K L Winthrop

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. pmc Pulmonary disease associated with nontuberculous mycobacteria, Oregon, USA
    Kevin L Winthrop
    Oregon Health and Sciences University, Portland, Oregon, USA
    Emerg Infect Dis 17:1760-1. 2011
  2. ncbi request reprint Persistence of Staphylococcus aureus colonization among individuals with immune-mediated inflammatory diseases treated with TNF-α inhibitor therapy
    Cara D Varley
    Oregon Health and Science University, 3375 SW Terwilliger Blvd, Portland, OR 97239, USA
    Rheumatology (Oxford) 53:332-7. 2014
  3. doi request reprint Bedfellows: mycobacteria and rheumatoid arthritis in the era of biologic therapy
    Kevin L Winthrop
    Division of Infectious Diseases, Public Health and Preventive Medicine, Oregon Health and Science University, Terwilliger Boulevard, Portland, OR 97239, USA
    Nat Rev Rheumatol 9:524-31. 2013
  4. pmc Association between the initiation of anti-tumor necrosis factor therapy and the risk of herpes zoster
    Kevin L Winthrop
    Division of Infectious Diseases, Public Health and Preventive Medicine, Oregon Health and Science University, OR 97239, USA
    JAMA 309:887-95. 2013
  5. doi request reprint Mycobacterial diseases and antitumour necrosis factor therapy in USA
    K L Winthrop
    Oregon Health Sciences University, Portland, OR, USA
    Ann Rheum Dis 72:37-42. 2013
  6. doi request reprint Initiation of anti-TNF therapy and the risk of optic neuritis: from the safety assessment of biologic ThERapy (SABER) Study
    Kevin L Winthrop
    Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239, USA
    Am J Ophthalmol 155:183-189.e1. 2013
  7. doi request reprint Infections and biologic therapy in rheumatoid arthritis: our changing understanding of risk and prevention
    Kevin L Winthrop
    Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR, USA
    Rheum Dis Clin North Am 38:727-45. 2012
  8. pmc The use, safety, and effectiveness of herpes zoster vaccination in individuals with inflammatory and autoimmune diseases: a longitudinal observational study
    Jie Zhang
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1665 University Blvd, Birmingham, AL 35294, USA
    Arthritis Res Ther 13:R174. 2011
  9. doi request reprint High level disinfection of a home care device; to boil or not to boil?
    K L Winthrop
    Division of Infectious Diseases, Oregon Health and Science University, Portland, OR 97239, USA
    J Hosp Infect 80:262-4. 2012
  10. doi request reprint Pulmonary nontuberculous mycobacterial disease prevalence and clinical features: an emerging public health disease
    Kevin L Winthrop
    Oregon Health and Science University, Portland, OR 97239, USA
    Am J Respir Crit Care Med 182:977-82. 2010

Detail Information

Publications35

  1. pmc Pulmonary disease associated with nontuberculous mycobacteria, Oregon, USA
    Kevin L Winthrop
    Oregon Health and Sciences University, Portland, Oregon, USA
    Emerg Infect Dis 17:1760-1. 2011
    ..The current distribution of pulmonary NTM disease has been poorly characterized with regard to environment, climate, and other factors...
  2. ncbi request reprint Persistence of Staphylococcus aureus colonization among individuals with immune-mediated inflammatory diseases treated with TNF-α inhibitor therapy
    Cara D Varley
    Oregon Health and Science University, 3375 SW Terwilliger Blvd, Portland, OR 97239, USA
    Rheumatology (Oxford) 53:332-7. 2014
    ..We investigated the relationship between Staphylococcus aureus colonization and the use of immunosuppressive therapies in patients with immune-mediated inflammatory diseases (IMIDs)...
  3. doi request reprint Bedfellows: mycobacteria and rheumatoid arthritis in the era of biologic therapy
    Kevin L Winthrop
    Division of Infectious Diseases, Public Health and Preventive Medicine, Oregon Health and Science University, Terwilliger Boulevard, Portland, OR 97239, USA
    Nat Rev Rheumatol 9:524-31. 2013
    ..This article reviews our most recent understanding of the epidemiological and clinical aspects of mycobacterial disease as it relates to RA, and the existing and emerging immunosuppressive therapies used to treat this disease. ..
