Laxmaiah Manchikanti

Summary

Affiliation: Pain Management Center of Paducah
Country: USA

Publications

  1. ncbi A critical review of the American Pain Society clinical practice guidelines for interventional techniques: part 1. Diagnostic interventions
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E141-74. 2010
  2. ncbi Evaluation of the effectiveness of lumbar interlaminar epidural injections in managing chronic pain of lumbar disc herniation or radiculitis: a randomized, double-blind, controlled trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:343-55. 2010
  3. ncbi A critical review of the American Pain Society clinical practice guidelines for interventional techniques: part 2. Therapeutic interventions
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E215-64. 2010
  4. ncbi Cervical epidural injections in chronic discogenic neck pain without disc herniation or radiculitis: preliminary results of a randomized, double-blind, controlled trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E265-78. 2010
  5. ncbi Preliminary results of a randomized, double-blind, controlled trial of fluoroscopic lumbar interlaminar epidural injections in managing chronic lumbar discogenic pain without disc herniation or radiculitis
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY and Millennium Pain Center, Bloomington, IL, USA
    Pain Physician 13:E279-92. 2010
  6. ncbi Lessons learned in the abuse of pain-relief medication: a focus on healthcare costs
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Expert Rev Neurother 13:527-44. 2013
  7. ncbi A prospective evaluation of psychotherapeutic and illicit drug use in patients presenting with chronic pain at the time of initial evaluation
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 16:E1-E13. 2013
  8. ncbi Growth of spinal interventional pain management techniques: analysis of utilization trends and medicare expenditures 2000 to 2008
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY Anesthesiology and Perioperative Medicine, University of Louisville, Louisville, KY Mid Atlantic Spine and Pain Physicians of Newark, Newark, DE Temple University Hospital, Philadelphia, PA and Departments of Radiology and Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA
    Spine (Phila Pa 1976) 38:157-68. 2013
  9. ncbi Ready or not! Here comes ICD-10
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, Kentucky 42003, USA
    J Neurointerv Surg 5:86-91. 2013
  10. ncbi Fluoroscopic caudal epidural injections in managing post lumbar surgery syndrome: two-year results of a randomized, double-blind, active-control trial
    Laxmaiah Manchikanti
    University of Louisville, Louisville, Kentucky, USA
    Int J Med Sci 9:582-91. 2012

Detail Information

Publications141 found, 100 shown here

  1. ncbi A critical review of the American Pain Society clinical practice guidelines for interventional techniques: part 1. Diagnostic interventions
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E141-74. 2010
    ..However, these guidelines have been questioned regarding their development process, their implementation, and their impact on various specialties...
  2. ncbi Evaluation of the effectiveness of lumbar interlaminar epidural injections in managing chronic pain of lumbar disc herniation or radiculitis: a randomized, double-blind, controlled trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:343-55. 2010
    ..2% to 43%. Among the numerous non-surgical interventions available, epidural injections are the most commonly performed interventions in the United States in managing chronic low back and lower extremity pain...
  3. ncbi A critical review of the American Pain Society clinical practice guidelines for interventional techniques: part 2. Therapeutic interventions
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E215-64. 2010
    ..The recent development of American Pain Society (APS) guidelines has created substantial controversy because of their perceived lack of objective analysis and recommendations perceived to be biased due to conflicts of interest...
  4. ncbi Cervical epidural injections in chronic discogenic neck pain without disc herniation or radiculitis: preliminary results of a randomized, double-blind, controlled trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E265-78. 2010
    ..Despite limited evidence, cervical epidural injections are one of the commonly performed non-surgical interventions in the management of chronic neck pain...
  5. ncbi Preliminary results of a randomized, double-blind, controlled trial of fluoroscopic lumbar interlaminar epidural injections in managing chronic lumbar discogenic pain without disc herniation or radiculitis
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY and Millennium Pain Center, Bloomington, IL, USA
    Pain Physician 13:E279-92. 2010
    ..However, little evidence exists regarding the effectiveness, indications, and medical necessity of lumbar epidural injections in managing axial low back pain without disc herniation or radiculitis...
