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Species | Maret TraberSummaryAffiliation: Oregon State University Country: USA Publications
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Publications
Vitamin E regulatory mechanismsMaret G Traber
Department of Nutrition and Exercise Science, Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Annu Rev Nutr 27:347-62. 2007..As a result of these various mechanisms, liver alpha-tocopherol and other vitamin E concentrations are closely regulated; thus, any potential adverse vitamin E effects are limited...
α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymesMaret G Traber
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Free Radic Biol Med 51:2031-40. 2011..Thus, an overload of hepatic α-tocopherol increases its own metabolism and increases expression of genes of transporters that are postulated to lead to increased excretion of both vitamin E and its metabolites...- Vitamin E regulationMaret G Traber
Linus Pauling Institute, Oregon State University Corvallis, Oregon 97331, USA
Curr Opin Gastroenterol 21:223-7. 2005..This review describes these regulatory mechanisms... 
Vitamin E revisited: do new data validate benefits for chronic disease prevention?Maret G Traber
Linus Pauling Institute, Oregon State University, Corvallis, Oregon 97331, USA
Curr Opin Lipidol 19:30-8. 2008..Vitamin E benefits in human health and chronic disease prevention are evaluated with respect to established alpha-tocopherol functions during vitamin E deficiency, adequacy, and excess...- Vitamin E, antioxidant and nothing moreMaret G Traber
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331 6512, USA
Free Radic Biol Med 43:4-15. 2007.... - Vitamin E traffickingMaret G Traber
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331 6512, USA
Ann N Y Acad Sci 1031:1-12. 2004..Clearly, critical information is lacking in our understanding of the mechanism by which alpha-TTP facilitates the preferential enrichment of VLDLs with alpha-tocopherol... - Heart disease and single-vitamin supplementationMaret G Traber
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Am J Clin Nutr 85:293S-299S. 2007..It is noteworthy that in most trials, biomarkers were not used nor were oxidative stress and lipid peroxidation markers used or plasma vitamin E concentrations measured... - Relationship of vitamin E metabolism and oxidation in exercising human subjectsMaret G Traber
Department of Nutrition and Exercise Sciences, Linus Pauling Institute, Oregon State University, Corvallis, OR 97331 6512, USA
Br J Nutr 96:S34-7. 2006..These results suggest that the mechanism of oxidative damage is operating independently of the inflammatory and muscle damage responses... - Burn and smoke inhalation injury in sheep depletes vitamin E: kinetic studies using deuterated tocopherolsM G Traber
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Free Radic Biol Med 42:1421-9. 2007..These findings suggest that alpha-tocopherol should be administered to burn patients to prevent vitamin E depletion and to protect against oxidative stress from burn injury... - Vitamin E, nuclear receptors and xenobiotic metabolismMaret G Traber
Linus Pauling Institute, Oregon State University, Corvallis, 97331 6512, USA
Arch Biochem Biophys 423:6-11. 2004..Vitamin E acting as a PXR ligand could alter these PXR-mediated reactions. Unfortunately, the extent to which pharmacologic doses of vitamin E modulate these pathways in vivo has not been determined... - Vitamin E and K interactions--a 50-year-old problemMaret G Traber
Linus Pauling Institute, Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis, Oregon 97331, USA
Nutr Rev 66:624-9. 2008.... - Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null miceMaret G Traber
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331 6512, USA
J Nutr Biochem 21:1193-9. 2010..Since they did have higher hepatic α-CEHC concentrations, these data suggest metabolism was up-regulated in the AhR-null mice in order to maintain the hepatic tocopherol concentrations similar to those of wild-type mice... - α-Tocopherol adipose tissue stores are depleted after burn injury in pediatric patientsMaret G Traber
