Mark E Pennesi

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Measuring cone density in a Japanese macaque (Macaca fuscata) model of age-related macular degeneration with commercially available adaptive optics
    Mark E Pennesi
    Department of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Blvd, 97239, Portland, OR, USA
    Adv Exp Med Biol 801:309-16. 2014
  2. pmc Long-term characterization of retinal degeneration in rd1 and rd10 mice using spectral domain optical coherence tomography
    Mark E Pennesi
    Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239, USA
    Invest Ophthalmol Vis Sci 53:4644-56. 2012
  3. pmc Animal models of age related macular degeneration
    Mark E Pennesi
    Department of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239, USA
    Mol Aspects Med 33:487-509. 2012
  4. pmc Residual electroretinograms in young Leber congenital amaurosis patients with mutations of AIPL1
    Mark E Pennesi
    Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    Invest Ophthalmol Vis Sci 52:8166-73. 2011
  5. ncbi request reprint Intravitreal moxifloxacin: retinal safety study with electroretinography and histopathology in animal models
    Hua Gao
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Invest Ophthalmol Vis Sci 47:1606-11. 2006
  6. ncbi request reprint Effects of elevated intraocular pressure on mouse retinal ganglion cells
    Jianzhong Ji
    Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, 6565 Fannin, NC 205, Houston, TX 77030, USA
    Vision Res 45:169-79. 2005
  7. ncbi request reprint A role for bHLH transcription factors in retinal degeneration and dysfunction
    Mark E Pennesi
    Department of Ophthalmology, Baylor College of Medicine, Houston, Texas 77030, USA
    Adv Exp Med Biol 572:155-61. 2006
  8. pmc Genetic dissection of rod and cone pathways in the dark-adapted mouse retina
    Muhammad M Abd-El-Barr
    Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, One Baylor Plaza, NC 205, Houston, TX 77030, USA
    J Neurophysiol 102:1945-55. 2009
  9. ncbi request reprint Visual acuity in patients with Leber's congenital amaurosis and early childhood-onset retinitis pigmentosa
    Saloni Walia
    Department of Ophthalmology, University of Illinois at Chicago, Chicago, Illinois, USA
    Ophthalmology 117:1190-8. 2010
  10. pmc A mouse model of elevated intraocular pressure: retina and optic nerve findings
    Ronald L Gross
    Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, Tex, USA
    Trans Am Ophthalmol Soc 101:163-9; discussion 169-71. 2003

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Measuring cone density in a Japanese macaque (Macaca fuscata) model of age-related macular degeneration with commercially available adaptive optics
    Mark E Pennesi
    Department of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Blvd, 97239, Portland, OR, USA
    Adv Exp Med Biol 801:309-16. 2014
    ..Future studies will quantify the longitudinal change in the cone mosaic and its relationship to the severity of drusen in these animals. ..
  2. pmc Long-term characterization of retinal degeneration in rd1 and rd10 mice using spectral domain optical coherence tomography
    Mark E Pennesi
    Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239, USA
    Invest Ophthalmol Vis Sci 53:4644-56. 2012
    ....
  3. pmc Animal models of age related macular degeneration
    Mark E Pennesi
    Department of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, OR 97239, USA
    Mol Aspects Med 33:487-509. 2012
    ..Models for induced choroidal neovascularization have served as the backbone for testing new therapies. This article will review the diversity of animal models that exist for AMD as well as their strengths and limitations...
  4. pmc Residual electroretinograms in young Leber congenital amaurosis patients with mutations of AIPL1
    Mark E Pennesi
    Casey Eye Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    Invest Ophthalmol Vis Sci 52:8166-73. 2011
    ..To describe in detail the clinical phenotype and electrophysiological features of three patients with Leber congenital amaurosis caused by mutations of AIPL1...
  5. ncbi request reprint Intravitreal moxifloxacin: retinal safety study with electroretinography and histopathology in animal models
    Hua Gao
    Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Invest Ophthalmol Vis Sci 47:1606-11. 2006
    ..To determine whether moxifloxacin can be used safely as an intraocular antibiotic, retinal safety of intravitreal moxifloxacin was studied with electroretinography (ERG) and histopathology in animal models...
  6. ncbi request reprint Effects of elevated intraocular pressure on mouse retinal ganglion cells
    Jianzhong Ji
    Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, 6565 Fannin, NC 205, Houston, TX 77030, USA
    Vision Res 45:169-79. 2005
    ..The RGCs in eyes with elevated IOP were TUNEL-positive, with increased caspase-3 and decreased Bcl-2, consistent with apoptosis as the mechanism of neuronal cell death...
