig

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. doi request reprint The role of montelukast on perennial allergic rhinitis and associated sleep disturbances and daytime somnolence
    Carah B Santos
    Penn State College of Medicine, Hershey, PA 17033, USA
    Allergy Asthma Proc 29:140-5. 2008
  2. pmc 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema
    Tom Bowen
    Departments of Medicine and Paediatrics, University of Calgary, Calgary, Alberta, Canada
    Allergy Asthma Clin Immunol 6:24. 2010
  3. doi request reprint Asthma Clinical Research Network: lessons learned
    Timothy Craig
    Penn State University, Hershey, PA, USA
    Mt Sinai J Med 78:671-82. 2011
  4. doi request reprint Aeroallergen sensitization correlates with PC(20) and exhaled nitric oxide in subjects with mild-to-moderate asthma
    Timothy J Craig
    Division of Pulmonary Care, Pennsylvania State University College of Medicine, Hershey, PA 17033 0853, USA
    J Allergy Clin Immunol 121:671-7. 2008
  5. doi request reprint Appraisal of danazol prophylaxis for hereditary angioedema
    Timothy J Craig
    Allergy Asthma and Immunology Section, Division of Pulmonary, Allergy, and Critical Care, Penn State University, Hershey, Pennsylvania, USA
    Allergy Asthma Proc 29:225-31. 2008
  6. doi request reprint Sleep impairment in allergic rhinitis, rhinosinusitis, and nasal polyposis
    Timothy J Craig
    Pennsylvania State University College of Medicine, Hershey, PA 17033 0850, USA
    Am J Otolaryngol 29:209-17. 2008
  7. doi request reprint When is prophylaxis for hereditary angioedema necessary?
    Timothy Craig
    Department of Medicine and Pediatrics, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania 17033, USA
    Ann Allergy Asthma Immunol 102:366-72. 2009
  8. doi request reprint Recent advances in management and treatment of hereditary angioedema
    Niti Sardana
    Department of Pediatrics, Weill Cornell Medical Center, NewYork Presbyterian Hospital, New York, NY, USA
    Pediatrics 128:1173-80. 2011
  9. doi request reprint Aeroallergen sensitization in asthma: prevalence and correlation with severity
    Timothy J Craig
    Pennsylvania State University College of Medicine, Section of Allergy, Asthma, and Immunology, Hershey, Pennsylvania 17033 0853, USA
    Allergy Asthma Proc 31:96-102. 2010
  10. doi request reprint Congestion and sleep impairment in allergic rhinitis
    Timothy J Craig
    Hershey Medical Center, Penn State University, 500 University Drive, Hershey, PA, 17033 0850, USA
    Curr Allergy Asthma Rep 10:113-21. 2010

Detail Information

Publications71

  1. doi request reprint The role of montelukast on perennial allergic rhinitis and associated sleep disturbances and daytime somnolence
    Carah B Santos
    Penn State College of Medicine, Hershey, PA 17033, USA
    Allergy Asthma Proc 29:140-5. 2008
    ..In a small cohort of subjects, montelukast, when compared with placebo, improved the symptoms of PAR and reduced the fatigue and daytime somnolence associated with the disorder...
  2. pmc 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema
    Tom Bowen
    Departments of Medicine and Paediatrics, University of Calgary, Calgary, Alberta, Canada
    Allergy Asthma Clin Immunol 6:24. 2010
    ....
  3. doi request reprint Asthma Clinical Research Network: lessons learned
    Timothy Craig
    Penn State University, Hershey, PA, USA
    Mt Sinai J Med 78:671-82. 2011
    ....
  4. doi request reprint Aeroallergen sensitization correlates with PC(20) and exhaled nitric oxide in subjects with mild-to-moderate asthma
    Timothy J Craig
    Division of Pulmonary Care, Pennsylvania State University College of Medicine, Hershey, PA 17033 0853, USA
    J Allergy Clin Immunol 121:671-7. 2008
    ..Aeroallergen sensitization in adult asthmatic patients from a wide geographic area has not been correlated with patients' characteristics, markers of airways inflammation, and lung function...
