Amnon Sonnenberg

..A mathematical model has been developed to gain insights into how, after an initial event of upper gastrointestinal bleeding, complications can accumulate in individual patients and expose them to an increased risk of death...

..We used a large database of pathology reports to analyze the geographic distribution of microscopic colitis (MC) and compare it with those of UC and CD...

..We examined long-term time trends in colorectal cancer mortality in 6 European countries to determine when the reduction began...

..Many such environmental risk factors vary potentially with occupational exposure. We used a large national database to study the occupational variation of mortality associated with CD and UC...

..The benefit of repeat colonoscopy in managing delayed postpolypectomy bleeding is unknown. This study aimed to assess the outcome of repeat colonoscopy to achieve hemostasis...

..There is some preliminary evidence to suggest that patients with inflammatory bowel disease (IBD) are less frequently infected with Helicobacter pylori than the general population...

..A large variety of test procedures is available to diagnose and treat patients with suspected gastrointestinal bleeding. The aim of the study was to investigate which test sequence should be utilized in managing gastrointestinal bleeding...

..The present analysis served to address the question at what age environmental factors start to exert their influence on the occurrence of ulcerative colitis...

..The aims of the study were to investigate the seasonal and monthly variations of birth dates among patients with Crohn's disease (CD) and ulcerative colitis (UC)...

..The aim of the present study was to test whether these variations might be related to exacerbations of inflammatory bowel disease secondary to superimposed gastrointestinal infection...

..The aim was to follow the time trends of mortality from ulcerative colitis and compare them with those of gastric and duodenal ulcer...

..The purpose of this study was to analyze physician visits associated with inflammatory bowel disease in the United States in order to shed light on the underlying disease time trends in the United States...

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..The present study served to test whether Crohn's disease and ulcerative colitis showed similarities in the temporal variation of their mortality rates among different countries...

..Physicians with few talents and lots of time to spare will accumulate in administration and politics, whereas those with talents and little time will remain committed to biomedical research or clinical practice...

..The epidemiology of peptic ulcer and inflammatory bowel disease shows many similar patterns. The aim of the present study was to compare the geographic distribution of mortality from peptic ulcer with that from inflammatory bowel disease...

..The aim of the study is to test the usefulness of influence diagrams in resolving conflicts centered on managing complex disease processes...

..As the achievement of perfect health constitutes an unattainable goal, a sequence of gastroenterological interventions should not be continued much further beyond its initial success...

..The study aim is to present a mathematical model of H. pylori epidemiology that explains the peculiar long-term trends of ulcer disease...

..Ultimately, each player tries to outdo the opponent while heading in the wrong direction. Recognizing the hallmarks of the game of prisoner's dilemma may help gastroenterologists to avoid such competitions...

..The amount of surgical sequelae could drop, if surgeons were forced to care for all their own postsurgical syndromes or if surgery entered a joint enterprise with gastroenterology caring for the same patient pool...

..Aim: To describe this phenomenon in terms of decision analysis and characterize the parameters affecting its occurrence...

..These rules enable gastroenterologists to enlighten themselves, as well as their patients, about the future outcome of a given gastrointestinal disease...

..It is frequently difficult to differentiate between a benign and malignant pancreatic mass. The aim of this study was to assess the parameters that affect the decision to perform surgery on a suspicious pancreatic head lesion...

..The aim of the study was to use hospitalization data for the analysis of inflammatory bowel disease time trends in the United States...

..pylori infection. CONCLUSION: The study of environmental risk factors may provide an opportunity to better understand GERD and develop a means of its prevention...

..The probability of achieving cure depends on the interplay between the patient's initial health status and the expected efficacy of the gastroenterological interventions...

..It was hypothesised that the time trends among different ethnic groups would be shaped by similar birth cohort patterns...

..The time trends of gastric and duodenal ulcer disease are shaped by a birth-cohort phenomenon...

..This analysis investigates the clinical parameters that should drive decisions about when to continue or stop the search for an elusive source of gastrointestinal bleeding...

..The purpose was to study the epidemiology of Helicobacter-negative gastritis among a large group of patients with inflammatory bowel disease (IBD) and healthy controls...