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331 6512, USA
Am J Clin Nutr 92:1378-84. 2010..Adipose tissue α-tocopherol concentrations are generally accepted to reflect long-term vitamin E status... - Vitamins C and E: beneficial effects from a mechanistic perspectiveMaret G Traber
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Free Radic Biol Med 51:1000-13. 2011..Mechanism-based effects of vitamin C and E supplementation on biomarkers and on clinical outcomes from randomized, placebo-controlled trials are emphasized in this review... - Regulation of xenobiotic metabolism, the only signaling function of alpha-tocopherol?Maret G Traber
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Mol Nutr Food Res 54:661-8. 2010..We suggest that the most relevant cytochrome P450-mediated pathway is the one that is most important for the regulation and activation of vitamin K, specifically the one dependent on CYP4F2... - Antioxidant supplementation prevents exercise-induced lipid peroxidation, but not inflammation, in ultramarathon runnersAngela Mastaloudis
Departments of Exercise and Sport Science, Oregon State University, Corvallis, OR 97731, USA
Free Radic Biol Med 36:1329-41. 2004..03). Markers of inflammation were increased dramatically in response to the run regardless of treatment group. Thus, AO supplementation prevented endurance exercise-induced lipid peroxidation but had no effect on inflammatory markers... - Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol dietsMaret G Traber
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331 6512, USA
Free Radic Biol Med 38:773-85. 2005..These data support the hypothesis that alpha-tocopherol modulates xenobiotic metabolism by increasing Cyp3a expression, gamma-CEHC formation, and the excretion of both gamma-tocopherol and gamma-CEHC... - Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementationRichard S Bruno
Linus Pauling Institute, 571 Weniger Hall, Oregon State University, Corvallis, OR 97331, USA
Free Radic Biol Med 40:689-97. 2006.... - Alpha-tocopherol regulation of hepatic cytochrome P450s and ABC transporters in ratsDebbie J Mustacich
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Free Radic Biol Med 41:1069-78. 2006..Thus hepatic alpha-tocopherol concentrations altered hepatic proteins involved in metabolism and disposition of xenobiotic agents... - Dietary zinc restriction and repletion affects DNA integrity in healthy menYang Song
Department of Nutrition and Exercise Sciences and Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Am J Clin Nutr 90:321-8. 2009..Zinc plays an important role in antioxidant defense and the maintenance of cellular DNA integrity. However, no experimental human studies have been performed to examine the role of zinc status on DNA damage... - Lower plasma alpha-carboxyethyl-hydroxychroman after deuterium-labeled alpha-tocopherol supplementation suggests decreased vitamin E metabolism in smokersRichard S Bruno
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Am J Clin Nutr 81:1052-9. 2005..Consequently, evaluating the molecular mechanism or mechanisms responsible for tocopherol metabolism under conditions of oxidative stress and the mechanisms that regulate alpha-tocopherol status is warranted... - Incorporation of deuterated RRR- or all-rac-alpha-tocopherol in plasma and tissues of alpha-tocopherol transfer protein--null miceScott W Leonard
Linus Pauling Institute, Oregon State University, Corvallis, USA
Am J Clin Nutr 75:555-60. 2002..36:1 RRR-alpha-tocopherol to all-rac-alpha-tocopherol. CONCLUSION: Deletion of the alpha-TTP gene in mice results in an accumulation of dietary alpha-tocopherol in the liver and depletion of peripheral tissue alpha-tocopherol... - Alpha-tocopherol modulates genes involved in hepatic xenobiotic pathways in miceDebbie J Mustacich
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
J Nutr Biochem 20:469-76. 2009.... - Vitamins C and E improve regrowth and reduce lipid peroxidation of blackberry shoot tips following cryopreservationEsther E Uchendu