  4. pmc Association between the initiation of anti-tumor necrosis factor therapy and the risk of herpes zoster
    Kevin L Winthrop
    Division of Infectious Diseases, Public Health and Preventive Medicine, Oregon Health and Science University, OR 97239, USA
    JAMA 309:887-95. 2013
    ..Herpes zoster reactivation disproportionately affects patients with rheumatoid arthritis (RA). It is unclear whether anti-tumor necrosis factor (anti-TNF) therapy elevates herpes zoster risk...
  5. doi request reprint Mycobacterial diseases and antitumour necrosis factor therapy in USA
    K L Winthrop
    Oregon Health Sciences University, Portland, OR, USA
    Ann Rheum Dis 72:37-42. 2013
    ..In North America, tuberculosis and nontuberculous mycobacterial (NTM) disease rates associated with antitumour necrosis factor α (anti-TNFα) therapy are unknown...
  6. doi request reprint Initiation of anti-TNF therapy and the risk of optic neuritis: from the safety assessment of biologic ThERapy (SABER) Study
    Kevin L Winthrop
    Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239, USA
    Am J Ophthalmol 155:183-189.e1. 2013
    ..To evaluate the incidence of optic neuritis (ON) in patients using anti-tumor necrosis factor (TNF) alpha therapy...
  7. doi request reprint Infections and biologic therapy in rheumatoid arthritis: our changing understanding of risk and prevention
    Kevin L Winthrop
    Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR, USA
    Rheum Dis Clin North Am 38:727-45. 2012
    ..Some of the important causes of infectious morbidity in this setting are preventable with screening (eg, tuberculosis) or vaccination (eg, herpes zoster)...
  8. pmc The use, safety, and effectiveness of herpes zoster vaccination in individuals with inflammatory and autoimmune diseases: a longitudinal observational study
    Jie Zhang
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1665 University Blvd, Birmingham, AL 35294, USA
    Arthritis Res Ther 13:R174. 2011
    ....
  9. doi request reprint High level disinfection of a home care device; to boil or not to boil?
    K L Winthrop
    Division of Infectious Diseases, Oregon Health and Science University, Portland, OR 97239, USA
    J Hosp Infect 80:262-4. 2012
    ..1, >6.3 and >5.5 for S. aureus, P. aeruginosa and C. albicans, respectively, but only 4.6 for M. terrae. At 15 min the reductions had increased to 7.5, >6.8, >6.6 and >7.5 cfu, respectively...
  10. doi request reprint Pulmonary nontuberculous mycobacterial disease prevalence and clinical features: an emerging public health disease
    Kevin L Winthrop
    Oregon Health and Science University, Portland, OR 97239, USA
    Am J Respir Crit Care Med 182:977-82. 2010
    ..Respiratory specimens with nontuberculous mycobacteria (NTM) are increasingly common; however, pulmonary disease prevalence is unknown...
  11. pmc Nontuberculous mycobacteria infections and anti-tumor necrosis factor-alpha therapy
    Kevin L Winthrop
    Departments of Infectious Diseases, Ophthalmology, and Public Health and Preventive Medicine, Oregon Health and Sciences University, Portland, Oregon 97239, USA
    Emerg Infect Dis 15:1556-61. 2009
    ..Mycobacteria avium (n = 52, 50%) was most commonly implicated, and 9 patients (9%) had died at the time their infections were reported. A high rate of extrapulmonary manifestations (n = 46, 44%) was also reported...
  12. doi request reprint Preventing and treating biologic-associated opportunistic infections
    Kevin L Winthrop
    Oregon Health and Science University, Portland, OR, USA
    Nat Rev Rheumatol 5:405-10. 2009
    ....
  13. pmc Interferon-gamma release assays for diagnosing mycobacterium tuberculosis infection in renal dialysis patients
    Kevin L Winthrop
    Division of Tuberculosis Elimination, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Clin J Am Soc Nephrol 3:1357-63. 2008
    ..Outcome measures included the prevalence of positive test results, identification of factors associated with positive results, and test result discordance...
