HENRYK URBANSKI

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi Age-related changes in neuroendocrine rhythmic function in the rhesus macaque
    Henryk F Urbanski
    Division of Neuroscience, Oregon National Primate Research Center, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    Age (Dordr) 34:1111-21. 2012
  2. ncbi Microarray analysis of relative gene expression stability for selection of internal reference genes in the rhesus macaque brain
    Nigel C Noriega
    Division of Neuroscience, Oregon National Primate Research Center, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    BMC Mol Biol 11:47. 2010
  3. ncbi Role of circadian neuroendocrine rhythms in the control of behavior and physiology
    Henryk F Urbanski
    Division of Neuroscience, Oregon National Primate Research Center, Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oreg, USA
    Neuroendocrinology 93:211-22. 2011
  4. ncbi Gene expression profiling in the rhesus macaque: experimental design considerations
    Henryk F Urbanski
    Division of Neuroscience, Oregon National Primate Research Center, Beaverton, OR 97006, USA
    Methods 49:26-31. 2009
  5. ncbi A biphasic developmental pattern of circulating leptin in the male rhesus macaque (Macaca mulatta)
    H F Urbanski
    Division of Neuroscience, Oregon Regional Primate Research Center, Beaverton 97006, USA
    Endocrinology 139:2284-6. 1998
  6. ncbi Effect of caloric restriction on the 24-hour plasma DHEAS and cortisol profiles of young and old male rhesus macaques
    H F Urbanski
    Division of Neuroscience, Oregon National Primate Research Center, 505 N W 185 th Avenue, Beaverton, OR 97006, USA
    Ann N Y Acad Sci 1019:443-7. 2004
  7. ncbi Leptin and puberty
    H F Urbanski
    Division of Neuroscience, Oregon Regional Primate Research Center, 505 N W 185th Avenue, Beaverton, OR 97006, USA
    Trends Endocrinol Metab 12:428-9. 2001
  8. ncbi Regional distribution of glutamic acid decarboxylase (GAD65 and GAD67) mRNA in the hypothalamus of male rhesus macaques before and after puberty
    H F Urbanski
    Division of Neuroscience, Oregon Regional Primate Research Center, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    Brain Res Mol Brain Res 57:86-91. 1998
  9. ncbi Regional expression of mRNA encoding a second form of gonadotropin-releasing hormone in the macaque brain
    H F Urbanski
    Division of Neuroscience, Oregon Regional Primate Research Center, Beaverton 97006, USA
    Endocrinology 140:1945-8. 1999
  10. ncbi Accelerated immune senescence and reduced response to vaccination in ovariectomized female rhesus macaques
    Flora Engelmann
    Vaccine and Gene Therapy Institute, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 09006, USA
    Age (Dordr) 33:275-89. 2011

Research Grants

  1. Interacting Impact of Adrenal and Ovarian Aging on the CNS
    HENRYK URBANSKI; Fiscal Year: 2009
  2. Interacting Impact of Adrenal and Ovarian Aging on the CNS
    HENRYK URBANSKI; Fiscal Year: 2009
  3. Interacting Impact of Adrenal and Ovarian Aging on the CNS
    HENRYK URBANSKI; Fiscal Year: 2007
  4. Motor Function and Cognitive Decline in Aging Primates
    HENRYK URBANSKI; Fiscal Year: 2007
  5. Postnatal Development of Ionotropic Glutamate Receptors
    HENRYK URBANSKI; Fiscal Year: 2006
  6. Effect of Aging and Caloric Restriction on Circadian Ph*
    HENRYK URBANSKI; Fiscal Year: 2005
  7. Interacting Impact of Adrenal and Ovarian Aging on the CNS
    Henryk F Urbanski; Fiscal Year: 2010

