Research Topics
| Donna RyanSummaryAffiliation: Pennington Biomedical Research Center Country: USA Publications
Research Grants
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Detail Information
Publications
Use of sibutramine to treat obesityDonna H Ryan
Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
Prim Care 30:405-26, viii. 2003..Sibutramine can be a useful tool in the obesity treatment toolbox if used by knowledgeable practitioners...
Pharmacologic treatment options for obesity: what is old is new againDonna H Ryan
Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA, 70808, USA
Curr Hypertens Rep 15:182-9. 2013..All the new drugs under discussion are re-fittings of old agents or fresh approaches to old targets; thus, what is old is new again in the pharmacotherapy of obesity...- Nonsurgical weight loss for extreme obesity in primary care settings: results of the Louisiana Obese Subjects StudyDonna H Ryan
Pennington Biomedical Research Center of Louisiana State University System, Baton Rouge, LA 70808, USA
Arch Intern Med 170:146-54. 2010.... - Medical management of obesity in women: office-based approaches to weight managementDonna H Ryan
Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
Clin Obstet Gynecol 47:914-27; discussion 980-1. 2004 - Use of sibutramine and other noradrenergic and serotonergic drugs in the management of obesityD H Ryan
Pennington Biomedical Research Center, Baton Rouge, LA, USA
Endocrine 13:193-9. 2000.... - Clinical use of sibutramineDonna H Ryan
Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana 70808, USA
Drugs Today (Barc) 40:41-54. 2004..Sibutramine is a useful adjunct to diet and physical activity approaches and can help selected patients achieve and maintain weight loss with concomitant health benefits... 
An environmental intervention to prevent excess weight gain in African-American students: a pilot studyRobert L Newton
Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808, USA
Am J Health Promot 24:340-3. 2010..To examine the influence of an environmental intervention to prevent excess weight gain in African-American children...- Two-year internet-based randomized controlled trial for weight loss in African-American girlsDonald A Williamson
Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
Obesity (Silver Spring) 14:1231-43. 2006..A randomized controlled trial tested the efficacy of an internet-based lifestyle behavior modification program for African-American girls over a 2-year period of intervention... - Prevalence of risk factors for metabolic syndrome in adolescents: National Health and Nutrition Examination Survey (NHANES), 2001-2006William D Johnson
Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
Arch Pediatr Adolesc Med 163:371-7. 2009..To investigate the prevalence of distinct combinations of components of the metabolic syndrome among adolescents... - Wise Mind project: a school-based environmental approach for preventing weight gain in childrenDonald A Williamson
Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70734, USA
Obesity (Silver Spring) 15:906-17. 2007.... - Military services fitness database: development of a computerized physical fitness and weight management database for the U.S. ArmyDonald A Williamson
Pennington Biomedical Research Center, Baton Rouge, LA 70808 4124, USA
Mil Med 174:1-8. 2009..A 2.5-year pilot test of the MSFD indicated that it monitors population and individual trends of changing body weight, %BF, and fitness in a military population... - The effects of triiodothyronine on bone metabolism in healthy ambulatory menSteven R Smith
Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
Thyroid 13:357-64. 2003..4% (p = 0.08). Bone mineral density showed no change. We conclude that T(3) accelerates bone turnover and that bone formation does not increase acutely to prevent bone loss... - Comparison of body composition methods in obese African-American womenRobert L Newton
Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, LA 70808, USA
Obesity (Silver Spring) 14:415-22. 2006..To compare the accuracy of percentage body fat (%BF) estimates between bioelectrical impedance analysis (BIA) and DXA in obese African-American women... - A pilot church-based weight loss program for African-American adults using church members as health educators: a comparison of individual and group interventionBetty M Kennedy
Health Behavior Dept, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
Ethn Dis 15:373-8. 2005..The purpose of this study was to examine a church-based intervention employing a 6-month pilot weight loss program as a strategy to improve health of African-American adults... - A primary care weight management intervention for low-income African-American womenPamela Davis Martin
Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana 70808 4124, USA
Obesity (Silver Spring) 14:1412-20. 2006..To determine whether a tailored weight management program, addressing the needs of obese, low-income African-American women, would produce greater weight loss than standard medical care... - Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trialXavier Pi-Sunyer
St Luke s Roosevelt Hospital Center, USA
Diabetes Care 30:1374-83. 2007..This report describes 1-year changes in CVD risk factors in a trial designed to examine the long-term effects of an intensive lifestyle intervention on the incidence of major CVD events... - Distribution of glucokinase, glucose transporter GLUT2, sulfonylurea receptor-1, glucagon-like peptide-1 receptor and neuropeptide Y messenger RNAs in rat brain by quantitative real time RT-PCRBing Li
Pennington Biomedical Research Center C1038, Louisiana State University, 6400 Perkins Rd, Baton Rouge 70808, USA
Brain Res Mol Brain Res 113:139-42. 2003..In this study, we combined tissue micropunch and real time reverse transcription polymerase chain reaction (RT-PCR), and measured GK, GLUT2, SUR1, GLP-1R and NPY mRNA expression in discrete areas in the hypothalamus and the hindbrain... - Drug treatment of the overweight patientGeorge A Bray
Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
Gastroenterology 132:2239-52. 2007..In addition there are several drugs and drug combinations in phase 2 or phase 2 trials that will be reported on in the coming years... - Louisiana (LA) Health: design and methods for a childhood obesity prevention program in rural schoolsDonald A Williamson
Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
Contemp Clin Trials 29:783-95. 2008..The study will also recruit a similar sample of students to measure changes in body weight relative to height, gender, and age over the same three-year period... - Politics of the obesity epidemic: results of the 2003 Louisiana Physicians SurveyDonna H Ryan
Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
