Research Topics
Species | K L WinthropSummaryAffiliation: Oregon Health and Science University Country: USA Publications
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Publications
Association between the initiation of anti-tumor necrosis factor therapy and the risk of herpes zosterKevin L Winthrop
Division of Infectious Diseases, Public Health and Preventive Medicine, Oregon Health and Science University, OR 97239, USA
JAMA 309:887-95. 2013..Herpes zoster reactivation disproportionately affects patients with rheumatoid arthritis (RA). It is unclear whether anti-tumor necrosis factor (anti-TNF) therapy elevates herpes zoster risk...- Mycobacterial diseases and antitumour necrosis factor therapy in USAK L Winthrop
Oregon Health Sciences University, Portland, OR, USA
Ann Rheum Dis 72:37-42. 2013..In North America, tuberculosis and nontuberculous mycobacterial (NTM) disease rates associated with antitumour necrosis factor α (anti-TNFα) therapy are unknown... - Initiation of anti-TNF therapy and the risk of optic neuritis: from the safety assessment of biologic ThERapy (SABER) StudyKevin L Winthrop
Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239, USA
Am J Ophthalmol 155:183-189.e1. 2013..To evaluate the incidence of optic neuritis (ON) in patients using anti-tumor necrosis factor (TNF) alpha therapy... - Infections and biologic therapy in rheumatoid arthritis: our changing understanding of risk and preventionKevin L Winthrop
Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR, USA
Rheum Dis Clin North Am 38:727-45. 2012..Some of the important causes of infectious morbidity in this setting are preventable with screening (eg, tuberculosis) or vaccination (eg, herpes zoster)... 
The use, safety, and effectiveness of herpes zoster vaccination in individuals with inflammatory and autoimmune diseases: a longitudinal observational studyJie Zhang
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1665 University Blvd, Birmingham, AL 35294, USA
Arthritis Res Ther 13:R174. 2011....- High level disinfection of a home care device; to boil or not to boil?K L Winthrop
Division of Infectious Diseases, Oregon Health and Science University, Portland, OR 97239, USA
J Hosp Infect 80:262-4. 2012..1, >6.3 and >5.5 for S. aureus, P. aeruginosa and C. albicans, respectively, but only 4.6 for M. terrae. At 15 min the reductions had increased to 7.5, >6.8, >6.6 and >7.5 cfu, respectively... - Interferon-gamma release assays for diagnosing mycobacterium tuberculosis infection in renal dialysis patientsKevin L Winthrop
Division of Tuberculosis Elimination, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin J Am Soc Nephrol 3:1357-63. 2008..Outcome measures included the prevalence of positive test results, identification of factors associated with positive results, and test result discordance... - Preventing and treating biologic-associated opportunistic infectionsKevin L Winthrop
Oregon Health and Science University, Portland, OR, USA
Nat Rev Rheumatol 5:405-10. 2009.... - Nontuberculous mycobacteria infections and anti-tumor necrosis factor-alpha therapyKevin L Winthrop
Departments of Infectious Diseases, Ophthalmology, and Public Health and Preventive Medicine, Oregon Health and Sciences University, Portland, Oregon 97239, USA
Emerg Infect Dis 15:1556-61. 2009..Mycobacteria avium (n = 52, 50%) was most commonly implicated, and 9 patients (9%) had died at the time their infections were reported. A high rate of extrapulmonary manifestations (n = 46, 44%) was also reported... - Pulmonary nontuberculous mycobacterial disease prevalence and clinical features: an emerging public health diseaseKevin L Winthrop
Oregon Health and Science University, Portland, OR 97239, USA
Am J Respir Crit Care Med 182:977-82. 2010..Respiratory specimens with nontuberculous mycobacteria (NTM) are increasingly common; however, pulmonary disease prevalence is unknown... - The reliability of diagnostic coding and laboratory data to identify tuberculosis and nontuberculous mycobacterial disease among rheumatoid arthritis patients using anti-tumor necrosis factor therapyKevin L Winthrop
Oregon Health and Science University, Portland, OR, USA
Pharmacoepidemiol Drug Saf 20:229-35. 2011..Anti-tumor necrosis factor-alpha (anti-TNF) therapies are associated with severe mycobacterial infections in rheumatoid arthritis patients. We developed and validated electronic record search algorithms for these serious infections... - Mycobacterial and other serious infections in patients receiving anti-tumor necrosis factor and other newly approved biologic therapies: case finding through the Emerging Infections NetworkKevin L Winthrop
Oregon Health and Sciences University, Portland 97239, USA
Clin Infect Dis 46:1738-40. 2008..Nontuberculous mycobacterial infections, histoplasmosis, and invasive Staphylococcus aureus infection were all reported more frequently than was tuberculosis disease in this context... 
