Martin A Schreiber

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Determinants of mortality in patients with severe blunt head injury
    Martin A Schreiber
    Department of Surgery, Baylor College of Medicine, Houston, TX, USA
    Arch Surg 137:285-90. 2002
  2. doi request reprint A comparison between patients treated at a combat support hospital in Iraq and a Level I trauma center in the United States
    Martin A Schreiber
    Department of Surgery, Section of Trauma and Critical Care, Oregon Health and Science Univeristy, Portland, OR 97239, USA
    J Trauma 64:S118-21; discussion S121-2. 2008
  3. ncbi request reprint Hemostasis in Operation Iraqi Freedom III
    Martin A Schreiber
    Oregon Health and Science University, Portland, OR 97239, USA
    Surgery 142:S61-6. 2007
  4. doi request reprint Research: questions and answers from academic trauma surgeons
    Martin A Schreiber
    Department of Surgery, Oregon Health and Science University, Portland, Oregon, USA
    J Trauma 64:1113-7; discussion 1117-8. 2008
  5. ncbi request reprint Early predictors of massive transfusion in combat casualties
    Martin A Schreiber
    Department of Surgery, Oregon Health and Science University, Portland, OR 97239, USA
    J Am Coll Surg 205:541-5. 2007
  6. ncbi request reprint Coagulopathy in the trauma patient
    Martin A Schreiber
    Oregon Health and Science University, Portland, Oregon 97239, USA
    Curr Opin Crit Care 11:590-7. 2005
  7. pmc Preclinical trauma studies of recombinant factor VIIa
    Martin A Schreiber
    Oregon Health and Science University, Portland, Oregon, USA
    Crit Care 9:S25-8. 2005
  8. ncbi request reprint Hypercoagulability is most prevalent early after injury and in female patients
    Martin A Schreiber
    Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 58:475-80; discussion 480-1. 2005
  9. ncbi request reprint Damage control surgery
    Martin A Schreiber
    Division of Trauma and Critical Care, Oregon Health and Science University, 3181 SW Sam Jackson Road, Mail Code L223A, Portland, OR 97239, USA
    Crit Care Clin 20:101-18. 2004
  10. ncbi request reprint Military trauma training performed in a civilian trauma center
    Martin A Schreiber
    Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    J Surg Res 104:8-14. 2002

Detail Information

Publications103 found, 100 shown here

  1. ncbi request reprint Determinants of mortality in patients with severe blunt head injury
    Martin A Schreiber
    Department of Surgery, Baylor College of Medicine, Houston, TX, USA
    Arch Surg 137:285-90. 2002
    ..Head injury is the leading cause of traumatic death in the United States...
  2. doi request reprint A comparison between patients treated at a combat support hospital in Iraq and a Level I trauma center in the United States
    Martin A Schreiber
    Department of Surgery, Section of Trauma and Critical Care, Oregon Health and Science Univeristy, Portland, OR 97239, USA
    J Trauma 64:S118-21; discussion S121-2. 2008
    ..This study compared two patient populations treated between December 2004 and November 2005, one from a CSH in Iraq, the other at a civilian Level I trauma center...
  3. ncbi request reprint Hemostasis in Operation Iraqi Freedom III
    Martin A Schreiber
    Oregon Health and Science University, Portland, OR 97239, USA
    Surgery 142:S61-6. 2007
    ..These advances currently are being translated to civilian practice altering the care of the urban patient...
  4. doi request reprint Research: questions and answers from academic trauma surgeons
    Martin A Schreiber
    Department of Surgery, Oregon Health and Science University, Portland, Oregon, USA
    J Trauma 64:1113-7; discussion 1117-8. 2008
    ..This study characterizes current research practices, opinions on research quality, and barriers to academic productivity, expressed by academic trauma surgeons...
  5. ncbi request reprint Early predictors of massive transfusion in combat casualties
    Martin A Schreiber
    Department of Surgery, Oregon Health and Science University, Portland, OR 97239, USA
    J Am Coll Surg 205:541-5. 2007
    ..The purpose of this study was to determine which variables, available early after injury, are associated with MT. We hypothesized that International Normalized Ratio and penetrating mechanism would be predictive...
  6. ncbi request reprint Coagulopathy in the trauma patient
    Martin A Schreiber
    Oregon Health and Science University, Portland, Oregon 97239, USA
    Curr Opin Crit Care 11:590-7. 2005
    ..The purpose of this review is to describe the epidemiology and pathophysiology of coagulopathy after trauma and to discuss novel methods of treating it...
  7. pmc Preclinical trauma studies of recombinant factor VIIa
    Martin A Schreiber
    Oregon Health and Science University, Portland, Oregon, USA
    Crit Care 9:S25-8. 2005
    ..All of the animal models described have provided good safety data and suggest that the use of rFVIIa is not associated with systemic activation of coagulation or microthrombosis of end organs...
  8. ncbi request reprint Hypercoagulability is most prevalent early after injury and in female patients
    Martin A Schreiber
    Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 58:475-80; discussion 480-1. 2005
    ..We hypothesized that hypercoagulability would occur early after injury and that there would be no difference between men and women...
  9. ncbi request reprint Damage control surgery
    Martin A Schreiber
    Division of Trauma and Critical Care, Oregon Health and Science University, 3181 SW Sam Jackson Road, Mail Code L223A, Portland, OR 97239, USA
    Crit Care Clin 20:101-18. 2004
    ..This strategy breaks the bloody vicious cycle and results in improved outcomes. Novel technologies like CAVR and rFVIIa contribute to the effectiveness of damage control...
