Research Topics
| Timothy J CraigSummaryAffiliation: Pennsylvania State University Country: USA Publications
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Publications
The role of montelukast on perennial allergic rhinitis and associated sleep disturbances and daytime somnolenceCarah B Santos
Penn State College of Medicine, Hershey, PA 17033, USA
Allergy Asthma Proc 29:140-5. 2008..In a small cohort of subjects, montelukast, when compared with placebo, improved the symptoms of PAR and reduced the fatigue and daytime somnolence associated with the disorder...
2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedemaTom Bowen
Departments of Medicine and Paediatrics, University of Calgary, Calgary, Alberta, Canada
Allergy Asthma Clin Immunol 6:24. 2010....- When is prophylaxis for hereditary angioedema necessary?Timothy Craig
Department of Medicine and Pediatrics, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania 17033, USA
Ann Allergy Asthma Immunol 102:366-72. 2009..To determine when newer agents, such as C1 esterase inhibitor protein (C1-INH), should be considered as prophylaxis to decrease hereditary angioedema (HAE) attacks as an alternative to androgens, which have significant adverse events... - Appraisal of danazol prophylaxis for hereditary angioedemaTimothy J Craig
Allergy Asthma and Immunology Section, Division of Pulmonary, Allergy, and Critical Care, Penn State University, Hershey, Pennsylvania, USA
Allergy Asthma Proc 29:225-31. 2008.... - Sleep impairment in allergic rhinitis, rhinosinusitis, and nasal polyposisTimothy J Craig
Pennsylvania State University College of Medicine, Hershey, PA 17033 0850, USA
Am J Otolaryngol 29:209-17. 2008..Such trials will help to identify the most effective therapies for sleep impairment in these 3 nasal conditions... - The safety profile of ciclesonide in the treatment of persistent asthmaTimothy Craig
Department of Medicine and Pediatrics, Penn State University, College of Medicine, Hershey, Pennsylvania 17033, USA
Allergy Asthma Proc 30:315-24. 2009..The favorable safety profile of CIC may allay patient and physician concern regarding ICS when using this agent. Guideline-recommended use of ICS medications may help optimize treatment outcomes in asthma... - Aeroallergen sensitization in asthma: prevalence and correlation with severityTimothy J Craig
Pennsylvania State University College of Medicine, Section of Allergy, Asthma, and Immunology, Hershey, Pennsylvania 17033 0853, USA
Allergy Asthma Proc 31:96-102. 2010..Higher levels of IgE and eNO and lower values of PC(20), are noted in patients with asthma and aeroallergen sensitization... - Congestion and sleep impairment in allergic rhinitisTimothy J Craig
Hershey Medical Center, Penn State University, 500 University Drive, Hershey, PA, 17033 0850, USA
Curr Allergy Asthma Rep 10:113-21. 2010..It explores the adverse effects of disturbed sleep on quality of life and how these conditions can be reduced by therapies that decrease congestion... - Treatment of Hereditary Angioedema: items that need to be addressed in practice parameterCallie Dagen
Section of Allergy Asthma and Immunology, Medicine and Pediatrics, Penn State University, 500 University Drive, Hershey, PA 17033, USA
Allergy Asthma Clin Immunol 6:11. 2010..Treatment of HAE in many parts of the world fall short and certain items need to be addressed in future guidelines... - Aeroallergen sensitization correlates with PC(20) and exhaled nitric oxide in subjects with mild-to-moderate asthmaTimothy J Craig
Division of Pulmonary Care, Pennsylvania State University College of Medicine, Hershey, PA 17033 0853, USA
J Allergy Clin Immunol 121:671-7. 2008..Aeroallergen sensitization in adult asthmatic patients from a wide geographic area has not been correlated with patients' characteristics, markers of airways inflammation, and lung function... 
