Christopher Morrison

Summary

Affiliation: Pennington Biomedical Research Center
Country: USA

Publications

  1. doi request reprint Interaction between exercise and leptin in the treatment of obesity
    Christopher Morrison
    Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    Diabetes 57:534-5. 2008
  2. pmc Homeostatic regulation of protein intake: in search of a mechanism
    Christopher D Morrison
    Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    Am J Physiol Regul Integr Comp Physiol 302:R917-28. 2012
  3. pmc Leptin resistance and the response to positive energy balance
    Christopher D Morrison
    Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Physiol Behav 94:660-3. 2008
  4. pmc Increased hypothalamic protein tyrosine phosphatase 1B contributes to leptin resistance with age
    Christopher D Morrison
    Neurosignaling Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
    Endocrinology 148:433-40. 2007
  5. pmc Leptin signaling in brain: A link between nutrition and cognition?
    Christopher D Morrison
    Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Biochim Biophys Acta 1792:401-8. 2009
  6. ncbi request reprint The brain, appetite, and obesity
    Hans Rudolf Berthoud
    Neurobiology of Nutrition Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA
    Annu Rev Psychol 59:55-92. 2008
  7. ncbi request reprint Orexin inputs to caudal raphé neurons involved in thermal, cardiovascular, and gastrointestinal regulation
    Hans Rudolf Berthoud
    Neurobiology of Nutrition Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808, USA
    Histochem Cell Biol 123:147-56. 2005
  8. ncbi request reprint Selective tissue uptake of agouti-related protein(82-131) and its modulation by fasting
    Weihong Pan
    Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, 70808, USA
    Endocrinology 146:5533-9. 2005
  9. ncbi request reprint Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling
    Christopher D Morrison
    University of Washington, Harborview Medical Center, Box 359757, 325 Ninth Ave, Seattle, WA 98108, USA
    Am J Physiol Endocrinol Metab 289:E1051-7. 2005
  10. ncbi request reprint Neurobiology of nutrition and obesity
    Christopher D Morrison
    Neurosignaling Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana 70808, USA
    Nutr Rev 65:517-34. 2007

Research Grants

  1. Hypothalamic Leptin and Insulin Signaling
    Christopher Morrison; Fiscal Year: 2007
  2. Neural regulation of protein ingestion
    Christopher D Morrison; Fiscal Year: 2010

Detail Information

Publications16

  1. doi request reprint Interaction between exercise and leptin in the treatment of obesity
    Christopher Morrison
    Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    Diabetes 57:534-5. 2008
  2. pmc Homeostatic regulation of protein intake: in search of a mechanism
    Christopher D Morrison
    Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    Am J Physiol Regul Integr Comp Physiol 302:R917-28. 2012
    ....
  3. pmc Leptin resistance and the response to positive energy balance
    Christopher D Morrison
    Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Physiol Behav 94:660-3. 2008
    ....
  4. pmc Increased hypothalamic protein tyrosine phosphatase 1B contributes to leptin resistance with age
    Christopher D Morrison
    Neurosignaling Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
    Endocrinology 148:433-40. 2007
    ..05). These data are consistent with the hypothesis that increases in PTP1B contribute to hypothalamic leptin resistance as rats transition into middle age...
  5. pmc Leptin signaling in brain: A link between nutrition and cognition?
    Christopher D Morrison
    Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Biochim Biophys Acta 1792:401-8. 2009
    ....
  6. ncbi request reprint The brain, appetite, and obesity
    Hans Rudolf Berthoud
    Neurobiology of Nutrition Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana, USA
    Annu Rev Psychol 59:55-92. 2008
    ..The predisposition to develop obesity can theoretically result from any pathological malfunction or lack of adaptation to changing environments of this highly complex system...
  7. ncbi request reprint Orexin inputs to caudal raphé neurons involved in thermal, cardiovascular, and gastrointestinal regulation
    Hans Rudolf Berthoud
    Neurobiology of Nutrition Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808, USA
    Histochem Cell Biol 123:147-56. 2005
    ....
  8. ncbi request reprint Selective tissue uptake of agouti-related protein(82-131) and its modulation by fasting
    Weihong Pan
    Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, 70808, USA
    Endocrinology 146:5533-9. 2005
    ..Thus, the differential uptake of AgRP by peripheral organs could be a regulated process that is modulated by food deprivation...
  9. ncbi request reprint Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling
    Christopher D Morrison
    University of Washington, Harborview Medical Center, Box 359757, 325 Ninth Ave, Seattle, WA 98108, USA
    Am J Physiol Endocrinol Metab 289:E1051-7. 2005
    ..In addition, these data suggest that leptin activation of STAT3 is insufficient to inhibit expression of Npy or Agrp in the absence of PI3K signaling...
  10. ncbi request reprint Neurobiology of nutrition and obesity
    Christopher D Morrison
    Neurosignaling Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana 70808, USA
    Nutr Rev 65:517-34. 2007
    ....
  11. ncbi request reprint Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons
    Gregory J Morton
    Department of Medicine, Harborview Medical Center and University of Washington, Seattle, WA 98104, USA
    Cell Metab 2:411-20. 2005
    ..These findings suggest that hypothalamic leptin signaling is an important determinant of glucose metabolism and that the underlying neuronal mechanism involves PI3K...
  12. pmc Effects of chromium picolinate on food intake and satiety
    Stephen D Anton
    Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana, USA
    Diabetes Technol Ther 10:405-12. 2008
    ..Chromium picolinate (CrPic) has been shown to attenuate weight gain, but the mechanism underlying this effect is unknown...
  13. pmc Amino acids inhibit Agrp gene expression via an mTOR-dependent mechanism
    Christopher D Morrison
    Neurobehavior Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Am J Physiol Endocrinol Metab 293:E165-71. 2007
    ..01). Taken together, these observations indicate that amino acids can act within the brain to inhibit food intake and that a direct, mTOR-dependent inhibition of Agrp gene expression may contribute to this effect...
  14. ncbi request reprint The agouti-related protein and its role in energy homeostasis
    Adrian M Stütz
    Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
    Peptides 26:1771-81. 2005
    ..This review summarizes recent advances in the biochemical and physiological properties of AGRP in an effort to enhance our understanding of the role this powerful neuropeptide plays in mammalian energy homeostasis...
  15. ncbi request reprint Effect of uncontrolled diabetes on plasma ghrelin concentrations and ghrelin-induced feeding
    Richard W Gelling
    Department of Medicine, Harborview Medical Center, 325 Ninth Avenue, Box 359657, Seattle, Washington 98104, USA
    Endocrinology 145:4575-82. 2004
    ..Although plasma ghrelin levels fall in response to hyperphagic feeding, these findings support the hypothesis that increased ghrelin signaling contributes to the pathogenesis of diabetic hyperphagia...
  16. ncbi request reprint Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia
    Kevin D Niswender
    Division of Metabolism, Endocrinology and Nutrition, University of Washington School of Medicine and Harborview Medical Center, Seattle 98104, USA
    Diabetes 52:227-31. 2003
    ....

Research Grants2

  1. Hypothalamic Leptin and Insulin Signaling
    Christopher Morrison; Fiscal Year: 2007
    ..Therefore, a clear understanding of the cellular signaling events impacting both insulin and leptin signaling within brain areas necessary for their action is of significant scientific and clinical importance. ..
  2. Neural regulation of protein ingestion
    Christopher D Morrison; Fiscal Year: 2010
    ....