Gerlinda E Hermann

Summary

Affiliation: Pennington Biomedical Research Center
Country: USA

Publications

  1. pmc TNF activates astrocytes and catecholaminergic neurons in the solitary nucleus: implications for autonomic control
    Gerlinda E Hermann
    Laboratory of Autonomic Nervous System, Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    Brain Res 1273:72-82. 2009
  2. pmc Proteinase-activated receptors in the nucleus of the solitary tract: evidence for glial-neural interactions in autonomic control of the stomach
    Gerlinda E Hermann
    Autonomic Neuroscience Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana 70808, USA
    J Neurosci 29:9292-300. 2009
  3. ncbi request reprint TNFalpha-stimulation of cFos-activation of neurons in the solitary nucleus is suppressed by TNFR:Fc adsorbant construct in the dorsal vagal complex
    Gerlinda E Hermann
    Laboratory of Autonomic Neuroscience, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
    Brain Res 976:69-74. 2003
  4. doi request reprint CXCR4 receptors in the dorsal medulla: implications for autonomic dysfunction
    Gerlinda E Hermann
    Pennington Biomedical Research Center, Louisiana State University System, 6400 Perkins Road, Baton Rouge, LA 70808, USA
    Eur J Neurosci 27:855-64. 2008
  5. pmc Co-localization of TRHR1 and LepRb receptors on neurons in the hindbrain of the rat
    Maria J Barnes
    Laboratory of Autonomic Neuroscience, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
    Brain Res 1355:70-85. 2010
  6. ncbi request reprint Tumor necrosis factor potentiates central vagal afferent signaling by modulating ryanodine channels
    Richard C Rogers
    Laboratory of Autonomic Neuroscience, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
    J Neurosci 26:12642-6. 2006
  7. pmc Leptin "gates" thermogenic action of thyrotropin-releasing hormone in the hindbrain
    Richard C Rogers
    Laboratory of Autonomic Neurosciences, Pennington Biomedical Research Center, LSU Systems, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    Brain Res 1295:135-41. 2009
  8. pmc Mechanisms of action of CCK to activate central vagal afferent terminals
    Richard C Rogers
    Laboratory of Autonomic Neurosciences, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Peptides 29:1716-25. 2008
  9. pmc Vagal afferent stimulation activates astrocytes in the nucleus of the solitary tract via AMPA receptors: evidence of an atypical neural-glial interaction in the brainstem
    David H McDougal
    Laboratory of Autonomic Neurosciences, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
    J Neurosci 31:14037-45. 2011
  10. pmc Alpha-1 adrenergic input to solitary nucleus neurones: calcium oscillations, excitation and gastric reflex control
    Gerlinda E Hermann
    Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
    J Physiol 562:553-68. 2005