Chronic fatigue syndrome: evaluation and treatmentTimothy Craig
Department of Medicine, Pennsylvania State University College of Medicine, Hershey 17033, USA
Am Fam Physician 65:1083-90. 2002..Therefore, treatment of CFS may be variable and should be tailored to each patient. Therapy should include exercise, diet, good sleep hygiene, antidepressants, and other medications, depending on the patient's presentation...- Recent advances in management and treatment of hereditary angioedemaNiti Sardana
Department of Pediatrics, Weill Cornell Medical Center, NewYork Presbyterian Hospital, New York, NY, USA
Pediatrics 128:1173-80. 2011..Morbidity and mortality are significant, and new and pending therapies are now available to reduce the risk associated with the disease... - Allergic rhinitis remains an important diseaseTimothy J Craig
Pennsylvania State University College of Medicine, Hershey, USA
J Am Osteopath Assoc 102:S1-2. 2002 - Asthma Clinical Research Network: lessons learnedTimothy Craig
Penn State University, Hershey, PA, USA
Mt Sinai J Med 78:671-82. 2011.... - A 64-year-old man with chronic obstructive pulmonary disease and an atypical rashEthan T Craig
Penn State College of Medicine, Penn State University, Hershey, Pennsylvania 17033, USA
Allergy Asthma Proc 32:325-8. 2011..Basic laboratory workup revealed conflicting information, leading to a diagnostic challenge discussed in this article. Ultimately, careful testing did reveal the diagnosis and the patient was treated accordingly... - Associations between air pollution and peak expiratory flow among patients with persistent asthmaZhengmin Qian
Department of Public Health Sciences, Pennsylvania State University, Hershey, Pennsylvania, USA
J Toxicol Environ Health A 72:39-46. 2009..The results show that the two medication regimens protected against the effects of PM(10). However, salmeterol increased the sensitivity to NO2 and triamcinalone enhanced the sensitivity to SO2... - Nasal obstruction, the airway, and the athleteLaura H Fisher
Department of Asthma, Allergy, and Immunology, The Pennsylvania State University, Milton S. Hershey Medical Center, Hershey, PA, USA
Clin Rev Allergy Immunol 29:151-8. 2005..Treatment of allergic rhinitis can improve sleep and foster productivity. Control of rhinitis and nasal congestion, which is obtained by various therapies, may reverse lower airway tendency to bronchoconstriction... - How do topical nasal corticosteroids improve sleep and daytime somnolence in allergic rhinitis?Timothy J Craig
Allergy, Asthma and Immunology Section, Penn State University, Hershey Medical Center, Hershey, PA 17033, USA
J Allergy Clin Immunol 116:1264-6. 2005..01) and daytime somnolence (P = .01). Thus, topical intranasal corticosteroids should be used to decrease nasal congestion and to improve sleep and daytime somnolence in patients manifesting these symptoms... - Per-attack reporting of prodromal symptoms concurrent with c1-inhibitor treatment of hereditary angioedema attacksMichael J Prematta
Allergy, Asthma and Immunology Section, Penn State University, Hershey, Pennsylvania, USA
Adv Ther 29:913-22. 2012..This study was designed to prospectively identify prodomal characteristics in patients voluntarily reporting such information around the time of seeking treatment for an acute HAE attack... - A practical approach to allergic rhinitis and sleep disturbance managementMichael J Davies
Department of Medicine, Division of Pulmonary, Allergy, and Critical Care, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA
Allergy Asthma Proc 27:224-30. 2006..Montelukast significantly improves both daytime and nighttime symptoms. AR treatment should endeavor to improve daytime and nighttime symptoms, sleep, and productivity thereby improving quality of life... - Allergic rhinitis and its effect on sleep, fatigue, and daytime somnolenceCarah B Santos
Allergy Research, Hershey Medical Center, Penn State University, Hershey, Pennsylvania 17033-0850, USA
Ann Allergy Asthma Immunol 97:579-86; quiz 586-9, 671. 2006..These future trials will serve to identify the most effective therapies that target the adverse effects of sleep impairment in this disorder... - The importance of rhinitis on sleep, daytime somnolence, productivity and fatigueLesley Woods
Division of Pulmonary, Allergy and Critical Care, Penn State University College of Medicine, Hershey, Pennsylvania 17033, USA