  5. doi request reprint Appraisal of danazol prophylaxis for hereditary angioedema
    Timothy J Craig
    Allergy Asthma and Immunology Section, Division of Pulmonary, Allergy, and Critical Care, Penn State University, Hershey, Pennsylvania, USA
    Allergy Asthma Proc 29:225-31. 2008
    ....
  6. doi request reprint Sleep impairment in allergic rhinitis, rhinosinusitis, and nasal polyposis
    Timothy J Craig
    Pennsylvania State University College of Medicine, Hershey, PA 17033 0850, USA
    Am J Otolaryngol 29:209-17. 2008
    ..Such trials will help to identify the most effective therapies for sleep impairment in these 3 nasal conditions...
  7. doi request reprint When is prophylaxis for hereditary angioedema necessary?
    Timothy Craig
    Department of Medicine and Pediatrics, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania 17033, USA
    Ann Allergy Asthma Immunol 102:366-72. 2009
    ..To determine when newer agents, such as C1 esterase inhibitor protein (C1-INH), should be considered as prophylaxis to decrease hereditary angioedema (HAE) attacks as an alternative to androgens, which have significant adverse events...
  8. doi request reprint Recent advances in management and treatment of hereditary angioedema
    Niti Sardana
    Department of Pediatrics, Weill Cornell Medical Center, NewYork Presbyterian Hospital, New York, NY, USA
    Pediatrics 128:1173-80. 2011
    ..Morbidity and mortality are significant, and new and pending therapies are now available to reduce the risk associated with the disease...
  9. doi request reprint Aeroallergen sensitization in asthma: prevalence and correlation with severity
    Timothy J Craig
    Pennsylvania State University College of Medicine, Section of Allergy, Asthma, and Immunology, Hershey, Pennsylvania 17033 0853, USA
    Allergy Asthma Proc 31:96-102. 2010
    ..Higher levels of IgE and eNO and lower values of PC(20), are noted in patients with asthma and aeroallergen sensitization...
  10. doi request reprint Congestion and sleep impairment in allergic rhinitis
    Timothy J Craig
    Hershey Medical Center, Penn State University, 500 University Drive, Hershey, PA, 17033 0850, USA
    Curr Allergy Asthma Rep 10:113-21. 2010
    ..It explores the adverse effects of disturbed sleep on quality of life and how these conditions can be reduced by therapies that decrease congestion...
  11. pmc Treatment of Hereditary Angioedema: items that need to be addressed in practice parameter
    Callie Dagen
    Section of Allergy Asthma and Immunology, Medicine and Pediatrics, Penn State University, 500 University Drive, Hershey, PA 17033, USA
    Allergy Asthma Clin Immunol 6:11. 2010
    ..Treatment of HAE in many parts of the world fall short and certain items need to be addressed in future guidelines...
  12. ncbi request reprint Allergic rhinitis remains an important disease
    Timothy J Craig
    Pennsylvania State University College of Medicine, Hershey, USA
    J Am Osteopath Assoc 102:S1-2. 2002
  13. doi request reprint A 64-year-old man with chronic obstructive pulmonary disease and an atypical rash
    Ethan T Craig
    Penn State College of Medicine, Penn State University, Hershey, Pennsylvania 17033, USA
    Allergy Asthma Proc 32:325-8. 2011
    ..Basic laboratory workup revealed conflicting information, leading to a diagnostic challenge discussed in this article. Ultimately, careful testing did reveal the diagnosis and the patient was treated accordingly...
  14. ncbi request reprint Chronic fatigue syndrome: evaluation and treatment
    Timothy Craig
    Department of Medicine, Pennsylvania State University College of Medicine, Hershey 17033, USA
    Am Fam Physician 65:1083-90. 2002
    ..Therefore, treatment of CFS may be variable and should be tailored to each patient. Therapy should include exercise, diet, good sleep hygiene, antidepressants, and other medications, depending on the patient's presentation...