  10. ncbi request reprint Military trauma training performed in a civilian trauma center
    Martin A Schreiber
    Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    J Surg Res 104:8-14. 2002
    ..In September of 1998 an Army team composed of surgeons, nurses, emergency medical technicians (EMTs), and operating room technicians (OR techs) trained in a civilian level 1 trauma center. This study analyzes the quality of the training...
  11. ncbi request reprint The effect of recombinant factor VIIa on coagulopathic pigs with grade V liver injuries
    Martin A Schreiber
    Michael E DeBakey Department of Surgery, Baylor College of Medicine, University of Texas at Houston, Houston, Texas, USA
    J Trauma 53:252-7; discussion 257-9. 2002
    ....
  12. ncbi request reprint Uncontrolled hemorrhagic shock results in a hypercoagulable state modulated by initial fluid resuscitation regimens
    Gordon M Riha
    Division of Trauma, Critical Care, and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    J Trauma Acute Care Surg 75:129-34. 2013
    ..Our objective was to analyze the effects of initial bolus fluids used in military and civilian settings on coagulation and inflammation in a prospective, randomized, blinded trial of resuscitation of uncontrolled hemorrhage...
  13. pmc A latent class model for defining severe hemorrhage: experience from the PROMMTT study
    Mohammad H Rahbar
    Biostatistics Epidemiology Research Design Core, Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston, Houston, Texas, USA
    J Trauma Acute Care Surg 75:S82-8. 2013
    ..We show how a latent class model could improve the accuracy of identifying the SH patients...
  14. doi request reprint The impact of missing trauma data on predicting massive transfusion
    Amber W Trickey
    Department of Surgery, Inova Fairfax Hospital, Falls Church, Virginia, USA
    J Trauma Acute Care Surg 75:S68-74. 2013
    ..Three blood transfusion prediction models were evaluated using an observational trauma data set with valid missing data...
  15. pmc Application of the Berlin definition in PROMMTT patients: the impact of resuscitation on the incidence of hypoxemia
    Bryce R H Robinson
    Division of Trauma Critical Care, Department of Surgery, College of Medicine, University of Cincinnati, Cincinnati, Ohio 45267, USA
    J Trauma Acute Care Surg 75:S61-7. 2013
    ..Acute lung injury following trauma resuscitation remains a concern despite recent advances. With the use of the PROMMTT study population, the risk of hypoxemia and potential modifiable risk factors are studied...
  16. pmc Do-not-resuscitate orders in trauma patients may bias mortality-based effect estimates: an evaluation using the PROMMTT study
    Charles E Wade
    Center for Translational Injury Research, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Trauma Acute Care Surg 75:S89-96. 2013
    ..We determined the frequency, timing, and impact on mortality-based effect estimates for patients with DNR orders in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study...
  17. pmc Resuscitate early with plasma and platelets or balance blood products gradually: findings from the PROMMTT study
    Deborah J Del Junco
    Center for Translational Injury Research, Division of Acute Care Surgery, Department of Surgery, Medical School, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Trauma Acute Care Surg 75:S24-30. 2013
    ..To differentiate the association of in-hospital mortality with early plasma or platelet transfusion from that with delayed but gradually balanced ratios, we developed a separate analytic approach...
  18. doi request reprint Comparison of the hemostatic efficacy of low-volume lyophilized plasma reconstituted using sterile water, lactated Ringer's, normal saline, and Hextend solutions
    Tim H Lee
    From the Division of Trauma, Critical Care and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon
    J Trauma Acute Care Surg 76:264-1; discussion 271-2. 2014
    ..We compared the physiologic effects of resuscitation using LP reconstituted with sterile water (LP-SW), lactated Ringer's solution (LP-LR), normal saline (LP-NS), and Hextend (LP-Hx)...
  19. pmc Purposeful variable selection and stratification to impute missing Focused Assessment with Sonography for Trauma data in trauma research
    Paul A Fuchs
    Center for Translational Injury Research, Division of Acute Care Surgery, Department of Surgery, Medical School, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Trauma Acute Care Surg 75:S75-81. 2013
    ..Owing to variability in patients' injuries and trauma care, these data are unlikely to be missing completely at random, raising concern for validity when analyses exclude patients with missing values...
  20. pmc Increasing time to operation is associated with decreased survival in patients with a positive FAST examination requiring emergent laparotomy
    Ronald R Barbosa
    From the Trauma Services, Legacy Emanuel Hospital and Health Center, Portland, Oregon 97227, USA
    J Trauma Acute Care Surg 75:S48-52. 2013
    ..This study sought to determine the impact of T-OR on survival in patients with a positive FAST who required emergent laparotomy...
  21. doi request reprint Reproducibility of an animal model simulating complex combat-related injury in a multiple-institution format
    S David Cho
    Division of Trauma and Critical Care, Oregon Health and Science University, Portland, Oregon 97239, USA
    Shock 31:87-96. 2009
    ..A consistent severe injury profile was achieved, after which experimental interventions can be applied. This is the first report of a reproducible multicenter trauma and resuscitation-related animal model...
  22. pmc Prehospital intravenous fluid is associated with increased survival in trauma patients
    David A Hampton
    Division of Trauma, Critical Care and Acute Care Surgery, Department of Surgery, School of Medicine, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    J Trauma Acute Care Surg 75:S9-15. 2013
    ..We hypothesized that receiving any prehospital IVF is associated with increased survival in trauma patients compared with receiving no prehospital IVF...