Curr Opin Pulm Med 12:390-6. 2006..Recently, montelukast, a leukotriene receptor antagonist, has been added to the therapies approved for allergic rhinitis. Montelukast significantly improves both daytime and nighttime symptoms... - Frequency, timing, and type of prodromal symptoms associated with hereditary angioedema attacksMichael J Prematta
Penn State Milton S Hershey Medical Center, Section of Allergy and Immunology, Hershey, Pennsylvania 17033 0850, USA
Allergy Asthma Proc 30:506-11. 2009..This high frequency suggests that prodromal symptoms could be a reliable indication to begin treatment to prevent an acute HAE attack, thus decreasing the anxiety associated with having an HAE attack... - Treatment response after repeated administration of C1 esterase inhibitor for successive acute hereditary angioedema attacksTimothy J Craig
Penn State University, Hershey, Pennsylvania 17033, USA
Allergy Asthma Proc 33:354-61. 2012..Treatment with 20 U/kg of C1-INH concentrate provided consistent treatment response in patients treated for multiple successive HAE attacks at any body location. (Clinicaltrials.gov identifier: NCT00292981)... - The role of pseudoephedrine on daytime somnolence in patients suffering from perennial allergic rhinitis (PAR)Amir A Sherkat
Penn State University, Hershey Medical Center, Hershey, Pennsylvania, USA
Ann Allergy Asthma Immunol 106:97-102. 2011..This inflammation of the nose leads to nasal congestion and a reduction in sleep quality, resulting in daytime somnolence... - Adverse events associated with intranasal influenza vaccine in the United StatesNeetu Vasu
Division of Pulmonary, Allergy and Critical Care, Penn State College of Medicine, Hershey Medical Center, Hershey, PA 17033, USA
Ther Adv Respir Dis 2:193-8. 2008..PubMed, Ovid, and Google searches were conducted. Searched articles relating to allergic reactions, asthma or food allergy, and LAIV were reviewed... - Assessing outcomes from the sleep disturbance associated with rhinitisEllen L Pratt
Section of Allergy, Asthma, and Immunology, Penn State Milton S Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA
Curr Opin Allergy Clin Immunol 7:249-56. 2007.... - Response to ecallantide treatment of acute attacks of hereditary angioedema based on time to intervention: results from the EDEMA clinical trialsErin Banta
Section of Allergy, Asthma, and Immunology, Penn State University, Hershey, Pennsylvania 17033, USA
Allergy Asthma Proc 32:319-24. 2011..4%). As with other therapies for HAE early ecallantide therapy is optimal. Treatment with ecallantide within 6 hours of symptom onset leads to more rapid and sustained improvement of symptoms... - Small bowel intussusception: an unusual presentation of angioedemaKusum Sharma
Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Penn State University Milton S Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA
Allergy Asthma Proc 31:84-7. 2010..The patient had a history of multiple episodes of swelling of extremities, face, and genitalia. The Allergy Consult Service was consulted for perioperative management of his angioedema... - Effects of poor sleep in allergic rhinitisLaura Fisher
Department of Medicine, Allergy, Asthma and Immunology H041, Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, USA
Curr Opin Allergy Clin Immunol 5:11-6. 2005..By understanding these mechanisms and by becoming familiar with effective treatments for allergic rhinitis that are beneficial in alleviating rather than worsening daytime somnolence, physicians may improve patient quality of life... - The perceived obstacles in performing patch test to detect allergic contact dermatitis: a comparison between community allergists and directors of allergy training programsGisoo Ghaffari
Allergy, Asthma and Immunology Clinic, Penn State College of Medicine, Milton S Hershey Medical Center, Hershey, Pennsylvania 17033 0850, USA
Ann Allergy Asthma Immunol 100:323-6. 2008..Patch testing (PT) is the gold standard test to detect allergic contact dermatitis. Despite its usefulness, it is not universally performed in allergy practices... - Is there a need for clinical guidelines in the United States for the diagnosis of hereditary angioedema and the screening of family members of affected patients?Michael L Lunn
Division of Pulmonary, Allergy, and Critical Care Medicine, Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania 17033, USA
Ann Allergy Asthma Immunol 104:211-4. 2010.... - Prospective study of rapid relief provided by C1 esterase inhibitor in emergency treatment of acute laryngeal attacks in hereditary angioedemaTimothy J Craig
Asthma and Respiratory Research, Penn State University, 500 University Drive, Hershey, PA 17033, USA