  15. doi request reprint The safety profile of ciclesonide in the treatment of persistent asthma
    Timothy Craig
    Department of Medicine and Pediatrics, Penn State University, College of Medicine, Hershey, Pennsylvania 17033, USA
    Allergy Asthma Proc 30:315-24. 2009
    ..The favorable safety profile of CIC may allay patient and physician concern regarding ICS when using this agent. Guideline-recommended use of ICS medications may help optimize treatment outcomes in asthma...
  16. doi request reprint Per-attack reporting of prodromal symptoms concurrent with C1-inhibitor treatment of hereditary angioedema attacks
    Michael J Prematta
    Allergy, Asthma and Immunology Section, Penn State University, Hershey, Pennsylvania, USA
    Adv Ther 29:913-22. 2012
    ..This study was designed to prospectively identify prodomal characteristics in patients voluntarily reporting such information around the time of seeking treatment for an acute HAE attack...
  17. pmc Associations between air pollution and peak expiratory flow among patients with persistent asthma
    Zhengmin Qian
    Department of Public Health Sciences, Pennsylvania State University, Hershey, Pennsylvania, USA
    J Toxicol Environ Health A 72:39-46. 2009
    ..The results show that the two medication regimens protected against the effects of PM(10). However, salmeterol increased the sensitivity to NO2 and triamcinalone enhanced the sensitivity to SO2...
  18. ncbi request reprint How do topical nasal corticosteroids improve sleep and daytime somnolence in allergic rhinitis?
    Timothy J Craig
    Allergy, Asthma and Immunology Section, Penn State University, Hershey Medical Center, Hershey, PA 17033, USA
    J Allergy Clin Immunol 116:1264-6. 2005
    ..01) and daytime somnolence (P = .01). Thus, topical intranasal corticosteroids should be used to decrease nasal congestion and to improve sleep and daytime somnolence in patients manifesting these symptoms...
  19. ncbi request reprint Nasal obstruction, the airway, and the athlete
    Laura H Fisher
    Department of Asthma, Allergy, and Immunology, The Pennsylvania State University, Milton S Hershey Medical Center, Hershey, PA, USA
    Clin Rev Allergy Immunol 29:151-8. 2005
    ..Treatment of allergic rhinitis can improve sleep and foster productivity. Control of rhinitis and nasal congestion, which is obtained by various therapies, may reverse lower airway tendency to bronchoconstriction...
  20. doi request reprint Sleep impairment and daytime sleepiness in patients with allergic rhinitis: the role of congestion and inflammation
    Alison Thompson
    Penn State University, Hershey Medical Center, Hershey, Pennsylvania
    Ann Allergy Asthma Immunol 111:446-51. 2013
    ..To investigate the association of rhinitis with stress, fatigue, decrease productivity, inflammation, and sleep disordered breathing...
  21. doi request reprint Frequency, timing, and type of prodromal symptoms associated with hereditary angioedema attacks
    Michael J Prematta
    Penn State Milton S Hershey Medical Center, Section of Allergy and Immunology, Hershey, Pennsylvania 17033 0850, USA
    Allergy Asthma Proc 30:506-11. 2009
    ..This high frequency suggests that prodromal symptoms could be a reliable indication to begin treatment to prevent an acute HAE attack, thus decreasing the anxiety associated with having an HAE attack...
  22. ncbi request reprint A practical approach to allergic rhinitis and sleep disturbance management
    Michael J Davies
    Department of Medicine, Division of Pulmonary, Allergy, and Critical Care, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA
    Allergy Asthma Proc 27:224-30. 2006
    ..Montelukast significantly improves both daytime and nighttime symptoms. AR treatment should endeavor to improve daytime and nighttime symptoms, sleep, and productivity thereby improving quality of life...
  23. ncbi request reprint Allergic rhinitis and its effect on sleep, fatigue, and daytime somnolence
    Carah B Santos
    Allergy Research, Hershey Medical Center, Penn State University, Hershey, Pennsylvania 17033 0850, USA
    Ann Allergy Asthma Immunol 97:579-86; quiz 586-9, 671. 2006
    ..To examine the adverse effects of sleep impairment on the quality of life of patients with the disorder and how these effects can be treated with therapies targeted at the underlying problems that influence sleep...