Department of Horticulture, Oregon State University, Corvallis, OR 97331 7304, USA
Plant Cell Rep 29:25-35. 2010..This is the first report of the application of vitamins for improving cryopreservation of plant tissues by minimizing oxidative damage... - Endurance exercise results in DNA damage as detected by the comet assayAngela Mastaloudis
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Free Radic Biol Med 36:966-75. 2004..Thus, endurance exercise resulted in DNA damage as shown by the comet assay and AO seemed to enhance recovery in women but not in men... - Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanesAlan W Taylor
Linus Pauling Institute, Oregon State University, Corvallis, 97331, USA
Anal Biochem 350:41-51. 2006..Ours is the first validated quantitative assay using HPLC-tandem MS applied to plasma total 15-PGFs... - Quantitation of plasma total 15-series F(2)-isoprostanes by sequential solid phase and liquid-liquid extractionAlan W Taylor
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Anal Biochem 396:319-21. 2010..Both changes increased the overall sensitivity of the assay. MS/MS analysis served to confirm the identity of specific peaks that may be better biomarkers than the commonly measured 8-iso-PGF(2alpha)... - Alpha-tocopherol beta-oxidation localized to rat liver mitochondriaDebbie J Mustacich
Linus Pauling Institute, 571 Weniger Hall, Oregon State University, Corvallis, OR 97331, USA
Free Radic Biol Med 48:73-81. 2010..An unexpected finding was that alpha-CEHC, the end product of alpha-tocopherol metabolism, was found almost exclusively in mitochondria. These data are the first to indicate a mitochondrial role in alpha-tocopherol metabolism... - Regulation of the alpha-tocopherol transfer protein in mice: lack of response to dietary vitamin E or oxidative stressDeborah L Bella
Linus Pauling Institute, Oregon State University, Corvallis, Oregon 97331 6512, USA
Lipids 41:105-12. 2006..Thus, hepatic TTP concentrations may be at sufficient levels such that they are unaffected by either modulations of dietary vitamin E or by the conditions of environmentally related oxidative stress used in the present studies... - Regulatory mechanisms to control tissue alpha-tocopherolDebbie J Mustacich
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Free Radic Biol Med 43:610-8. 2007..88, p<0.05). Increased lung MDR1 may provide protection from exposure to environmental toxins by increasing alveolar space alpha-tocopherol... - Women and smokers have elevated urinary F(2)-isoprostane metabolites: a novel extraction and LC-MS methodologyAlan W Taylor
Linus Pauling Institute, Oregon State University, Corvallis, OR, 97331 6512, USA
Lipids 43:925-36. 2008..05). Thus, our method simultaneously allows measurement of urinary F(2)-IsoPs and their metabolites for the determination of oxidative stress... - Human vitamin E requirements assessed with the use of apples fortified with deuterium-labeled alpha-tocopheryl acetateRichard S Bruno
Department of Food Science and Technology, Oregon State University, Corvallis, OR 97331, USA
Am J Clin Nutr 83:299-304. 2006..These estimates support the current human vitamin E requirements despite the claims that the median amount of vitamin E that Americans consume is 7 mg/d... - Cigarette smoke alters human vitamin E requirementsRichard S Bruno
Linus Pauling Institute, Oregon State University, Corvallis, Oregon, USA
J Nutr 135:671-4. 2005..Last, the possibility of CEHC as a biomarker of vitamin E status will be assessed as will the question whether smokers have increased dietary requirements of vitamin E... - Antioxidants did not prevent muscle damage in response to an ultramarathon runAngela Mastaloudis
Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis, OR, USA
Med Sci Sports Exerc 38:72-80. 2006..CQ recovered at a faster rate in women than in men. CONCLUSION: Antioxidants appeared to have no effect on exercise-induced increases in muscle damage or recovery, but important sex differences were observed... - Vitamin E supplementation increases circulating vitamin E metabolites tenfold in end-stage renal disease patientsKylie Sherée Smith
