Jan M Spitsbergen

Summary

Affiliation: Oregon State University
Country: USA

Publications

  1. doi request reprint Epizootic neoplasia of the lateral line system of lake trout (Salvelinus namaycush) in New York's Finger Lakes
    J M Spitsbergen
    Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Vet Pathol 50:418-33. 2013
  2. doi request reprint Neoplasia and neoplasm-associated lesions in laboratory colonies of zebrafish emphasizing key influences of diet and aquaculture system design
    Jan M Spitsbergen
    Department of Microbiology, Oregon State University, Corvallis, OR 97331, USA
    ILAR J 53:114-25. 2012
  3. pmc Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafish
    Bensheng Ju
    Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    Mol Cancer 8:40. 2009
  4. pmc The state of the art of the zebrafish model for toxicology and toxicologic pathology research--advantages and current limitations
    Jan M Spitsbergen
    Department of Environmental and Molecular Toxicology and Marine Freshwater Biomedical Sciences Center, Oregon State University, Corvallis, Oregon 97333, USA
    Toxicol Pathol 31:62-87. 2003
  5. pmc Finfish and aquatic invertebrate pathology resources for now and the future
    Jan M Spitsbergen
    Center for Fish Disease Research, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Comp Biochem Physiol C Toxicol Pharmacol 149:249-57. 2009
  6. pmc Recommendations for control of pathogens and infectious diseases in fish research facilities
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Comp Biochem Physiol C Toxicol Pharmacol 149:240-8. 2009
  7. doi request reprint Luna stain, an improved selective stain for detection of microsporidian spores in histologic sections
    Tracy S Peterson
    Department of Microbiology, Oregon State University, 220 Nash Hall, Corvallis, Oregon 97331, USA
    Dis Aquat Organ 95:175-80. 2011
  8. pmc Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study
    George S Bailey
    Department of Environmental and Molecular Toxicology, Marine and Freshwater Biomedical Sciences Center, Linus Pauling Institute, Environmental Health Sciences Center, Oregon State University, Corvallis, Oregon 97331, USA
    Chem Res Toxicol 22:1264-76. 2009
  9. ncbi request reprint Pseudocapillaria tomentosa, a nematode pathogen, and associated neoplasms of zebrafish (Danio rerio) kept in research colonies
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, Oregon State University, Corvallis 97331 3804, USA
    Comp Med 52:354-8. 2002
  10. ncbi request reprint Tissue-specific expression of AHR2, ARNT2, and CYP1A in zebrafish embryos and larvae: effects of developmental stage and 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure
    Eric A Andreasen
    Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53705, USA
    Toxicol Sci 68:403-19. 2002

Research Grants

Collaborators

Detail Information

Publications10

  1. doi request reprint Epizootic neoplasia of the lateral line system of lake trout (Salvelinus namaycush) in New York's Finger Lakes
    J M Spitsbergen
    Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Vet Pathol 50:418-33. 2013
    ..A hereditary component, however, may have contributed to this syndrome since only fish of the Seneca Lake strain were affected...
  2. doi request reprint Neoplasia and neoplasm-associated lesions in laboratory colonies of zebrafish emphasizing key influences of diet and aquaculture system design
    Jan M Spitsbergen
    Department of Microbiology, Oregon State University, Corvallis, OR 97331, USA
    ILAR J 53:114-25. 2012
    ....
  3. pmc Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafish
    Bensheng Ju
    Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    Mol Cancer 8:40. 2009
    ..These results suggest that co-activation of the hedgehog and AKT pathways promote tumorigenesis, and that the binary transgenic approach is a useful tool for studying interaction of oncogenes and oncogenic pathways in zebrafish...
  4. pmc The state of the art of the zebrafish model for toxicology and toxicologic pathology research--advantages and current limitations
    Jan M Spitsbergen
    Department of Environmental and Molecular Toxicology and Marine Freshwater Biomedical Sciences Center, Oregon State University, Corvallis, Oregon 97333, USA
    Toxicol Pathol 31:62-87. 2003
    ..Therefore, to fully utilize the potential of zebrafish as an animal model for understanding human development, disease, and toxicology we must greatly advance our knowledge on zebrafish diseases and pathology...
  5. pmc Finfish and aquatic invertebrate pathology resources for now and the future
    Jan M Spitsbergen
    Center for Fish Disease Research, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Comp Biochem Physiol C Toxicol Pharmacol 149:249-57. 2009
    ....
  6. pmc Recommendations for control of pathogens and infectious diseases in fish research facilities
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Comp Biochem Physiol C Toxicol Pharmacol 149:240-8. 2009
    ..Nevertheless, the goal of documenting, detecting, and excluding pathogens in fish is just as important as in mammalian research models...
  7. doi request reprint Luna stain, an improved selective stain for detection of microsporidian spores in histologic sections
    Tracy S Peterson
    Department of Microbiology, Oregon State University, 220 Nash Hall, Corvallis, Oregon 97331, USA
    Dis Aquat Organ 95:175-80. 2011
    ..Gram stain was superior for the 2 microsporidia from invertebrates: S. mytilovum and the unidentified microsporidian from E. sinensis...
  8. pmc Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study
    George S Bailey
    Department of Environmental and Molecular Toxicology, Marine and Freshwater Biomedical Sciences Center, Linus Pauling Institute, Environmental Health Sciences Center, Oregon State University, Corvallis, Oregon 97331, USA
    Chem Res Toxicol 22:1264-76. 2009
    ..They provide the first experimental estimation in any model of the degree of conservatism that may exist for the EPA default linear assumption for a genotoxic carcinogen...
  9. ncbi request reprint Pseudocapillaria tomentosa, a nematode pathogen, and associated neoplasms of zebrafish (Danio rerio) kept in research colonies
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, Oregon State University, Corvallis 97331 3804, USA
    Comp Med 52:354-8. 2002
    ..e., intestinal carcinomas and mixed malignant neoplasms). Capillarid nematodes may have intermediate or paratenic hosts. Using a laboratory transmission study, we confirmed that the parasite has a direct life cycle...
  10. ncbi request reprint Tissue-specific expression of AHR2, ARNT2, and CYP1A in zebrafish embryos and larvae: effects of developmental stage and 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure
    Eric A Andreasen
    Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53705, USA
    Toxicol Sci 68:403-19. 2002
    ..However, TCDD-induced zfCYP1A expression was not detected in these tissues. Taken together, these results are consistent with the notion that the cardiovascular system is a primary target of TCDD developmental toxicity in zebrafish...

Research Grants1

  1. MUTANT LINES OF ZEBRAFISH HIGHLY SENSITIVE TO NEOPLASIA
    Jan Spitsbergen; Fiscal Year: 2005
    ..These lines of zebrafish will provide an efficient and inexpensive system for development of new treatment and prevention strategies for cancer, and will help identify new genes controlling growth and differentiation. ..