Collaborators

Detail Information

Publications23

  1. pmc TNF activates astrocytes and catecholaminergic neurons in the solitary nucleus: implications for autonomic control
    Gerlinda E Hermann
    Laboratory of Autonomic Nervous System, Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    Brain Res 1273:72-82. 2009
    ....
  2. pmc Proteinase-activated receptors in the nucleus of the solitary tract: evidence for glial-neural interactions in autonomic control of the stomach
    Gerlinda E Hermann
    Autonomic Neuroscience Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana 70808, USA
    J Neurosci 29:9292-300. 2009
    ..g., NST) neurons. These results show, for the first time, that changes in autonomic control can be directly signaled by glial detection of local chemical stimuli...
  3. ncbi request reprint TNFalpha-stimulation of cFos-activation of neurons in the solitary nucleus is suppressed by TNFR:Fc adsorbant construct in the dorsal vagal complex
    Gerlinda E Hermann
    Laboratory of Autonomic Neuroscience, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
    Brain Res 976:69-74. 2003
    ..These results validate our hypothesis that circulating TNF(alpha) may act directly within the DVC to affect gastric function in a variety of pathophysiological states...
  4. doi request reprint CXCR4 receptors in the dorsal medulla: implications for autonomic dysfunction
    Gerlinda E Hermann
    Pennington Biomedical Research Center, Louisiana State University System, 6400 Perkins Road, Baton Rouge, LA 70808, USA
    Eur J Neurosci 27:855-64. 2008
    ..These results suggest that this chemokine receptor may contribute to autonomically mediated pathophysiological events associated with CNS metastasis and infection...
  5. pmc Co-localization of TRHR1 and LepRb receptors on neurons in the hindbrain of the rat
    Maria J Barnes
    Laboratory of Autonomic Neuroscience, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
    Brain Res 1355:70-85. 2010
    ..These anatomical arrangements may provide a basis for the synergy between leptin and TRH to increase thermogenesis...
  6. ncbi request reprint Tumor necrosis factor potentiates central vagal afferent signaling by modulating ryanodine channels
    Richard C Rogers
    Laboratory of Autonomic Neuroscience, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
    J Neurosci 26:12642-6. 2006
    ..Such a scheme may explain how TNF sensitizes visceral as well as somatosensory primary afferents...
  7. pmc Leptin "gates" thermogenic action of thyrotropin-releasing hormone in the hindbrain
    Richard C Rogers
    Laboratory of Autonomic Neurosciences, Pennington Biomedical Research Center, LSU Systems, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    Brain Res 1295:135-41. 2009
    ..Perhaps leptin "gates" the thermogenic action of TRH in the hindbrain by invoking this same mechanism...
  8. pmc Mechanisms of action of CCK to activate central vagal afferent terminals
    Richard C Rogers
    Laboratory of Autonomic Neurosciences, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Peptides 29:1716-25. 2008
    ..Thus, imaging of the isolated but spatially intact hindbrain slice has allowed a more complete appreciation of the interdependent transduction mechanisms used by CCK to excite identified central vagal afferent fibers and varicosities...
  9. pmc Vagal afferent stimulation activates astrocytes in the nucleus of the solitary tract via AMPA receptors: evidence of an atypical neural-glial interaction in the brainstem
    David H McDougal
    Laboratory of Autonomic Neurosciences, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
    J Neurosci 31:14037-45. 2011
    ..These observations suggest that NST astrocytes may be active participants in the regulation of autonomic reflexes even in the normal, healthy state...
  10. pmc Alpha-1 adrenergic input to solitary nucleus neurones: calcium oscillations, excitation and gastric reflex control
    Gerlinda E Hermann
    Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
    J Physiol 562:553-68. 2005
    ..An increase in gain of afferent input may cause an amplification of the response part of the reflex and help explain the powerful effects that alpha-1 agonists have in suppressing gastric motility and producing anorexia...
  11. pmc CXCL12 sensitizes vago-vagal reflex neurons in the dorsal medulla
    Richard C Rogers
    Autonomic Neuroscience Laboratory, Pennington Biomedical Research Center, Louisiana State University System, 6400 Perkins Rd, Baton Rouge, LA 70808, United States
    Brain Res 1492:46-52. 2013
    ....
  12. pmc Tumor necrosis factor activation of vagal afferent terminal calcium is blocked by cannabinoids
    Richard C Rogers
    Laboratory of Autonomic Neuroscience, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
    J Neurosci 32:5237-41. 2012
    ..These results help to explain the effectiveness of cannabinoids in blocking the malaise generated by TNF-releasing disease processes by opposing effects on ryanodine channels...
  13. pmc Leptin amplifies the action of thyrotropin-releasing hormone in the solitary nucleus: an in vitro calcium imaging study