  7. ncbi request reprint A role for bHLH transcription factors in retinal degeneration and dysfunction
    Mark E Pennesi
    Department of Ophthalmology, Baylor College of Medicine, Houston, Texas 77030, USA
    Adv Exp Med Biol 572:155-61. 2006
  8. pmc Genetic dissection of rod and cone pathways in the dark-adapted mouse retina
    Muhammad M Abd-El-Barr
    Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, One Baylor Plaza, NC 205, Houston, TX 77030, USA
    J Neurophysiol 102:1945-55. 2009
    ....
  9. ncbi request reprint Visual acuity in patients with Leber's congenital amaurosis and early childhood-onset retinitis pigmentosa
    Saloni Walia
    Department of Ophthalmology, University of Illinois at Chicago, Chicago, Illinois, USA
    Ophthalmology 117:1190-8. 2010
    ..To correlate visual acuity of patients with Leber's congenital amaurosis (LCA) and early childhood-onset retinitis pigmentosa (RP) with mutations in underlying LCA genes...
  10. pmc A mouse model of elevated intraocular pressure: retina and optic nerve findings
    Ronald L Gross
    Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, Tex, USA
    Trans Am Ophthalmol Soc 101:163-9; discussion 169-71. 2003
    ..To develop and characterize a mouse model of elevated intraocular pressure (IOP) as a means to investigate the underlying cellular and genetic mechanisms of glaucomatous optic neuropathy...
  11. ncbi request reprint Retinal morphology of patients with achromatopsia during early childhood: implications for gene therapy
    Paul Yang
    Casey Eye Institute, Oregon Health and Science University, Portland
    JAMA Ophthalmol 132:823-31. 2014
    ..While older children and adults with achromatopsia have been studied, less is known of young children with achromatopsia...
  12. pmc Observations regarding retinopathy in mitochondrial trifunctional protein deficiencies
    Autumn L Fletcher
    Department of Molecular and Medical Genetics, School of Medicine, Oregon Health and Science University, Mail Code L 103, 3181 SW Sam Jackson Park Rd Portland, OR 97239, USA
    Mol Genet Metab 106:18-24. 2012
    ....
  13. pmc Ophthalmic findings in an infant with phosphomannomutase deficiency
    Wyatt B Messenger
    Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Blvd, Portland, OR, 97239, USA
    Doc Ophthalmol 128:149-53. 2014
    ..We present the ocular features including full-field electroretinography (ff-ERG) and spectral domain optical coherence tomography (SD-OCT) in a 14-month-old infant with congenital disorder of glycosylation type 1a (PMM2-CDG)...
  14. ncbi request reprint Intravitreal voriconazole: an electroretinographic and histopathologic study
    Hua Gao
    Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA
    Arch Ophthalmol 122:1687-92. 2004
    ..Voriconazole, a novel triazole antifungal agent, presents potent activity against a broad spectrum of yeast and molds...
  15. pmc Guanylate cyclase-activating protein (GCAP) 1 rescues cone recovery kinetics in GCAP1/GCAP2 knockout mice
    Mark E Pennesi
    Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 100:6783-8. 2003
    ..These studies reveal that, similar to rods, deletion of GCAP1 and GCAP2 delays the recovery of light responses in cones and GCAP1 restores the recovery of cone responses in the absence of GCAP2...
  16. ncbi request reprint BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration
    Mark E Pennesi
    Department of Ophthalmology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 23:453-61. 2003
    ..Loss of BETA2/NeuroD1 results in an age-related degeneration of both rods and cones...
  17. doi request reprint The 'dark' side of sedation: 12 years of office-based pediatric deep sedation for electroretinography in the dark
    Kirk Lalwani
    Department of Anesthesiology and Perioperative Medicine, Oregon Health and Science University, Doernbecher Children s Hospital, Portland, OR 97239, USA
    Paediatr Anaesth 21:65-71. 2011
    ..Analyze pediatric ERG data for adverse events, interventions, and outcomes of propofol sedations performed in near-complete darkness...
  18. doi request reprint Subretinal delivery of immunoglobulin G with gold nanoparticles in the rabbit eye
    Atsushi Hayashi
    Department of Ophthalmology, University of California, San Francisco, CA, USA
    Jpn J Ophthalmol 53:249-56. 2009
    ..To examine the feasibility of subretinal delivery of immunoglobulin G (IgG) adsorbed onto gold nanoparticles (GNPs) and its histologic distribution in the rabbit retina after the injection...