  23. pmc Clinical and mechanistic drivers of acute traumatic coagulopathy
    Mitchell Jay Cohen
    Division of General Surgery, Department of Surgery, School of Medicine, University of California San Francisco, San Francisco, California, USA
    J Trauma Acute Care Surg 75:S40-7. 2013
    ..The PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study provided a unique opportunity to characterize coagulation and the effects of resuscitation on ATC after severe trauma...
  24. pmc Early resuscitation intensity as a surrogate for bleeding severity and early mortality in the PROMMTT study
    Elaheh Rahbar
    Center for Translational Injury Research, University of Texas Health Science Center at Houston, Houston, Texas, USA
    J Trauma Acute Care Surg 75:S16-23. 2013
    ....
  25. doi request reprint Cryoprecipitate use in the PROMMTT study
    John B Holcomb
    Center for Translational Injury Research, Division of Acute Care Surgery, Department of Surgery, Medical School, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Trauma Acute Care Surg 75:S31-9. 2013
    ..Our objectives were to identify patterns and predictors of cryoprecipitate use and determine whether transfusing cryoprecipitate was associated with improved survival...
  26. doi request reprint Hextend and 7.5% hypertonic saline with Dextran are equivalent to Lactated Ringer's in a swine model of initial resuscitation of uncontrolled hemorrhagic shock
    Gordon M Riha
    Division of Trauma, Critical Care, and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 71:1755-60. 2011
    ....
  27. doi request reprint Specific abbreviated injury scale values are responsible for the underestimation of mortality in penetrating trauma patients by the injury severity score
    Susan E Rowell
    Department of Surgery, Oregon Health and Science University, Portland, Oregon 97227, USA
    J Trauma 71:S384-8. 2011
    ..We hypothesized that the mechanism-based difference in mortality could be attributed to certain ISS ranges and specific AIS values by body region...
  28. doi request reprint Red blood cells accelerate the onset of clot formation in polytrauma and hemorrhagic shock
    Nicholas J Spoerke
    Division of Trauma, Critical Care, and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    J Trauma 69:1054-9; discussion 1059-61. 2010
    ..We aimed to determine the effect of RBCs on clotting parameters by comparing resuscitation regimens containing RBCs and plasma with those containing plasma alone...
  29. doi request reprint Gender-based differences in mortality in response to high product ratio massive transfusion
    Susan E Rowell
    Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 71:S375-9. 2011
    ..This has not been examined independently in women and men. A gender dichotomy in outcome after severe injury is known to exist. This study examined gender-related differences in mortality after high product ratio massive transfusion...
  30. doi request reprint Profoundly abnormal initial physiologic and biochemical data cannot be used to determine futility in massively transfused trauma patients
    Ronald R Barbosa
    Trauma Services, Legacy Emanuel Hospital and Health Center, Portland, Oregon 97227, USA
    J Trauma 71:S364-9. 2011
    ..The purpose of this study was to identify objective data that can be used to identify clinical futility in massively transfused trauma patients to allow for early termination of resuscitative efforts...
  31. doi request reprint Splenectomy leads to a persistent hypercoagulable state after trauma
    Jennifer M Watters
    Department of Surgery, Division of Trauma, Critical Care and Acute Care Surgery, Oregon Health and Science University, Portland, OR, USA
    Am J Surg 199:646-51. 2010
    ..It was hypothesized that splenectomy following trauma results in hypercoagulability...
  32. pmc Transfusion of red blood cells in patients with a prehospital Glasgow Coma Scale score of 8 or less and no evidence of shock is associated with worse outcomes
    Joel Elterman
    Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma Acute Care Surg 75:8-14; discussion 14. 2013
    ..Red blood cell transfusion practices vary, and the optimal hemoglobin for patients with traumatic brain injury has not been established...
  33. doi request reprint Chitosan based advanced hemostatic dressing is associated with decreased blood loss in a swine uncontrolled hemorrhage model
    Nicholas R Kunio
    Department of Surgery, Oregon Health and Science University, Portland, OR, USA
    Am J Surg 205:505-10. 2013
    ..The purpose of this study was to compare standard gauze (SG) and advanced hemostatic dressings in use by military personnel in a no-hold model...
  34. pmc The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time-varying treatment with competing risks
    John B Holcomb
    Center for Translational Injury Research, Division of Acute Care Surgery, Department of Surgery, University of Texas Health Science Center at Houston, 6410 Fannin, Ste 1100, Houston, TX 77030, USA
    JAMA Surg 148:127-36. 2013
    ..To relate in-hospital mortality to early transfusion of plasma and/or platelets and to time-varying plasma:red blood cell (RBC) and platelet:RBC ratios...
  35. doi request reprint The use of lyophilized plasma in a severe multi-injury pig model
    Tim H Lee
    Department of Surgery, Division of Trauma, Critical Care and Acute Care Surgery, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    Transfusion 53:72S-79S. 2013
    ..Lyophilized plasma (LP) provides a logistically superior alternative to fresh frozen plasma (FFP)...
