Research Topics
Species | Michelle A TanchuckSummaryAffiliation: Oregon Health and Science University Country: USA Publications
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Detail Information
Publications
Selected line difference in the effects of ethanol dependence and withdrawal on allopregnanolone levels and 5alpha-reductase enzyme activity and expressionMichelle A Tanchuck
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
Alcohol Clin Exp Res 33:2077-87. 2009....
Assessment of GABA-B, metabotropic glutamate, and opioid receptor involvement in an animal model of binge drinkingMichelle A Tanchuck
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
Alcohol 45:33-44. 2011..MPEP (10 mg/kg) significantly decreased binge alcohol consumption and sucrose self-administration. These results indicate that manipulation of the opioidergic, glutamatergic, and GABAergic systems significantly decreased binge drinking...
The neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in miceKatherine R Gililland-Kaufman
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
Brain Res 1243:113-23. 2008....
Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant miceEthan H Beckley
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, USA
Neuropharmacology 54:365-74. 2008....
Localization of brain 5α-reductase messenger RNA in mice selectively bred for high chronic alcohol withdrawal severityCharles E Roselli
Department of Physiology and Pharmacology, Oregon Health and Science University, Portland, OR 97239, USA
Alcohol 45:763-72. 2011..These results suggest that local Srd5a1 mRNA expression in WSP brain may not change in parallel with local ALLO content or withdrawal severity...
Effects of finasteride on chronic and acute ethanol withdrawal severity in the WSP and WSR selected linesRebecca E Gorin
Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, Portland, Oregon 97239, USA
Alcohol Clin Exp Res 29:939-48. 2005..Using the Withdrawal Seizure-Prone (WSP) and Withdrawal Seizure-Resistant (WSR) selected lines, in the present studies we examined the effect of finasteride on acute and chronic EtOH withdrawal severity...
Increased drinking during withdrawal from intermittent ethanol exposure is blocked by the CRF receptor antagonist D-Phe-CRF(12-41)Deborah A Finn
Portland Alcohol Research Center, Oregon Health and Science University, Portland, Oregon Veterans Affairs Medical Center, Oregon, USA
Alcohol Clin Exp Res 31:939-49. 2007..The present studies provide additional behavioral validation and initial pharmacological validation of this withdrawal-associated drinking procedure...
"Binge" drinking experience in adolescent mice shows sex differences and elevated ethanol intake in adulthoodMoriah N Strong
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
Horm Behav 58:82-90. 2010..Thus, adolescent binge drinking significantly increased unlimited ethanol intake during adulthood, with female mice more susceptible to this effect...
Interaction of chronic ethanol exposure and finasteride: sex and strain differencesDeborah A Finn
Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, VAMC Research R and D 49, 3710 SW U S Veterans Hospital Road, Portland, OR 97239, USA
Pharmacol Biochem Behav 78:435-43. 2004..Finasteride pretreatment significantly decreased blood EtOH concentration (BEC) upon initiation of withdrawal, suggesting that finasteride may affect withdrawal severity via an alteration in EtOH pharmacokinetics...
