Andrey Ryabinin

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. pmc Urocortins: CRF's siblings and their potential role in anxiety, depression and alcohol drinking behavior
    Andrey E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health and Science University, L470, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Alcohol 46:349-57. 2012
  2. pmc Urocortin 1 microinjection into the mouse lateral septum regulates the acquisition and expression of alcohol consumption
    A E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health and Sciences University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA
    Neuroscience 151:780-90. 2008
  3. ncbi request reprint The urocortin 1 neurocircuit: ethanol-sensitivity and potential involvement in alcohol consumption
    Andrey E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health and Science University, L470, 3181 SW Sam Jackson Park Road, Portland, 97239, USA
    Brain Res Rev 52:368-80. 2006
  4. ncbi request reprint Selective effects of alcohol drinking on restraint-induced expression of immediate early genes in mouse brain
    A E Ryabinin
    Portland Alcohol Research Center, Department of Behavioral Neuroscience, Oregon Health Sciences University, 97201, USA
    Alcohol Clin Exp Res 23:1272-80. 1999
  5. ncbi request reprint Urocortin 1-containing neurons in the human Edinger-Westphal nucleus
    A E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, 97239, USA
    Neuroscience 134:1317-23. 2005
  6. ncbi request reprint High alcohol/sucrose consumption during dark circadian phase in C57BL/6J mice: involvement of hippocampus, lateral septum and urocortin-positive cells of the Edinger-Westphal nucleus
    Andrey E Ryabinin
    Department of Behavioral Neuroscience, L470, Portland Alcohol Research Center, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
    Psychopharmacology (Berl) 165:296-305. 2003
  7. ncbi request reprint The corticotropin-releasing factor/urocortin system and alcohol
    Andrey E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health and Sciences University, Portland 97201 3098, USA
    Alcohol Clin Exp Res 26:714-22. 2002
  8. ncbi request reprint Cocaine- and alcohol-mediated expression of inducible transcription factors is blocked by pentobarbital anesthesia
    A E Ryabinin
    Department of Behavioral Neuroscience, L470, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
    Brain Res 877:251-61. 2000
  9. ncbi request reprint ITF expression in mouse brain during acquisition of alcohol self-administration
    A E Ryabinin
    Department of Behavioral Neuroscience, L470, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
    Brain Res 890:192-5. 2001
  10. ncbi request reprint ITF mapping after drugs of abuse: pharmacological versus perceptional effects
    A E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health Sciences University L470, 3181 SW Sam Jackson Park Road, Portland, Oregon 97201, USA
    Acta Neurobiol Exp (Wars) 60:547-55. 2000

Research Grants

  1. Perioculomotor area and alcohol
    Andrey Ryabinin; Fiscal Year: 2009
  2. Excessive drinking and urocortin 1 neurocircuit
    Andrey Ryabinin; Fiscal Year: 2007
  3. Alcohol drinking in affiliative rodents
    Andrey Ryabinin; Fiscal Year: 2007
  4. Urocortin, Edinger-Westphal nucleus & EtOH consumption
    Andrey Ryabinin; Fiscal Year: 2007
  5. NEUROANATOMICAL SUBSTRATES OF ALCOHOL-INDUCED AMNESIA
    Andrey Ryabinin; Fiscal Year: 2001
  6. Perioculomotor area and alcohol
    Andrey E Ryabinin; Fiscal Year: 2010