  24. ncbi request reprint The importance of rhinitis on sleep, daytime somnolence, productivity and fatigue
    Lesley Woods
    Division of Pulmonary, Allergy and Critical Care, Penn State University College of Medicine, Hershey, Pennsylvania 17033, USA
    Curr Opin Pulm Med 12:390-6. 2006
    ..The release of inflammatory mediators and activation of inflammatory cells results in nasal congestion, causing disrupted sleep and subsequent daytime somnolence...
  25. doi request reprint Effect of time to treatment on response to C1 esterase inhibitor concentrate for hereditary angioedema attacks
    Timothy J Craig
    Penn State University College of Medicine, Hershey, Pennsylvania, USA
    Ann Allergy Asthma Immunol 111:211-5. 2013
    ..It is thought that treatment of an acute HAE attack with C1-INH as early as possible improves efficacy, but there are limited data from prospective studies supporting this recommendation...
  26. doi request reprint Treatment response after repeated administration of C1 esterase inhibitor for successive acute hereditary angioedema attacks
    Timothy J Craig
    Penn State University, Hershey, Pennsylvania 17033, USA
    Allergy Asthma Proc 33:354-61. 2012
    ..Treatment with 20 U/kg of C1-INH concentrate provided consistent treatment response in patients treated for multiple successive HAE attacks at any body location. (Clinicaltrials.gov identifier: NCT00292981)...
  27. doi request reprint The role of pseudoephedrine on daytime somnolence in patients suffering from perennial allergic rhinitis (PAR)
    Amir A Sherkat
    Penn State University, Hershey Medical Center, Hershey, Pennsylvania, USA
    Ann Allergy Asthma Immunol 106:97-102. 2011
    ..This inflammation of the nose leads to nasal congestion and a reduction in sleep quality, resulting in daytime somnolence...
  28. doi request reprint Adverse events associated with intranasal influenza vaccine in the United States
    Neetu Vasu
    Division of Pulmonary, Allergy and Critical Care, Penn State College of Medicine, Hershey Medical Center, Hershey, PA 17033, USA
    Ther Adv Respir Dis 2:193-8. 2008
    ..PubMed, Ovid, and Google searches were conducted. Searched articles relating to allergic reactions, asthma or food allergy, and LAIV were reviewed...
  29. ncbi request reprint Assessing outcomes from the sleep disturbance associated with rhinitis
    Ellen L Pratt
    Section of Allergy, Asthma, and Immunology, Penn State Milton S Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA
    Curr Opin Allergy Clin Immunol 7:249-56. 2007
    ....
  30. doi request reprint Response to ecallantide treatment of acute attacks of hereditary angioedema based on time to intervention: results from the EDEMA clinical trials
    Erin Banta
    Section of Allergy, Asthma, and Immunology, Penn State University, Hershey, Pennsylvania 17033, USA
    Allergy Asthma Proc 32:319-24. 2011
    ..4%). As with other therapies for HAE early ecallantide therapy is optimal. Treatment with ecallantide within 6 hours of symptom onset leads to more rapid and sustained improvement of symptoms...
  31. doi request reprint Small bowel intussusception: an unusual presentation of angioedema
    Kusum Sharma
    Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Penn State University Milton S Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA
    Allergy Asthma Proc 31:84-7. 2010
    ..The patient had a history of multiple episodes of swelling of extremities, face, and genitalia. The Allergy Consult Service was consulted for perioperative management of his angioedema...
  32. doi request reprint The perceived obstacles in performing patch test to detect allergic contact dermatitis: a comparison between community allergists and directors of allergy training programs
    Gisoo Ghaffari
    Allergy, Asthma and Immunology Clinic, Penn State College of Medicine, Milton S Hershey Medical Center, Hershey, Pennsylvania 17033 0850, USA
    Ann Allergy Asthma Immunol 100:323-6. 2008
    ..Patch testing (PT) is the gold standard test to detect allergic contact dermatitis. Despite its usefulness, it is not universally performed in allergy practices...