..We investigated whether infection with Helicobacter pylori and signs of chronic active gastritis and intestinal metaplasia in gastric biopsy samples were inversely associated with Barrett's metaplasia...

..The risk of dying from gastric cancer appears to have increased among consecutive generations born during the 19th century. Aim: To follow the time trends of hospitalization for gastric cancer and test whether they confirm such increase...

..The aim of this epidemiological study was to follow the time trends of mortality from gastric cancer and compare them with those of gastric and duodenal ulcer...

..The aim of the present study is to introduce a new mathematical model on how to weigh a variety of factors contributing to chronic liver disease by the relevance of their influence on the overall disease processes...

..The Nationwide Inpatient Sample of the Healthcare Cost and Utilization Project (HCUP) was used to study the recent demographic characteristics of patients with Crohn's disease (CD) or ulcerative colitis (UC)...

..The present study used hospital statistics to compare the age distribution of inflammatory bowel disease (IBD) among different countries...

..The study served to assess whether the geographic variation of IBD within the United States might be influenced by C. difficile infection...

..The Nationwide Inpatient Sample (NIS) of the Healthcare Cost and Utilization Project (HCUP) was used to study the demographic characteristics of achalasia patients...

..The Department of Veterans Affairs (VA) is the largest healthcare system in the United States. The VA database was used to analyze patterns of hospitalization for inflammatory bowel disease (IBD) among US military veterans...

..The objective of the analysis was to check whether the time trends of hospitalization would show different patterns among different age groups...

..The term 'ritual' refers to the utilization of an ineffectual intervention with little chances of achieving a medically relevant goal...

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..The study aim was to test whether idiopathic colitis in macaques was associated with any characteristic changes of the gastric mucosa resembling similar changes in humans...

..Testing yields the most reliable results if the test measure falls well within a tester's own level of competence. Test measures outside the tester's competence level lead to tests with worse outcome than no testing at all...

..Although the equilibrium does not provide the individual players with their best possible payoff, it yields the best overall outcome available to both parties given the economic and medical constraints of the situation...

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..Chemoprevention of esophageal adenocarcinoma using nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce the risk of cancer in patients with Barrett's esophagus. The aim of the study was to assess the cost-effectiveness of this strategy...

..The present study aims to analyze the relationships between hope and truth in the decision on how much information to disclose to a patient with severe gastrointestinal disease...

..In all aging medical systems alike, the proportion of process tends to increase at the expense of accomplishment...

..All endoluminal procedures would have to undergo major technological improvements before they could become comparable with fundoplication or antisecretory therapy...

..The physician may then come to realize that standing still and waiting become as effective and less costly than a lengthy circular work-up...

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..Rather than admit failure of disease management, a gastroenterologist could resort to blaming patients for their own medical conditions. Blaming the patient constitutes an easy exit strategy for otherwise unsolvable disease conditions...

..It often appears as if complications arising from gastrointestinal disease and interventional procedures come in 'series' and 'cluster' in individual patients...

..CONCLUSIONS: High-grade dysplasia and esophageal adenocarcinoma seem to stem from an extreme and unfavorable constellation of all risk factors that are generally held responsible for the development of GERD and Barrett's esophagus...

..Esophagectomy for early esophageal adenocarcinoma is associated with increased operative mortality and morbidity, but possibly a decreased recurrence rate compared with endoscopic therapy when using EMR and radiofrequency ablation...

..To study practice patterns in the management of non-obstructive dysphagia among U.S. gastroenterologists...

..Only few data exist on the epidemiology and management of esophageal strictures and rings...

..In conclusion, in patients with compensated cirrhosis and small HCC, a strategy of immediate treatment with either TACE or RFA prevails over a strategy of expectant monitoring with the intention of transplantation...

..The exact timing of the follow-up colonoscopy needs to be determined...

..The aim of this study was to characterize patients who receive endoscopy for dyspepsia and measure predictors of primary endoscopic outcomes, utilizing a large national endoscopic database...

..The aim was too describe the demographic characteristics of patients with inflammatory bowel disease (IBD) undergoing colonoscopy...

..The efficacy of screening and surveillance EGD for esophageal adenocarcinoma (EAC) is controversial...

