Lauren M Sparks

Summary

Affiliation: Pennington Biomedical Research Center
Country: USA

Publications

  1. pmc Relation of adipose tissue to metabolic flexibility
    Lauren M Sparks
    Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Diabetes Res Clin Pract 83:32-43. 2009
  2. ncbi request reprint High-fat/low-carbohydrate diets regulate glucose metabolism via a long-term transcriptional loop
    Lauren M Sparks
    Department of Biological Sciences, Louisiana State University and Agricultural and Mechanical College, Baton Rouge, LA, USA
    Metabolism 55:1457-63. 2006
  3. ncbi request reprint Effect of adipose tissue on the sexual dimorphism in metabolic flexibility
    Lauren M Sparks
    Experimental Endocrinology, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Metabolism 58:1564-71. 2009
  4. pmc Remodeling lipid metabolism and improving insulin responsiveness in human primary myotubes
    Lauren M Sparks
    Molecular and Experimental Endocrinology Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America
    PLoS ONE 6:e21068. 2011
  5. pmc Low macrophage accumulation in skeletal muscle of obese type 2 diabetics and elderly subjects
    Charmaine S Tam
    Pennington Biomedical Research Center, Baton Rouge, LA, USA
    Obesity (Silver Spring) 20:1530-3. 2012
  6. ncbi request reprint A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
    Lauren M Sparks
    Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
    Diabetes 54:1926-33. 2005

Detail Information

Publications6

  1. pmc Relation of adipose tissue to metabolic flexibility
    Lauren M Sparks
    Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Diabetes Res Clin Pract 83:32-43. 2009
    ....
  2. ncbi request reprint High-fat/low-carbohydrate diets regulate glucose metabolism via a long-term transcriptional loop
    Lauren M Sparks
    Department of Biological Sciences, Louisiana State University and Agricultural and Mechanical College, Baton Rouge, LA, USA
    Metabolism 55:1457-63. 2006
    ..Combined, these results suggest a mechanism whereby HF/LCD regulates the genes necessary for glucose utilization and storage vis-รก-vis transcriptional control...
  3. ncbi request reprint Effect of adipose tissue on the sexual dimorphism in metabolic flexibility
    Lauren M Sparks
    Experimental Endocrinology, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Metabolism 58:1564-71. 2009
    ..Combined, these results provide evidence for a role of adipose tissue characteristics in the sexual dimorphism of metabolic flexibility...
  4. pmc Remodeling lipid metabolism and improving insulin responsiveness in human primary myotubes
    Lauren M Sparks
    Molecular and Experimental Endocrinology Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States of America
    PLoS ONE 6:e21068. 2011
    ..We hypothesized that activation of cAMP/PKA and calcium signaling pathways in cultured human myotubes would provide further insight into regulation of lipid storage, lipolysis, lipid oxidation and insulin responsiveness...
  5. pmc Low macrophage accumulation in skeletal muscle of obese type 2 diabetics and elderly subjects
    Charmaine S Tam
    Pennington Biomedical Research Center, Baton Rouge, LA, USA
    Obesity (Silver Spring) 20:1530-3. 2012
    ..In conclusion, we found little evidence of macrophage accumulation in skeletal muscle in obese T2D subjects or in elderly individuals. A 9-month exercise program was not associated with a decrease in macrophage content...
  6. ncbi request reprint A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
    Lauren M Sparks
    Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
    Diabetes 54:1926-33. 2005
    ..These changes mimic those observed in diabetes and insulin resistance and, if sustained, may result in mitochondrial dysfunction in the prediabetic/insulin-resistant state...