Detail Information

Publications35

  1. pmc Urocortins: CRF's siblings and their potential role in anxiety, depression and alcohol drinking behavior
    Andrey E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health and Science University, L470, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Alcohol 46:349-57. 2012
    ..Because of complex distribution of Ucns in the nervous system, advances in this field will critically depend on development of new tools allowing site-specific analyses of the roles of Ucns and CRF...
  2. pmc Urocortin 1 microinjection into the mouse lateral septum regulates the acquisition and expression of alcohol consumption
    A E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health and Sciences University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA
    Neuroscience 151:780-90. 2008
    ..Taken together, these studies confirm the importance of lateral septum innervation by Ucn1 in the regulation of alcohol consumption...
  3. ncbi request reprint The urocortin 1 neurocircuit: ethanol-sensitivity and potential involvement in alcohol consumption
    Andrey E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health and Science University, L470, 3181 SW Sam Jackson Park Road, Portland, 97239, USA
    Brain Res Rev 52:368-80. 2006
    ..This paper reviews the current knowledge of the Ucn1 neurocircuit and the evidence for its involvement in alcohol-related behaviors, and proposes a mechanism for its involvement in the regulation of alcohol consumption...
  4. ncbi request reprint Selective effects of alcohol drinking on restraint-induced expression of immediate early genes in mouse brain
    A E Ryabinin
    Portland Alcohol Research Center, Department of Behavioral Neuroscience, Oregon Health Sciences University, 97201, USA
    Alcohol Clin Exp Res 23:1272-80. 1999
    ..In this study, immunohistochemical expression analysis of immediate early genes c-fos, fosB, and zif268 was performed in brain of C57BL/6J mice after voluntary alcohol consumption...
  5. ncbi request reprint Urocortin 1-containing neurons in the human Edinger-Westphal nucleus
    A E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, 97239, USA
    Neuroscience 134:1317-23. 2005
    ....
  6. ncbi request reprint High alcohol/sucrose consumption during dark circadian phase in C57BL/6J mice: involvement of hippocampus, lateral septum and urocortin-positive cells of the Edinger-Westphal nucleus
    Andrey E Ryabinin
    Department of Behavioral Neuroscience, L470, Portland Alcohol Research Center, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
    Psychopharmacology (Berl) 165:296-305. 2003
    ..Previous studies mapping changes in brain activity used rodent models of alcohol drinking with relatively low alcohol intakes...
  7. ncbi request reprint The corticotropin-releasing factor/urocortin system and alcohol
    Andrey E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health and Sciences University, Portland 97201 3098, USA
    Alcohol Clin Exp Res 26:714-22. 2002
    ..Mehmert, R. Camarini, Joseph A. Kim, Heather N. Koenig, Michelle A. Nannini, and Clyde W. Hodge; and (5) Selective sensitivity of urocortin-containing neurons to alcohol self-administration, by Andrey E. Ryabinin and Ryan K. Bachtell...
  8. ncbi request reprint Cocaine- and alcohol-mediated expression of inducible transcription factors is blocked by pentobarbital anesthesia
    A E Ryabinin
    Department of Behavioral Neuroscience, L470, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
    Brain Res 877:251-61. 2000
    ..Our data suggest that in the absence of conscious awareness of drug-associated cues, cocaine and alcohol activate only a fraction of the neural elements engaged in the unanesthetized state...
  9. ncbi request reprint ITF expression in mouse brain during acquisition of alcohol self-administration
    A E Ryabinin
    Department of Behavioral Neuroscience, L470, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
    Brain Res 890:192-5. 2001
    ..Stronger expression of c-Fos in EW was found in animals repeatedly consuming ethanol-containing solutions. These findings underscore the potential importance of EW in alcohol-related behaviors...
  10. ncbi request reprint ITF mapping after drugs of abuse: pharmacological versus perceptional effects
    A E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health Sciences University L470, 3181 SW Sam Jackson Park Road, Portland, Oregon 97201, USA
    Acta Neurobiol Exp (Wars) 60:547-55. 2000
    ..Given the low resolution of invasive techniques, ITF mapping experiments will continually contribute to our understanding of mechanisms of drug addiction and alcoholism...
  11. ncbi request reprint Alcohol drinking produces brain region-selective changes in expression of inducible transcription factors
    R K Bachtell
    Department of Behavioral Neuroscience, L470, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
    Brain Res 847:157-65. 1999
    ..Second, they suggest a relationship between ITF expression in AcbC, CeMPV and EW and the level of alcohol intoxication...
  12. ncbi request reprint Effects of acute alcohol administration on object recognition learning in C57BL/6J mice
    Andrey E Ryabinin
    Department of Behavioral Neuroscience, L470, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
    Pharmacol Biochem Behav 71:307-12. 2002
    ..Our results show that in C57BL/6J mice, ethanol intoxication interferes with exploratory activity during object exploration, but not with consolidation of memory...
  13. ncbi request reprint The Edinger-Westphal-lateral septum urocortin pathway and its relationship to alcohol consumption
    Ryan K Bachtell
    Department of Behavioral Neuroscience, Oregon Health and Science University and Portland Alcohol Research Center, Portland, Oregon 97239, USA
    J Neurosci 23:2477-87. 2003
    ..Taken together, these studies provide substantial evidence for involvement of the EW-LS Ucn pathway in alcohol consumption...
  14. ncbi request reprint Lesions of the Edinger-Westphal nucleus in C57BL/6J mice disrupt ethanol-induced hypothermia and ethanol consumption
    Ryan K Bachtell
    Department of Behavioural Neuroscience, Oregon Health and Science University and Portland Alcohol Research Center, Portland, OR 97239, USA
    Eur J Neurosci 20:1613-23. 2004
    ..Taken together, the findings suggest that the EW may function as a sensor for ethanol, which can influence ethanol consumption and preference...
  15. pmc FOS expression induced by an ethanol-paired conditioned stimulus
    Katherine G Hill
    Department of Behavioral Neuroscience and Portland Alcohol Research Center, Oregon Health and Science University, Portland, OR 97239 3098, United States
    Pharmacol Biochem Behav 87:208-21. 2007
    ..Overall, these data suggest an important role for the mesolimbic dopamine pathway, extended amygdala and hippocampus in ethanol-induced conditioning...
  16. ncbi request reprint Brain region-specific regulation of urocortin 1 innervation and corticotropin-releasing factor receptor type 2 binding by ethanol exposure
    Adam Z Weitemier
    Department of Behavioral Neuroscience, Oregon Health and Science University and Portland Alcohol Research Center, Portland, Oregon 97239, USA
    Alcohol Clin Exp Res 29:1610-20. 2005
    ..We investigated whether repeated ethanol exposure affects Ucn1 and Ucn1-responsive corticotropin-releasing factor type-2 receptors (CRF2)...
  17. ncbi request reprint Expression of c-Fos in the mouse Edinger-Westphal nucleus following ethanol administration is not secondary to hypothermia or stress
    Victoria F Turek
    Department of Behavioral Neuroscience, Oregon Health and Sciences University, Portland, OR 97239, USA
