Research Topics
| Cheryl L BairdSummaryAffiliation: Pacific Northwest National Laboratory Country: USA Publications
| Collaborators
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Detail Information
Publications
Developing recombinant antibodies for biomarker detectionCheryl L Baird
Pacific Northwest National Laboratory, Richland, WA, USA
Cancer Biomark 6:271-9. 2010..Combinatorial protein display also provides an accessible method for identifying antibody pairs, which are necessary for sandwich-type diagnostic assays...
Reducing heterophilic antibody interference in immunoassays using single-chain antibodiesCheryl L Baird
Pacific Northwest National Laboratory, Richland, WA 99352, USA
Anal Biochem 419:333-5. 2011..We demonstrate that scFvs can be used in such assays to improve reliability by reducing heterophilic antibody interference, thereby improving biomarker analysis and validation...
Immobilization strategies for single-chain antibody microarraysShannon L Seurynck-Servoss
Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99354, USA
Proteomics 8:2199-210. 2008..Overall, these results suggest that minor modifications of the scFv construct are sufficient to produce reagents that are suitable for use in multiplex assay systems...
Evaluation of surface chemistries for antibody microarraysShannon L Seurynck Servoss
Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99354, USA
Anal Biochem 371:105-15. 2007....
Construction and screening of antigen targeted immune yeast surface display antibody librariesKeith D Miller
Pacific Northwest National Laboratory, Richland, Washington, USA
Curr Protoc Cytom . 2008..Library construction and screening can be accomplished in as little as 2 weeks, resulting in a panel of scFvs specific for the target antigen...
Engineering an ultra-stable affinity reagent based on Top7Curt B Boschek
Cell Biology and Biochemistry Group, Bioinformatics Group, Pacific Northwest National Laboratory, PO Box 999, MS K4 12, Richland, WA 99352, USA
Protein Eng Des Sel 22:325-32. 2009..This CD4-specific protein demonstrates the functionality of Top7 as a viable scaffold for use as a general affinity reagent which could serve as a robust and inexpensive alternative to antibodies...
Surface chemistries for antibody microarraysShannon L Seurynck Servoss
Pacific Northwest National Laboratory, Biological Sciences Division, Richland, WA 99354, USA
Front Biosci 12:3956-64. 2007..In this review we compare and contrast the commercially available slide chemistries, as well as highlight some promising recent advances in the field...
