M M Shi

Summary

Affiliation: Parke-Davis Pharmaceutical Research
Country: USA

Publications

  1. ncbi request reprint High-throughput genotyping method for glutathione S-transferase T1 and M1 gene deletions using TaqMan probes
    M M Shi
    Department of Pathology and Experimental Toxicology, Parke Davis Pharmaceutical Research, Warner Lambert Company, Ann Arbor, MI 48105, USA
    Res Commun Mol Pathol Pharmacol 103:3-15. 1999
  2. ncbi request reprint Technologies for detecting genetic polymorphisms in pharmacogenomics
    M M Shi
    Genomic Pathology Laboratory, Pathology and Experimental Toxicology, Parke Davis Pharmaceutical Research, Warner Lambert Company, Ann Arbor, Michigan 48105, USA
    Mol Diagn 4:343-51. 1999
  3. pmc High throughput genotyping for the detection of a single nucleotide polymorphism in NAD(P)H quinone oxidoreductase (DT diaphorase) using TaqMan probes
    M M Shi
    Genomic Pathology Laboratory, Parke Davis Pharmaceutical Research, Warner Lambert Company, Ann Arbor, MI 48105, USA
    Mol Pathol 52:295-9. 1999
  4. ncbi request reprint Pharmacogenetic application in drug development and clinical trials
    M M Shi
    Genomic Pathology Laboratory, Drug Safety Evaluation, Pfizer Global Research and Development, Ann Arbor, Michigan, USA
    Drug Metab Dispos 29:591-5. 2001

Detail Information

Publications4

  1. ncbi request reprint High-throughput genotyping method for glutathione S-transferase T1 and M1 gene deletions using TaqMan probes
    M M Shi
    Department of Pathology and Experimental Toxicology, Parke Davis Pharmaceutical Research, Warner Lambert Company, Ann Arbor, MI 48105, USA
    Res Commun Mol Pathol Pharmacol 103:3-15. 1999
    ..5% and 40.8% for GSTT1 and GSTM1, respectively. This TaqMan genotyping method is rapid, reproducible, and highly sensitive and could be applied toward fully automated large-scale genotyping...
  2. ncbi request reprint Technologies for detecting genetic polymorphisms in pharmacogenomics
    M M Shi
    Genomic Pathology Laboratory, Pathology and Experimental Toxicology, Parke Davis Pharmaceutical Research, Warner Lambert Company, Ann Arbor, Michigan 48105, USA
    Mol Diagn 4:343-51. 1999
    ..Pharmacogenomics is an emerging scientific discipline examining the genetic basis for individual variations in response to therapeutics...
  3. pmc High throughput genotyping for the detection of a single nucleotide polymorphism in NAD(P)H quinone oxidoreductase (DT diaphorase) using TaqMan probes
    M M Shi
    Genomic Pathology Laboratory, Parke Davis Pharmaceutical Research, Warner Lambert Company, Ann Arbor, MI 48105, USA
    Mol Pathol 52:295-9. 1999
    ..The aim of this study was to develop a rapid genotyping procedure for epidemiological and clinical research into the potential biological and toxicological implications associated with this genetic polymorphism...
  4. ncbi request reprint Pharmacogenetic application in drug development and clinical trials
    M M Shi
    Genomic Pathology Laboratory, Drug Safety Evaluation, Pfizer Global Research and Development, Ann Arbor, Michigan, USA
    Drug Metab Dispos 29:591-5. 2001
    ..Pharmacogenetics, thus, impacts all phases of drug development and will fundamentally change the practice of medicine in the near future...