  33. ncbi request reprint Effects of poor sleep in allergic rhinitis
    Laura Fisher
    Department of Medicine, Allergy, Asthma and Immunology H041, Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, USA
    Curr Opin Allergy Clin Immunol 5:11-6. 2005
    ..By understanding these mechanisms and by becoming familiar with effective treatments for allergic rhinitis that are beneficial in alleviating rather than worsening daytime somnolence, physicians may improve patient quality of life...
  34. pmc Prospective study of rapid relief provided by C1 esterase inhibitor in emergency treatment of acute laryngeal attacks in hereditary angioedema
    Timothy J Craig
    Asthma and Respiratory Research, Penn State University, 500 University Drive, Hershey, PA 17033, USA
    J Clin Immunol 30:823-9. 2010
    ..We assessed the efficacy of C1-INH concentrate in the emergency treatment of rarely occurring acute laryngeal HAE attacks in a prospective, open-label clinical study...
  35. doi request reprint Is there a need for clinical guidelines in the United States for the diagnosis of hereditary angioedema and the screening of family members of affected patients?
    Michael L Lunn
    Division of Pulmonary, Allergy, and Critical Care Medicine, Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania 17033, USA
    Ann Allergy Asthma Immunol 104:211-4. 2010
    ....
  36. ncbi request reprint Asthma and the diver
    Michael J Davies
    Department of Asthma, Allergy, and Immunology, The Pennsylvania State University, Milton S Hershey Medical Center, Hershey, PA, USA
    Clin Rev Allergy Immunol 29:131-8. 2005
    ..Under the right circumstances, the patient with asthma can safely participate in recreational diving without apparent increased risk of an asthma-related event...
  37. ncbi request reprint The correlation between allergic rhinitis and sleep disturbance
    Timothy J Craig
    Allergy Section, Department of Medicine, Pennsylvania State University College of Medicine, Hershey, PA, USA
    J Allergy Clin Immunol 114:S139-45. 2004
    ..Montelukast significantly improves both daytime and nighttime symptoms. AR treatment should endeavor to improve daytime and nighttime symptoms, sleep, and productivity, thereby improving quality of life...
  38. ncbi request reprint Treatment of hereditary angioedema: current perspectives
    Svetlana I Krassilnikova
    Section of Allergy, Asthma and Immunology, Penn State University, Milton S Hershey Medical Center, Hershey, PA 17033, USA
    Recent Pat Inflamm Allergy Drug Discov 2:166-74. 2008
    ..This review article also discusses some recent patents related to the filed...
  39. doi request reprint Recent advances in the management of hereditary angioedema
    Stephen E Hemperly
    Department of Medicine, Lehigh Valley Health Network, Allentown, Pennsylvania, USA
    J Am Osteopath Assoc 113:546-55. 2013
    ..The authors review current and novel treatments for patients with HAE. ..
  40. doi request reprint ACE inhibitor-induced angioedema
    Monali Vasekar
    Department of Medicine, Penn State University, Hershey, PA 17033, USA
    Curr Allergy Asthma Rep 12:72-8. 2012
    ..In this article, we discuss the mechanism, prevalence, pathophysiology, and management of ACEiIA, with focus on newer therapies recently approved for HAE and how they may be effective for ACEiIA...
  41. doi request reprint Mometasone furoate dry powder inhaler for the treatment of asthma
    Tracy B Fausnight
    Penn State Hershey Medical Center, Penn State College of Medicine Pediatrics, Section of Allergy and Immunology, 500 University Drive, Hershey, PA 17033, USA
    Expert Opin Pharmacother 12:2707-12. 2011
    ..Mometasone furoate dry powder is an inhaled corticosteroid that is approved for once-daily treatment of asthma in both adults and children as young as 4 years...
