Detail Information
Publications
Measuring copper and zinc superoxide dismutase from spinal cord tissue using electrospray mass spectrometryTimothy W Rhoads
Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA
Anal Biochem 415:52-8. 2011..SOD1 could be measured in subpicomole amounts and resolved to within 2 Da of the predicted parent mass. The methods can be adapted to quantify modifications to other proteins in vivo that can be resolved by mass spectrometry...
Using theoretical protein isotopic distributions to parse small-mass-difference post-translational modifications via mass spectrometryTimothy W Rhoads
Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA
J Am Soc Mass Spectrom 24:115-24. 2013..Although techniques like ICP-MS can measure total metal in solution, this is the first method able to assess the metal-binding and sulfhydryl reduction of SOD1 at the individual subunit level and is applicable to many other proteins...
