Dennis W Schultz

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Lack of an association of apolipoprotein E gene polymorphisms with familial age-related macular degeneration
    Dennis W Schultz
    Casey Eye Institute, Oregon Health and Science University, Portland, 97239, USA
    Arch Ophthalmol 121:679-83. 2003
  2. ncbi request reprint HEMICENTIN-1 (FIBULIN-6) and the 1q31 AMD locus in the context of complex disease: review and perspective
    Dennis W Schultz
    Macular Degeneration Center, Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Boulevard, Portland, OR 97239 4197, U S A
    Ophthalmic Genet 26:101-5. 2005
  3. ncbi request reprint Analysis of the ARMD1 locus: evidence that a mutation in HEMICENTIN-1 is associated with age-related macular degeneration in a large family
    Dennis W Schultz
    Macular Degeneration Center, Casey Eye Institute, Portland, OR 97239 4197, USA
    Hum Mol Genet 12:3315-23. 2003
  4. doi request reprint CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration
    Michael L Klein
    Macular Degeneration Center, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, USA
    Ophthalmology 115:1019-25. 2008
  5. pmc Haplotypes in the complement factor H (CFH) gene: associations with drusen and advanced age-related macular degeneration
    Peter J Francis
    Macular Degeneration Center, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America
    PLoS ONE 2:e1197. 2007
  6. ncbi request reprint The LOC387715 gene, smoking, body mass index, environmental associations with advanced age-related macular degeneration
    Peter J Francis
    Macular Degeneration Center, Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239, USA
    Hum Hered 63:212-8. 2007
  7. ncbi request reprint A novel diagnostic test detects a low frequency of the hemicentin Gln5345Arg variant among Northern Irish age related macular degeneration patients
    Gareth J McKay
    Department of Ophthalmology and Vision Science, Queen s University of Belfast, Belfast, Northern Ireland
    Mol Vis 10:682-7. 2004
  8. ncbi request reprint Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration
    Johanna M Seddon
    Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts New England Medical Center, Boston, MA 02111, USA
    JAMA 297:1793-800. 2007
  9. ncbi request reprint Meta-analysis of genome scans of age-related macular degeneration
    Sheila A Fisher
    Department of Medical and Molecular Genetics, Guy s, King s and St Thomas School of Medicine, King s College London, London SE1 9RT, UK
    Hum Mol Genet 14:2257-64. 2005
  10. pmc Age-related macular degeneration--a genome scan in extended families
    Jacek Majewski
    Laboratory of Statistical Genetics, Rockefeller University, New York, NY, USA
    Am J Hum Genet 73:540-50. 2003

Detail Information

Publications11

  1. ncbi request reprint Lack of an association of apolipoprotein E gene polymorphisms with familial age-related macular degeneration
    Dennis W Schultz
    Casey Eye Institute, Oregon Health and Science University, Portland, 97239, USA
    Arch Ophthalmol 121:679-83. 2003
    ..In addition, the epsilon 2 allele of APOE was reported to be possibly associated with an increased risk of AMD...
  2. ncbi request reprint HEMICENTIN-1 (FIBULIN-6) and the 1q31 AMD locus in the context of complex disease: review and perspective
    Dennis W Schultz
    Macular Degeneration Center, Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Boulevard, Portland, OR 97239 4197, U S A
    Ophthalmic Genet 26:101-5. 2005
    ..The data can be reconciled through proposing both additional variants in HEMICENTIN-1 and a second genetic risk factor for AMD in the region...
  3. ncbi request reprint Analysis of the ARMD1 locus: evidence that a mutation in HEMICENTIN-1 is associated with age-related macular degeneration in a large family
    Dennis W Schultz
    Macular Degeneration Center, Casey Eye Institute, Portland, OR 97239 4197, USA
    Hum Mol Genet 12:3315-23. 2003
    ....
  4. doi request reprint CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration
    Michael L Klein
    Macular Degeneration Center, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, USA
    Ophthalmology 115:1019-25. 2008
    ..To determine if CFH and LOC387715/ARMS2 genotypes influence treatment response to AREDS-type nutritional supplementation with antioxidants and zinc...
  5. pmc Haplotypes in the complement factor H (CFH) gene: associations with drusen and advanced age-related macular degeneration
    Peter J Francis
    Macular Degeneration Center, Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America
    PLoS ONE 2:e1197. 2007
    ..We aimed to better understand the functional role of this gene in the AMD disease process and assess whether it is associated with earlier forms of the disease...
  6. ncbi request reprint The LOC387715 gene, smoking, body mass index, environmental associations with advanced age-related macular degeneration
    Peter J Francis
    Macular Degeneration Center, Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239, USA
    Hum Hered 63:212-8. 2007
    ....
  7. ncbi request reprint A novel diagnostic test detects a low frequency of the hemicentin Gln5345Arg variant among Northern Irish age related macular degeneration patients
    Gareth J McKay
    Department of Ophthalmology and Vision Science, Queen s University of Belfast, Belfast, Northern Ireland
    Mol Vis 10:682-7. 2004
    ..The aim of this study is to develop a rapid diagnostic assay for the detection of this mutation and to evaluate its frequency in a sample of AMD patients...
  8. ncbi request reprint Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration
    Johanna M Seddon
    Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts New England Medical Center, Boston, MA 02111, USA
    JAMA 297:1793-800. 2007
    ..Studies have reported that single-nucleotide polymorphisms in the genes CFH and LOC387715 are associated with age-related macular degeneration (AMD)...
  9. ncbi request reprint Meta-analysis of genome scans of age-related macular degeneration
    Sheila A Fisher
    Department of Medical and Molecular Genetics, Guy s, King s and St Thomas School of Medicine, King s College London, London SE1 9RT, UK
    Hum Mol Genet 14:2257-64. 2005
    ..Several of the regions identified here showed only weak evidence for linkage in the individual studies. These results will help prioritize regions for future positional and functional candidate gene studies in AMD...
  10. pmc Age-related macular degeneration--a genome scan in extended families
    Jacek Majewski
    Laboratory of Statistical Genetics, Rockefeller University, New York, NY, USA
    Am J Hum Genet 73:540-50. 2003
    ..Our study has identified new loci that should be considered in future mapping and mutational analyses of AMD and has strengthened the evidence in support of loci suggested by other studies...
  11. ncbi request reprint Expanded genome scan in extended families with age-related macular degeneration
    Sandra Barral
    Laboratory of Statistical Genetics, Rockefeller University, New York, New York, USA
    Invest Ophthalmol Vis Sci 47:5453-9. 2006
    ..To investigate further the genetic contribution to age-related macular degeneration (AMD), increasing the power of a previous analysis and reproducing the original findings...