    Brain Res 1063:132-9. 2005
    ..These data demonstrate that activation of EW after EtOH is unrelated to hypothermia or stress...
  18. ncbi request reprint Patterns of brain activation associated with contextual conditioning to methamphetamine in mice
    Justin S Rhodes
    Portland Alcohol Research Center, Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, USA
    Behav Neurosci 119:759-71. 2005
    ..A batch effect among immunohistochemical assays was demonstrated. Results implicate specific brain regions in classical conditioning to meth and demonstrate the importance of considering locomotor activity and batch in a c-Fos study...
  19. ncbi request reprint Subregion-specific differences in hippocampal activity between Delay and Trace fear conditioning: an immunohistochemical analysis
    Adam Z Weitemier
    Department of Behavioral Neuroscience, L470, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Brain Res 995:55-65. 2004
    ..The present study confirms differential activation of hippocampal subregions in Delay and Trace fear conditioning...
  20. ncbi request reprint Alcohol-induced memory impairment in trace fear conditioning: a hippocampus-specific effect
    Adam Z Weitemier
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97201, USA
    Hippocampus 13:305-15. 2003
    ....
  21. pmc Biological contribution to social influences on alcohol drinking: evidence from animal models
    Allison M J Anacker
    Department of Behavioral Neuroscience, Oregon Health and Science University, 3181 SW Sam Jackson Pk Rd L470, Portland, OR 97239, USA
    Int J Environ Res Public Health 7:473-93. 2010
    ..These findings strongly suggest that mechanisms by which social factors influence drinking have biological roots, and can be studied using rapidly developing new animal models...
  22. ncbi request reprint Ataxia and c-Fos expression in mice drinking ethanol in a limited access session
    Amanda L Sharpe
    Portland Alcohol Research Center, Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97239, USA
    Alcohol Clin Exp Res 29:1419-26. 2005
    ..Thus, the goal of this study was to demonstrate ataxia and to examine changes in c-Fos expression in mice after self-administration of intoxicating doses of ethanol...
  23. pmc Corticotropin-releasing factor-1 receptor involvement in behavioral neuroadaptation to ethanol: a urocortin1-independent mechanism
    Raul Pastor
    Departments of Behavioral Neuroscience, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Proc Natl Acad Sci U S A 105:9070-5. 2008
    ..A CRF/CRF1-mediated mechanism involving the HPA axis is proposed for acquisition, whereas an extrahypothalamic CRF/CRF1 participation is suggested for expression of sensitization to EtOH...
  24. ncbi request reprint Alcohol-induced c-Fos expression in the Edinger-Westphal nucleus: pharmacological and signal transduction mechanisms
    Ryan K Bachtell
    Department of Behavioral Neuroscience, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
    J Pharmacol Exp Ther 302:516-24. 2002
    ....
  25. ncbi request reprint Identification of temperature-sensitive neural circuits in mice using c-Fos expression mapping
    Ryan K Bachtell
    Department of Behavioral Neuroscience, L470, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Brain Res 960:157-64. 2003
    ....
  26. ncbi request reprint Lesions of the Edinger-Westphal nucleus alter food and water consumption
    Adam Z Weitemier
    Department of Behavioral Neuroscience, Oregon Health and Science University, USA
    Behav Neurosci 119:1235-43. 2005
    ..EW lesion had no effect on indices of basal metabolic activity, including plasma glucose level and body temperature. These effects suggest that the peptidergic neurons of the EW regulate food consumption...
  27. pmc Postnatal developmental profile of urocortin 1 and cocaine- and amphetamine-regulated transcript in the perioculomotor region of C57BL/6J mice
    Anita Cservenka
    Department of Behavioral Neuroscience, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Brain Res 1319:33-43. 2010
    ..The lack of brain Ucn 1 immunoreactivity at birth and the gradual postnatal increase in Ucn 1 in pIIIu suggests that this peptide plays a greater behavioral role in adulthood than during the early postnatal development of an organism...
  28. ncbi request reprint Differences in the urocortin 1 system between long-sleep and short-sleep mice
    Victoria F Turek
    Department of Behavioral Neuroscience, Portland Alcohol Research Center, Oregon Health and Science University, Portland, OR 92121, USA
    Genes Brain Behav 7:113-9. 2008
    ..In addition, these results lend further support to previous findings implicating Ucn1-containing projections from npEW to the dorsal raphe in ethanol-induced hypothermia...
  29. pmc Post-retrieval disruption of a cocaine conditioned place preference by systemic and intrabasolateral amygdala beta2- and alpha1-adrenergic antagonists
    Rick E Bernardi
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97239, USA
    Learn Mem 16:777-89. 2009
    ..These systemic and site-specific injections, as well as the FOS immunohistochemical analyses, implicate the importance of specific noradrenergic signaling mechanisms within the BLA in post-retrieval plasticity...
  30. pmc Increased perioculomotor urocortin 1 immunoreactivity in genetically selected alcohol preferring rats
    Irina Fonareva
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon, USA
    Alcohol Clin Exp Res 33:1956-65. 2009
    ..Furthermore, the effects of gender on the relationship between Ucn 1 and tyrosine hydroxylase (TH) in pIII and alcohol preference in rats have not been previously assessed...
  31. pmc Comparison of the distributions of urocortin-containing and cholinergic neurons in the perioculomotor midbrain of the cat and macaque
    Paul J May
    Department of Anatomy, University of Mississippi Medical Center, Jackson, Mississippi 39202, USA
    J Comp Neurol 507:1300-16. 2008
    ..This will allow more effective scientific discourse on the connections and function of groups such as the periculomotor urocortin (pIII(U)) and preganglionic (pIII(PG)) populations...
  32. pmc CRF receptors in the nucleus accumbens modulate partner preference in prairie voles
    Miranda M Lim
    Center for Behavioral Neuroscience and Department of Psychiatry and Behavioral Sciences, 954 Gatewood Road NE, Emory University, Atlanta, GA 30322, USA
    Horm Behav 51:508-15. 2007
    ..This supports the hypothesis that local CRF release into NAcc could activate CRF(1) or CRF(2) receptors in the region. Taken together, our results reveal a novel role for accumbal CRF systems in social behavior...
  33. ncbi request reprint New neuronal networks involved in ethanol reinforcement
    Kalervo Kiianmaa
    Department of Mental Helath and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Alcohol Clin Exp Res 27:209-19. 2003
    ..Finn, and (6) Potential contribution of the urocortin system to regulation of alcohol self-administration, by Andrey E. Ryabinin and Ryan K. Bachtell.(B)..
  34. pmc Distribution of corticotropin-releasing factor and urocortin 1 in the vole brain
    Miranda M Lim
    Center for Behavioral Neuroscience, Emory University School of Medicine, Atlanta, GA, USA
    Brain Behav Evol 68:229-40. 2006
    ..Our findings generate novel hypotheses regarding the evolutionary mechanisms underlying the neural circuitry of species-typical social behaviors...
  35. pmc Transcriptional signatures of cellular plasticity in mice lacking the alpha1 subunit of GABAA receptors
    Igor Ponomarev
    Waggoner Center for Alcohol and Addiction Research, University of Texas, Austin, Texas 78712, USA
    J Neurosci 26:5673-83. 2006
    ....