J Clin Immunol 30:823-9. 2010..We assessed the efficacy of C1-INH concentrate in the emergency treatment of rarely occurring acute laryngeal HAE attacks in a prospective, open-label clinical study... - The correlation between allergic rhinitis and sleep disturbanceTimothy J Craig
Allergy Section, Department of Medicine, Pennsylvania State University College of Medicine, Hershey, PA, USA
J Allergy Clin Immunol 114:S139-45. 2004..Montelukast significantly improves both daytime and nighttime symptoms. AR treatment should endeavor to improve daytime and nighttime symptoms, sleep, and productivity, thereby improving quality of life... - Treatment of hereditary angioedema: current perspectivesSvetlana I Krassilnikova
Section of Allergy, Asthma and Immunology, Penn State University, Milton S Hershey Medical Center, Hershey, PA 17033, USA
Recent Pat Inflamm Allergy Drug Discov 2:166-74. 2008..This review article also discusses some recent patents related to the filed... - Asthma and the diverMichael J Davies
Department of Asthma, Allergy, and Immunology, The Pennsylvania State University, Milton S. Hershey Medical Center, Hershey, PA, USA
Clin Rev Allergy Immunol 29:131-8. 2005..Under the right circumstances, the patient with asthma can safely participate in recreational diving without apparent increased risk of an asthma-related event... - ACE inhibitor-induced angioedemaMonali Vasekar
Department of Medicine, Penn State University, Hershey, PA 17033, USA
Curr Allergy Asthma Rep 12:72-8. 2012..In this article, we discuss the mechanism, prevalence, pathophysiology, and management of ACEiIA, with focus on newer therapies recently approved for HAE and how they may be effective for ACEiIA... - Mometasone furoate dry powder inhaler for the treatment of asthmaTracy B Fausnight
Penn State Hershey Medical Center, Penn State College of Medicine Pediatrics, Section of Allergy and Immunology, 500 University Drive, Hershey, PA 17033, USA
Expert Opin Pharmacother 12:2707-12. 2011..For patients with persistent asthma who require treatment with an inhaled corticosteroid, mometasone furoate is an excellent therapeutic choice... - A safety review of long-acting beta2-agonists in patients with asthmaNicholas L Rider
Allergy, Asthma, and Immunology Section, Penn State University Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA 17033-2360, USA
J Am Osteopath Assoc 106:562-7. 2006..However, when used in combination with an ICS, they decrease both rescue-medication use and symptoms, increase lung function, and act as steroid-sparing agents... - Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacksTimothy J Craig
Penn State University College of Medicine, Hershey, PA, USA
J Allergy Clin Immunol 124:801-8. 2009..Hereditary angioedema caused by C1 esterase inhibitor deficiency is a rare disorder... - The effect of topical nasal fluticasone on objective sleep testing and the symptoms of rhinitis, sleep, and daytime somnolence in perennial allergic rhinitisTimothy J Craig
Division of Medicine, Section of Pulmonary, Allergy, Critical Care, Pennsylvania State University, 500 University Drive, P.O. Box 850, Hershey, PA 17033, USA
Allergy Asthma Proc 24:53-8. 2003..However, fluticasone used at approved doses improves subjective sleep in patients with perennial allergic rhinitis without a change in the apnea/hypopnea index... - Early diagnosis is key in vancomycin-induced linear IgA bullous dermatosis and Stevens-Johnson syndromeDouglas H Jones
Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, PA 17033-0850, USA
J Am Osteopath Assoc 104:157-63. 2004..CONCLUSIONS: In cases of SJS or LABD that are difficult to distinguish clinically, the authors recommend performing a skin biopsy and direct immunofluorescence early to confirm the diagnosis so that effective treatment can be instituted... - A comparison of intranasal corticosteroid, leukotriene receptor antagonist, and topical antihistamine in reducing symptoms of perennial allergic rhinitis as assessed through the Rhinitis Severity ScoreNiti Sardana
College of Medicine, Penn State University, Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA
Allergy Asthma Proc 31:5-9. 2010..Systemic medication, montelukast, as expected, provided better relief for symptoms distant from the nasal cavity, and the antihistamine, azelastine, reduced rhinorrhea, more than either montelukast or budesonide... - A challenging diagnosis of alpha-1-antitrypsin deficiency: identification of a patient with a novel F/Null phenotypeMichael R Ringenbach