  6. ncbi Lessons learned in the abuse of pain-relief medication: a focus on healthcare costs
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Expert Rev Neurother 13:527-44. 2013
    ..This manuscript describes the lessons learned from the misuse, abuse and diversion of opioids, escalating healthcare costs and the means to control this epidemic...
  7. ncbi A prospective evaluation of psychotherapeutic and illicit drug use in patients presenting with chronic pain at the time of initial evaluation
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 16:E1-E13. 2013
    ..In the majority of cases, pain physicians have been portrayed as the perpetrators responsible for escalating use and abuse and resultant fatalities...
  8. ncbi Growth of spinal interventional pain management techniques: analysis of utilization trends and medicare expenditures 2000 to 2008
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY Anesthesiology and Perioperative Medicine, University of Louisville, Louisville, KY Mid Atlantic Spine and Pain Physicians of Newark, Newark, DE Temple University Hospital, Philadelphia, PA and Departments of Radiology and Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA
    Spine (Phila Pa 1976) 38:157-68. 2013
    ..8%, an annual average increase of 14.1% per 100,000 beneficiaries. CONCLUSION.: The study suggests explosive increases in spinal interventional techniques from 2000 to 2008, with some slowing of growth in later years...
  9. ncbi Ready or not! Here comes ICD-10
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, Kentucky 42003, USA
    J Neurointerv Surg 5:86-91. 2013
    ..The estimated cost per physician is projected to range from $25 000 to $50 000...
  10. ncbi Fluoroscopic caudal epidural injections in managing post lumbar surgery syndrome: two-year results of a randomized, double-blind, active-control trial
    Laxmaiah Manchikanti
    University of Louisville, Louisville, Kentucky, USA
    Int J Med Sci 9:582-91. 2012
    ..Summary of Background Data: There is a paucity of evidence concerning caudal epidural injections for managing chronic persistent low back pain with or without lower extremity pain caused by post lumbar surgery syndrome...
  11. ncbi Proposed physician payment schedule for 2013: guarded prognosis for interventional pain management
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 15:E615-27. 2012
    ..In this manuscript, we will describe important proposed changes to the physician fee schedule. Additionally, the impact of multiple changes on interventional pain management will be briefly described...
  12. ncbi Results of 2-year follow-up of a randomized, double-blind, controlled trial of fluoroscopic caudal epidural injections in central spinal stenosis
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 15:371-84. 2012
    ..However, there is a paucity of literature from randomized, controlled trials about the effectiveness of epidural injections for lumbar central spinal stenosis...
  13. ncbi Obamacare 2012: prognosis unclear for interventional pain management
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 15:E629-40. 2012
    ....
  14. ncbi Pain in patients with chronic fatigue syndrome: time for specific pain treatment?
    Jo Nijs
    Chronic Pain and Chronic Fatigue Research Group, Department of Human Physiology, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussels, Belgium
    Pain Physician 15:E677-86. 2012
    ..Besides chronic fatigue, patients with chronic fatigue syndrome (CFS) have debilitating widespread pain. Yet pain from CFS is often ignored by clinicians and researchers...
  15. ncbi Comparative evaluation of the accuracy of immunoassay with liquid chromatography tandem mass spectrometry (LC/MS/MS) of urine drug testing (UDT) opioids and illicit drugs in chronic pain patients
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:175-87. 2011
    ..However, significant controversy surrounds the diagnostic accuracy of UDT performed in the office (immunoassay) and the requirement for laboratory confirmation with liquid chromatography tandem mass spectrometry (LC/MS/MS)...
  16. ncbi The Independent Payment Advisory Board
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, Kentucky, USA
    Pain Physician 14:E313-42. 2011
    ....
  17. ncbi Prevalence of side effects of prolonged low or moderate dose opioid therapy with concomitant benzodiazepine and/or antidepressant therapy in chronic non-cancer pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:259-67. 2009
    ..However, there is no data available on the prevalence of side effects associated with low or moderate dose opioid use in chronic non-cancer pain when administered in conjunction with interventional techniques...
