Laura Carrel

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. ncbi request reprint Evolutionary biology: chromosome chain makes a link
    Laura Carrel
    Nature 432:817-8. 2004
  2. ncbi request reprint X-inactivation profile reveals extensive variability in X-linked gene expression in females
    Laura Carrel
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    Nature 434:400-4. 2005
  3. ncbi request reprint Molecular biology. "X"-rated chromosomal rendezvous
    Laura Carrel
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Science 311:1107-9. 2006
  4. pmc Genomic environment predicts expression patterns on the human inactive X chromosome
    Laura Carrel
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
    PLoS Genet 2:e151. 2006
  5. pmc Escape from X chromosome inactivation is an intrinsic property of the Jarid1c locus
    Nan Li
    Department of Biochemistry and Molecular Biology and Intercollege Graduate Program in Genetics, Pennsylvania State College of Medicine, Hershey, PA 17033, USA
    Proc Natl Acad Sci U S A 105:17055-60. 2008
  6. doi request reprint Dosage compensation and gene expression on the mammalian X chromosome: one plus one does not always equal two
    Katie E Prothero
    Department of Biochemistry and Molecular Biology, Penn State College of Medicine, Hershey, PA 17033, USA
    Chromosome Res 17:637-48. 2009
  7. pmc An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells
    Lisa L Hall
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Proc Natl Acad Sci U S A 99:8677-82. 2002
  8. ncbi request reprint An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase
    Kiyoshi Hidaka
    Inositide Signaling Section, Laboratory of Signal Transduction, NIEHS, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    J Biol Chem 277:32730-8. 2002
  9. pmc The DNA sequence of the human X chromosome
    Mark T Ross
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nature 434:325-37. 2005

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Evolutionary biology: chromosome chain makes a link
    Laura Carrel
    Nature 432:817-8. 2004
  2. ncbi request reprint X-inactivation profile reveals extensive variability in X-linked gene expression in females
    Laura Carrel
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    Nature 434:400-4. 2005
    ..This suggests a remarkable and previously unsuspected degree of expression heterogeneity among females...
  3. ncbi request reprint Molecular biology. "X"-rated chromosomal rendezvous
    Laura Carrel
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Science 311:1107-9. 2006
  4. pmc Genomic environment predicts expression patterns on the human inactive X chromosome
    Laura Carrel
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
    PLoS Genet 2:e151. 2006
    ..Thus, our results strongly support the role of L1s in X inactivation, yet indicate that a chromatin microenvironment composed of multiple genomic sequence elements determines expression status of X chromosome genes...
  5. pmc Escape from X chromosome inactivation is an intrinsic property of the Jarid1c locus
    Nan Li
    Department of Biochemistry and Molecular Biology and Intercollege Graduate Program in Genetics, Pennsylvania State College of Medicine, Hershey, PA 17033, USA
    Proc Natl Acad Sci U S A 105:17055-60. 2008
    ..This transgene approach will enable further dissection of key elements of escape domains and allow rigorous testing of specific genomic sequences on inactive X expression...
  6. doi request reprint Dosage compensation and gene expression on the mammalian X chromosome: one plus one does not always equal two
    Katie E Prothero
    Department of Biochemistry and Molecular Biology, Penn State College of Medicine, Hershey, PA 17033, USA
    Chromosome Res 17:637-48. 2009
    ..Moreover, escape genes give insight into how X chromosome inactivation is spread and maintained on the X...
  7. pmc An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells
    Lisa L Hall
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Proc Natl Acad Sci U S A 99:8677-82. 2002
    ..These results have fundamental significance for understanding genomic programming in early development...
  8. ncbi request reprint An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase
    Kiyoshi Hidaka
    Inositide Signaling Section, Laboratory of Signal Transduction, NIEHS, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    J Biol Chem 277:32730-8. 2002
    ..The hDIPP3 pair add tissue-specific diversity to the molecular mechanisms regulating diphosphoinositol polyphosphate turnover...
  9. pmc The DNA sequence of the human X chromosome
    Mark T Ross
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nature 434:325-37. 2005
    ..Of this number, 168 have been explained by mutations in 113 X-linked genes, which in many cases were characterized with the aid of the DNA sequence...