Collaborators

  • Ilhem Messaoudi
  • Nigel C Noriega
  • M A Lane
  • D K Ingram
  • Sergio Ojeda
  • Julie A Mattison
  • Tamas Horvath
  • Jodi L Downs
  • Dario R Lemos
  • Flora Engelmann
  • V S Latimer
  • Steven G Kohama
  • V T Garyfallou
  • Vasilios T Garyfallou
  • V S Densmore
  • Sabrina Diano
  • Dawud Meeran
  • Valerie S Densmore
  • D I Brown
  • Alex Barron
  • Byung Park
  • Martha Neuringer
  • S G Kohama
  • Erzsebet Borok
  • Marya Shanabrough
  • Luciana Tonelli
  • Leela Goodspeed
  • Marina P Antoch
  • Michael R Dunn
  • Dario Lemos
  • Peter Sotonyi
  • Susan J Gregory
  • Julie Townsend
  • Domingo J Tortonese
  • Balazs Horvath
  • R B White
  • S M Rodrigues
  • R D Fernald

Detail Information

Publications25

  1. ncbi Age-related changes in neuroendocrine rhythmic function in the rhesus macaque
    Henryk F Urbanski
    Division of Neuroscience, Oregon National Primate Research Center, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    Age (Dordr) 34:1111-21. 2012
    ..Consequently, they represent an ideal translational animal model in which to study the causes and consequences of age-associated internal circadian disruption and in which to evaluate novel therapies...
  2. ncbi Microarray analysis of relative gene expression stability for selection of internal reference genes in the rhesus macaque brain
    Nigel C Noriega
    Division of Neuroscience, Oregon National Primate Research Center, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    BMC Mol Biol 11:47. 2010
    ..Twelve animals were used per study, and three brain regions were analyzed from each animal. Gene expression stabilities were determined using geNorm, NormFinder and BestKeeper software packages...
  3. ncbi Role of circadian neuroendocrine rhythms in the control of behavior and physiology
    Henryk F Urbanski
    Division of Neuroscience, Oregon National Primate Research Center, Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oreg, USA
    Neuroendocrinology 93:211-22. 2011
    ..In addition, this minireview raises awareness of the rhythmic expression patterns shown by many genes, and discusses how this could impact interpretation of data obtained from gene profiling studies, especially from nocturnal rodents...
  4. ncbi Gene expression profiling in the rhesus macaque: experimental design considerations
    Henryk F Urbanski
    Division of Neuroscience, Oregon National Primate Research Center, Beaverton, OR 97006, USA
    Methods 49:26-31. 2009
    ..In addition, the sex-steroid environment of humans and many nonhuman primates changes markedly across the menstrual cycle, and so phase of the cycle needs to be considered when studying gene expression in adult females...
  5. ncbi A biphasic developmental pattern of circulating leptin in the male rhesus macaque (Macaca mulatta)
    H F Urbanski
    Division of Neuroscience, Oregon Regional Primate Research Center, Beaverton 97006, USA
    Endocrinology 139:2284-6. 1998
    ....
  6. ncbi Effect of caloric restriction on the 24-hour plasma DHEAS and cortisol profiles of young and old male rhesus macaques
    H F Urbanski
    Division of Neuroscience, Oregon National Primate Research Center, 505 N W 185 th Avenue, Beaverton, OR 97006, USA
    Ann N Y Acad Sci 1019:443-7. 2004
    ..These data fail to support the hypothesis that CR can attenuate the aging-related decline in plasma DHEAS concentrations, at least not when initiated after puberty...
  7. ncbi Leptin and puberty
    H F Urbanski
    Division of Neuroscience, Oregon Regional Primate Research Center, 505 N W 185th Avenue, Beaverton, OR 97006, USA
    Trends Endocrinol Metab 12:428-9. 2001
    ..Instead, their results suggest that leptin is one of many permissive metabolic factors that allow pubertal development to proceed...
  8. ncbi Regional distribution of glutamic acid decarboxylase (GAD65 and GAD67) mRNA in the hypothalamus of male rhesus macaques before and after puberty
    H F Urbanski
    Division of Neuroscience, Oregon Regional Primate Research Center, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    Brain Res Mol Brain Res 57:86-91. 1998
    ....
  9. ncbi Regional expression of mRNA encoding a second form of gonadotropin-releasing hormone in the macaque brain
    H F Urbanski
    Division of Neuroscience, Oregon Regional Primate Research Center, Beaverton 97006, USA
    Endocrinology 140:1945-8. 1999
    ....
  10. ncbi Accelerated immune senescence and reduced response to vaccination in ovariectomized female rhesus macaques
    Flora Engelmann
    Vaccine and Gene Therapy Institute, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 09006, USA
    Age (Dordr) 33:275-89. 2011
    ....
  11. ncbi A developmental increase in the expression of messenger ribonucleic acid encoding a second form of gonadotropin-releasing hormone in the rhesus macaque hypothalamus
    V S Latimer
    Division of Neuroscience, Oregon Regional Primate Research Center, Beaverton, Oregon 97006, USA
    J Clin Endocrinol Metab 86:324-9. 2001
    ..Moreover, because GnRH-II can stimulate LH release in vivo, it is plausible that changes in its gene expression represent an important component of the mechanism by which the hypothalamus controls reproductive function...
  12. ncbi Photoperiodic modulation of GnRH mRNA in the male Syrian hamster
    D I Brown