  18. ncbi Description of documentation in the management of chronic spinal pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:E199-224. 2009
    ..With minor variations, these requirements are similar for an in-office setting, hospital out patient department, and ambulatory surgery centers...
  19. ncbi Breakthrough pain in chronic non-cancer pain: fact, fiction, or abuse
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:E103-17. 2011
    ..This comprehensive review critically evaluates the available evidence of breakthrough pain in chronic non-cancer pain including its existence, prevalence, and managing symptoms which are described as breakthrough pain or episodic pain...
  20. ncbi Medicare physician payment systems: impact of 2011 schedule on interventional pain management
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:E5-33. 2011
    ..Consequently, CMS issued an emergency update of the 2011 Medicare fee schedule, with multiple revisions, resulting in a reduction of the conversion factor of $36.8729 from December 2010 to $33.9764 for 2011...
  21. ncbi Evaluation of lumbar facet joint nerve blocks in managing chronic low back pain: a randomized, double-blind, controlled trial with a 2-year follow-up
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Int J Med Sci 7:124-35. 2010
    ..A randomized, double-blind, controlled trial...
  22. ncbi Facts, fallacies, and politics of comparative effectiveness research: Part 2 - implications for interventional pain management
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E55-79. 2010
    ....
  23. ncbi Effect of fluoroscopically guided caudal epidural steroid or local anesthetic injections in the treatment of lumbar disc herniation and radiculitis: a randomized, controlled, double blind trial with a two-year follow-up
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 15:273-86. 2012
    ....
  24. ncbi Opioid epidemic in the United States
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 15:ES9-38. 2012
    ..The obstacles that must be surmounted are primarily inappropriate prescribing patterns, which are largely based on a lack of knowledge, perceived safety, and inaccurate belief of undertreatment of pain...
  25. ncbi Fluoroscopic caudal epidural injections with or without steroids in managing pain of lumbar spinal stenosis: one-year results of randomized, double-blind, active-controlled trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    J Spinal Disord Tech 25:226-34. 2012
    ..A randomized, double-blind, active-controlled trial...
  26. ncbi Effectiveness of therapeutic lumbar transforaminal epidural steroid injections in managing lumbar spinal pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 15:E199-245. 2012
    ..However, there are only a few well-designed, randomized, controlled studies on the effectiveness of steroid injections. Consequently, multiple systematic reviews with diverse opinions have been published...
  27. ncbi A prospective evaluation of complications of 10,000 fluoroscopically directed epidural injections
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, 2831 Lone Oak Road, Paducah, KY 42003, USA
    Pain Physician 15:131-40. 2012
    ..Thus, prospective studies with large patient series are essential to determine the types and incidences of complications...
  28. ncbi Saga of payment systems of ambulatory surgery centers for interventional techniques: an update
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, 2831 Lone Oak Road, Paducah, KY 42003, USA
    Pain Physician 15:109-30. 2012
    ....
  29. ncbi Patient Protection and Affordable Care Act of 2010: a primer for neurointerventionalists
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    J Neurointerv Surg 4:141-6. 2012
    ..The ACA goes well beyond insurance and payment reform. Practicing physicians will potentially be impacted by the Independent Payment Advisory Board and the Patient Centered Outcomes Research Institute...
  30. ncbi Fluoroscopic cervical interlaminar epidural injections in managing chronic pain of cervical postsurgery syndrome: preliminary results of a randomized, double-blind, active control trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 15:13-25. 2012
    ..However there have not been any systematic evaluations regarding the effectiveness of cervical epidural injections in cervical postsurgery syndrome...
  31. ncbi Lumbar interlaminar epidural injections in central spinal stenosis: preliminary results of a randomized, double-blind, active control trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah Paducah, KY, USA
    Pain Physician 15:51-63. 2012
    ..However, there is little in the medical literature to support interlaminar, or transforaminal epidural injections under fluoroscopy for managing lumbar pain of central spinal stenosis, while the caudal epidural approach has been studied...
  32. ncbi Guidelines warfare over interventional techniques: is there a lack of discourse or straw man?