  36. doi request reprint Ketamine-based total intravenous anesthesia versus isoflurane anesthesia in a swine model of hemorrhagic shock
    Michael S Englehart
    Section of Trauma and Surgical Critical Care, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 65:901-8; discussion 908-9. 2008
    ..The purpose of this study was to compare the effects of isoflurane (ISO) and TIVA regimens in a swine grade V liver injury model. We hypothesized that TIVA would result in less hypotension and dysfunctional inflammation than ISO...
  37. ncbi request reprint Correlation of missed doses of enoxaparin with increased incidence of deep vein thrombosis in trauma and general surgery patients
    Scott G Louis
    Trauma Research Institute of Oregon, Oregon Health and Science University, Portland
    JAMA Surg 149:365-70. 2014
    ..Enoxaparin sodium is widely used for deep vein thrombosis (DVT) prophylaxis, yet DVT rates remain high in the trauma and general surgery populations. Missed doses during hospitalization are common...
  38. pmc Waiver of consent in noninterventional, observational emergency research: the PROMMTT experience
    Erin E Fox
    Biostatistics Epidemiology Research Design Core, Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    J Trauma Acute Care Surg 75:S3-8. 2013
    ..The goal of this article was to examine the rationale and tradeoffs of using waiver of consent in PROMMTT...
  39. doi request reprint Use of leukoreduced blood does not reduce infection, organ failure, or mortality following trauma
    Michael S Englehart
    Department of Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Road L223A, Portland, OR 97239, USA
    World J Surg 33:1626-32. 2009
    ..The objective of the present study was to determine the effect of LR blood on morbidity and mortality. We hypothesized that the use of LR blood does not improve outcome in trauma patients...
  40. ncbi request reprint A single bolus of 3% hypertonic saline with 6% dextran provides optimal initial resuscitation after uncontrolled hemorrhagic shock
    Jennifer M Watters
    Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 61:75-81. 2006
    ..This study examined effects of a single bolus of hypertonic saline (HTS) with or without (+/-) dextran (D) after uncontrolled hemorrhage (UH) and determined optimal fluid composition...
  41. ncbi request reprint The influence of sex hormones on coagulation and inflammation in the trauma patient
    Arvin C Gee
    Trauma Critical Care Section, Division of General Surgery, Department of Surgery, Oregan Health and Science University, Portland, Oregan 97239, USA
    Shock 29:334-41. 2008
    ..These findings provide evidence that sex hormone levels in the early posttraumatic period are significantly associated with alterations in the hemostatic and inflammatory response to trauma...
  42. ncbi request reprint Fluid resuscitation increases inflammatory gene transcription after traumatic injury
    Jennifer M Watters
    Oregon Health and Science University, Portland, Oregon, USA
    J Trauma 61:300-8; discussion 308-9. 2006
    ..This study aimed to examine effects of resuscitation with lactated Ringer's (LR) and Hextend (HEX) on the inflammatory response after uncontrolled hemorrhagic shock (UHS)...
  43. ncbi request reprint Thromboelastogram-guided enoxaparin dosing does not confer protection from deep venous thrombosis: a randomized controlled pilot trial
    Scott G Louis
    From the Department of Surgery, Division of Trauma and Acute Care Surgery, Trauma Research Institute of Oregon TRIO S G L, P Y V, G M R, J S B, N R K, S U, J D, M S, Oregon Health and Science University, Portland, Oregon and Department of Surgery, University of Miami School of Medicine E G, Miami, Florida
    J Trauma Acute Care Surg 76:937-42; discussion 942-3. 2014
    ..We hypothesized that using ΔR-guided dosing would result in decreased DVT rates...
  44. ncbi request reprint Management and outcomes of traumatic colon injury in civilian and military patients
    Chitra N Sambasivan
    Division of Trauma, Critical Care and Acute Care Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    Am Surg 77:1685-91. 2011
    ..99) did not differ between the two groups. The CP and MP experience different mechanisms and initial management of colon injury. Ultimately, continuity is restored in the majority of both populations...
  45. doi request reprint A novel highly porous silica and chitosan-based hemostatic dressing is superior to HemCon and gauze sponges
    Michael S Englehart
    Department of Surgery, Trauma Critical Care Section, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 65:884-90; discussion 890-2. 2008
    ..The purpose of this study was to compare the hemostatic properties of a novel highly porous silica and chitosan-based dressing (TraumaStat) to HemCon, and gauze dressing in a severe groin injury model in swine...
  46. ncbi request reprint Lyophilized plasma reconstituted with ascorbic acid suppresses inflammation and oxidative DNA damage
    Philbert Y Van
    Department of Surgery, Oregon Health and Science University, Portland, OR, USA
    J Trauma 71:20-4; discussion 24-5. 2011
    ..We aimed to determine the effect of using alternate LP reconstitution acids on physiologic parameters, blood loss, coagulation, oxidative DNA damage, and proinflammatory cytokines in a polytrauma and hemorrhagic shock model...
  47. doi request reprint The International Normalized Ratio overestimates coagulopathy in stable trauma and surgical patients
    Sean P McCully
    From the Trauma Research Institute of Oregon TRIO S P M, L J F, N R K, T L G, K M W, J A D, M A S, Department of Hematology and Medical Oncology T G D, Oregon Health and Science University, Portland, Oregon
    J Trauma Acute Care Surg 75:947-53. 2013
    ..This study hypothesized that INR does not reflect coagulopathy and should not be used to guide FFP therapy in stable trauma and surgical patients...