Department of Medicine, Section of Allergy and Immunology, The Pennsylvania State University Milton S, Hershey Medical Center, 500 University Dr, Hershey, PA 17033, USA
Allergy Asthma Clin Immunol 7:18. 2011.... - Summary of the International Multicenter Prospective Angioedema C1-inhibitor Trials 1 and 2 (IMPACT1 and 2)Svetlana Krassilnikova
Allergy, Asthma and Immunology, Pennsylvania State University, Hershey, PA 17033, USA
Expert Rev Clin Immunol 6:327-34. 2010..While final data from the IMPACT2 trial are not yet released, this article reviews currently available data from previous reports and abstract presentations... - Inflammatory responses in allergic rhinitis: traditional approaches and novel treatment strategiesSadeq A Quraishi
Department of Medicine, Section for Pulmonary, Allergy, and Immunology, Pennsylvania State University College of Medicine, Hershey, USA
J Am Osteopath Assoc 104:S7-15. 2004..As newer strategies emerge, treatment regimens for allergic rhinitis should continue to improve not only daytime symptoms, but also nighttime symptoms and sleep with the fewest possible adverse effects... - Assessment of care and disease management of patients with asthma in an overseas U.S. Army health clinicCherié M Inglis
The Milton S Hershey Medical Center, 500 University Drive, Hershey, PA 17033 2360, USA
Mil Med 169:558-61. 2004..Although our findings were encouraging, this study has highlighted that there is opportunity for improvement... - Fresh frozen plasma for the treatment of hereditary angioedemaMichael Prematta
Allergy, Asthma and Immunology Section, Penn State University, Hershey Medical Center, Hershey, Pennsylvania, USA
Ann Allergy Asthma Immunol 98:383-8. 2007..However, because FFP also contains other substrates, it has been hypothesized to have the potential to worsen or precipitate an acute attack of HAE... - Variability of prodromal signs and symptoms associated with hereditary angioedema attacks: a literature reviewJohn G Kemp
Department of Medicine, Section of Allergy, Asthma, and Immunology, Penn State University, College of Medicine, Hershey, Pennsylvania 17033, USA
Allergy Asthma Proc 30:493-9. 2009..There is considerable variability of the prodromal manifestations that may occur before or during HAE attacks. We have not found any evidence that their sensitivity and specificity for accurately predicting such attacks has been studied... - Treatment of hereditary angioedema with plasma-derived C1 inhibitorMichael J Prematta
Section of Allergy and Immunology, Penn State University, Milton S Hershey Medical Center, PA, USA
Ther Clin Risk Manag 4:975-82. 2008..Studies are still being conducted to establish its safety and efficacy as required by the FDA... - Statistical issues in clinical trials that involve the double-blind, placebo-controlled food challengeVernon M Chinchilli
Department of Health Evaluation Sciences, Penn State College of Medicine, Hershey, PA 17033 0855, USA
J Allergy Clin Immunol 115:592-7. 2005..Statistical software packages can be adapted to perform such analyses... - Liver enzyme elevation and normal pulmonary function in an adult with a declining forced expiratory volume in 1 secondNicholas L Rider
Division of Allergy and Immunology, The Pennsylvania State University Milton S Hershey Medical Center, Hershey, Pennsylvania, USA
Allergy Asthma Proc 29:345-8. 2008.... - The effect of intranasal steroid budesonide on the congestion-related sleep disturbance and daytime somnolence in patients with perennial allergic rhinitisFaina Gurevich
College of Medicine, Penn State University, Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA
Allergy Asthma Proc 26:268-74. 2005..01), and "refreshing and restorative" sleep (p = 0.04) in the active group. Nasal corticosteroid BUD is effective in reducing nasal congestion, daytime somnolence, and daytime fatigue, and improving sleep quality in PAR... - Poor sleep and daytime somnolence in allergic rhinitis: significance of nasal congestionSujani Kakumanu
Department of Medicine, Pulmonary, Allergy, Critical Care, Hershey, Pennsylvania 17033, USA
Am J Respir Med 1:195-200. 2002..Further research involving objective measures of sleep quality is necessary to determine the efficacy of medications in the treatment of allergic rhinitis associated with fatigue and daytime somnolence... - Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroidsAaron Deykin
Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