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 15:E1-E26. 2012
    ..Further, this review will attempt to demonstrate that excessive focus on this straw man has inhibited critique of what we believe to be flaws in the approach.  ..
  33. ncbi Physician payment outlook for 2012: déjà vu
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 15:E27-52. 2012
    ..Interventional pain management, like other evolving specialties will probably most likely suffer under the new affordable health care law and regulatory burden...
  34. ncbi Fluoroscopic epidural injections in cervical spinal stenosis: preliminary results of a randomized, double-blind, active control trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 15:E59-70. 2012
    ..Emerging evidence for cervical interlaminar epidurals for various conditions in the cervical spine is positive; however, the effect of fluoroscopic epidural injections in cervical spinal stenosis has not been studied...
  35. ncbi Comprehensive evidence-based guidelines for interventional techniques in the management of chronic spinal pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:699-802. 2009
    ..Comprehensive, evidence-based guidelines for interventional techniques in the management of chronic spinal pain are described here to provide recommendations for clinicians...
  36. ncbi Systematic review of lumbar discography as a diagnostic test for chronic low back pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:541-59. 2009
    ..Despite the extensive literature, controversy continues about provocation lumbar discography...
  37. ncbi Making sense of the accuracy of diagnostic lumbar facet joint nerve blocks: an assessment of the implications of 50% relief, 80% relief, single block, or controlled diagnostic blocks
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:133-43. 2010
    ..However, controversy surrounds the following related issues: placebo control, the amount of relief (50% versus 80%), single block versus double block, and placebo or comparative control...
  38. ncbi Evidence-based medicine, systematic reviews, and guidelines in interventional pain management: part 5. Diagnostic accuracy studies
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:517-40. 2009
    ..Part 5 of evidence-based medicine (EBM) in interventional pain management describes the various aspects of diagnostic accuracy studies...
  39. ncbi Protocol for evaluation of the comparative effectiveness of percutaneous adhesiolysis and caudal epidural steroid injections in low back and/or lower extremity pain without post surgery syndrome or spinal stenosis
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E91-E110. 2010
    ....
  40. ncbi Explosive growth of facet joint interventions in the Medicare population in the United States: a comparative evaluation of 1997, 2002, and 2006 data
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, 2831 Lone Oak Road, Paducah, KY, 42003, USA
    BMC Health Serv Res 10:84. 2010
    ..The purpose of the study was to determine trends of frequency and cost of facet joint interventions in managing spinal pain...
  41. ncbi Analysis of the growth of epidural injections and costs in the Medicare population: a comparative evaluation of 1997, 2002, and 2006 data
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:199-212. 2010
    ..However, an analysis of the growth of epidural injections and costs in the Medicare population has not been performed with recent data and has not been looked at from an interventional pain management perspective...
  42. ncbi The effectiveness of fluoroscopic cervical interlaminar epidural injections in managing chronic cervical disc herniation and radiculitis: preliminary results of a randomized, double-blind, controlled trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:223-36. 2010
    ..However, the literature supporting cervical interlaminar epidural steroids in managing chronic neck pain is scant...
  43. ncbi Protocol for accuracy of point of care (POC) or in-office urine drug testing (immunoassay) in chronic pain patients: a prospective analysis of immunoassay and liquid chromatography tandem mass spectometry (LC/MS/MS)
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E1-E22. 2010
    ..Thus far, there have not been any studies systematically assessing the diagnostic accuracy of immunoassay with laboratory testing...
  44. ncbi A comparative effectiveness evaluation of percutaneous adhesiolysis and epidural steroid injections in managing lumbar post surgery syndrome: a randomized, equivalence controlled trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:E355-68. 2009
    ..However, the evidence for percutaneous adhesiolysis in managing post surgery syndrome has been questioned, coupled with a paucity of controlled trials...