Research Grants13

  1. Perioculomotor area and alcohol
    Andrey Ryabinin; Fiscal Year: 2009
    ..These studies will provide novel important information indicating how these recently identified neurons robustly regulate alcohol intake. ..
  2. Excessive drinking and urocortin 1 neurocircuit
    Andrey Ryabinin; Fiscal Year: 2007
    ....
  3. Alcohol drinking in affiliative rodents
    Andrey Ryabinin; Fiscal Year: 2007
    ....
  4. Urocortin, Edinger-Westphal nucleus & EtOH consumption
    Andrey Ryabinin; Fiscal Year: 2007
    ..The long-term goal of these studies is to understand the mechanisms regulating alcohol consumption. Such knowledge is important for development of pharmacotherapy of alcoholism ..
  5. NEUROANATOMICAL SUBSTRATES OF ALCOHOL-INDUCED AMNESIA
    Andrey Ryabinin; Fiscal Year: 2001
    ..Taken together, these studies will provide valuable insight at several levels of analysis of alcohol~s action on cognitive functions and eventually allow to start understanding of the mechanisms involved in alcohol-induced amnesia. ..
  6. Perioculomotor area and alcohol
    Andrey E Ryabinin; Fiscal Year: 2010
    ..These studies will provide novel important information indicating how these recently identified neurons robustly regulate alcohol intake. ..