    Richard C Rogers
    Laboratory of Autonomic Neurosciences, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Brain Res 1385:47-55. 2011
    ..It seems likely that NST neurons are involved in the leptin-mediated increase in BAT temperature by sensitizing the TRH-PLC-IP3-calcium release mechanism...
  14. doi request reprint Astrocytes in the hindbrain detect glucoprivation and regulate gastric motility
    David H McDougal
    Laboratory for Autonomic Neuroscience, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
    Auton Neurosci 175:61-9. 2013
    ..Astrocyte inactivation with fluorocitrate blocks the pro-motility effects of glucoprivation. Thus, it appears that intact astrocyte signaling may be essential to glucoregulatory control over gastric motility...
  15. ncbi request reprint TNF alpha-p55 receptors: medullary brainstem immunocytochemical localization in normal and vagus nerve-transected rats
    Gerlinda E Hermann
    Laboratory of Autonomic Neuroscience, Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    Brain Res 1004:156-66. 2004
    ..This increase in p55-ir in axotomized neurons may play a pivotal role in the connection between the occurrence of the injury and the initiation of apoptotic processes resulting in elimination of damaged neurons...
  16. ncbi request reprint Immunocytochemical localization of TNF type 1 and type 2 receptors in the rat spinal cord
    Gregory M Holmes
    Laboratory of Autonomic Neuroscience, Pennington Biomedical Research Center, 6400 Perkins Road, Louisiana State University, Baton Rouge, LA 70808, USA
    Brain Res 1025:210-9. 2004
    ..The presence of TNFR1 receptors, and perhaps their long-term activation or plasticity, may also play a critical role in the chronic allodynia and hyperreflexia observed after SCI or peripheral nerve damage...
  17. pmc Esophageal-gastric relaxation reflex in rat: dual control of peripheral nitrergic and cholinergic transmission
    Gerlinda E Hermann
    Department of Neuroscience, Pennington Biomedical Research Center Louisiana State University System, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    Am J Physiol Regul Integr Comp Physiol 290:R1570-6. 2006
    ..9+/-9.5%. Our data provide a clear demonstration that the gastroinhibitory control by the esophagus is mediated via a dual vagal innervation consisting of inhibitory nitrergic and excitatory cholinergic transmission...
  18. pmc Systemic cholecystokinin amplifies vago-vagal reflex responses recorded in vagal motor neurones
    Edouard Viard
    Pennington Biomedical Research Centre, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    J Physiol 590:631-46. 2012
    ..Thus, our results are in stark contrast to recent reports which have suggested that vago-vagal reflexes are inverted by the metabolic status of the animal and that this inversion could be mediated by CCK within the CNS...
  19. ncbi request reprint Live-cell imaging methods for the study of vagal afferents within the nucleus of the solitary tract
    Richard C Rogers
    Laboratory of Autonomic Neuroscience, Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
    J Neurosci Methods 150:47-58. 2006
    ..Image and preparation stability are a challenge to the success of the experiment; however, methods described here should assist direct studies of transduction events within other afferent terminal fields in the CNS...
  20. pmc Brainstem circuits regulating gastric function
    R Alberto Travagli
    Department of Neuroscience, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana 70808, USA
    Annu Rev Physiol 68:279-305. 2006
    ..e., how neurotransmitters, hormones, and vagal afferent traffic can make an otherwise static autonomic reflex highly plastic...
  21. ncbi request reprint TNFalpha: a trigger of autonomic dysfunction
    Gerlinda E Hermann
    Laboratory of Autonomic Neurosciences, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
    Neuroscientist 14:53-67. 2008
    ..The constitutive presence of TNF alpha receptors on these afferents and their ability to amplify afferent signals may explain how TNF alpha can completely disrupt autonomic control of the gut...
  22. ncbi request reprint Leptin and thyrotropin-releasing hormone: cooperative action in the hindbrain to activate brown adipose thermogenesis
    Gerlinda E Hermann
    Pennington Biomedical Research Center, Louisiana State University System, 6400 Perkins Rd, Baton Rouge, Louisiana 70808, USA
    Brain Res 1117:118-24. 2006
    ..5 degrees C). This effect is undiminished in the acute decerebrate rat, suggesting that the effect is mediated entirely by the hindbrain...
  23. ncbi request reprint LPS-induced suppression of gastric motility relieved by TNFR:Fc construct in dorsal vagal complex
    Gerlinda E Hermann
    Laboratory of Autonomic Neuroscience, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
    Am J Physiol Gastrointest Liver Physiol 283:G634-9. 2002
    ..These results validate our previous studies that suggest that circulating TNF-alpha may act directly within the DVC to affect gastric function in a variety of pathophysiological states...