Department of Nutrition and Food Management, Oregon State University, Corvallis, Oregon 97331, USA
Lipids 38:813-9. 2003..Importantly, serum vitamin E metabolite concentrations that increased 10-fold within 30 d of supplementation did not increase further, suggesting routes other than urine for removal of metabolites... - Cigarette smoking increases human vitamin E requirements as estimated by plasma deuterium-labeled CEHCScott W Leonard
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Ann N Y Acad Sci 1031:357-60. 2004..d(3)/d(6)-alpha-CEHC ratios were on average 0.29 +/- 0.05, confirming that all-rac-alpha-tocopherol is metabolized more efficiently. CEHC may be a good marker of vitamin E status, and smokers may have an increased vitamin E requirement... - Studies in humans using deuterium-labeled alpha- and gamma-tocopherols demonstrate faster plasma gamma-tocopherol disappearance and greater gamma-metabolite productionScott W Leonard
Linus Pauling Institute, Oregon State University, 571 Weniger Hall, Corvallis, OR 97331, USA
Free Radic Biol Med 38:857-66. 2005..04) in urine. Thus, gamma-tocopherol is rapidly metabolized to gamma-CEHC, and to a greater degree in women than in men, whereas alpha-tocopherol is maintained in the plasma and little is metabolized to alpha-CEHC... - Gene-nutrient interactions exemplified by the alpha-tocopherol content of tissues from alpha-tocopherol transfer protein-null mice fed different dietary vitamin E concentrationsYunsook Lim
Linus Pauling Institute, Oregon State University, 571 Weniger Hall, Corvallis, OR 97331, USA
Ann N Y Acad Sci 1031:328-9. 2004 - Zinc deficiency affects DNA damage, oxidative stress, antioxidant defenses, and DNA repair in ratsYang Song
Department of Nutrition and Exercise Science and 5Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
J Nutr 139:1626-31. 2009..These results suggest interactions among zinc deficiency, DNA integrity, oxidative stress, and DNA repair and suggested a role for zinc in maintaining DNA integrity... - Ascorbylated 4-hydroxy-2-nonenal as a potential biomarker of oxidative stress responseJohn Sowell
Department of Pharmaceutical Sciences, Oregon State University, Corvallis, OR 97331, USA
J Chromatogr B Analyt Technol Biomed Life Sci 827:139-45. 2005..In the present study, we utilize liquid chromatography coupled with tandem mass spectrometry for investigation into the use of a novel compound, ascorbylated 4-hydroxy-2-nonenal, as a potential biomarker of oxidative stress... - Vitamin E delivery to human skin: studies using deuterated alpha-tocopherol measured by APCI LC-MSHeather Vaule
Department of Nutrition and Food Management, Oregon State University, Corvallis, OR 97331, USA
Free Radic Biol Med 36:456-63. 2004..Plasma percentage d3 peaked at day 8, while skin surface lipid percentage d3 increased on average until day 19. Apparently skin employs a mechanism to deliver alpha-tocopherol into skin via lipid secretions... - From animals to humans: evidence linking oxidative stress as a causative factor in muscle atrophyTyler Barker
Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis, OR 97331, USA
J Physiol 583:421-2. 2007 - Vitamin EDebbie J Mustacich
Linus Pauling Institute, Oregon State University, Corvallis, Oregon 97331, USA
Vitam Horm 76:1-21. 2007..It is expected that the continued studies of these regulatory pathways will provide new insights into vitamin E function from which additional human health benefits will evolve... - Effects of vitamin E on cholesterol levels of hypercholesterolemic patients receiving statinsScott W Leonard
Linus Pauling Institute, Oregon State University, 571 Weniger Hall, Corvallis, OR 97331, USA
Am J Health Syst Pharm 64:2257-66. 2007..The effects of vitamin E supplementation on the cholesterol levels of hypercholesterolemic patients receiving statin therapy were studied... - Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administrationScott W Leonard
Linus Pauling Institute, Oregon State University, Corvallis, OR, USA
