Research Topics
| Amanda L SharpeSummaryAffiliation: Oregon Health and Science University Country: USA Publications
Research Grants
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Detail Information
Publications
Repeated nicotine injections decrease operant ethanol self-administrationAmanda L Sharpe
Center for the Neurobehavioral Study of Alcohol, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1083, USA
Alcohol 28:1-7. 2002..However, in this model, the findings demonstrate a reduction in drinking, rather than the enhancement that has been shown in findings obtained from other studies...
Ethanol and sucrose self-administration components: effects of drinking historyAmanda L Sharpe
Center for the Neurobehavioral Study of Alcohol, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1083, USA
Alcohol 29:31-8. 2003..Because most consumption of ethanol by human beings is in solutions that contain mixers that alter the taste of the solution, this taste factor needs to be considered in the regulation of ethanol drinking...
Ataxia and c-Fos expression in mice drinking ethanol in a limited access sessionAmanda L Sharpe
Portland Alcohol Research Center, Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97239, USA
Alcohol Clin Exp Res 29:1419-26. 2005..Thus, the goal of this study was to demonstrate ataxia and to examine changes in c-Fos expression in mice after self-administration of intoxicating doses of ethanol...
Mice deficient in corticotropin-releasing factor receptor type 2 exhibit normal ethanol-associated behaviorsAmanda L Sharpe
Department of Behavioral Neuroscience, the Portland Alcohol Research Center, Oregon Health and Science University, and the Research Service, Portland VA Medical Center, Portland, Oregon 97239, USA
Alcohol Clin Exp Res 29:1601-9. 2005..The objective of these studies was to examine the effect of corticotropin-releasing factor receptor type 2 (CRF2) on ethanol consumption, conditioned taste aversion, sedation, and hypothermia...
Corticotropin-releasing factor overexpression decreases ethanol drinking and increases sensitivity to the sedative effects of ethanolAbraham A Palmer
Department of Behavioral Neuroscience, Oregon Health and Science University, 3181 Sam Jackson Park Road, Portland, OR 97239, USA
Psychopharmacology (Berl) 176:386-97. 2004..This difference is associated with greater sensitivity to the sedative-hypnotic effects of EtOH, but not with increased sensitivity to the aversive effects of EtOH...
Ethanol concentration-dependent effects and the role of stress on ethanol drinking in corticotropin-releasing factor type 1 and double type 1 and 2 receptor knockout miceRaul Pastor
Behavioral Neuroscience Department and Portland Alcohol Research Center, Oregon Health and Science University, Portland, OR, USA
Psychopharmacology (Berl) 218:169-77. 2011..CRF(1) play a role in EtOH-induced behavioral neuroadaptation, in binge-like EtOH consumption, and in heightened EtOH consumption in dependent animals...
Central urocortin 3 administration decreases limited-access ethanol intake in nondependent miceAmanda L Sharpe
Department of Behavioral Neuroscience, the Portland Alcohol Research Center, Oregon Health and Science University, Portland, Oregon, USA
Behav Pharmacol 20:346-51. 2009..Food intake at both 2 h and 24 h after injection was statistically unaffected by Ucn 3 administration. These results establish a role for CRF type 2 receptors in a nondependent mouse model of ethanol self-administration...
Proopiomelanocortin peptides are not essential for development of ethanol-induced behavioral sensitizationAmanda L Sharpe
Center for the Study of Weight Regulation and Associated Disorders, Department of Behavioral Neuroscience, Science University, Portland, OR, USA
Alcohol Clin Exp Res 33:1202-7. 2009..This study used a genetically engineered mouse strain that is deficient for neural POMC to directly determine if any POMC peptides are necessary for the development of ethanol-induced locomotor sensitization...
Effect of ethanol self-administration on mu- and delta-opioid receptor-mediated G-protein activityLaura J Sim-Selley
Department of Pharmacology and Toxicology and Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Medical College of Virginia, Richmond 23298, USA
Alcohol Clin Exp Res 26:688-94. 2002..This study examined the effects of ethanol self-administration on mu- and delta-opioid receptor-mediated G-protein activity in specific brain regions of male Long Evans rats...
Research Grants
- Ethanol Intake and Hypothalamic CRH Receptor Type 2AMANDA SHARPE; Fiscal Year: 2005..abstract_text> ..