  45. ncbi The preliminary results of a comparative effectiveness evaluation of adhesiolysis and caudal epidural injections in managing chronic low back pain secondary to spinal stenosis: a randomized, equivalence controlled trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:E341-54. 2009
    ..There have not been any randomized trials evaluating the effectiveness of percutaneous adhesiolysis and targeted delivery of local anesthetic, steroid and hypertonic sodium chloride solution in lumbar spinal stenosis...
  46. ncbi Evidence-based medicine, systematic reviews, and guidelines in interventional pain management: part 6. Systematic reviews and meta-analyses of observational studies
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:819-50. 2009
    ..A combined approach of QUOROM and MOOSE will improve reporting of systematic reviews and lead to progress and innovations in health care...
  47. ncbi A systematic review of mechanical lumbar disc decompression with nucleoplasty
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:561-72. 2009
    ..There is a paucity of evidence for all decompression techniques, specifically alternative techniques including nucleoplasty...
  48. ncbi Comprehensive review of neurophysiologic basis and diagnostic interventions in managing chronic spinal pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:E71-120. 2009
    ..In contrast, controlled diagnostic blocks have been shown to determine the cause of pain in as many as 85% of the patients...
  49. ncbi An algorithmic approach for clinical management of chronic spinal pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:E225-64. 2009
    ..In managing thoracic pain, a diagnostic and therapeutic algorithmic approach includes either facet joint interventions or epidural injections...
  50. ncbi Comprehensive review of therapeutic interventions in managing chronic spinal pain
    Laxmaiah Manchikanti
    Pain ManagementCenter of Paducah, Paducah, KY, USA
    Pain Physician 12:E123-98. 2009
    ..Available evidence documents a wide degree of variance in the definition and practice of interventional pain management...
  51. ncbi An introduction to an evidence-based approach to interventional techniques in the management of chronic spinal pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:E1-33. 2009
    ..Evidence synthesis for guidelines includes the review of all relevant systematic reviews and individual articles, grading them for relevance, methodologic quality, consistency, and recommendations...
  52. ncbi Interventional pain management at crossroads: the perfect storm brewing for a new decade of challenges
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E111-40. 2010
    ..This manuscript will analyze various issues related to interventional pain management with a critical analysis of physician payments, office facility payments, and ASC payments by various payor groups...
  53. ncbi Placebo and nocebo in interventional pain management: a friend or a foe--or simply foes?
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:E157-75. 2011
    ..The research setting itself may introduce nocebo hyperalgesia...
  54. ncbi Ambulatory surgery centers and interventional techniques: a look at long-term survival
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:E177-215. 2011
    ..Thus, the landscape of interventional pain management in ambulatory surgery centers has been constantly changing with declining reimbursements, issues of fraud and abuse, and ever-increasing regulations...
  55. ncbi Comparative evaluation of the accuracy of benzodiazepine testing in chronic pain patients utilizing immunoassay with liquid chromatography tandem mass spectrometry (LC/MS/MS) of urine drug testing
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 14:259-70. 2011
    ....
  56. ncbi The impact of comparative effectiveness research on interventional pain management: evolution from Medicare Modernization Act to Patient Protection and Affordable Care Act and the Patient-Centered Outcomes Research Institute
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:E249-82. 2011
    ..Thus, PCORI is operating in an ad hoc manner that is incompatible with the principles of evidence-based practice.This manuscript describes the framework of PCORI, and the role of CER and its impact on interventional pain management...
  57. ncbi Medicare physician payment rules for 2011: a primer for the neurointerventionalist
    L Manchikanti
    Pain Management Center of Paducah, Kentucky 42003, USA
    AJNR Am J Neuroradiol 32:E101-4. 2011
    ..The mechanism of the sustainable growth rate includes three components that are incorporated into a statutory formula: expenditure targets, growth rate period and annual adjustments of payment rates for physician services...
  58. ncbi A randomized, controlled, double-blind trial of fluoroscopic caudal epidural injections in the treatment of lumbar disc herniation and radiculitis
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Spine (Phila Pa 1976) 36:1897-905. 2011
    ..A randomized, controlled, double-blind trial...
  59. ncbi Infection control practices (safe injection and medication vial utilization) for interventional techniques: are they based on relative risk management or evidence?
