Lisa C Silbert

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Does statin use decrease the amount of Alzheimer disease pathology in the brain?
    Lisa C Silbert
    Neurology 69:E8-11. 2007
  2. pmc Trajectory of white matter hyperintensity burden preceding mild cognitive impairment
    Lisa C Silbert
    Department of Neurology, Oregon Health and Science University, Portland, OR, USA
    Neurology 79:741-7. 2012
  3. pmc Neuroimaging and cognition in Parkinson's disease dementia
    Lisa C Silbert
    Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
    Brain Pathol 20:646-53. 2010
  4. pmc Cognitive impairment risk: white matter hyperintensity progression matters
    Lisa C Silbert
    Layton Aging and Alzheimer s Disease Center, Department of Neurology, CR 131, Oregon Health and Science University, 3181 S W Sam Jackson Park Rd, Portland, OR 97239, USA
    Neurology 73:120-5. 2009
  5. pmc Impact of white matter hyperintensity volume progression on rate of cognitive and motor decline
    L C Silbert
    Layton Aging and Alzheimer s Disease Center, Department of Neurology, CR 131, Oregon Health and Science University, 3181 S W Sam Jackson Park Road, Portland, OR 97201, USA
    Neurology 71:108-13. 2008
  6. ncbi request reprint Cortical excitability and age-related volumetric MRI changes
    L C Silbert
    Department of Neurology, Layton Aging and Alzheimer s Disease Center, Oregon Health and Science University, Portland, OR 97201, USA
    Clin Neurophysiol 117:1029-36. 2006
  7. ncbi request reprint Changes in premorbid brain volume predict Alzheimer's disease pathology
    L C Silbert
    Aging and Alzheimer s Disease Center, Department of Neurology, Oregon Health and Science University, Portland 97201, USA
    Neurology 61:487-92. 2003
  8. pmc Neuropathologic basis of white matter hyperintensity accumulation with advanced age
    Deniz Erten-Lyons
    From the Department of Neurology D E L, J K, L C S, Veterans Affairs Medical Center, Portland, OR and Departments of Neurology D E L, J K, N M, H H D, D B H, K W, L C S and Pathology R W, S G, H T, Oregon Health and Science University, Portland
    Neurology 81:977-83. 2013
  9. pmc Neuropathologic basis of age-associated brain atrophy
    Deniz Erten-Lyons
    Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
    JAMA Neurol 70:616-22. 2013
  10. ncbi request reprint Brain volumes in Guam dementia vs Parkinson dementia complex vs aging Chamorro adults
    J A Kaye
    Departments of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
    Neurology 69:196-9. 2007

