A D Weinberg

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Antibodies to OX-40 (CD134) can identify and eliminate autoreactive T cells: implications for human autoimmune disease
    A D Weinberg
    Laboratory of Basic Immunology, Earle A Chiles Research Institute, Providence Portland Medical Center, OR 97213, USA
    Mol Med Today 4:76-83. 1998
  2. ncbi request reprint Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis
    A D Weinberg
    Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR 97213, USA
    J Immunol 162:1818-26. 1999
  3. ncbi request reprint Engagement of the OX-40 receptor in vivo enhances antitumor immunity
    A D Weinberg
    Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR 97213, USA
    J Immunol 164:2160-9. 2000
  4. ncbi request reprint Induction of anti-mammary cancer immunity by engaging the OX-40 receptor in vivo
    A Morris
    Department of Surgery, Oregon Health Sciences University, Portland, USA
    Breast Cancer Res Treat 67:71-80. 2001
  5. ncbi request reprint Engagement of OX40 enhances antigen-specific CD4(+) T cell mobilization/memory development and humoral immunity: comparison of alphaOX-40 with alphaCTLA-4
    D E Evans
    Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR 97213, USA
    J Immunol 167:6804-11. 2001

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Antibodies to OX-40 (CD134) can identify and eliminate autoreactive T cells: implications for human autoimmune disease
    A D Weinberg
    Laboratory of Basic Immunology, Earle A Chiles Research Institute, Providence Portland Medical Center, OR 97213, USA
    Mol Med Today 4:76-83. 1998
    ..This approach uses an antibody directed against a cell-surface protein (OX-40, also known as CD134) that is selectively upregulated on activated autoantigen-specific T cells within the inflamed tissue...
  2. ncbi request reprint Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis
    A D Weinberg
    Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR 97213, USA
    J Immunol 162:1818-26. 1999
    ..Furthermore, the data suggest that agents designed to inhibit the OX-40L/OX-40R complex may be useful for treating autoimmune disease...
  3. ncbi request reprint Engagement of the OX-40 receptor in vivo enhances antitumor immunity
    A D Weinberg
    Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR 97213, USA
    J Immunol 164:2160-9. 2000
    ....
  4. ncbi request reprint Induction of anti-mammary cancer immunity by engaging the OX-40 receptor in vivo
    A Morris
    Department of Surgery, Oregon Health Sciences University, Portland, USA
    Breast Cancer Res Treat 67:71-80. 2001
    ..These results should have practical applications for treatment modalities for patients with breast cancer...
  5. ncbi request reprint Engagement of OX40 enhances antigen-specific CD4(+) T cell mobilization/memory development and humoral immunity: comparison of alphaOX-40 with alphaCTLA-4
    D E Evans
    Earle A Chiles Research Institute, Robert W Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR 97213, USA
    J Immunol 167:6804-11. 2001
    ..These studies demonstrate that OX40 engagement early after immunization with soluble Ag enhances long-term T cell and humoral immunity in a manner distinct from that provided by blocking CTLA-4...