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:425-34. 2011
    ..Further, the effectiveness or necessity of surgical face masks and hats, etc., for interventional techniques has not been proven...
  60. ncbi Preoperative fasting before interventional techniques: is it necessary or evidence-based?
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY
    Pain Physician 14:459-67. 2011
    ..However, there are no guidelines for interventional techniques for sedation or fasting. Most interventional techniques are performed under intravenous or conscious sedation...
  61. ncbi Effectiveness of long-term opioid therapy for chronic non-cancer pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:E133-56. 2011
    ....
  62. ncbi A prospective evaluation of bleeding risk of interventional techniques in chronic pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:317-29. 2011
    ..However, it has been a common practice to discontinue antiplatelet therapy prior to performing interventional techniques, which may potentially increase the risk of acute cerebral and cardiovascular events...
  63. ncbi A systematic review of randomized trials of long-term opioid management for chronic non-cancer pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:91-121. 2011
    ..Even though evidence is limited, multiple expert panels have concluded that chronic opioid therapy can be effective therapy for carefully selected and monitored patients with chronic non-cancer pain...
  64. ncbi Therapeutic use, abuse, and nonmedical use of opioids: a ten-year perspective
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:401-35. 2010
    ..This manuscript provides an updated 10-year perspective on therapeutic use, abuse, and non-medical use of opioids and their consequences. ..
  65. ncbi Comparative outcomes of a 2-year follow-up of cervical medial branch blocks in management of chronic neck pain: a randomized, double-blind controlled trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, Kentucky, USA
    Pain Physician 13:437-50. 2010
    ..However, the effectiveness of these modalities continues to be debated. The purpose of this study was to determine the clinical effectiveness of therapeutic cervical medial branch blocks with or without steroids...
  66. ncbi Comparative effectiveness of a one-year follow-up of thoracic medial branch blocks in management of chronic thoracic pain: a randomized, double-blind active controlled trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:535-48. 2010
    ..Various therapeutic techniques utilized in managing chronic thoracic pain of facet joint origin include intraarticular injections, medial branch blocks, and radiofrequency neurotomy of thoracic medial branch nerves...
  67. ncbi A preliminary report of a randomized double-blind, active controlled trial of fluoroscopic thoracic interlaminar epidural injections in managing chronic thoracic pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E357-69. 2010
    ..In addition, there is a paucity of literature regarding thoracic intervertebral discs and thoracic disc herniation as causative structures of thoracic pain...
  68. ncbi One-year results of a randomized, double-blind, active controlled trial of fluoroscopic caudal epidural injections with or without steroids in managing chronic discogenic low back pain without disc herniation or radiculitis
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:25-36. 2011
    ..However, there is little evidence utilizing contemporary methodology for using epidural injections in patients with discogenic pain...
  69. ncbi Necessity and implications of ICD-10: facts and fallacies
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, Kentucky, USA
    Pain Physician 14:E405-25. 2011
    ..The authors of this article favor postponing the implementation of the ICD-10 until such time as its necessity is proven and implications are understood.  ..
  70. ncbi Systematic review of cervical discography as a diagnostic test for chronic spinal pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 12:305-21. 2009
    ..Yet in the absence of validation and controlled outcome studies, the procedure remains mired in controversy...
  71. ncbi Obama health care for all Americans: practical implications
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 12:289-304. 2009
    ..Down payment on health care reform, American Recovery and Reinvestment Act, and CHIP include many provisions to reach towards universal health care...
  72. ncbi Reassessment of evidence synthesis of occupational medicine practice guidelines for interventional pain management
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 11:393-482. 2008
    ....
  73. ncbi Cervical medial branch blocks for chronic cervical facet joint pain: a randomized, double-blind, controlled trial with one-year follow-up
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Spine (Phila Pa 1976) 33:1813-20. 2008
    ..A double-blind, randomized, controlled trial...
  74. ncbi Health care reform in the United States: radical surgery needed now more than ever
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 11:13-42. 2008
    ..This manuscript will review escalating national health care expenditures, factors contributing to health care increases, health care systems in many other countries, and various proposals...