..The similarity in the monthly fluctuations of both IBD suggests that their incidence or flare-ups may be influenced by identical exogenous risk factors...

..The time trends of neither endoscopic procedures nor endoscopic diagnoses revealed any seasonal variation or other cyclic pattern. CONCLUSIONS: The performance of endoscopic procedures is unaffected by any seasonal variation...

..The objective of this study was to describe the current epidemiology of noncardia gastric cancer (noncardia gastric adenocarcinoma (NCGA)) in the United States...

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..CONCLUSIONS: The study demonstrates that threshold analysis can serve as a simple and convenient instrument to solve a large variety of problems in clinical gastroenterology...

..Because nonattendance of outpatients scheduled for GI endoscopy is unavoidable, a frequently recommended solution involves overbooking patient appointments...

..Patterns of GI endoscopy are influenced by the underlying epidemiology of GI disease, as well as by policy and practice guidelines...

..The aim of the present study was to follow the time trends of mortality from gastric and duodenal ulcer in countries outside Europe and compare them with previous reports of ulcer mortality from Europe and North America...

..Utility starts to decline at MELD scores above 28. 5. The current allocation system (MELD) fails to maximize utility with regard to re-LT...

..Frequently, there is disagreement between consecutive endoscopies about the true number of mucosal lesions...

..The impact of gastro-oesophageal reflux disease on hospitalization is unknown...

..The final recommendations are based on the data available at the time of the production of the document and may be updated with pertinent scientific developments at a later time...

..Gastroenterologists are frequently requested to perform endoscopic procedures to rule out cancer or other serious GI disease before major surgical operations...

..Erosive oesophagitis should be considered especially in patients on NSAIDs who complain of heartburn...

..This lack of association between gastric surgery and Barrett's esophagus suggests that reflux of bile without acid is not sufficient to damage the esophageal mucosa...

..We report on the 20-year follow-up of 2,306 patients with at least two endoscopic examinations who were taking no antisecretory medication before baseline endoscopy and whose long-term treatment was determined by reflux symptoms...

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..A decision analysis is carried out to quantify the counteracting influences of H. pylori and resolve the controversy about a public policy to eliminate H. pylori from the general population...

..The diagnosis and management of Barrett's esophagus (BE) are controversial. We conducted a critical review of the literature in BE to provide guidance on clinically relevant issues...

..Mechanisms in addition to acid reflux must contribute to the development of Barrett's esophagus...

..A single colonoscopy at the age of 65 years has been recommended as a potential option to screen for colorectal cancer. This study compares the cost-effectiveness of 2 screening programs based on a single or repeated colonoscopy...

..i.d.) has minimal effect on pulmonary function, pulmonary medication requirements, or survival, but significantly improves asthma symptoms and overall clinical status...

..The similarity between the time trends of duodenal ulcer and ulcerative colitis suggests the influence of one or more shared risk factors...

..The high complication cost and the lower efficacy of aspirin render screening colonoscopy a more cost-effective strategy to prevent colorectal cancer...

..The aim of this study was to quantify risks and benefits of different screening strategies in elderly patients with varying life expectancies...

..The poor medical history exposes the patient, therefore, to more test-related risks, and prolongs the diagnostic process. All these downsides of a poor history ultimately increase medical resource utilization and healthcare expenditures...

..92, 95% CI = 0.87-0.97). CONCLUSION: Gallstone disease occurs frequently in hospitalized patients with chronic liver disease or liver cirrhosis and contributes to the burden of the disease...

..In conclusion, factors other than exposure of the esophageal mucosa to acid must contribute to the development of erosive esophagitis...

..Final interpretation of a cost-effectiveness analysis relies on whether costs and outcomes in the study can be realized in one's own health care environment...

..There are no significant differences in the incidence of this tumour after medical or surgical therapy of GERD. It is unlikely, however, that arguments will convince proponents of one treatment or another to change their opinions...

..These upper GI symptoms were associated with significant loss of work and activity days...

..The aim of the present study is to develop a mathematical model for quantifying the impact of diagnostic tests on a patient's health-related quality of life (HRQL)...

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