  42. ncbi request reprint A safety review of long-acting beta2-agonists in patients with asthma
    Nicholas L Rider
    Allergy, Asthma, and Immunology Section, Penn State University Milton S Hershey Medical Center, 500 University Drive, Hershey, PA 17033 2360, USA
    J Am Osteopath Assoc 106:562-7. 2006
    ..However, when used in combination with an ICS, they decrease both rescue-medication use and symptoms, increase lung function, and act as steroid-sparing agents...
  43. ncbi request reprint Early diagnosis is key in vancomycin-induced linear IgA bullous dermatosis and Stevens-Johnson syndrome
    Douglas H Jones
    Milton S Hershey Medical Center, Pennsylvania State University, Hershey, PA 17033 0850, USA
    J Am Osteopath Assoc 104:157-63. 2004
    ..These blistering disorders can have clinical manifestations that are difficult to distinguish; however, it is important to make the distinction because treatment and prognosis are different...
  44. ncbi request reprint The effect of topical nasal fluticasone on objective sleep testing and the symptoms of rhinitis, sleep, and daytime somnolence in perennial allergic rhinitis
    Timothy J Craig
    Division of Medicine, Section of Pulmonary, Allergy, Critical Care, Pennsylvania State University, 500 University Drive, P O Box 850, Hershey, PA 17033, USA
    Allergy Asthma Proc 24:53-8. 2003
    ..However, fluticasone used at approved doses improves subjective sleep in patients with perennial allergic rhinitis without a change in the apnea/hypopnea index...
  45. doi request reprint Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks
    Timothy J Craig
    Penn State University College of Medicine, Hershey, PA, USA
    J Allergy Clin Immunol 124:801-8. 2009
    ..Hereditary angioedema caused by C1 esterase inhibitor deficiency is a rare disorder...
  46. doi request reprint A comparison of intranasal corticosteroid, leukotriene receptor antagonist, and topical antihistamine in reducing symptoms of perennial allergic rhinitis as assessed through the Rhinitis Severity Score
    Niti Sardana
    College of Medicine, Penn State University, Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA
    Allergy Asthma Proc 31:5-9. 2010
    ..Systemic medication, montelukast, as expected, provided better relief for symptoms distant from the nasal cavity, and the antihistamine, azelastine, reduced rhinorrhea, more than either montelukast or budesonide...
  47. doi request reprint High-grade fever and pancytopenia in an adult patient with common variable immune deficiency
    Puneet Bajaj
    1Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Section of Allergy and Immunology, The Pennsylvania State University Milton S Hershey Medical Center, Hershey, Pennsylvania
    Allergy Asthma Proc 35:78-82. 2014
    ..Because allergy and immunology physicians commonly treat CVID patients, they should be aware of this disease condition including pathophysiology, clinical presentation, laboratory workup, and treatment options. ..
  48. doi request reprint Variability of prodromal signs and symptoms associated with hereditary angioedema attacks: a literature review
    John G Kemp
    Department of Medicine, Section of Allergy, Asthma, and Immunology, Penn State University, College of Medicine, Hershey, Pennsylvania 17033, USA
    Allergy Asthma Proc 30:493-9. 2009
    ..There is considerable variability of the prodromal manifestations that may occur before or during HAE attacks. We have not found any evidence that their sensitivity and specificity for accurately predicting such attacks has been studied...
  49. ncbi request reprint Statistical issues in clinical trials that involve the double-blind, placebo-controlled food challenge
    Vernon M Chinchilli
    Department of Health Evaluation Sciences, Penn State College of Medicine, Hershey, PA 17033 0855, USA
    J Allergy Clin Immunol 115:592-7. 2005
    ..Statistical software packages can be adapted to perform such analyses...
  50. pmc A challenging diagnosis of alpha-1-antitrypsin deficiency: identification of a patient with a novel F/Null phenotype
    Michael R Ringenbach
    Department of Medicine, Section of Allergy and Immunology, The Pennsylvania State University Milton S, Hershey Medical Center, 500 University Dr, Hershey, PA 17033, USA
    Allergy Asthma Clin Immunol 7:18. 2011
    ....