  48. ncbi request reprint The international normalized ratio overestimates coagulopathy in patients after major hepatectomy
    Scott G Louis
    Oregon Health and Science University, 3181 S W Sam Jackson Park Rd, Portland, OR 97239, USA Electronic address
    Am J Surg 207:723-7; discussion 727. 2014
    ..The International Normalized Ratio (INR) is commonly used to guide therapy after hepatectomy. We hypothesized that the use of thrombelastography (TEG) would demonstrate a decreased incidence of hypocoagulability in this patient population...
  49. doi request reprint Hyperosmolar reconstituted lyophilized plasma is an effective low-volume hemostatic resuscitation fluid for trauma
    Tim H Lee
    From the Division of Trauma, Critical Care and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon
    J Trauma Acute Care Surg 75:369-75. 2013
    ..We performed this study to optimize reconstituted lyophilized plasma (LP) into a minimal volume fluid that provides effective hemostatic resuscitation for trauma while minimizing logistical limitations...
  50. ncbi request reprint The effect of recombinant factor VIIa on noncoagulopathic pigs with grade V liver injuries
    Martin A Schreiber
    Department of Surgery and Medicine, Baylor College of Medicine, Houston, TX, USA
    J Am Coll Surg 196:691-7. 2003
    ..This study was performed to determine if rFVIIa would reduce blood loss after a Grade V liver injury in noncoagulopathic pigs when used as sole therapy...
  51. ncbi request reprint Management of the open abdomen during the global war on terror
    Gordon M Riha
    Department of Surgery, Division of Trauma, Critical Care, and Acute Care Surgery, Oregon Health and Science University, Portland, OR 97239 3098, USA
    JAMA Surg 148:59-64. 2013
    ..To evaluate factors that are predictive of delayed abdominal closure in patients injured during military conflict...
  52. pmc Coordination and management of multicenter clinical studies in trauma: Experience from the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study
    Mohammad H Rahbar
    Biostatistics, Epidemiology, and Research Design Core, Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA
    Resuscitation 83:459-64. 2012
    ....
  53. ncbi request reprint Hextend attenuates hypercoagulability after severe liver injury in swine
    S Rob Todd
    Department of Surgery, The University of Texas Health Science Center at Houston, Texas 77030, USA
    J Trauma 59:589-93; discussion 593-4. 2005
    ..A resuscitation regimen that modulates this coagulopathy may prove beneficial. We sought to evaluate the effects of lactated Ringer's (LR) solution and Hextend on the resuscitation of uncontrolled hemorrhagic shock...
  54. ncbi request reprint Lyophilized plasma with ascorbic acid decreases inflammation in hemorrhagic shock
    Gregory J Hamilton
    Division of Trauma, Critical Care and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    J Trauma 71:292-7; discussion 297-8. 2011
    ..Previous work demonstrated that LP reconstituted with ascorbic acid (AA) decreased inflammation. Whether the reduction of inflammation was associated with LP or the AA is unknown...
  55. doi request reprint High transfusion ratios are not associated with increased complication rates in patients with severe extremity injuries
    Philbert Y Van
    Division of Trauma, Critical Care, and Acute Care Surgery, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    J Trauma 69:S64-8. 2010
    ..We hypothesized that high ratio transfusion would be associated with no survival benefit and increased complications in combat victims with compressible hemorrhage...
  56. doi request reprint Comparison of abdominal damage control surgery in combat versus civilian trauma
    Chitra N Sambasivan
    Division of Trauma, Critical Care, and Acute Care Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 69:S168-74. 2010
    ..We aimed to compare patients undergoing abdominal damage control surgery across these two very different settings...
  57. ncbi request reprint A predictive model of early mortality in trauma patients
    David A Hampton
    Department of Trauma, Critical Care, and Acute Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA Electronic address
    Am J Surg 207:642-7; discussion 647. 2014
    ..Rapid thrombelastography (rTEG) is a real-time whole-blood viscoelastic coagulation assay. We hypothesized that admission rTEG and clinical data are independent predictors of trauma-related mortality...
  58. pmc Defining when to initiate massive transfusion: a validation study of individual massive transfusion triggers in PROMMTT patients
    Rachael A Callcut
    Division of General Surgery, Department of Surgery, School of Medicine, University of California San Francisco, San Francisco, California 94110, USA
    J Trauma Acute Care Surg 74:59-65, 67-8; discussion 66-7. 2013
    ..Early predictors of massive transfusion (MT) would prevent undertriage of patients likely to require MT. This study validates triggers using the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study...
  59. doi request reprint Management of colonic injuries in the combat theater
    S David Cho
    Oregon Health and Science University, Portland, Oregon 97239, USA
    Dis Colon Rectum 53:728-34. 2010
    ..This study describes the modern management of battle-related colonic injuries and seeks to determine whether management strategy affects early complications...
  60. doi request reprint Trauma induces a hypercoagulable state that is resistant to hypothermia as measured by thrombelastogram
    Jerome A Differding
    Division of Trauma, Critical Care and Acute Care Surgery, Oregon Health and Science University, Portland, OR, USA
    Am J Surg 201:587-91. 2011
    ....
  61. ncbi request reprint Early versus late recombinant factor VIIa in combat trauma patients requiring massive transfusion
    Jeremy G Perkins
    Hematology Oncology Service Department of Medicine, Walter Reed Army Medical Center, Washington, DC 20307, and the Trauma Critical Care Section, Oregon Health and Science University, Portland, USA
    J Trauma 62:1095-9; discussion 1099-101. 2007
    ..We hypothesized that recombinant factor VIIa (rFVIIa) administered to massive transfusion patients before transfusion of 8 units of blood (early) would reduce transfusion requirements compared with rFVIIa after 8 units (late)...
