John R Cort

Summary

Affiliation: Pacific Northwest National Laboratory
Country: USA

Publications

  1. doi request reprint Structure of an acetyl-CoA binding protein from Staphylococcus aureus representing a novel subfamily of GCN5-related N-acetyltransferase-like proteins
    John R Cort
    Washington State University Tri Cities, Richland, WA 99354, USA
    J Struct Funct Genomics 9:7-20. 2008
  2. doi request reprint 1H, 13C, and 15N backbone, side-chain, and heme chemical shift assignments for oxidized and reduced forms of the monoheme c-type cytochrome ApcA isolated from the acidophilic metal-reducing bacterium Acidiphilium cryptum
    John R Cort
    Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Biomol NMR Assign 5:89-92. 2011
  3. ncbi request reprint Solution NMR structure of the iron-sulfur cluster assembly protein U (IscU) with zinc bound at the active site
    Theresa A Ramelot
    Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    J Mol Biol 344:567-83. 2004
  4. ncbi request reprint NMR structure and binding studies confirm that PA4608 from Pseudomonas aeruginosa is a PilZ domain and a c-di-GMP binding protein
    Theresa A Ramelot
    Pacific Northwest National Laboratory, Biological Sciences Division, Richland, Washington 99354, USA
    Proteins 66:266-71. 2007
  5. ncbi request reprint Solution structure of the yeast ubiquitin-like modifier protein Hub1
    Theresa A Ramelot
    Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    J Struct Funct Genomics 4:25-30. 2003
  6. ncbi request reprint Myxoma virus immunomodulatory protein M156R is a structural mimic of eukaryotic translation initiation factor eIF2alpha
    Theresa A Ramelot
    Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    J Mol Biol 322:943-54. 2002
  7. pmc Allochromatium vinosum DsrC: solution-state NMR structure, redox properties, and interaction with DsrEFH, a protein essential for purple sulfur bacterial sulfur oxidation
    John R Cort
    Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    J Mol Biol 382:692-707. 2008
  8. doi request reprint Counterion influence on chemical shifts in strychnine salts
    Athena E Metaxas
    Fundamental and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Magn Reson Chem 51:292-8. 2013
  9. pmc Top-down proteomics reveals a unique protein S-thiolation switch in Salmonella Typhimurium in response to infection-like conditions
    Charles Ansong
    Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Proc Natl Acad Sci U S A 110:10153-8. 2013
  10. pmc Solution structure of Vibrio cholerae protein VC0424: a variation of the ferredoxin-like fold
    Theresa A Ramelot
    Biological Sciences Division, Pacific Northwest National Laboratory, EMSL 2569 K8 98, 3335 Q Avenue, Richland, WA 99352, USA
    Protein Sci 12:1556-61. 2003

