M A Sanchez


Affiliation: Oregon Health and Science University
Country: USA


  1. request reprint
    Sanchez M, Ullman B, Landfear S, Carter N. Cloning and functional expression of a gene encoding a P1 type nucleoside transporter from Trypanosoma brucei. J Biol Chem. 1999;274:30244-9 pubmed
    ..Genomic Southern blots suggest that there are multiple genes related in sequence to TbNT2, implying the existence of a family of nucleoside transporter genes in these parasites. ..
  2. request reprint
    Sanchez M, Tryon R, Pierce S, Vasudevan G, Landfear S. Functional expression and characterization of a purine nucleobase transporter gene from Leishmania major. Mol Membr Biol. 2004;21:11-8 pubmed
    ..5, 8.5 +/- 0.6, 8.5 +/- 1.1, and 8.8 +/- 4.0 microM, respectively. LmaNT3 is, thus, the first member of the ENT family identified in any organism that functions as a nucleobase rather than nucleoside or nucleoside/nucleobase transporter. ..
  3. request reprint
    Sanchez M, Drutman S, van Ampting M, Matthews K, Landfear S. A novel purine nucleoside transporter whose expression is up-regulated in the short stumpy form of the Trypanosoma brucei life cycle. Mol Biochem Parasitol. 2004;136:265-72 pubmed
  4. Sanchez M, Tryon R, Green J, Boor I, Landfear S. Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions. J Biol Chem. 2002;277:21499-504 pubmed publisher
    ..These results demonstrate that T. brucei expresses multiple purine transporters with distinct substrate specificities and different patterns of expression during the parasite life cycle...