Research Topics
| Erick H TurnerSummaryAffiliation: Oregon Health and Science University Country: USA Publications
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Publications
A taxpayer-funded clinical trials registry and results databaseErick H Turner
PLoS Med 1:e60. 2004
Publication bias in antipsychotic trials: an analysis of efficacy comparing the published literature to the US Food and Drug Administration databaseErick H Turner
Department of Psychiatry, Oregon Health and Science University, Portland, Oregon, USA
PLoS Med 9:e1001189. 2012..Thus one may determine whether publication bias is present and quantify the extent to which it inflates apparent drug efficacy...
Selective publication of antidepressant trials and its influence on apparent efficacyErick H Turner
Department of Psychiatry, Oregon Health and Science University, Portland, OR, USA
N Engl J Med 358:252-60. 2008..Selective publication of clinical trials--and the outcomes within those trials--can lead to unrealistic estimates of drug effectiveness and alter the apparent risk-benefit ratio...
Strategies to decrease costs of prescribing selective serotonin reuptake inhibitors at a VA Medical CenterSteven K Dobscha
Portland Veterans Affairs Medical Center, Oregon 97207, USA
Psychiatr Serv 54:195-200. 2003..The authors examined the efficacy of a multifaceted intervention designed to contain the cost of prescribing selective serotonin reuptake inhibitors (SSRIs) to inpatients and outpatients served by a Veterans Affairs (VA) medical center...
5-Hydroxytryptophan plus SSRIs for interferon-induced depression: synergistic mechanisms for normalizing synaptic serotoninErick H Turner
Mental Health Division, Mood Disorders Research Center, Portland VA Medical Center, 3710 SW US Veterans Hospital Rd, Portland, OR 97239, USA
Med Hypotheses 65:138-44. 2005..Several double-blind studies have shown 5-HTP to be effective in the treatment of nondrug-induced depression. We hypothesize that patients who become depressed on IFN will respond to the synergistic combination of SSRIs plus 5-HTP...
Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophanErick H Turner
Mood Disorders Center, Portland VA Medical Center, Portland, OR 97239, USA
Pharmacol Ther 109:325-38. 2006..Safety issues with 5-HTP are also reviewed, with emphasis on eosinophilia myalgia syndrome (EMS) and serotonin syndrome...
Closing a loophole in the FDA Amendments ActErick H Turner
Science 322:44-6. 2008
Efficacy of antidepressantsErick H Turner
BMJ 336:516-7. 2008
Posting FDA new drug application reviewsErick H Turner
JAMA 298:863-4. 2007
Double-blind, placebo-controlled study of single-dose metergoline in depressed patients with seasonal affective disorderErick H Turner
Section on Biological Rhythms, Intramural Research Program, National Institute of Mental Health, Bethesda, Maryland, USA
J Clin Psychopharmacol 22:216-20. 2002..These data suggest that single doses of metergoline may have antidepressant effects that last several days. Possible mechanisms include 5-hydroxytryptamine(2) receptor downregulation and dopamine agonism...