J La State Med Soc 157:S28-33. 2005..However, our survey indicates that support among Louisiana physicians for obesity-related policy is not equal to support for policies directed against helmet and smoking laws... - Mediators of weight loss in a family-based intervention presented over the internetMarney A White
Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, USA
Obes Res 12:1050-9. 2004..It was hypothesized that variables such as program adherence, dietary self-efficacy, psychological factors, and family environment factors would mediate the effect of the experimental condition on weight loss... - Dietary fish oil does not protect rats exposed to restraint or sleep deprivation stressEmilia Papakonstantinou
Department of Foods and Nutrition, University of Georgia, Dawson Hall, Athens, GA 30602, USA
Physiol Behav 78:759-65. 2003..In conclusion, our results suggest that high levels of dietary FO do not improve the response to stress in rats exposed to mixed stressors... - Americans on diet: results from the 1994-1996 Continuing Survey of Food Intakes by IndividualsSahasporn Paeratakul
Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, LA 70808, USA
J Am Diet Assoc 102:1247-51. 2002..Our results suggest that the dieters generally consumed a more nutrient-dense diet than the nondieters but still low in certain nutrients... - Short-term food restriction and refeeding alter expression of genes likely involved in brain glucosensingJun Zhou
Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana 70808, USA
Exp Biol Med (Maywood) 228:943-50. 2003..The results indicate that putative glucosensing (GK, Glut-2, and Glp-1R) gene expression in the hypothalamus and brainstem is reduced in response to food intake, depending on prior nutritional status... - Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetesDonna H Ryan
Pennington Biomedical Research Center
Control Clin Trials 24:610-28. 2003..Other outcomes include components of CVD risk, cost and cost-effectiveness, diabetes control and complications, hospitalizations, intervention processes, and quality of life... - Fast-food consumption among US adults and children: dietary and nutrient intake profileSahasporn Paeratakul
Nutritional Epidemiology, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808, USA
J Am Diet Assoc 103:1332-8. 2003..To examine the dietary profile associated with fast-food use. To compare the dietary intake of individuals on the day that they ate fast food with the day that fast food was not eaten... - The influence of different fats and fatty acids on obesity, insulin resistance and inflammationGeorge A Bray
Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
J Nutr 132:2488-91. 2002..One important conclusion from this review is that both total fat and individual fatty acids have to be considered when reaching conclusions about dietary fat and obesity... - Expression levels of genes likely involved in glucose-sensing in the obese Zucker rat brainIwona Bogacka
Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, LA 70808, USA
Nutr Neurosci 7:67-74. 2004..Furthermore, the hindbrain may be an important site for glucose-sensing where major phenotypic changes occur for glucose-sensing genes expression... - Sex, race/ethnicity, socioeconomic status, and BMI in relation to self-perception of overweightSahasporn Paeratakul
Nutritional Epidemiology, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge 70808, USA
Obes Res 10:345-50. 2002.... - Changes in food intake and body weight associated with basic combat trainingDonald A Williamson
Pennington Biomedical Research Center, 64000 Perkins Road, Baton Rouge, LA 70808, USA
Mil Med 167:248-53. 2002..These findings suggest that the overall effect of BCT was a trend toward improvement of healthy eating and healthy body weight... - Weight loss in rats exposed to repeated acute restraint stress is independent of energy or leptin statusRuth B S Harris
Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
Am J Physiol Regul Integr Comp Physiol 282:R77-88. 2002..These results indicate that repeated acute stress induces a chronic change in weight independent of stress-induced hypophagia and may represent a change in homeostasis initiated by repeated acute activation of the central CRF system... - The relationship among risk factor clustering, abdominal obesity, and residual risk for cardiovascular eventsDonna H Ryan
Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
Rev Cardiovasc Med 8:9-16. 2007..It is a potential therapeutic target to reduce residual cardiometabolic risk. Waist circumference has been shown to be a strong correlate of abdominal obesity, and measurement is a useful tool for the assessment of cardiometabolic risk... - Increased glucocorticoid response to a novel stress in rats that have been restrainedRuth B S Harris
Department of Foods and Nutrition, Dawson Hall, University of Georgia, Athens, GA 30602, USA
Physiol Behav 81:557-68. 2004..Therefore, multiple aspects of the stress response may be exaggerated in these animals and contribute to the chronic reduction in body weight... - Metabolic flexibility in response to glucose is not impaired in people with type 2 diabetes after controlling for glucose disposal rateJose E Galgani
Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
Diabetes 57:841-5. 2008.... - Compensatory growth of adipose tissue after partial lipectomy: involvement of serum factorsDorothy B Hausman
Department of Foods and Nutrition, University of Georgia, Athens, Georgia 30602, USA
Exp Biol Med (Maywood) 229:512-20. 2004..Thus, compensatory adipose tissue growth after lipectomy may be mediated, in part, by blood-borne factors that are derived from tissues other than adipose tissue... - Rats fed only during the light period are resistant to stress-induced weight lossRuth B S Harris
Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
Physiol Behav 76:543-50. 2002..This study demonstrates that stress-induced weight loss only occurs when rats have food available during their normal feeding period (dark phase) and is not determined by increased corticosterone release... - A new dental approach for reducing food intakeHeather M Walden
Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
Obes Res 12:1773-80. 2004..DISCUSSION: These findings suggest that use of this tool during meals significantly reduced food intake. This reduction of food intake was not associated with changes in ratings of hunger or satiety...
Research Grants
- Louisiana Clinical and Translational Science Center Planning PhaseDonna Ryan; Fiscal Year: 2006..In addition to activities serving Louisiana, the LA CaTS Center will serve as an incubator to foster the development of innovative tools and information technologies that can benefit the field. ..