  62. ncbi request reprint Advanced hemostatic dressings are not superior to gauze for care under fire scenarios
    Jennifer M Watters
    Division of Trauma, Critical Care, and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    J Trauma 70:1413-9. 2011
    ..Advanced hemostatic dressings perform superior to standard gauze (SG) in animal hemorrhage models but require 2 minutes to 5 minutes application time, which is not feasible on the battlefield...
  63. doi request reprint The effects of location and low-molecular-weight heparin administration on deep vein thrombosis outcomes in trauma patients
    Tim H Lee
    Division of Trauma, Critical Care and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    J Trauma Acute Care Surg 74:476-81. 2013
    ..The purposes of this study were to assess the rates of PE in above-knee versus below-knee DVT and longitudinally evaluate outcomes of DVT treated with LMWH therapy...
  64. doi request reprint Incidence of deep vein thrombosis is increased with 30 mg twice daily dosing of enoxaparin compared with 40 mg daily
    Gordon M Riha
    Division of Trauma, Critical Care, and Acute Care Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Mail Code L 611, Portland, OR 97239 3098, USA
    Am J Surg 203:598-602. 2012
    ....
  65. pmc Resuscitation of haemorrhagic shock with normal saline vs. lactated Ringer's: effects on oxygenation, extravascular lung water and haemodynamics
    Charles R Phillips
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Oregon Health and Science University, Physicians Pavilion, Suite 340, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Crit Care 13:R30. 2009
    ..These experiments were designed to determine if differences exist because of crystalloid fluid type in the development of oedema, the impact on oxygenation and the haemodynamic response to fluid administration in early HSR...
  66. pmc Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial
    Eileen M Bulger
    Department of Surgery, University of Washington, Seattle, USA
    JAMA 304:1455-64. 2010
    ..Hypertonic fluids restore cerebral perfusion with reduced cerebral edema and modulate inflammatory response to reduce subsequent neuronal injury and thus have potential benefit in resuscitation of patients with traumatic brain injury (TBI)...
  67. doi request reprint Severe traumatic injury: regional variation in incidence and outcome
    Joseph P Minei
    Division of Burn, Trauma and Critical Care, Department of Surgery, UT Southwestern Medical Center, Dallas, TX 75390 9158, USA
    Ann Surg 252:149-57. 2010
    ..The objective of this study was to determine whether the incidence and outcome associated with severe traumatic injury differs across geographic regions of North America...
  68. ncbi request reprint Resuscitation with normal saline (NS) vs. lactated ringers (LR) modulates hypercoagulability and leads to increased blood loss in an uncontrolled hemorrhagic shock swine model
    Laszlo N Kiraly
    Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 61:57-64; discussion 64-5. 2006
    ..The purpose of this study was to compare the effects of LR and NS on coagulation in an uncontrolled hemorrhagic swine model. We hypothesized resuscitation with LR would produce hypercoagulability...
  69. doi request reprint High ratios of plasma and platelets to packed red blood cells do not affect mortality in nonmassively transfused patients
    Chitra N Sambasivan
    Division of Trauma, Critical Care and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 71:S329-36. 2011
    ..We aimed to determine the effect of high ratios of fresh frozen plasma (FFP) and platelets (PLT) to packed red blood cells (PRBC) in nonmassively transfused patients...
  70. doi request reprint Effect of high product ratio massive transfusion on mortality in blunt and penetrating trauma patients
    Susan E Rowell
    Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 71:S353-7. 2011
    ..This study was performed to determine whether mortality after high product ratio massive transfusion is different in blunt and penetrating trauma patients...
  71. doi request reprint A highly porous silica and chitosan-based hemostatic dressing is superior in controlling hemorrhage in a severe groin injury model in swine
    Chitra N Sambasivan
    Department of Surgery, Trauma Critical Care Section, Oregon Health and Science University, Portland, OR 97239, USA
    Am J Surg 197:576-80; discussion 580. 2009
    ..This study compared the efficacy of 3 hemostatic dressings in a severe groin injury model in swine...
  72. ncbi request reprint Lactated Ringer's is superior to normal saline in the resuscitation of uncontrolled hemorrhagic shock
    S Rob Todd
    Methodist Hospital, Houston, TX 77030, USA
    J Trauma 62:636-9. 2007
    ..We hypothesized that, aside from hyperchloremic acidosis, NS resuscitation would be similar to that of LR in a swine model of uncontrolled hemorrhage...
  73. ncbi request reprint Coagulopathy: its pathophysiology and treatment in the injured patient
    Brandon H Tieu
    Department of Surgery, Division of Trauma and Critical Care, Oregon Health and Science University, Portland, Oregon 97239, USA
    World J Surg 31:1055-64. 2007
    ..Its use has been proven to be safe and beneficial in this setting and warrants further investigation as an adjunct to the management of civilian trauma patients...
  74. pmc A critical assessment of the out-of-hospital trauma triage guidelines for physiologic abnormality
    Craig D Newgard
    Department of Emergency Medicine, Center for Policy and Research in Emergency Medicine, Oregon Health and Science University, Portland, Oregon, USA
    J Trauma 68:452-62. 2010
    ..We assessed whether more restrictive physiologic criteria would improve the specificity of this triage step without missing high-risk patients...
