A E Pekary

Summary

Country: USA

Publications

  1. ncbi request reprint TRH-like antidepressant peptide, pyroglutamyltyroslyprolineamide, occurs in rat brain
    A Eugene Pekary
    Research Service, VA Greater Los Angeles Healthcare System and Department of Medicine, University of California, Los Angeles, CA 90073, USA
    J Mass Spectrom 40:1232-6. 2005
  2. ncbi request reprint Valproate and copper accelerate TRH-like peptide synthesis in male rat pancreas and reproductive tissues
    A E Pekary
    Research Services, VA Greater Los Angeles Healthcare System, University of California, Los Angeles, CA 90073, USA
    Peptides 27:2901-11. 2006
  3. ncbi request reprint Rapid modulation of TRH-like peptides in rat brain by thyroid hormones
    A Eugene Pekary
    Research Service, VA Greater Los Angeles Healthcare System, University of California, Bldg 114, Rm 229, 11301 Wilshire Blvd, Los Angeles, CA 90073, USA
    Peptides 27:1577-88. 2006
  4. ncbi request reprint Rapid modulation of TRH and TRH-like peptide levels in rat brain and peripheral tissues by corticosterone
    A E Pekary
    Research Services, VA Greater Los Angeles Healthcare System, Building 114, Room 229, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
    Neurochem Int 48:208-17. 2006
  5. ncbi request reprint Electroconvulsive seizures increase levels of pGlu-Glu-Pro-NH2 (EEP) in rat brain
    A E Pekary
    Research Service, West Los Angeles VA Medical Center, Department of Medicine, UCLA School of Medicine, CA 90073, USA
    Peptides 20:107-19. 1999
  6. ncbi request reprint Regulation of TRH and TRH-related peptides in rat brain by thyroid and steroid hormones
    A E Pekary
    Research Services, VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Los Angeles, CA 90073, USA
    Peptides 22:1161-73. 2001
  7. ncbi request reprint TRH and related peptides: homeostatic regulators of glutamate transmission?
    A Sattin
    Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, California 90073, USA
    Ann N Y Acad Sci 1003:458-60. 2003
  8. doi request reprint Rapid modulation of TRH and TRH-like peptide release in rat brain and peripheral tissues by leptin
    A E Pekary
    Research Service, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Brain Res 1345:9-18. 2010
  9. ncbi request reprint Electroconvulsive seizures modulate levels of thyrotropin releasing hormone and related peptides in rat hypothalamus, cingulate and lateral cerebellum
    A E Pekary
    Research, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Brain Res 884:174-83. 2000
  10. ncbi request reprint Lithium modulates expression of TRH receptors and TRH-related peptides in rat brain
    A Sattin
    Research Service, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Neuroscience 115:263-73. 2002

Collaborators

Detail Information

Publications12

  1. ncbi request reprint TRH-like antidepressant peptide, pyroglutamyltyroslyprolineamide, occurs in rat brain
    A Eugene Pekary
    Research Service, VA Greater Los Angeles Healthcare System and Department of Medicine, University of California, Los Angeles, CA 90073, USA
    J Mass Spectrom 40:1232-6. 2005
    ..Furthermore, synthetic Tyr-TRH is active in the Porsolt Swim Test suggesting that it is a fourth member of this family of in vivo neuroregulatory agents that have psychopharmacotherapeutic properties...
  2. ncbi request reprint Valproate and copper accelerate TRH-like peptide synthesis in male rat pancreas and reproductive tissues
    A E Pekary
    Research Services, VA Greater Los Angeles Healthcare System, University of California, Los Angeles, CA 90073, USA
    Peptides 27:2901-11. 2006
    ....
  3. ncbi request reprint Rapid modulation of TRH-like peptides in rat brain by thyroid hormones
    A Eugene Pekary
    Research Service, VA Greater Los Angeles Healthcare System, University of California, Bldg 114, Rm 229, 11301 Wilshire Blvd, Los Angeles, CA 90073, USA
    Peptides 27:1577-88. 2006
    ..We conclude that non-genomic mechanisms may contribute to the psychiatric effects of thyroid disease and thyroid hormone adjuvant treatment for major depression...
  4. ncbi request reprint Rapid modulation of TRH and TRH-like peptide levels in rat brain and peripheral tissues by corticosterone
    A E Pekary
    Research Services, VA Greater Los Angeles Healthcare System, Building 114, Room 229, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
    Neurochem Int 48:208-17. 2006
    ..The 4h needed to detect a highly significant change in the TRH and TRH-like peptide levels in brain and peripheral tissues is consistent with the mediation of most corticosterone-effects via alterations in gene transcription...
  5. ncbi request reprint Electroconvulsive seizures increase levels of pGlu-Glu-Pro-NH2 (EEP) in rat brain
    A E Pekary
    Research Service, West Los Angeles VA Medical Center, Department of Medicine, UCLA School of Medicine, CA 90073, USA
    Peptides 20:107-19. 1999
    ....
  6. ncbi request reprint Regulation of TRH and TRH-related peptides in rat brain by thyroid and steroid hormones
    A E Pekary
    Research Services, VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Los Angeles, CA 90073, USA
    Peptides 22:1161-73. 2001
    ..This is the first report that thyroid and steroid hormones alter the levels of TRH, prepro-TRH-derived peptides, and a newly discovered array of TRH-like neuropeptides in limbic brain regions...
  7. ncbi request reprint TRH and related peptides: homeostatic regulators of glutamate transmission?
    A Sattin
    Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, California 90073, USA
    Ann N Y Acad Sci 1003:458-60. 2003
  8. doi request reprint Rapid modulation of TRH and TRH-like peptide release in rat brain and peripheral tissues by leptin
    A E Pekary
    Research Service, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Brain Res 1345:9-18. 2010
    ....
  9. ncbi request reprint Electroconvulsive seizures modulate levels of thyrotropin releasing hormone and related peptides in rat hypothalamus, cingulate and lateral cerebellum
    A E Pekary
    Research, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Brain Res 884:174-83. 2000
    ..Such effects have not previously been reported in these limbic and extra-limbic regions which are increasingly implicated in the autonomic, behavioral and volitional changes which accompany severe depression and its treatment...
  10. ncbi request reprint Lithium modulates expression of TRH receptors and TRH-related peptides in rat brain
    A Sattin
    Research Service, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Neuroscience 115:263-73. 2002
    ..The present results are consistent with a component role for TRH and related peptides in the mood-altering effects of lithium administration and withdrawal frequently observed during treatment for depression and bipolar disorder...
  11. doi request reprint Increased TRH and TRH-like peptide release in rat brain and peripheral tissues during proestrus/estrus
    A E Pekary
    Research Service, VA Greater Los Angeles Healthcare System, United States Center for Ulcer Research and Education, VA Greater Los Angeles Healthcare System, United States Department of Medicine, University of California, Los Angeles, CA 90073, United States Electronic address
    Peptides 52:1-10. 2014
    ..We conclude that these peptides may be downstream mediators of some of the therapeutic effects of estrogen. ..
  12. ncbi request reprint Cocaine regulates TRH-related peptides in rat brain
    A Eugene Pekary
    Research Services, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
    Neurochem Int 41:415-28. 2002
    ..Because TRH and TRH-like peptides have antidepressant, analeptic and euphorigenic properties, we conclude that these endogenous substances are potential mediators of both the cocaine "high" and withdrawal symptoms...