    Division of Neuroscience, Oregon Regional Primate, Research Center, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    Brain Res Mol Brain Res 89:119-25. 2001
    ....
  13. ncbi Two molecular forms of gonadotropin-releasing hormone (GnRH-I and GnRH-II) are expressed by two separate populations of cells in the rhesus macaque hypothalamus
    V S Latimer
    Division of Neuroscience, Oregon Regional Primate Research Center, 505 NW 185th Avenue, Beaverton, OR, USA
    Brain Res Mol Brain Res 75:287-92. 2000
    ..This finding emphasizes that GnRH-I and GnRH-II are synthesized by two distinct populations of hypothalamic neurons, and suggests that they may be regulated by different neuroendocrine pathways...
  14. ncbi Effect of 17beta-estradiol on hypothalamic GnRH-II gene expression in the female rhesus macaque
    V S Densmore
    Division of Neuroscience, Oregon National Primate Research Center, 505 NW 185th Avenue, Beaverton, Oregon 97006, USA
    J Mol Endocrinol 33:145-53. 2004
    ..Taken together, these data give credence to a novel pathway by which E may control the primate neuroendocrine reproductive axis, one that involves stimulation of GnRH-II release via an ERbeta-mediated mechanism...
  15. ncbi Aging-related sex-dependent loss of the circulating leptin 24-h rhythm in the rhesus monkey
    Jodi L Downs
    Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA
    J Endocrinol 190:117-27. 2006
    ..Furthermore, they suggest that the underlying endocrine mechanism may be driven in part by a circadian clock mechanism...
  16. ncbi Orexin neuronal changes in the locus coeruleus of the aging rhesus macaque
    Jodi L Downs
    Division of Neuroscience, Oregon National Primate Research Center, Beaverton, OR 97006, United States
    Neurobiol Aging 28:1286-95. 2007
    ..Taken together, these data suggest that age-related decreases in excitatory orexin innervation to the noradrenergic LC may contribute to the etiology of poor sleep quality in the elderly...
  17. ncbi Effect of age and caloric restriction on circadian adrenal steroid rhythms in rhesus macaques
    Jodi L Downs
    Division of Neuroscience, Oregon National Primate Research Center, Beaverton, OR 97006, USA
    Neurobiol Aging 29:1412-22. 2008
    ..Apart from the partial attenuation of the age-related cortisol elevation in the old males, 24-h adrenal steroid rhythms did not benefit from late-onset CR...
  18. ncbi Evidence for circadian regulation of activating transcription factor 5 but not tyrosine hydroxylase by the chromaffin cell clock
    Dario R Lemos
    Division of Neuroscience, Oregon National Primate Research Center, 505 Northwest 185th Avenue, Beaverton, OR 97006, USA
    Endocrinology 148:5811-21. 2007
    ....
  19. ncbi Glutamate receptor subunit expression in the rhesus macaque locus coeruleus
    Nigel C Noriega
    Division of Neuroscience, Oregon National Primate Research Center, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    Brain Res 1173:53-65. 2007
    ..These data provide a foundation for future examination of how changes in glutamate receptor composition contribute to the control of primate physiology...
  20. ncbi Relative effect of gonadotropin-releasing hormone (GnRH)-I and GnRH-II on gonadotropin release
    Valerie S Densmore
    Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA
    J Clin Endocrinol Metab 88:2126-34. 2003
    ..Taken together, these data show that GnRH-II can potently stimulate gonadotropin release in vivo and that this action is likely mediated through the GnRH-I receptor...
  21. ncbi Neuroendocrine changes in the aging reproductive axis of female rhesus macaques (Macaca mulatta)
    Jodi L Downs
    Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA
    Biol Reprod 75:539-46. 2006
    ....
  22. ncbi Expression profiling of genes encoding glutamate and GABA receptor subunits in three immortalized GnRH cell lines
    Vasilios T Garyfallou
    Division of Neuroscience, Oregon National Primate Research Center, 505 NW 185th Avenue, Beaverton, 97006, USA
    Brain Res 1086:50-4. 2006
    ..Taken together, these data demonstrate comprehensive screening of neurotransmitter receptor genes in a controlled neuronal culture system, and reveal novel features...
  23. ncbi Fasting activates the nonhuman primate hypocretin (orexin) system and its postsynaptic targets
    Sabrina Diano
    Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut, 06520, USA
    Endocrinology 144:3774-8. 2003
    ....
  24. ncbi Developmental changes in the hormonal identity of gonadotroph cells in the rhesus monkey pituitary gland
    Dawud Meeran
    Department of Anatomy, University of Bristol, Bristol BS2 8EJ, United Kingdom
    J Clin Endocrinol Metab 88:2934-42. 2003
    ..Because this morphological switch occurs when marked changes in plasma gonadotrophins are known to occur, it may represent an intrapituitary mechanism that differentially regulates gonadotrophin secretion during sexual development...
  25. ncbi Twenty-four-hour rhythmic gene expression in the rhesus macaque adrenal gland
    Dario R Lemos
    Division of Neuroscience, Oregon National Primate Research Center, 505 Northwest 185th Avenue, Beaverton, Oregon 97006, USA
    Mol Endocrinol 20:1164-76. 2006
    ..Moreover, they strongly imply the existence of an intrinsic circadian clock...