  51. ncbi request reprint Fresh frozen plasma for the treatment of hereditary angioedema
    Michael Prematta
    Allergy, Asthma and Immunology Section, Penn State University, Hershey Medical Center, Hershey, Pennsylvania, USA
    Ann Allergy Asthma Immunol 98:383-8. 2007
    ..However, because FFP also contains other substrates, it has been hypothesized to have the potential to worsen or precipitate an acute attack of HAE...
  52. doi request reprint Liver enzyme elevation and normal pulmonary function in an adult with a declining forced expiratory volume in 1 second
    Nicholas L Rider
    Division of Allergy and Immunology, The Pennsylvania State University Milton S Hershey Medical Center, Hershey, Pennsylvania, USA
    Allergy Asthma Proc 29:345-8. 2008
    ....
  53. doi request reprint Summary of the International Multicenter Prospective Angioedema C1-inhibitor Trials 1 and 2 (IMPACT1 and 2)
    Svetlana Krassilnikova
    Allergy, Asthma and Immunology, Pennsylvania State University, Hershey, PA 17033, USA
    Expert Rev Clin Immunol 6:327-34. 2010
    ..While final data from the IMPACT2 trial are not yet released, this article reviews currently available data from previous reports and abstract presentations...
  54. ncbi request reprint Inflammatory responses in allergic rhinitis: traditional approaches and novel treatment strategies
    Sadeq A Quraishi
    Department of Medicine, Section for Pulmonary, Allergy, and Immunology, Pennsylvania State University College of Medicine, Hershey, USA
    J Am Osteopath Assoc 104:S7-15. 2004
    ..As newer strategies emerge, treatment regimens for allergic rhinitis should continue to improve not only daytime symptoms, but also nighttime symptoms and sleep with the fewest possible adverse effects...
  55. ncbi request reprint Assessment of care and disease management of patients with asthma in an overseas U.S. Army health clinic
    Cherié M Inglis
    The Milton S Hershey Medical Center, 500 University Drive, Hershey, PA 17033 2360, USA
    Mil Med 169:558-61. 2004
    ..Although our findings were encouraging, this study has highlighted that there is opportunity for improvement...
  56. pmc Treatment of hereditary angioedema with plasma-derived C1 inhibitor
    Michael J Prematta
    Section of Allergy and Immunology, Penn State University, Milton S Hershey Medical Center, PA, USA
    Ther Clin Risk Manag 4:975-82. 2008
    ..Studies are still being conducted to establish its safety and efficacy as required by the FDA...
  57. ncbi request reprint The effect of intranasal steroid budesonide on the congestion-related sleep disturbance and daytime somnolence in patients with perennial allergic rhinitis
    Faina Gurevich
    College of Medicine, Penn State University, Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA
    Allergy Asthma Proc 26:268-74. 2005
    ..01), and "refreshing and restorative" sleep (p = 0.04) in the active group. Nasal corticosteroid BUD is effective in reducing nasal congestion, daytime somnolence, and daytime fatigue, and improving sleep quality in PAR...
  58. ncbi request reprint Poor sleep and daytime somnolence in allergic rhinitis: significance of nasal congestion
    Sujani Kakumanu
    Department of Medicine, Pulmonary, Allergy, Critical Care, Hershey, Pennsylvania 17033, USA
    Am J Respir Med 1:195-200. 2002
    ..Further research involving objective measures of sleep quality is necessary to determine the efficacy of medications in the treatment of allergic rhinitis associated with fatigue and daytime somnolence...
  59. pmc Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma
    Stephen C Lazarus
    University of California, San Francisco, 505 Parnassus Avenue, M 1083, San Francisco, CA 94143 0111, USA
    Am J Respir Crit Care Med 175:783-90. 2007
    ..One-quarter to one-third of individuals with asthma smoke, which may affect response to therapy and contribute to poor asthma control...
  60. pmc Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma
    Aaron Deykin
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Respir Crit Care Med 175:228-34. 2007
    ..The elements of asthma control achieved by LABAs (improved lung function) and leukotriene receptor antagonists (LTRAs; protection against exacerbations) may be complementary as well...