  14. doi request reprint Mycobacterial and other serious infections in patients receiving anti-tumor necrosis factor and other newly approved biologic therapies: case finding through the Emerging Infections Network
    Kevin L Winthrop
    Oregon Health and Sciences University, Portland 97239, USA
    Clin Infect Dis 46:1738-40. 2008
    ..Nontuberculous mycobacterial infections, histoplasmosis, and invasive Staphylococcus aureus infection were all reported more frequently than was tuberculosis disease in this context...
  15. ncbi request reprint Nontuberuclous mycobacterial disease: updated diagnostic criteria for an under-recognized infectious complication of anti-tumor necrosis factor therapy
    Kevin L Winthrop
    Division of Infectious Diseases, Ophthalmology, and Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR, USA
    Nat Clin Pract Rheumatol 3:E1. 2007
  16. doi request reprint The reliability of diagnostic coding and laboratory data to identify tuberculosis and nontuberculous mycobacterial disease among rheumatoid arthritis patients using anti-tumor necrosis factor therapy
    Kevin L Winthrop
    Oregon Health and Science University, Portland, OR, USA
    Pharmacoepidemiol Drug Saf 20:229-35. 2011
    ..Anti-tumor necrosis factor-alpha (anti-TNF) therapies are associated with severe mycobacterial infections in rheumatoid arthritis patients. We developed and validated electronic record search algorithms for these serious infections...
  17. pmc Serious infections with antirheumatic therapy: are biologicals worse?
    K L Winthrop
    Division of Infectious Diseases, School of Medicine, Oregon Health Sciences University, 3375 SW Terwilliger Boulevard, Portland, OR 97239 4197, USA
    Ann Rheum Dis 65:iii54-7. 2006
    ..In the meantime, the author recommends that physicians should remain vigilant for serious infections in their patients with RA and use appropriate vaccines and screening procedures to mitigate their risk...
  18. ncbi request reprint Risk and prevention of tuberculosis and other serious opportunistic infections associated with the inhibition of tumor necrosis factor
    Kevin L Winthrop
    Division of Infectious Diseases, Department of Medicine, Oregon Health and Science University, Portland, OR 97239 4197, USA
    Nat Clin Pract Rheumatol 2:602-10. 2006
    ..g. fungal) infections is far less certain...
  19. ncbi request reprint The reliability of anterior segment lesions as indicators of onchocercal eye disease in Guatemala
    Kevin L Winthrop
    Division of Parasitic Diseases, US Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Am J Trop Med Hyg 75:1058-62. 2006
    ..Our findings suggest that inflammatory punctate keratitis is neither a specific nor a reliable indicator of onchocercal eye disease. Future prevalence surveys should rely upon noninflammatory lesions as disease indicators...
  20. pmc Update on tuberculosis and other opportunistic infections associated with drugs blocking tumour necrosis factor {alpha}
    K L Winthrop
    Good Samaritan Hospital Clinic, 1200 NW 23rd Avenue, Portland, Oregon 97210, USA
    Ann Rheum Dis 64:iv29-30. 2005
  21. ncbi request reprint Isolation of non-tuberculous mycobacteria from the sputum of patients with active tuberculosis
    B A Kendall
    Providence Newberg Medical Center, Newberg, Oregon, USA
    Int J Tuberc Lung Dis 14:654-6. 2010
    ..7, 95%CI 1.2-6.0) and were more likely to be born in the United States (RR 2.4, 95%CI 1.1-5.3). Further study is needed to determine the clinical significance of simultaneous isolation of NTM and TB...
  22. ncbi request reprint Mycobacterium marinum presenting as large verrucous plaques on the lower extremity of a South Pacific Islander
    Joseph V Lillis
    Department of Dermatology, Oregon Health Sciences University, Portland, Oregon 97239, USA
    Am J Trop Med Hyg 79:166-7. 2008
    ..marinum. This morphology, distribution, and disease course is likely representative of an atypical presentation of M. marinum infection in South Pacific Islanders...
  23. doi request reprint Update on rheumatic manifestations of infectious diseases
    Jennifer Becker
    Oregon Health and Science University, Portland, Oregon, USA
    Curr Opin Rheumatol 22:72-7. 2010
    ..Herein, we review important recent clinical, epidemiologic, and basic science advances within this area of rheumatology...