Nontuberuclous mycobacterial disease: updated diagnostic criteria for an under-recognized infectious complication of anti-tumor necrosis factor therapyKevin L Winthrop
Division of Infectious Diseases, Ophthalmology, and Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR, USA
Nat Clin Pract Rheumatol 3:E1. 2007- The reliability of anterior segment lesions as indicators of onchocercal eye disease in GuatemalaKevin L Winthrop
Division of Parasitic Diseases, US Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Trop Med Hyg 75:1058-62. 2006..Our findings suggest that inflammatory punctate keratitis is neither a specific nor a reliable indicator of onchocercal eye disease. Future prevalence surveys should rely upon noninflammatory lesions as disease indicators... - Risk and prevention of tuberculosis and other serious opportunistic infections associated with the inhibition of tumor necrosis factorKevin L Winthrop
Division of Infectious Diseases, Department of Medicine, Oregon Health and Science University, Portland, OR 97239 4197, USA
Nat Clin Pract Rheumatol 2:602-10. 2006..g. fungal) infections is far less certain... - Serious infections with antirheumatic therapy: are biologicals worse?K L Winthrop
Division of Infectious Diseases, School of Medicine, Oregon Health Sciences University, 3375 SW Terwilliger Boulevard, Portland, OR 97239 4197, USA
Ann Rheum Dis 65:iii54-7. 2006..In the meantime, the author recommends that physicians should remain vigilant for serious infections in their patients with RA and use appropriate vaccines and screening procedures to mitigate their risk... - Update on tuberculosis and other opportunistic infections associated with drugs blocking tumour necrosis factor {alpha}K L Winthrop
Good Samaritan Hospital Clinic, 1200 NW 23rd Avenue, Portland, Oregon 97210, USA
Ann Rheum Dis 64:iv29-30. 2005 - Mycobacterium marinum presenting as large verrucous plaques on the lower extremity of a South Pacific IslanderJoseph V Lillis
Department of Dermatology, Oregon Health Sciences University, Portland, Oregon 97239, USA
Am J Trop Med Hyg 79:166-7. 2008..marinum. This morphology, distribution, and disease course is likely representative of an atypical presentation of M. marinum infection in South Pacific Islanders... - Update on rheumatic manifestations of infectious diseasesJennifer Becker
Oregon Health and Science University, Portland, Oregon, USA
Curr Opin Rheumatol 22:72-7. 2010..Herein, we review important recent clinical, epidemiologic, and basic science advances within this area of rheumatology... - Treatment patterns of pediatric nontuberculous mycobacterial (NTM) cervical lymphadenitis as reported by nationwide surveys of pediatric otolaryngology and infectious disease societiesE F Pilkington
Oregon Health and Science University, Portland, OR, USA
Int J Pediatr Otorhinolaryngol 74:343-6. 2010..To describe physician diagnostic and therapeutic strategies for pediatric nontuberculous mycobacterial (NTM) lymphadenitis, a disease for which surgical excision is recommended... - Transmission of mycobacterium tuberculosis via lung transplantationKevin L Winthrop
Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, GA, USA
Am J Transplant 4:1529-33. 2004..Tuberculosis was transmitted from lung donor to recipient. As organ transplantation becomes more common worldwide, similar cases could occur. Screening for TB in potential organ donors should be considered... - Tuberculosis associated with therapy against tumor necrosis factor alphaKevin L Winthrop
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Arthritis Rheum 52:2968-74. 2005 - Sequelae of World War II: an outbreak of chronic cutaneous nontuberculous mycobacterial infection among Satowanese islandersJoseph V Lillis
Department of Dermatology, School of Medicine, Oregon Health and Science University, Portland, Oregon, USA
Clin Infect Dis 48:1541-6. 2009..After World War II, residents of Satowan (population, 650 persons), an outer island in the state of Chuuk, Federated States of Micronesia, noted a high prevalence of a chronic, progressive skin disease known locally as "spam.".. - Investigation of human contacts: a Mycobacterium bovis outbreak among cattle at a California dairyK L Winthrop
Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Int J Tuberc Lung Dis 9:809-13. 2005..In May 2002, a Mycobacterium bovis outbreak occurred among cattle at a California dairy. We investigated to determine whether persons were infected after working with the cattle or drinking their raw milk... - An outbreak of mycobacterial furunculosis associated with footbaths at a nail salonKevin L Winthrop
Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, USA
N Engl J Med 346:1366-71. 2002..The patients had received pedicures at the same nail salon. We identified and investigated an outbreak of Mycobacterium fortuitum furunculosis among customers of this nail salon... - Nontuberculous mycobacterial disease prevalence and risk factors: a changing epidemiologyP Maureen Cassidy
Department of Human Services, Oregon Public Health Division, Portland, USA
Clin Infect Dis 49:e124-9. 2009..We sought to estimate NTM disease prevalence in Oregon, and describe disease by site, species, and patient demographic characteristics... - Epidemic and sporadic cases of nontuberculous mycobacterial keratitis associated with laser in situ keratomileusisKevin L Winthrop
Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Am J Ophthalmol 135:223-4. 2003..To report national case-finding results for nontuberculous mycobacterial keratitis and describe its association with laser in situ keratomileusis (LASIK)... - American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritisKenneth G Saag
University of Alabama, Birmingham, AL, USA
Arthritis Rheum 59:762-84. 2008 - The clinical management and outcome of nail salon-acquired Mycobacterium fortuitum skin infectionKevin L Winthrop
Epidemic Intelligence Service, Centers for Disease Control and Prevention at the California Department of Health Services, Berkeley, California 94704, USA
Clin Infect Dis 38:38-44. 2004..Early administration of therapy was associated with shorter duration of disease only in persons with multiple boils (P<.01). One untreated, healthy patient had lymphatic disease dissemination... - Exposure to rodents and rodent-borne viruses among persons with elevated occupational riskCurtis L Fritz
California Department of Health Services, Division of Communicable Disease Control, P O Box 942732, MS 486, Sacramento, CA 94234 7320, USA
J Occup Environ Med 44:962-7. 2002..IgG antibody to SNV, WWA, and Amapari viruses was not detected in any of the serum specimens. Despite considerable exposure to rodents, participants did not have significant serological evidence of exposure to rodent-borne viruses... - Tuberculosis cases associated with infliximab and etanerceptKevin L Winthrop
Clin Infect Dis 39:1256-7. 2004