  75. ncbi Age-related prevalence of facet-joint involvement in chronic neck and low back pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 11:67-75. 2008
    ..The studies of low back pain have shown the prevalence of facet joint involvement to be approximately 15% to 45%. However, age related prevalence of facet joint neck pain has not been studied...
  76. ncbi Review of occupational medicine practice guidelines for interventional pain management and potential implications
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 11:271-89. 2008
    ....
  77. ncbi Lumbar facet joint nerve blocks in managing chronic facet joint pain: one-year follow-up of a randomized, double-blind controlled trial: Clinical Trial NCT00355914
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 11:121-32. 2008
    ..Various therapeutic techniques including intraarticular injections, medial branch blocks, and radiofrequency neurotomy of lumbar facet joint nerves have been described in the alleviation of chronic low back pain of facet joint origin...
  78. ncbi Influence of psychological variables on the diagnosis of facet joint involvement in chronic spinal pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 11:145-60. 2008
    ..A lack of influence of psychological factors on the validity of controlled diagnostic local anesthetic blocks of lumbar facet joints has been demonstrated. However, no such studies have been performed in the thoracic or cervical spine...
  79. ncbi Therapeutic opioids: a ten-year perspective on the complexities and complications of the escalating use, abuse, and nonmedical use of opioids
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, KY 42003, USA
    Pain Physician 11:S63-88. 2008
    ..Patients on long-term opioid use have been shown to increase the overall cost of healthcare, disability, rates of surgery, and late opioid use...
  80. ncbi Evidence-based medicine, systematic reviews, and guidelines in interventional pain management, part I: introduction and general considerations
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 11:161-86. 2008
    ..Part 1 of this series in evidence-based medicine, systematic reviews, and guidelines in interventional pain management provides an introduction and general considerations of these 3 aspects in interventional pain management...
  81. ncbi Effectiveness of thoracic medial branch blocks in managing chronic pain: a preliminary report of a randomized, double-blind controlled trial
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 11:491-504. 2008
    ..Various therapeutic techniques utilized in managing chronic thoracic pain of facet joint origin include intraarticular injections, medial branch blocks, and radiofrequency neurotomy of thoracic facet joint nerves...
  82. ncbi Monitoring opioid adherence in chronic pain patients: tools, techniques, and utility
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 11:S155-80. 2008
    ....
  83. ncbi Evidence-based medicine, systematic reviews, and guidelines in interventional pain management: part 4: observational studies
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:73-108. 2009
    ....
  84. ncbi Evidence-based medicine, systematic reviews, and guidelines in interventional pain management: part 3: systematic reviews and meta-analyses of randomized trials
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:35-72. 2009
    ..This review describes various aspects of systematic reviews and meta-analyses of randomized trials with a special focus on interventional pain management...
  85. ncbi Analysis of growth of interventional techniques in managing chronic pain in the Medicare population: a 10-year evaluation from 1997 to 2006
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:9-34. 2009
    ..Interventional pain management (IPM) is an evolving specialty amenable to multiple influences. Evaluation and isolation of appropriate factors for increasing growth patterns have not been performed...
  86. ncbi Preliminary results of a randomized, equivalence trial of fluoroscopic caudal epidural injections in managing chronic low back pain: Part 4--Spinal stenosis
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 11:833-48. 2008
    ....
  87. ncbi Preliminary results of a randomized, equivalence trial of fluoroscopic caudal epidural injections in managing chronic low back pain: Part 3--Post surgery syndrome
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 11:817-31. 2008
    ..There is lack of evidence for the effectiveness of epidural injections in managing chronic low back pain with or without lower extremity pain secondary to post surgery syndrome...
  88. ncbi Preliminary results of a randomized, equivalence trial of fluoroscopic caudal epidural injections in managing chronic low back pain: Part 2--Disc herniation and radiculitis
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 11:801-15. 2008
    ..There is a paucity of evidence with contemporary methodology used in performing epidural injections under fluoroscopy and based on pain relief and functional status improvement...