  24. doi request reprint Treatment patterns of pediatric nontuberculous mycobacterial (NTM) cervical lymphadenitis as reported by nationwide surveys of pediatric otolaryngology and infectious disease societies
    E F Pilkington
    Oregon Health and Science University, Portland, OR, USA
    Int J Pediatr Otorhinolaryngol 74:343-6. 2010
    ..To describe physician diagnostic and therapeutic strategies for pediatric nontuberculous mycobacterial (NTM) lymphadenitis, a disease for which surgical excision is recommended...
  25. ncbi request reprint Tuberculosis associated with therapy against tumor necrosis factor alpha
    Kevin L Winthrop
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Arthritis Rheum 52:2968-74. 2005
  26. ncbi request reprint Transmission of mycobacterium tuberculosis via lung transplantation
    Kevin L Winthrop
    Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Am J Transplant 4:1529-33. 2004
    ..Tuberculosis was transmitted from lung donor to recipient. As organ transplantation becomes more common worldwide, similar cases could occur. Screening for TB in potential organ donors should be considered...
  27. doi request reprint Sequelae of World War II: an outbreak of chronic cutaneous nontuberculous mycobacterial infection among Satowanese islanders
    Joseph V Lillis
    Department of Dermatology, School of Medicine, Oregon Health and Science University, Portland, Oregon, USA
    Clin Infect Dis 48:1541-6. 2009
    ..After World War II, residents of Satowan (population, 650 persons), an outer island in the state of Chuuk, Federated States of Micronesia, noted a high prevalence of a chronic, progressive skin disease known locally as "spam."..
  28. ncbi request reprint Investigation of human contacts: a Mycobacterium bovis outbreak among cattle at a California dairy
    K L Winthrop
    Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Int J Tuberc Lung Dis 9:809-13. 2005
    ..In May 2002, a Mycobacterium bovis outbreak occurred among cattle at a California dairy. We investigated to determine whether persons were infected after working with the cattle or drinking their raw milk...
  29. doi request reprint Nontuberculous mycobacterial disease prevalence and risk factors: a changing epidemiology
    P Maureen Cassidy
    Department of Human Services, Oregon Public Health Division, Portland, USA
    Clin Infect Dis 49:e124-9. 2009
    ..We sought to estimate NTM disease prevalence in Oregon, and describe disease by site, species, and patient demographic characteristics...
  30. ncbi request reprint An outbreak of mycobacterial furunculosis associated with footbaths at a nail salon
    Kevin L Winthrop
    Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, USA
    N Engl J Med 346:1366-71. 2002
    ..The patients had received pedicures at the same nail salon. We identified and investigated an outbreak of Mycobacterium fortuitum furunculosis among customers of this nail salon...
  31. ncbi request reprint Epidemic and sporadic cases of nontuberculous mycobacterial keratitis associated with laser in situ keratomileusis
    Kevin L Winthrop
    Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Am J Ophthalmol 135:223-4. 2003
    ..To report national case-finding results for nontuberculous mycobacterial keratitis and describe its association with laser in situ keratomileusis (LASIK)...
  32. doi request reprint American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis
    Kenneth G Saag
    University of Alabama, Birmingham, AL, USA
    Arthritis Rheum 59:762-84. 2008
  33. ncbi request reprint Tuberculosis cases associated with infliximab and etanercept
    Kevin L Winthrop
    Clin Infect Dis 39:1256-7. 2004
  34. ncbi request reprint The clinical management and outcome of nail salon-acquired Mycobacterium fortuitum skin infection
    Kevin L Winthrop
    Epidemic Intelligence Service, Centers for Disease Control and Prevention at the California Department of Health Services, Berkeley, California 94704, USA
    Clin Infect Dis 38:38-44. 2004
    ..Early administration of therapy was associated with shorter duration of disease only in persons with multiple boils (P<.01). One untreated, healthy patient had lymphatic disease dissemination...
  35. ncbi request reprint Exposure to rodents and rodent-borne viruses among persons with elevated occupational risk
    Curtis L Fritz
    California Department of Health Services, Division of Communicable Disease Control, P O Box 942732, MS 486, Sacramento, CA 94234 7320, USA
    J Occup Environ Med 44:962-7. 2002
    ..IgG antibody to SNV, WWA, and Amapari viruses was not detected in any of the serum specimens. Despite considerable exposure to rodents, participants did not have significant serological evidence of exposure to rodent-borne viruses...