Research Grants

Detail Information

Publications14

  1. ncbi request reprint Does statin use decrease the amount of Alzheimer disease pathology in the brain?
    Lisa C Silbert
    Neurology 69:E8-11. 2007
  2. pmc Trajectory of white matter hyperintensity burden preceding mild cognitive impairment
    Lisa C Silbert
    Department of Neurology, Oregon Health and Science University, Portland, OR, USA
    Neurology 79:741-7. 2012
    ..To determine the time of acceleration in white matter hyperintensity (WMH) burden, a common indicator of cerebrovascular pathology, in relation to conversion to mild cognitive impairment (MCI) in the elderly...
  3. pmc Neuroimaging and cognition in Parkinson's disease dementia
    Lisa C Silbert
    Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
    Brain Pathol 20:646-53. 2010
    ....
  4. pmc Cognitive impairment risk: white matter hyperintensity progression matters
    Lisa C Silbert
    Layton Aging and Alzheimer s Disease Center, Department of Neurology, CR 131, Oregon Health and Science University, 3181 S W Sam Jackson Park Rd, Portland, OR 97239, USA
    Neurology 73:120-5. 2009
    ..To determine whether white matter hyperintensity (WMH) progression rate is a better predictor of cognitive impairment risk than baseline WMH volume in healthy elderly individuals...
  5. pmc Impact of white matter hyperintensity volume progression on rate of cognitive and motor decline
    L C Silbert
    Layton Aging and Alzheimer s Disease Center, Department of Neurology, CR 131, Oregon Health and Science University, 3181 S W Sam Jackson Park Road, Portland, OR 97201, USA
    Neurology 71:108-13. 2008
    ....
  6. ncbi request reprint Cortical excitability and age-related volumetric MRI changes
    L C Silbert
    Department of Neurology, Layton Aging and Alzheimer s Disease Center, Oregon Health and Science University, Portland, OR 97201, USA
    Clin Neurophysiol 117:1029-36. 2006
    ..Information regarding cortical excitability in neurologically intact elderly would augment our understanding of the pathophysiology of aging and assist in the interpretation of TMS studies involving elderly subjects...
  7. ncbi request reprint Changes in premorbid brain volume predict Alzheimer's disease pathology
    L C Silbert
    Aging and Alzheimer s Disease Center, Department of Neurology, Oregon Health and Science University, Portland 97201, USA
    Neurology 61:487-92. 2003
    ..To assess whether changes in antemortem MRI brain volume measurements are valid predictors of subsequent Alzheimer disease (AD) pathology...
  8. pmc Neuropathologic basis of white matter hyperintensity accumulation with advanced age
    Deniz Erten-Lyons
    From the Department of Neurology D E L, J K, L C S, Veterans Affairs Medical Center, Portland, OR and Departments of Neurology D E L, J K, N M, H H D, D B H, K W, L C S and Pathology R W, S G, H T, Oregon Health and Science University, Portland
    Neurology 81:977-83. 2013
    ..To determine which vascular pathology measure most strongly correlates with white matter hyperintensity (WMH) accumulation over time, and whether Alzheimer disease (AD) neuropathology correlates with WMH accumulation...
  9. pmc Neuropathologic basis of age-associated brain atrophy
    Deniz Erten-Lyons
    Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
    JAMA Neurol 70:616-22. 2013
    ..This study aims to clarify the neuropathologic correlates of longitudinal brain atrophy...
  10. ncbi request reprint Brain volumes in Guam dementia vs Parkinson dementia complex vs aging Chamorro adults
    J A Kaye
    Departments of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
    Neurology 69:196-9. 2007
    ..Chamorros with a family history of PDC or dementia may have increased brain atrophy, suggesting a hereditary susceptibility to neurodegenerative disorders...
  11. ncbi request reprint Trajectories of brain loss in aging and the development of cognitive impairment
    N E Carlson
    Division of Biostatistics, Department of Public Health and Preventive Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Mail Code CB669 Portland, OR 97239, USA
    Neurology 70:828-33. 2008
    ..The trajectory of this volume loss relative to the timing of the clinical transition to dementia has not been established...
  12. ncbi request reprint Natural history of cognitive decline in the old old
    D B Howieson
    Layton Aging and Alzheimer s Disease Center CR 131, Department of Neurology, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Neurology 60:1489-94. 2003
    ..To prospectively examine the occurrence and outcome of cognitive decline in healthy, community-dwelling elders...
  13. pmc Biomarker progressions explain higher variability in stage-specific cognitive decline than baseline values in Alzheimer disease
    Hiroko H Dodge
    Department of Neurology, Layton Aging and Alzheimer s Disease Center, Oregon Health and Science University, Portland, OR Department of Neurology, University of Michigan, Ann Arbor, MI Michigan Alzheimer s Disease Center, University of Michigan, Ann Arbor, MI Electronic address
    Alzheimers Dement 10:690-703. 2014
    ..It is unknown which commonly used Alzheimer disease (AD) biomarker values-baseline or progression-best predict longitudinal cognitive decline...
  14. ncbi request reprint Peripheral F2-isoprostanes and F4-neuroprostanes are not increased in Alzheimer's disease
    Thomas J Montine
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Ann Neurol 52:175-9. 2002
    ..These results should guide the organization of clinical trials now being planned for patients with Alzheimer's disease...

Research Grants1

  1. White Matter Change and CNS Process in the Elderly
    Lisa Silbert; Fiscal Year: 2008
    ..This application proposes a structured didactic mentorship program for the principal investigator, Dr. Lisa Silbert, to ensure her independence as a clinical investigator at the end of the 5-year award period. [unreadable] [unreadable]..