Research Grants18

  1. Interacting Impact of Adrenal and Ovarian Aging on the CNS
    HENRYK URBANSKI; Fiscal Year: 2009
    ..By elucidating the interacting impact of declining ovarian and adrenal steroids on CNS function, we expect to lay a foundation for the development of therapies for many aging-associated disorders in women. ..
  2. Interacting Impact of Adrenal and Ovarian Aging on the CNS
    HENRYK URBANSKI; Fiscal Year: 2009
    ....
  3. Interacting Impact of Adrenal and Ovarian Aging on the CNS
    HENRYK URBANSKI; Fiscal Year: 2007
    ..By elucidating the interacting impact of declining ovarian and adrenal steroids on CNS function, we expect to lay a foundation for the development of therapies for many aging-associated disorders in women. ..
  4. Motor Function and Cognitive Decline in Aging Primates
    HENRYK URBANSKI; Fiscal Year: 2007
    ..Moreover, the data will be of immediate relevance and value to clinical collaborators at OHSU, who are planning the development and implementation of related human studies, as well as others studying human cognitive aging. ..
  5. Postnatal Development of Ionotropic Glutamate Receptors
    HENRYK URBANSKI; Fiscal Year: 2006
    ..g., permeability to Ca2+), elucidation of the mechanisms that regulate their developmental expression should help to lay a foundation for the development of pharmacological treatments for pediatric neurological disorders. ..
  6. Effect of Aging and Caloric Restriction on Circadian Ph*
    HENRYK URBANSKI; Fiscal Year: 2005
    ....
  7. Interacting Impact of Adrenal and Ovarian Aging on the CNS
    Henryk F Urbanski; Fiscal Year: 2010
    ..By elucidating the interacting impact of declining ovarian and adrenal steroids on CNS function, we expect to lay a foundation for the development of therapies for many aging-associated disorders in women. ..