J Lipid Res 46:1068-75. 2005..Thus, LC-MS can be successfully used to quantitate alpha- and gamma-CEHC in liver samples. These data suggest that in times of excess liver alpha-tocopherol, increased metabolism of alpha-tocopherol to alpha-CEHC occurs... - 5-nitro-gamma-tocopherol increases in human plasma exposed to cigarette smoke in vitro and in vivoScott W Leonard
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Free Radic Biol Med 35:1560-7. 2003..Our results show that LC-MS can be successfully used for NGT quantitation in biologic samples. Importantly, NGT in smokers' plasma suggests that cigarette smoking causes increased nitrosative stress... - Vitamin E bioavailability from fortified breakfast cereal is greater than that from encapsulated supplementsScott W Leonard
Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
Am J Clin Nutr 79:86-92. 2004.... - Vitamin E and transfer proteinsDaisy E Kaempf-Rotzoll
Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan
Curr Opin Lipidol 14:249-54. 2003..SUMMARY: Insights into the regulation of vitamin E transport and metabolism on the cellular level have made enormous advances, showing the complex interplay of influx, trafficking, efflux and metabolism of this crucial antioxidant... - Aerosolized alpha-tocopherol ameliorates acute lung injury following combined burn and smoke inhalation injury in sheepNaoki Morita
Department of Anaesthesiology, The University of Texas Medical Branch, Galveston, Texas 77555-0833, USA
Shock 25:277-82. 2006..Vitamin E nebulization therapy improved the clinical responses to burn and smoke inhalation-induced acute lung injury... - The ABCs of vitamin E and beta-carotene absorptionMaret G Traber
Am J Clin Nutr 80:3-4. 2004 - Absence of VLDL secretion does not affect alpha-tocopherol content in peripheral tissuesKaori Minehira-Castelli
Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, 94158, USA
J Lipid Res 47:1733-8. 2006..We conclude that the absence of VLDL secretion has little effect on the stores of alpha-tocopherol in peripheral tissues, at least in the mouse... - Antioxidant supplementation decreases lipid peroxidation biomarker F(2)-isoprostanes in plasma of smokersMarion Dietrich
Department of Nutritional Sciences, School of Public Health, University of California, 140 Warren Hall, Berkeley, CA 94720 7360, USA
Cancer Epidemiol Biomarkers Prev 11:7-13. 2002..The intake of antioxidants may help prevent smoking-related diseases. Smoking cessation should still be considered the most effective way to prevent smoking-related diseases... - Enhanced inflammatory responses in alpha-tocopherol transfer protein null miceBettina C Schock
Division of Pulmonary and Critical Care Medicine and Center for Comparative Respiratory Biology and Medicine, University of California School of Medicine, Davis, CA 95616, USA
Arch Biochem Biophys 423:162-9. 2004..Taken together, these results demonstrate that alpha-tocopherol is important for proper modulation of inflammatory responses and that sub-optimal alpha-tocopherol concentrations may derange inflammatory-immune responses... - Vitamins E and C are safe across a broad range of intakesJohn N Hathcock
Council for Responsible Nutrition, Washington, DC, USA
Am J Clin Nutr 81:736-45. 2005.... - Severe vitamin E deficiency modulates airway allergic inflammatory responses in the murine asthma modelYunsook Lim
Department of Internal Medicine, Center for Comparative Lung Biology and Disease, School of Medicine, Davis, CA 95616, USA
Free Radic Res 42:387-96. 2008..It is concluded that the initial stimulation of immune responses by the TTP(-/-) mice were generally blunted compared to the TTP(+/+) mice, thus diminishing some aspects of subsequent allergic inflammatory processes... - Gamma-tocopherol, the new vitamin E?Sridevi Devaraj
Am J Clin Nutr 77:530-1. 2003 - Gamma-tocopherol supplementation alone and in combination with alpha-tocopherol alters biomarkers of oxidative stress and inflammation in subjects with metabolic syndromeSridevi Devaraj
Laboratory for Atherosclerosis and Metabolic Research, Department of Pathology and Laboratory Medicine, UC Davis Medical Center, Sacramento, CA 95817, USA
