Qing Shuo Zhang

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. doi request reprint The Sirt1 activator SRT3025 expands hematopoietic stem and progenitor cells and improves hematopoiesis in Fanconi anemia mice
    Qing Shuo Zhang
    Oregon Stem Cell Center, Department of Pediatrics, Oregon Health and Science University, Portland, OR 97239, USA Electronic address
    Stem Cell Res 15:130-40. 2015
  2. pmc Oxymetholone therapy of fanconi anemia suppresses osteopontin transcription and induces hematopoietic stem cell cycling
    Qing Shuo Zhang
    Oregon Stem Cell Center, Department of Pediatrics, Oregon Health and Science University, Portland, OR 97239, USA Electronic address
    Stem Cell Reports 4:90-102. 2015
  3. pmc Fancd2 and p21 function independently in maintaining the size of hematopoietic stem and progenitor cell pool in mice
    Qing Shuo Zhang
    Oregon Stem Cell Center, Department of Pediatrics, Oregon Health and Science University, Portland, OR 97239, USA
    Stem Cell Res 11:687-92. 2013
  4. doi request reprint Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice
    Qing Shuo Zhang
    Oregon Stem Cell Center, Oregon Health and Science University, Portland, OR 97239, USA
    Cancer Res 68:1601-8. 2008
  5. pmc Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol
    Qing Shuo Zhang
    Oregon Stem Cell Center, Department of Pediatrics, Oregon Health and Science University, Portland, OR, USA
    Blood 116:5140-8. 2010
  6. pmc Evaluation of resveratrol and N-acetylcysteine for cancer chemoprevention in a Fanconi anemia murine model
    Qing Shuo Zhang
    Oregon Stem Cell Center, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon
    Pediatr Blood Cancer 61:740-2. 2014
  7. pmc Non-invasive stem cell therapy in a rat model for retinal degeneration and vascular pathology
    Shaomei Wang
    Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America
    PLoS ONE 5:e9200. 2010

Detail Information

Publications7

  1. doi request reprint The Sirt1 activator SRT3025 expands hematopoietic stem and progenitor cells and improves hematopoiesis in Fanconi anemia mice
    Qing Shuo Zhang
    Oregon Stem Cell Center, Department of Pediatrics, Oregon Health and Science University, Portland, OR 97239, USA Electronic address
    Stem Cell Res 15:130-40. 2015
    ..Overall, our data indicate that SRT3025 or related compounds may be beneficial in Fanconi anemia and other bone marrow failure syndromes. ..
  2. pmc Oxymetholone therapy of fanconi anemia suppresses osteopontin transcription and induces hematopoietic stem cell cycling
    Qing Shuo Zhang
    Oregon Stem Cell Center, Department of Pediatrics, Oregon Health and Science University, Portland, OR 97239, USA Electronic address
    Stem Cell Reports 4:90-102. 2015
    ..These results expand our knowledge of the regulation of hematopoietic stem cell proliferation and have direct clinical implications for the treatment of bone marrow failure. ..
  3. pmc Fancd2 and p21 function independently in maintaining the size of hematopoietic stem and progenitor cell pool in mice
    Qing Shuo Zhang
    Oregon Stem Cell Center, Department of Pediatrics, Oregon Health and Science University, Portland, OR 97239, USA
    Stem Cell Res 11:687-92. 2013
    ..Collectively, our data indicate that p21 has an indispensable role in maintaining a normal HSPC pool and suggest that other p53-targeted factors, not p21, mediate the progressive elimination of HSPC in Fanconi anemia. ..
  4. doi request reprint Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice
    Qing Shuo Zhang
    Oregon Stem Cell Center, Oregon Health and Science University, Portland, OR 97239, USA
    Cancer Res 68:1601-8. 2008
    ..The reduction in oxidative DNA damage in tempol-treated FA fibroblasts and mice suggests that its tumor-delaying function may be attributed to its antioxidant activity...
  5. pmc Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol
    Qing Shuo Zhang
    Oregon Stem Cell Center, Department of Pediatrics, Oregon Health and Science University, Portland, OR, USA
    Blood 116:5140-8. 2010
    ..We conclude that Fancd2(-/-) mice have readily quantifiable hematopoietic defects, and that this model is well suited for pharmacologic screening studies...
  6. pmc Evaluation of resveratrol and N-acetylcysteine for cancer chemoprevention in a Fanconi anemia murine model
    Qing Shuo Zhang
    Oregon Stem Cell Center, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon
    Pediatr Blood Cancer 61:740-2. 2014
    ..In addition, when given to Fancd2(-/-) mice, NAC helped maintain Fancd2(-/-) KSL cells in quiescence while tempol did not. The mechanisms behind the different actions of these antioxidants await further investigation...
  7. pmc Non-invasive stem cell therapy in a rat model for retinal degeneration and vascular pathology
    Shaomei Wang
    Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America
    PLoS ONE 5:e9200. 2010
    ....