M J Gray
Affiliation: OSI Pharmaceuticals
- Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liverM J Gray
Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Oncogene 27:7192-200. 2008..006). We conclude that Id2 is upregulated in CRC, and is important in promoting cell survival. In vivo targeting of Id2 by siRNA establishes that it is a valid therapeutic target where its expression occurs...
- Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cellsJ S Wey
Department of Surgical Oncology, Unit 444, The University of Texas, MD Anderson Cancer Center, PO Box 301402, Houston, TX 77230 1402, USA
Br J Cancer 93:233-41. 2005..Targeting NRP-1 in pancreatic cancer cells may downregulate survival signalling pathways and increase sensitivity to chemotherapy...