Free Radic Biol Med 44:1203-8. 2008.... - Vitamin E attenuates acute lung injury in sheep with burn and smoke inhalation injuryNaoki Morita
The University of Texas Medical Branch, Department of Anaesthesiology and Shriners Burns Hospital for Children, Galveston, Texas, USA
Redox Rep 11:61-70. 2006..CONCLUSIONS: Pretreatment with vitamin E ameliorated the acute lung injury caused by burn and smoke inhalation exposure... - Alpha-tocopherol transfer protein deficiency in mice causes multi-organ deregulation of gene networks and behavioral deficits with ageKishorchandra Gohil
Center for Comparative Respiratory and Medicine, Department of Internal Medicine, University of California, Davis, CA 95616, USA
Ann N Y Acad Sci 1031:109-26. 2004..In conclusion, gene-expression profiling studies have identified novel alpha-T-modulated genes and cells in the CNS that may be causatively linked with delayed neurodegeneration and age-related decline in behavioral repertoires... - Dietary zinc restriction in rats alters antioxidant status and increases plasma F2 isoprostanesRichard S Bruno
Department of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA
J Nutr Biochem 18:509-18. 2007..Collectively, zinc deficiency increased oxidative stress, which may be partially explained by increased CYP activity and reductions in hepatic alpha-tocopherol and gamma-tocopherol and in plasma uric acid... - How much vitamin E? ... Just enough!Maret G Traber
Am J Clin Nutr 84:959-60. 2006 - Lactating sows and suckling piglets preferentially incorporate RRR- over all-rac-alpha-tocopherol into milk, plasma and tissuesCharlotte Lauridsen
Department of Animal Nutrition and Physiology, Research Centre Foulum, DK 8830 Tjele, Denmark
J Nutr 132:1258-64. 2002.... - Smoking and exposure to environmental tobacco smoke decrease some plasma antioxidants and increase gamma-tocopherol in vivo after adjustment for dietary antioxidant intakesMarion Dietrich
School of Public Health, University of California, Berkeley 94720 7360, USA
Am J Clin Nutr 77:160-6. 2003..Free radicals in cigarette smoke may cause oxidative damage to macromolecules, contributing to cardiovascular diseases and cancer. Decreased plasma antioxidant concentrations may indicate cigarette smoke-related oxidative stress... - Consumption of sesame oil muffins decreases the urinary excretion of gamma-tocopherol metabolites in humansJan Frank
Department of Food Science, Swedish University of Agricultural Sciences, Box 7051, 750 07 Uppsala, Sweden
Ann N Y Acad Sci 1031:365-7. 2004..In conclusion, a single dose of sesame oil, containing 136 mg sesame lignans (sesamin and sesamolin), reduces the urinary excretion of co-administered gamma-T in humans... - {alpha}-Tocopherol disappearance is faster in cigarette smokers and is inversely related to their ascorbic acid statusRichard S Bruno
Department of Human Nutrition, The Ohio State University, Columbus, OH, USA
Am J Clin Nutr 81:95-103. 2005..Thus, smokers have an increased requirement for both alpha-tocopherol and ascorbic acid... - Gene expression profile of oxidant stress and neurodegeneration in transgenic mice deficient in alpha-tocopherol transfer proteinKishorchandra Gohil
Center for Comparative Respiratory and Medicine, Department of Internal Medicine, University of California, Davis, CA 95616, USA
Free Radic Biol Med 35:1343-54. 2003..The repression of specific genes that determine synaptic plasticity and neuronal development may account for suppressed electrophysiological activities of cortex and impaired behavior in Ttpa(-/-) mice... - Sex differences in the inhibition of gamma-tocopherol metabolism by a single dose of dietary sesame oil in healthy subjectsJan Frank
Department of Food Science, Swedish University of Agricultural Sciences, Uppsala, Sweden
Am J Clin Nutr 87:1723-9. 2008..Gamma-tocopherol has unique properties that may be beneficial in sustaining optimal human health, but hepatic vitamin E metabolism enhances gamma-tocopherol turnover... - gamma-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injuryAtsumori Hamahata