  75. doi request reprint Transfusion of aged packed red blood cells results in decreased tissue oxygenation in critically injured trauma patients
    Laszlo N Kiraly
    Division of Trauma and Critical Care, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 67:29-32. 2009
    ..The transfusion of older blood has been shown to be detrimental in retrospective studies. This study aims to study the effect of the age of the blood transfused on the tissue oxygenation using near infrared spectroscopy...
  76. doi request reprint Update and new developments in the management of the exsanguinating patient
    Gordon M Riha
    Department of Surgery, Division of Trauma, Critical Care, and Acute Care Surgery, Oregon Health and Science University, Portland, OR 97239, USA
    J Intensive Care Med 28:46-57. 2013
    ..Finally, adjuncts including the most recent advances in hemorrhage control, identification of early predictors for massive transfusion, and utilization of pharmacologic and complementary factor agent therapy will be discussed...
  77. doi request reprint Correlation of conventional thrombelastography and rapid thrombelastography in trauma
    Tim H Lee
    Department of Surgery, Division of Trauma, Critical Care and Acute Care Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Mail Code L 611, Portland, OR 97239 3098, USA
    Am J Surg 205:521-7; discussion 527. 2013
    ..The purpose of this study was to determine the correlation of rapid thrombelastographic values with conventional thrombelastographic values in trauma patients...
  78. doi request reprint Blood volume analysis can distinguish true anemia from hemodilution in critically ill patients
    Philbert Y Van
    Division of Trauma, Critical Care, and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon, USA
    J Trauma 70:646-51. 2011
    ..In critically ill patients who are fluid resuscitated, pHct may not adequately represent red blood cell volume (RBCV). We hypothesize that the use of pHct alone may overestimate anemia, potentially leading to unnecessary interventions...
  79. doi request reprint Thrombelastography versus AntiFactor Xa levels in the assessment of prophylactic-dose enoxaparin in critically ill patients
    Philbert Y Van
    Division of Trauma and Critical Care, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    J Trauma 66:1509-15; discussion 1515-7. 2009
    ..Thrombelastography (TEG) is used to evaluate coagulation in diverse settings. The purpose of this study was to analyze whether TEG could be used to predict which enoxaparin-treated patients would develop DVT...
  80. pmc Emergency medical services intervals and survival in trauma: assessment of the "golden hour" in a North American prospective cohort
    Craig D Newgard
    Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA
    Ann Emerg Med 55:235-246.e4. 2010
    ..We evaluate the association between emergency medical services (EMS) intervals and mortality among trauma patients with field-based physiologic abnormality...
  81. doi request reprint A high ratio of plasma and platelets to packed red blood cells in the first 6 hours of massive transfusion improves outcomes in a large multicenter study
    Karen A Zink
    Department of Surgery, Trauma Critical Care Section, Oregon Health and Science University, Portland, OR 97239, USA
    Am J Surg 197:565-70; discussion 570. 2009
    ..In trauma, most hemorrhagic deaths occur within the first 6 hours. This study examined the effect on survival of high ratios of fresh frozen plasma (FFP) and platelets (PLTs) to packed red blood cells (PRBCs) in the first 6 hours...
  82. ncbi request reprint Amplification of the proinflammatory transcription factor cascade increases with severity of uncontrolled hemorrhage in swine
    Susan I Brundage
    Department of Surgery, Stanford University Medical Center, Palo Alto, California 94305, USA
    J Surg Res 113:74-80. 2003
    ..to assess whether or not levels of IL-6 mRNA and activity of NF-kappaB and Stat3 correlate with shock severity...
  83. doi request reprint Thrombelastography-identified coagulopathy is associated with increased morbidity and mortality after traumatic brain injury
    Nicholas R Kunio
    Department of Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Mail Code L 223, Portland, OR 97239 3098, USA
    Am J Surg 203:584-8. 2012
    ..The purpose of this study was to determine the relationship between coagulopathy and outcome after traumatic brain injury...
  84. ncbi request reprint Resuscitation with lactated ringer's does not increase inflammatory response in a Swine model of uncontrolled hemorrhagic shock
    Jennifer M Watters
    Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    Shock 22:283-7. 2004
    ..01) and shams (P < 0.05) but were not different from one another (P= 0.83). LR and NS resuscitation have equivalent effects on indices of inflammation in the lungs in our model of uncontrolled hemorrhagic shock...
  85. doi request reprint Defining the limits of resuscitative emergency department thoracotomy: a contemporary Western Trauma Association perspective
    Ernest E Moore
    Department of Surgery, Denver Health, Denver, Colorado 80204, USA
    J Trauma 70:334-9. 2011
    ..The purpose of this prospective multicenter study was to identify injury patterns and physiologic profiles at ED arrival that are compatible with survival...
  86. doi request reprint The use of the Wittmann Patch facilitates a high rate of fascial closure in severely injured trauma patients and critically ill emergency surgery patients
    Brandon H Tieu
    Oregon Health and Science University, Portland, Oregon, USA
    J Trauma 65:865-70. 2008
    ..The purpose of this study was to determine the fascial closure rate using the Wittmann patch. We hypothesized that use of the patch would result in a high closure rate...
  87. ncbi request reprint Measurement of acid-base resuscitation endpoints: lactate, base deficit, bicarbonate or what?
