S Zareparsi

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Segregation analysis of Parkinson disease
    S Zareparsi
    Department of Molecular and Medical Genetics, Oregon Health Sciences University, Portland 97201, USA
    Am J Med Genet 80:410-7. 1998
  2. ncbi request reprint HLA-A2 homozygosity but not heterozygosity is associated with Alzheimer disease
    S Zareparsi
    Department of Neurology, Oregon Health Sciences University, Portland 97201, USA
    Neurology 58:973-5. 2002
  3. ncbi request reprint Age at onset of Parkinson disease and apolipoprotein E genotypes
    Sepideh Zareparsi
    Department of Neurology, Oregon Health Sciences University, Portland, Oregon 97201, USA
    Am J Med Genet 107:156-61. 2002
  4. ncbi request reprint Exclusion of dominant mutations within the FTDP-17 locus on chromosome 17 for Parkinson's disease
    S Zareparsi
    Department of Molecular and Medical Genetics, Oregon Health Sciences University, Portland 97201, USA
    Neurosci Lett 272:140-2. 1999
  5. ncbi request reprint Predictors of healthy brain aging
    M Gonzales Mc Neal
    Departments of Molecular and Medical Genetics, Oregon Health Sciences University, Portland 97201, USA
    J Gerontol A Biol Sci Med Sci 56:B294-301. 2001
  6. ncbi request reprint Parkinson's disease, CYP2D6 polymorphism, and age
    H Payami
    Department of Neurology, Oregon Health Sciences University, Portland 97201, USA
    Neurology 56:1363-70. 2001
  7. ncbi request reprint Familial aggregation of Parkinson disease: a comparative study of early-onset and late-onset disease
    Haydeh Payami
    Department of Neurology, CR131, Oregon Health Sciences University, 3181 SW Sam Jackson Park Rd, Portland, OR 97201, USA
    Arch Neurol 59:848-50. 2002
  8. ncbi request reprint Association of apolipoprotein E alleles with susceptibility to age-related macular degeneration in a large cohort from a single center
    Sepideh Zareparsi
    Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105, USA
    Invest Ophthalmol Vis Sci 45:1306-10. 2004
  9. ncbi request reprint Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration
    Caroline Hayward
    MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK
    Hum Mol Genet 12:2657-67. 2003
  10. ncbi request reprint Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration
    Sepideh Zareparsi
    Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI 48105, USA
    Hum Mol Genet 14:1449-55. 2005

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Segregation analysis of Parkinson disease
    S Zareparsi
    Department of Molecular and Medical Genetics, Oregon Health Sciences University, Portland 97201, USA
    Am J Med Genet 80:410-7. 1998
    ....
  2. ncbi request reprint HLA-A2 homozygosity but not heterozygosity is associated with Alzheimer disease
    S Zareparsi
    Department of Neurology, Oregon Health Sciences University, Portland 97201, USA
    Neurology 58:973-5. 2002
    ..4 years, p = 0.002) or those without A2 (5.2 years, p = 0.003). The "recessive" nature of this association suggests that loss of function at the HLA-A locus or a closely linked gene is associated with AD...
  3. ncbi request reprint Age at onset of Parkinson disease and apolipoprotein E genotypes
    Sepideh Zareparsi
    Department of Neurology, Oregon Health Sciences University, Portland, Oregon 97201, USA
    Am J Med Genet 107:156-61. 2002
    ..There was a trend for earlier onset of PD in varepsilon2varepsilon3 patients than in varepsilon3varepsilon3 patients only in the Oregon sample. In conclusion, APOE is associated with age at onset of PD...
  4. ncbi request reprint Exclusion of dominant mutations within the FTDP-17 locus on chromosome 17 for Parkinson's disease
    S Zareparsi
    Department of Molecular and Medical Genetics, Oregon Health Sciences University, Portland 97201, USA
    Neurosci Lett 272:140-2. 1999
    ..We found no evidence for linkage and excluded the 6cM candidate region which suggest that in our families, PD is not caused by dominant mutations within tau...
  5. ncbi request reprint Predictors of healthy brain aging
    M Gonzales Mc Neal
    Departments of Molecular and Medical Genetics, Oregon Health Sciences University, Portland 97201, USA
    J Gerontol A Biol Sci Med Sci 56:B294-301. 2001
    ..In this population, absence of apolipoprotein E-epsilon4 and male gender were associated with delayed onset, whereas estrogen use and education had no detectable effect on cognitive outcome...
  6. ncbi request reprint Parkinson's disease, CYP2D6 polymorphism, and age
    H Payami
    Department of Neurology, Oregon Health Sciences University, Portland 97201, USA
    Neurology 56:1363-70. 2001
    ..The aim of this study was to test if the CYP2D6*4 allele (poor metabolizer phenotype) is associated with earlier age at onset...
  7. ncbi request reprint Familial aggregation of Parkinson disease: a comparative study of early-onset and late-onset disease
    Haydeh Payami
    Department of Neurology, CR131, Oregon Health Sciences University, 3181 SW Sam Jackson Park Rd, Portland, OR 97201, USA
    Arch Neurol 59:848-50. 2002
    ..Evidence for familial aggregation is key to whether research should focus on gene discovery or search for environmental factors...
  8. ncbi request reprint Association of apolipoprotein E alleles with susceptibility to age-related macular degeneration in a large cohort from a single center
    Sepideh Zareparsi
    Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105, USA
    Invest Ophthalmol Vis Sci 45:1306-10. 2004
    ..To examine the effect of apolipoprotein E (APOE) alleles on age-related macular degeneration (AMD) risk and on age at diagnosis of AMD in a large patient cohort recruited from a single center...
  9. ncbi request reprint Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration
    Caroline Hayward
    MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK
    Hum Mol Genet 12:2657-67. 2003
    ..These results indicate a novel disease mechanism involving abnormal adhesion between RPE and Bruch's membrane...
  10. ncbi request reprint Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration
    Sepideh Zareparsi
    Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI 48105, USA
    Hum Mol Genet 14:1449-55. 2005
    ..Our data provide evidence of a link between multiple diverse mechanisms underlying AMD pathogenesis...