  61. ncbi request reprint Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids
    Aaron Deykin
    Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    J Allergy Clin Immunol 115:720-7. 2005
    ..Although inhaled corticosteroids (ICSs) are effective in preventing deterioration in asthma control, at least half of subjects with mild-to-moderate asthma will remain stable when these agents are discontinued...
  62. pmc beta-Adrenergic receptor polymorphisms and response to salmeterol
    Michael E Wechsler
    Brigham and Women s Hospital, 75 Francis Street, Boston, MA, 02115, USA
    Am J Respir Crit Care Med 173:519-26. 2006
    ..Several studies suggest that patients with asthma who are homozygous for arginine at the 16th position of the beta2-adrenergic receptor may not benefit from short-acting beta-agonists...
  63. ncbi request reprint Daily versus as-needed corticosteroids for mild persistent asthma
    Homer A Boushey
    University of California at San Francisco, San Francisco, USA
    N Engl J Med 352:1519-28. 2005
    ....
  64. ncbi request reprint Inhaled mometasone furoate reduces oral prednisone usage and improves lung function in severe persistent asthma
    Jill P Karpel
    North Shore University Hospital, New Hyde Park, NY 11040, USA
    Respir Med 101:628-37. 2007
    ..The reduction of oral prednisone use by mometasone furoate (MF) delivered by HFA-227 metered dose inhaler (MDI) was examined in oral corticosteroid (OCS)-dependent patients with severe persistent asthma...
  65. ncbi request reprint Improved immunotherapy with a rapid allergen vaccination schedule: a study of 137 patients
    William Smits
    Allergy and Asthma Center, 7230 Engle Rd, Suite 300, Fort Wayne, IN 46804 2234, USA
    Ear Nose Throat J 82:881-7. 2003
    ..Moreover, RAV is associated with less morbidity and less expense. Our findings should encourage physicians who treat allergy patients to give further consideration to using RAV...
  66. ncbi request reprint Significant variability in response to inhaled corticosteroids for persistent asthma
    Stanley J Szefler
    National Jewish Medical and Research Center, Department of Pediatrics, Denver, CO 80206, USA
    J Allergy Clin Immunol 109:410-8. 2002
    ..A clinical model is needed to compare inhaled corticosteroids (ICSs) with respect to efficacy...
  67. ncbi request reprint Clinical and entomological factors influence the outcome of sting challenge studies
    David B K Golden
    Johns Hopkins Asthma and Allergy Center, Baltimore, MD 21224, USA
    J Allergy Clin Immunol 117:670-5. 2006
    ..The reported frequency of systemic reactions to challenge sting varies greatly...
  68. ncbi request reprint Systemic effect comparisons of six inhaled corticosteroid preparations
    Richard J Martin
    National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Am J Respir Crit Care Med 165:1377-83. 2002
    ..This study represents the first step in evaluation of ICS efficacy based on equisystemic (cortisol suppression) effects of a given ICS, rather than doses judged arbitrarily to be comparable on a microgram basis...
  69. ncbi request reprint Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial
    Elliot Israel
    Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Lancet 364:1505-12. 2004
    ..However, the existence of any genotype-dependent difference has not been tested in a prospective clinical trial...
  70. ncbi request reprint Effect of topical nasal corticosteroids on patients with chronic fatigue syndrome and rhinitis
    Sujani S Kakumanu
    Division of Biology and Medicine, Brown Medical School, Brown University, Providence, RI, USA
    J Am Osteopath Assoc 103:423-7. 2003
    ..While topical nasal corticosteroids have been shown to alleviate nasal obstruction effectively in patients with rhinitis who do not have CFS, it is unknown whether topical nasal corticosteroids will reduce CFS symptoms...
  71. pmc The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial
    Richard J Martin
    National Jewish Medical and Research Center, Denver, CO 80206, USA
    J Allergy Clin Immunol 119:73-80. 2007
    ..Although guidelines recommend anti-inflammatory therapy for persistent asthma, recent studies suggest that 25% to 35% of patients with asthma may not improve lung function with inhaled corticosteroids...