    Michael S Englehart
    Department of Surgery, Oregon Health and Science University, Portland, Oregon 91239, USA
    Curr Opin Crit Care 12:569-74. 2006
    ..This review focuses on the metabolic, hemodynamic and regional perfusion endpoints utilized in the diagnosis of metabolic acidosis resulting from shock. Resuscitation strategies aimed at supranormal oxygen delivery will be discussed...
  88. doi request reprint Military applications of novel hemostatic devices
    Stephanie D Gordy
    Department of Surgery, Oregon Health and Science University, OR, USA
    Expert Rev Med Devices 8:41-7. 2011
    ..This article reviews novel hemostatic agents used by first responders in the military and civilian sectors...
  89. doi request reprint The mRDH bandage provides effective hemostasis in trauma and surgical hemorrhage
    David R King
    Division of Trauma, Critical Care, and Acute Care Surgery, Oregon Health and Science University, Portland, Oregon, USA
    J Trauma 71:S167-70. 2011
    ..Excessive blood loss is an infrequent but important complication of both elective and emergency surgery, increasing the risk of morbidity and mortality and prolonging the duration of hospital stay...
  90. doi request reprint Emerging therapies in traumatic hemorrhage control
    Chitra N Sambasivan
    Department of Surgery, Oregon Health and Science University, Portland, Oregon, USA
    Curr Opin Crit Care 15:560-8. 2009
    ..Hemorrhage remains the primary cause of preventable death after trauma. Rapid and effective early care can improve survival and outcomes. Emerging therapies to address traumatic hemorrhage will be discussed...
  91. doi request reprint Management and outcome of pneumatosis intestinalis
    Melanie S Morris
    Department of Surgery, Oregon Health and Science University, Portland, OR, USA
    Am J Surg 195:679-82; discussion 682-3. 2008
    ..Pneumatosis intestinalis (PI), infiltration of gas into the bowel wall, has traditionally been associated with immediate operative intervention and a high mortality rate...
  92. doi request reprint Achieving hemostasis with topical hemostats: making clinically and economically appropriate decisions in the surgical and trauma settings
    Martin A Schreiber
    Division of Trauma, Critical Care, and Acute Care Surgery, Oregon Health and Science University, Portland, USA
    AORN J 94:S1-20. 2011
    ..Understanding how and when to use each of the available hemostatic agents can greatly affect clinical outcomes and help to limit the overall cost of treatment...
  93. doi request reprint Challenges to effective research in acute trauma resuscitation: consent and endpoints
    John B Holcomb
    Center for Translational Injury Research, University of Texas Health Science Center at Houston, 6410 Fannin St, Houston, TX, USA
    Shock 35:107-13. 2011
    ..The consensus was that more discussion was needed and that consideration of new endpoints for clinical trials in emergency trauma research was a worthwhile and necessary goal...
  94. pmc The availability and use of out-of-hospital physiologic information to identify high-risk injured children in a multisite, population-based cohort
    Craig D Newgard
    Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    Prehosp Emerg Care 13:420-31. 2009
    ....
  95. ncbi request reprint Lidocaine patches reduce pain in trauma patients with rib fractures
    Karen A Zink
    Division of Trauma, Critical Care, and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    Am Surg 77:438-42. 2011
    ..16) and no adverse events. Lidocaine patches are a safe, effective adjunct for rib fracture pain. Lidocaine patches resulted in a sustained reduction in pain, outlasting the duration of therapy...
  96. ncbi request reprint Diagnosis and management of blunt pancreatic ductal injury in the era of high-resolution computed axial tomography
    Swee H Teh
    Department of Surgery, Oregon Health and Science University, 3181 S W Sam Jackson Park Rd, Portland, OR 97239, USA
    Am J Surg 193:641-3; discussion 643. 2007
    ..Computed axial tomography (CAT) scan has historically been unreliable for the detection of ductal injury, but the advent of high-resolution CAT should improve diagnostic accuracy...
  97. ncbi request reprint Correlation of central venous and arterial blood gas measurements in mechanically ventilated trauma patients
    Darren J Malinoski
    Department of Surgery, Oregon Health and Science University, Portland, USA
    Arch Surg 140:1122-5. 2005
    ....
  98. ncbi request reprint Base deficit does not predict mortality when secondary to hyperchloremic acidosis
    Scott A Brill
    William Beaumont Army Medical Center, El Paso, Texas 79920, USA
    Shock 17:459-62. 2002
    ..Failure to properly diagnose this subset of acidotic patients may result in inappropriate clinical interventions due to the erroneous presumption of ongoing tissue hypoxia...
  99. ncbi request reprint Advanced trauma life support, 8th edition, the evidence for change
    John B Kortbeek
    Foothills Medical Centre, Calgary, Alberta T2N 2T9, Canada
    J Trauma 64:1638-50. 2008
    ..New materials related to principles of disaster management have been added. ATLS is a common language teaching one safe way of initial trauma assessment and management...
  100. doi request reprint Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients
    John B Holcomb
    United States Army Institute of Surgical Research, Ft Sam Houston, TX 78234, USA
    Ann Surg 248:447-58. 2008
    ....
  101. ncbi request reprint Immediate effects of dry needling and acupuncture at distant points in chronic neck pain: results of a randomized, double-blind, sham-controlled crossover trial
    Dominik Irnich
    Department of Anesthesiology, University of Munich, Nussbaumstrasse 20, D 80336 Munich, Germany
    Pain 99:83-9. 2002
    ..Acupuncture at distant points improves ROM more than DN; DN was ineffective for motion-related pain...