Hanna Shevalye

Summary

Affiliation: Pennington Biomedical Research Center
Country: USA

Publications

  1. pmc Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy
    Sergey Lupachyk
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA
    Diabetes 62:944-52. 2013
  2. doi Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative-nitrosative stress and p38 MAPK activation
    Roman Stavniichuk
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, USA
    Exp Neurol 230:106-13. 2011
  3. pmc Na+/H+ exchanger 1 inhibition reverses manifestation of peripheral diabetic neuropathy in type 1 diabetic rats
    Sergey Lupachyk
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA
    Am J Physiol Endocrinol Metab 305:E396-404. 2013
  4. pmc New therapeutic and biomarker discovery for peripheral diabetic neuropathy: PARP inhibitor, nitrotyrosine, and tumor necrosis factor-{alpha}
    Viktor R Drel
    Pennington Biomedical Research Center, Louisiana State University System, 6400 Perkins Road, Baton Rouge, Louisiana 70808, USA
    Endocrinology 151:2547-55. 2010
  5. pmc Poly(Adenosine 5'-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy
    Viktor R Drel
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana 70808, USA
    Endocrinology 150:5273-83. 2009
  6. pmc Evaluation of PMI-5011, an ethanolic extract of Artemisia dracunculus L., on peripheral neuropathy in streptozotocin-diabetic mice
    Pierre Watcho
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
    Int J Mol Med 27:299-307. 2011
  7. doi Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease
    Hanna Shevalye
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, USA
    Biochim Biophys Acta 1802:1020-7. 2010
  8. pmc Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress
    Hanna Shevalye
    Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, Louisiana 70808, USA
    Endocrinology 153:1152-61. 2012
  9. pmc Metanx alleviates multiple manifestations of peripheral neuropathy and increases intraepidermal nerve fiber density in Zucker diabetic fatty rats
    Hanna Shevalye
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA
    Diabetes 61:2126-33. 2012
  10. pmc Different roles of 12/15-lipoxygenase in diabetic large and small fiber peripheral and autonomic neuropathies
    Irina G Obrosova
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
    Am J Pathol 177:1436-47. 2010

Collaborators

Detail Information

Publications14

  1. pmc Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy
    Sergey Lupachyk
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA
    Diabetes 62:944-52. 2013
    ..Our findings reveal an important role of endoplasmic reticulum stress in the development of diabetic peripheral neuropathy and identify a potential new therapeutic target...
  2. doi Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative-nitrosative stress and p38 MAPK activation
    Roman Stavniichuk
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, USA
    Exp Neurol 230:106-13. 2011
    ..The findings provide rationale for studying hydroxyflavones with an improved pharmacological profile as potential treatments for diabetic neuropathy and other diabetic complications...
  3. pmc Na+/H+ exchanger 1 inhibition reverses manifestation of peripheral diabetic neuropathy in type 1 diabetic rats
    Sergey Lupachyk
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA
    Am J Physiol Endocrinol Metab 305:E396-404. 2013
    ....
  4. pmc New therapeutic and biomarker discovery for peripheral diabetic neuropathy: PARP inhibitor, nitrotyrosine, and tumor necrosis factor-{alpha}
    Viktor R Drel
    Pennington Biomedical Research Center, Louisiana State University System, 6400 Perkins Road, Baton Rouge, Louisiana 70808, USA
    Endocrinology 151:2547-55. 2010
    ....
  5. pmc Poly(Adenosine 5'-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy
    Viktor R Drel
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana 70808, USA
    Endocrinology 150:5273-83. 2009
    ..These findings provide rationale for development and further studies of PARP inhibitors and PARP inhibitor-containing combination therapies...
  6. pmc Evaluation of PMI-5011, an ethanolic extract of Artemisia dracunculus L., on peripheral neuropathy in streptozotocin-diabetic mice
    Pierre Watcho
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
    Int J Mol Med 27:299-307. 2011
    ..In conclusion, PMI-5011, a safe and non-toxic botanical extract, may find use in the treatment of diabetic peripheral neuropathy...
  7. doi Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease
    Hanna Shevalye
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, USA
    Biochim Biophys Acta 1802:1020-7. 2010
    ..In conclusion, PARP-1-/- gene deficiency alleviates although does not completely prevent diabetic kidney disease...
  8. pmc Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress
    Hanna Shevalye
    Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, Louisiana 70808, USA
    Endocrinology 153:1152-61. 2012
    ....
  9. pmc Metanx alleviates multiple manifestations of peripheral neuropathy and increases intraepidermal nerve fiber density in Zucker diabetic fatty rats
    Hanna Shevalye
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA
    Diabetes 61:2126-33. 2012
    ..Clinical studies are needed to determine if Metanx finds use in management of diabetic peripheral neuropathy...
  10. pmc Different roles of 12/15-lipoxygenase in diabetic large and small fiber peripheral and autonomic neuropathies
    Irina G Obrosova
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
    Am J Pathol 177:1436-47. 2010
    ..This should be considered in the selection of endpoints for future clinical trials of 12/15-lipoxygenase inhibitors...
  11. pmc Interplay of sorbitol pathway of glucose metabolism, 12/15-lipoxygenase, and mitogen-activated protein kinases in the pathogenesis of diabetic peripheral neuropathy
    Roman Stavniichuk
    Pennington Biomedical Research Center, Louisiana State University System, 6400 Perkins Road, Baton Rouge, LA 70808, USA
    Biochem Pharmacol 83:932-40. 2012
    ....
  12. pmc Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies
    Roman Stavniichuk
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
    Free Radic Biol Med 49:1036-45. 2010
    ..Its presence in human Schwann cells and upregulation by high glucose suggest a potential involvement in human disease...
  13. pmc PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: correlation with peripheral nerve function
    Sergey Lupachyk
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
    Free Radic Biol Med 50:1400-9. 2011
    ..The findings reveal the important role of PARP activation in systemic oxidative stress and 4-hydroxynonenal adduct accumulation in diabetic peripheral neuropathy...
  14. doi Poly(ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat model
    Hanna Shevalye
    Pennington Biomedical Research Center, Louisiana State University System, 6400 Perkins Road, Baton Rouge, LA 70808, United States
    Biochem Pharmacol 79:1007-14. 2010
    ..These findings provide rationale for development and further studies of PARP inhibitors and PARP inhibitor-containing combination therapies, for prevention and treatment of diabetic nephropathy...