Collaborators

Detail Information

Publications17

  1. doi request reprint Structure of an acetyl-CoA binding protein from Staphylococcus aureus representing a novel subfamily of GCN5-related N-acetyltransferase-like proteins
    John R Cort
    Washington State University Tri Cities, Richland, WA 99354, USA
    J Struct Funct Genomics 9:7-20. 2008
    ....
  2. doi request reprint 1H, 13C, and 15N backbone, side-chain, and heme chemical shift assignments for oxidized and reduced forms of the monoheme c-type cytochrome ApcA isolated from the acidophilic metal-reducing bacterium Acidiphilium cryptum
    John R Cort
    Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Biomol NMR Assign 5:89-92. 2011
    ..We also describe the preparation and purification of the protein in labeled form from laboratory cultures of A. cryptum growing on (13)C- and (15)N- labeled substrates...
  3. ncbi request reprint Solution NMR structure of the iron-sulfur cluster assembly protein U (IscU) with zinc bound at the active site
    Theresa A Ramelot
    Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    J Mol Biol 344:567-83. 2004
    ..e. derived from a common ancestor) with the SufE/YgdK family of [Fe-S] cluster assembly proteins...
  4. ncbi request reprint NMR structure and binding studies confirm that PA4608 from Pseudomonas aeruginosa is a PilZ domain and a c-di-GMP binding protein
    Theresa A Ramelot
    Pacific Northwest National Laboratory, Biological Sciences Division, Richland, Washington 99354, USA
    Proteins 66:266-71. 2007
    ..Chemical shift changes in PA4608 resonances upon titration with c-di-GMP confirm binding. This evidence supports the hypothesis that proteins containing PilZ domains are the long-sought c-di-GMP adaptor proteins...
  5. ncbi request reprint Solution structure of the yeast ubiquitin-like modifier protein Hub1
    Theresa A Ramelot
    Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    J Struct Funct Genomics 4:25-30. 2003
  6. ncbi request reprint Myxoma virus immunomodulatory protein M156R is a structural mimic of eukaryotic translation initiation factor eIF2alpha
    Theresa A Ramelot
    Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    J Mol Biol 322:943-54. 2002
    ....
  7. pmc Allochromatium vinosum DsrC: solution-state NMR structure, redox properties, and interaction with DsrEFH, a protein essential for purple sulfur bacterial sulfur oxidation
    John R Cort
    Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    J Mol Biol 382:692-707. 2008
    ....
  8. doi request reprint Counterion influence on chemical shifts in strychnine salts
    Athena E Metaxas
    Fundamental and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Magn Reson Chem 51:292-8. 2013
    ....
  9. pmc Top-down proteomics reveals a unique protein S-thiolation switch in Salmonella Typhimurium in response to infection-like conditions
    Charles Ansong
    Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Proc Natl Acad Sci U S A 110:10153-8. 2013
    ..The demonstrated utility of our simple proteome-wide intact protein level measurement strategy for gaining biological insight should promote broader adoption and applications of top-down proteomics approaches...
  10. pmc Solution structure of Vibrio cholerae protein VC0424: a variation of the ferredoxin-like fold
    Theresa A Ramelot
    Biological Sciences Division, Pacific Northwest National Laboratory, EMSL 2569 K8 98, 3335 Q Avenue, Richland, WA 99352, USA
    Protein Sci 12:1556-61. 2003
    ..A cluster of conserved surface residues on the beta-sheet side of the protein forms a pocket that may be important for the biological function of this conserved family of proteins...
  11. doi request reprint (1)H and (13)C NMR chemical shift assignments and conformational analysis for the two diastereomers of the vitamin K epoxide reductase inhibitor brodifacoum
    John R Cort
    Fundamental and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    Magn Reson Chem 47:897-901. 2009
    ..These assignments and conformational analyses may be useful in studies of biomolecular interactions of brodifacoum with target proteins such as VKOR and in source determination of brodifacoum...
  12. ncbi request reprint NMR structure of conserved eukaryotic protein ZK652.3 from C. elegans: a ubiquitin-like fold
    John R Cort
    Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    Proteins 48:733-6. 2002
  13. pmc 1H, 13C, and 15N resonance assignments of murine amelogenin, an enamel biomineralization protein
    Garry W Buchko
    Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Biomol NMR Assign 2:89-91. 2008
    ..Making extensive use of residue specific 15N-labeled amino acids samples, the majority of the main and side chain resonances for murine amelogenin were assigned in 2% aqueous acetic acid at pH 3.0...
  14. pmc Mixed-isotope labeling with LC-IMS-MS for characterization of protein-protein interactions by chemical cross-linking
    Eric D Merkley
    Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    J Am Soc Mass Spectrom 24:444-9. 2013
    ..Because of the separation of cross-linked and non-cross-linked peptides in drift time, our LC-IMS-MS approach was able to confidently detect more intermolecular cross-linked peptides than LC-MS alone...
  15. ncbi request reprint NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins
    Theresa A Ramelot
    Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    Proteins 49:289-93. 2002
  16. pmc Cross-linking and mass spectrometry methodologies to facilitate structural biology: finding a path through the maze
    Eric D Merkley
    MS K8 98, Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    J Struct Funct Genomics 14:77-90. 2013
    ..These examples (as well as many others) illustrate the utility of a chemical cross-linking-mass spectrometry approach in facilitating structural analysis of large and challenging complexes. ..
  17. ncbi request reprint Measurement and analysis of diastereomer ratios for forensic characterization of brodifacoum
    John R Cort
    Fundamental and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Forensic Sci Int 214:178-81. 2012
    ..The results reveal detectable source-to-source and batch-to-batch variations in diastereomer ratios...