J Allergy Clin Immunol 115:720-7. 2005..Although inhaled corticosteroids (ICSs) are effective in preventing deterioration in asthma control, at least half of subjects with mild-to-moderate asthma will remain stable when these agents are discontinued... - Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthmaStephen C Lazarus
University of California, San Francisco, 505 Parnassus Avenue, M 1083, San Francisco, CA 94143 0111, USA
Am J Respir Crit Care Med 175:783-90. 2007..One-quarter to one-third of individuals with asthma smoke, which may affect response to therapy and contribute to poor asthma control... - Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthmaAaron Deykin
Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Am J Respir Crit Care Med 175:228-34. 2007..The elements of asthma control achieved by LABAs (improved lung function) and leukotriene receptor antagonists (LTRAs; protection against exacerbations) may be complementary as well... - Systemic effect comparisons of six inhaled corticosteroid preparationsRichard J Martin
National Jewish Medical and Research Center, Denver, Colorado 80206, USA
Am J Respir Crit Care Med 165:1377-83. 2002..This study represents the first step in evaluation of ICS efficacy based on equisystemic (cortisol suppression) effects of a given ICS, rather than doses judged arbitrarily to be comparable on a microgram basis... - beta-Adrenergic receptor polymorphisms and response to salmeterolMichael E Wechsler
Brigham and Women s Hospital, 75 Francis Street, Boston, MA, 02115, USA
Am J Respir Crit Care Med 173:519-26. 2006..Several studies suggest that patients with asthma who are homozygous for arginine at the 16th position of the beta2-adrenergic receptor may not benefit from short-acting beta-agonists... - Effect of topical nasal corticosteroids on patients with chronic fatigue syndrome and rhinitisSujani S Kakumanu
Division of Biology and Medicine, Brown Medical School, Brown University, Providence, RI, USA
J Am Osteopath Assoc 103:423-7. 2003..These results indicate that the nonallergic rhinitis seen in patients with CFS may arise from a mechanism other than chronic inflammation... - Significant variability in response to inhaled corticosteroids for persistent asthmaStanley J Szefler
National Jewish Medical and Research Center, Department of Pediatrics, Denver, CO 80206, USA
J Allergy Clin Immunol 109:410-8. 2002..It is possible that higher doses of ICSs are necessary to manage more severe patients or to achieve goals of therapy not evaluated in this study, such as prevention of asthma exacerbations... - Improved immunotherapy with a rapid allergen vaccination schedule: a study of 137 patientsWilliam Smits
Allergy and Asthma Center, 7230 Engle Rd, Suite 300, Fort Wayne, IN 46804 2234, USA
Ear Nose Throat J 82:881-7. 2003..Moreover, RAV is associated with less morbidity and less expense. Our findings should encourage physicians who treat allergy patients to give further consideration to using RAV... - Inhaled mometasone furoate reduces oral prednisone usage and improves lung function in severe persistent asthmaJill P Karpel
North Shore University Hospital, New Hyde Park, NY 11040, USA
Respir Med 101:628-37. 2007..The reduction of oral prednisone use by mometasone furoate (MF) delivered by HFA-227 metered dose inhaler (MDI) was examined in oral corticosteroid (OCS)-dependent patients with severe persistent asthma... - Clinical and entomological factors influence the outcome of sting challenge studiesDavid B K Golden
Johns Hopkins Asthma and Allergy Center, Baltimore, MD 21224, USA
J Allergy Clin Immunol 117:670-5. 2006..The reported frequency of systemic reactions to challenge sting varies greatly... - Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trialElliot Israel
Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Lancet 364:1505-12. 2004..However, the existence of any genotype-dependent difference has not been tested in a prospective clinical trial... - The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trialRichard J Martin
National Jewish Medical and Research Center, Denver, CO 80206, USA
J Allergy Clin Immunol 119:73-80. 2007..Although guidelines recommend anti-inflammatory therapy for persistent asthma, recent studies suggest that 25% to 35% of patients with asthma may not improve lung function with inhaled corticosteroids... - Daily versus as-needed corticosteroids for mild persistent asthmaHomer A Boushey
University of California at San Francisco, San Francisco, USA
N Engl J Med 352:1519-28. 2005..Further studies are required to determine whether this novel approach to treatment should be recommended...