  89. ncbi A critical appraisal of 2007 American College of Occupational and Environmental Medicine (ACOEM) Practice Guidelines for Interventional Pain Management: an independent review utilizing AGREE, AMA, IOM, and other criteria
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 11:291-310. 2008
    ....
  90. ncbi Preliminary results of a randomized, equivalence trial of fluoroscopic caudal epidural injections in managing chronic low back pain: Part 1--Discogenic pain without disc herniation or radiculitis
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 11:785-800. 2008
    ..Even though epidural injections are frequently administered in managing axial low back pain, the evidence is lacking...
  91. ncbi Evidence-based medicine, systematic reviews, and guidelines in interventional pain management: Part 2: Randomized controlled trials
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 11:717-73. 2008
    ....
  92. ncbi Therapeutic cervical medial branch blocks in managing chronic neck pain: a preliminary report of a randomized, double-blind, controlled trial: clinical trial NCT0033272
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 9:333-46. 2006
    ..Intraarticular injections, medial branch nerve blocks and neurolysis of medial branch nerves have been described in managing chronic neck pain of facet joint origin...
  93. ncbi Evaluation of lumbar facet joint nerve blocks in the management of chronic low back pain: preliminary report of a randomized, double-blind controlled trial: clinical trial NCT00355914
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY 42003, USA
    Pain Physician 10:425-40. 2007
    ..Therapeutic interventions utilized in managing chronic low back pain of facet joint origin include intraarticular injections, medial branch nerve blocks, and neurolysis of medial branch nerves...
  94. ncbi Prevalence of facet joint pain in chronic spinal pain of cervical, thoracic, and lumbar regions
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, 2831 Lone Oak Road, Paducah, Kentucky, USA
    BMC Musculoskelet Disord 5:15. 2004
    ..The purpose of this study was to systematically evaluate the prevalence of facet joint pain by spinal region in patients with chronic spine pain referred to an interventional pain management practice...
  95. ncbi Accuracy of diagnostic lumbar facet joint nerve blocks: a 2-year follow-up of 152 patients diagnosed with controlled diagnostic blocks
    Sneha Pampati
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 12:855-66. 2009
    ....
  96. ncbi Psychological factors as predictors of opioid abuse and illicit drug use in chronic pain patients
    Laxmaiah Manchikanti
    Pain Management Center of Paducab, Kentucky, USA
    J Opioid Manag 3:89-100. 2007
    ....
  97. ncbi Influence of prior opioid exposure on diagnostic facet joint nerve blocks
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, Kentucky, USA
    J Opioid Manag 4:351-60. 2008
    ..To determine the influence of prior opioid use on the diagnostic validity of controlled comparative local anesthetic blocks in the diagnosis of facet joint involvement in chronic spinal pain...
  98. ncbi Controlled substance abuse and illicit drug use in chronic pain patients: An evaluation of multiple variables
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, 2831 Lone Oak Road, Paducah, Kentucky 42003, USA
    Pain Physician 9:215-25. 2006
    ..Opioid abuse has been demonstrated in 9% to 41% of patients receiving chronic pain management. Illicit drug use has been reported in 14% to 34% of patients in chronic pain management settings...
  99. ncbi Facts, fallacies, and politics of comparative effectiveness research: Part I. Basic considerations
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 13:E23-54. 2010
    ..Part I of this comprehensive review will describe facts, fallacies, and politics of CER with discussions to understand basic concepts of CER...
  100. ncbi Does random urine drug testing reduce illicit drug use in chronic pain patients receiving opioids?
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Kentucky 42003, USA
    Pain Physician 9:123-9. 2006
    ..Random drug testing for appropriate use of opioids and use of illicit drugs is often used in pain management practices. Thus, it is expected that random urine drug testing will deter use of illicit drugs, and also improve compliance...
  101. ncbi Prevalence of facet joint pain in chronic low back pain in postsurgical patients by controlled comparative local anesthetic blocks
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Arch Phys Med Rehabil 88:449-55. 2007
    ..To evaluate the prevalence of facet joint pain in patients with chronic low back pain (CLBP) after surgical intervention(s)...