Jan M Spitsbergen

Summary

Affiliation: Oregon State University
Country: USA

Publications

  1. ncbi Neoplasia and neoplasm-associated lesions in laboratory colonies of zebrafish emphasizing key influences of diet and aquaculture system design
    Jan M Spitsbergen
    Department of Microbiology, Oregon State University, Corvallis, OR 97331, USA
    ILAR J 53:114-25. 2012
  2. ncbi Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafish
    Bensheng Ju
    Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    Mol Cancer 8:40. 2009
  3. ncbi The state of the art of the zebrafish model for toxicology and toxicologic pathology research--advantages and current limitations
    Jan M Spitsbergen
    Department of Environmental and Molecular Toxicology and Marine Freshwater Biomedical Sciences Center, Oregon State University, Corvallis, Oregon 97333, USA
    Toxicol Pathol 31:62-87. 2003
  4. ncbi Finfish and aquatic invertebrate pathology resources for now and the future
    Jan M Spitsbergen
    Center for Fish Disease Research, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Comp Biochem Physiol C Toxicol Pharmacol 149:249-57. 2009
  5. ncbi Luna stain, an improved selective stain for detection of microsporidian spores in histologic sections
    Tracy S Peterson
    Department of Microbiology, Oregon State University, 220 Nash Hall, Corvallis, Oregon 97331, USA
    Dis Aquat Organ 95:175-80. 2011
  6. ncbi Recommendations for control of pathogens and infectious diseases in fish research facilities
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Comp Biochem Physiol C Toxicol Pharmacol 149:240-8. 2009
  7. ncbi Pseudocapillaria tomentosa, a nematode pathogen, and associated neoplasms of zebrafish (Danio rerio) kept in research colonies
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, Oregon State University, Corvallis 97331-3804, USA
    Comp Med 52:354-8. 2002
  8. ncbi Tissue-specific expression of AHR2, ARNT2, and CYP1A in zebrafish embryos and larvae: effects of developmental stage and 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure
    Eric A Andreasen
    Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53705, USA
    Toxicol Sci 68:403-19. 2002

Research Grants

  1. MUTANT LINES OF ZEBRAFISH HIGHLY SENSITIVE TO NEOPLASIA
    Jan Spitsbergen; Fiscal Year: 2005

Collaborators

Detail Information

Publications8

  1. ncbi Neoplasia and neoplasm-associated lesions in laboratory colonies of zebrafish emphasizing key influences of diet and aquaculture system design
    Jan M Spitsbergen
    Department of Microbiology, Oregon State University, Corvallis, OR 97331, USA
    ILAR J 53:114-25. 2012
    ....
  2. ncbi Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafish
    Bensheng Ju
    Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    Mol Cancer 8:40. 2009
    ..These results suggest that co-activation of the hedgehog and AKT pathways promote tumorigenesis, and that the binary transgenic approach is a useful tool for studying interaction of oncogenes and oncogenic pathways in zebrafish...
  3. ncbi The state of the art of the zebrafish model for toxicology and toxicologic pathology research--advantages and current limitations
    Jan M Spitsbergen
    Department of Environmental and Molecular Toxicology and Marine Freshwater Biomedical Sciences Center, Oregon State University, Corvallis, Oregon 97333, USA
    Toxicol Pathol 31:62-87. 2003
    ..Therefore, to fully utilize the potential of zebrafish as an animal model for understanding human development, disease, and toxicology we must greatly advance our knowledge on zebrafish diseases and pathology...
  4. ncbi Finfish and aquatic invertebrate pathology resources for now and the future
    Jan M Spitsbergen
    Center for Fish Disease Research, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Comp Biochem Physiol C Toxicol Pharmacol 149:249-57. 2009
    ....
  5. ncbi Luna stain, an improved selective stain for detection of microsporidian spores in histologic sections
    Tracy S Peterson
    Department of Microbiology, Oregon State University, 220 Nash Hall, Corvallis, Oregon 97331, USA
    Dis Aquat Organ 95:175-80. 2011
    ..Gram stain was superior for the 2 microsporidia from invertebrates: S. mytilovum and the unidentified microsporidian from E. sinensis...
  6. ncbi Recommendations for control of pathogens and infectious diseases in fish research facilities
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Comp Biochem Physiol C Toxicol Pharmacol 149:240-8. 2009
    ..Nevertheless, the goal of documenting, detecting, and excluding pathogens in fish is just as important as in mammalian research models...
  7. ncbi Pseudocapillaria tomentosa, a nematode pathogen, and associated neoplasms of zebrafish (Danio rerio) kept in research colonies
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, Oregon State University, Corvallis 97331-3804, USA
    Comp Med 52:354-8. 2002
    ..e., intestinal carcinomas and mixed malignant neoplasms). Capillarid nematodes may have intermediate or paratenic hosts. Using a laboratory transmission study, we confirmed that the parasite has a direct life cycle...
  8. ncbi Tissue-specific expression of AHR2, ARNT2, and CYP1A in zebrafish embryos and larvae: effects of developmental stage and 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure
    Eric A Andreasen
    Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53705, USA
    Toxicol Sci 68:403-19. 2002
    ..However, TCDD-induced zfCYP1A expression was not detected in these tissues. Taken together, these results are consistent with the notion that the cardiovascular system is a primary target of TCDD developmental toxicity in zebrafish...

Research Grants1

  1. MUTANT LINES OF ZEBRAFISH HIGHLY SENSITIVE TO NEOPLASIA
    Jan Spitsbergen; Fiscal Year: 2005
    ..These lines of zebrafish will provide an efficient and inexpensive system for development of new treatment and prevention strategies for cancer, and will help identify new genes controlling growth and differentiation. ..