University of Texas Medical Branch, Galveston, TX 77555, USA
Free Radic Biol Med 45:425-33. 2008..Pulmonary gT delivery along with a FO source may be a novel effective treatment strategy in management of patients with acute lung injury... - A simple assay for frequency of chromosome breaks and loss (micronuclei) by flow cytometry of human reticulocytesTal Offer
Nutritional Genomics Center, Children's Hospital of Oakland Research Institute, Oakland, California 94609, USA
FASEB J 19:485-7. 2005..This method, unlike available micronuclei assays, allows rapid evaluation of a large number of cells and therefore should prove to be useful in monitoring of human populations for genetic damage... - Subcutaneous vitamin E ameliorates liver injury in an in vivo model of steatocholestasisJason S Soden
Pediatric Liver Center and Liver Transplantation Program, Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Colorado at Denver Health Sciences Center, Denver, CO, USA
Hepatology 46:485-95. 2007..CONCLUSION: Steatosis sensitizes the liver to bile acid-induced necrotic hepatocyte injury, which is responsive to vitamin E therapy... - Does gamma-tocopherol play a role in the primary prevention of heart disease and cancer? A reviewMarion Dietrich
Jean Mayer US Department of Agriculture, Human Nutrition Research Center on Aging at Tufts University, Nutritional Epidemiology, Boston, MA 02111, USA
J Am Coll Nutr 25:292-9. 2006..In this article, we review publications on dietary gamma-tocopherol intake, plasma gamma-tocopherol levels, cardiovascular disease and cancer risk in humans... - Genome wide responses of murine lungs to dietary alpha-tocopherolSaji Oommen
Division of Pulmonary and Critical Care, Department of Internal Medicine, Genome and Biomedical Sciences Facility, University of California, Davis, CA 95616, USA
Free Radic Res 41:98-109. 2007..Immunohistochemical analyses of three of the encoded proteins suggest that they are expressed in lung vasculature and alveolar regions. The data suggest that the lung alpha-T status may modulate cytoarchitecture of lungs...
Research Grants
- Vitamin E Requirements in Women,Obese Women and Diabetic Obese WomenMaret G Traber; Fiscal Year: 2010....
- Mechanisms of Vitamin E Function Studied in ZebrafishMaret G Traber; Fiscal Year: 2010..the molecular targets altered by - tocopherol-deficiency in the zebrafish will provide a solid basis for understanding why humans require -tocopherol for reproduction as well as to maintain a healthy nervous system ..
- Mechanisms of Vitamin E Function Studied in ZebrafishMaret Traber; Fiscal Year: 2009..the molecular targets altered by - tocopherol-deficiency in the zebrafish will provide a solid basis for understanding why humans require -tocopherol for reproduction as well as to maintain a healthy nervous system ..
- Alpha-Tocopherol Modulation of Xenobiotic MetabolismMaret Traber; Fiscal Year: 2009..We believe that our findings may well have a significant impact on current self-medication practices of the millions of Americans currently taking prescription drugs and vitamin E supplements. ..
- Alpha-Tocopherol Modulation of Xenobiotic MetabolismMaret Traber; Fiscal Year: 2006....
- Alpha-Tocopherol Modulation of Xenobiotic MetabolismMaret Traber; Fiscal Year: 2007..We believe that our findings may well have a significant impact on current self-medication practices of the millions of Americans currently taking prescription drugs and vitamin E supplements. ..
- Oxidative Stress and Vitamin E RequirementsMaret Traber; Fiscal Year: 2005..These proposed studies will further our goal of understanding the role of vitamin E in the amelioration of oxidative damage in aging and in chronic diseases, such as heart disease, diabetes and cancer. ..
- Antioxidant Supplementation,Oxidative Stress & Enduranc*Maret Traber; Fiscal Year: 2002..Finally, the investigators plan to measure markers of inflammatory response, such as C-oxidants increase and vitamin E decreases these markers. ..
- Vitamin E Requirements in Women,Obese Women and Diabetic Obese WomenMaret G Traber; Fiscal Year: 2010....