Research Topics
| Barry S OkenSummaryAffiliation: Oregon Health and Science University Country: USA Publications
Research Grants
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Detail Information
Publications
Stress-related cognitive dysfunction in dementia caregiversBarry S Oken
Departments of Neurology and Behavioral Neuroscience, Oregon Health and Science University, Irina Fonareva, Portland, OR 97239, USA
J Geriatr Psychiatry Neurol 24:191-8. 2011..Of note, impaired sleep was the only potential mediator of the caregiver effect on cognitive performance in our small sample...
Adherence to yoga and exercise interventions in a 6-month clinical trialK E Flegal
Department of Neurology, Oregon Health and Science University, Portland, USA
BMC Complement Altern Med 7:37. 2007..To determine factors that predict adherence to a mind-body intervention in a randomized trial...
Pilot controlled trial of mindfulness meditation and education for dementia caregiversBarry S Oken
Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
J Altern Complement Med 16:1031-8. 2010..The objectives of this study were to evaluate whether a mindfulness meditation intervention may be effective in caregivers of close relatives with dementia and to help refine the protocol for future larger trials...
Placebo effects: clinical aspects and neurobiologyBarry S Oken
Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
Brain 131:2812-23. 2008..Maximizing this expectancy effect is important for clinicians to optimize the health of their patient. There have been many relatively acute placebo studies that are now being extended into clinically relevant models of placebo effect...
Expectancy effect: impact of pill administration on cognitive performance in healthy seniorsBarry S Oken
Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
J Clin Exp Neuropsychol 30:7-17. 2008..Further characterizing and understanding this observed expectancy effect is important to maximize cognitive health and improve clinical trial design...
The efficacy of Ginkgo biloba on cognitive function in Alzheimer diseaseB S Oken
Department of Neurology, Oregon Health Sciences University, Portland 97201, USA
Arch Neurol 55:1409-15. 1998..To determine the effect of treatment with Ginkgo biloba extract on objective measures of cognitive function in patients with Alzheimer disease (AD) based on formal review of the current literature...
Cognition and fatigue in multiple sclerosis: Potential effects of medications with central nervous system activityBarry S Oken
Department of Neurology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
J Rehabil Res Dev 43:83-90. 2006....
Vigilance, alertness, or sustained attention: physiological basis and measurementB S Oken
Department of Neurology, Oregon Health and Science University OHSU, CR120, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
Clin Neurophysiol 117:1885-901. 2006..This review paper discusses the underlying neural basis of vigilance and its assessment using physiologic tools. Since, assessment of vigilance requires assessment of cognitive function this aspect is also discussed...
Randomized controlled trial of yoga and exercise in multiple sclerosisB S Oken
Department of Neurology, Oregon Health and Science University, Portland 97239, USA
Neurology 62:2058-64. 2004..To determine the effect of yoga and of aerobic exercise on cognitive function, fatigue, mood, and quality of life in multiple sclerosis (MS)...
Randomized, controlled, six-month trial of yoga in healthy seniors: effects on cognition and quality of lifeBarry S Oken
Department of Neurology and Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, USA
Altern Ther Health Med 12:40-7. 2006..Those in the yoga group showed significant improvement in quality-of-life and physical measures compared to exercise and wait-list control groups...
Correlations of Perceived Deficits Questionnaire of Multiple Sclerosis Quality of Life Inventory with Beck Depression Inventory and neuropsychological testsJesus Lovera
Multiple Sclerosis Center of Excellence West, Portland Department of Veterans Affairs VA Medical Center, Portland, OR 97239 2999, USA
J Rehabil Res Dev 43:73-82. 2006..No significant correlations were found between any of these tests and the PDQ. These results suggest that self-perceived cognitive dysfunction relates more to depression than to objective cognitive dysfunction...
Assessment of CNS effects of antiepileptic drugs by using quantitative EEG measuresMartin C Salinsky
Oregon Health and Science University Epilepsy Center, Portland, OR 97239, USA
Epilepsia 44:1042-50. 2003..Objective methods for recognizing AED effects on the brain could be valuable for long-term management. We compared quantitative EEG measures and cognitive tests in a group of patients beginning or ending AED therapy...
Salivary cortisol awakening response in mild Alzheimer disease, caregivers, and noncaregiversHELANE WAHBEH
Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
Alzheimer Dis Assoc Disord 22:181-3. 2008..Salivary cortisol and cortisol response on awakening may enhance future studies relating free cortisol to subjective psychologic and physiologic markers...
A randomized pilot study of naturopathic medicine in multiple sclerosisLynne Shinto
Department of Neurology, Oregon Health and Science University, Portland, OR 97239 3098, USA
J Altern Complement Med 14:489-96. 2008..Naturopathic medicine encompasses a broad range of CAM modalities and may improve quality of life in patients with MS...
Assessing sleep architecture in dementia caregivers at home using an ambulatory polysomnographic systemIrina Fonareva
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
J Geriatr Psychiatry Neurol 24:50-9. 2011..Our findings indicate that sleep disruption is a significant concomitant of caregiving and may affect caregiver's health. Sleep quality of caregivers might be a useful target for a clinical intervention...
Differences in stress-related ratings between research center and home environments in dementia caregivers using ecological momentary assessmentIrina Fonareva
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97239, USA
Int Psychogeriatr 24:90-8. 2012..This study aimed to compare ratings of stress-related measures obtained in research settings and in the home using ecological momentary assessment (EMA)...
Reliability and validity of food frequency questionnaire and nutrient biomarkers in elders with and without mild cognitive impairmentGene L Bowman
Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
Alzheimer Dis Assoc Disord 25:49-57. 2011..Our study objective was to examine the reliability and validity of the 2 common nutritional assessments (plasma nutrient biomarkers and Food Frequency Questionnaire) in the people at risk for dementia...
Ascorbic acid and rates of cognitive decline in Alzheimer's diseaseGene L Bowman
Department of Neurology, Oregon Health and Science University, Portland, OR, USA
J Alzheimers Dis 16:93-8. 2009..This relationship may indicate that the CSF: plasma AA ratio is an index of AA availability to the brain or may be an artifact of a relationship between blood-brain barrier impairment and neurodegeneration...
Comparisons of plasma/serum micronutrients between Okinawan and Oregonian elders: a pilot studyHiroko H Dodge
Department of Neurology, Oregon Health and Science University, Portland, OR 97239 3098, USA
J Gerontol A Biol Sci Med Sci 65:1060-7. 2010....
Second generation complementary and alternative medicine physiologic data collection and monitoring research platformRoger M Ellingson
RM Ellingson System Design and Development, 8515 SW Barnes Road, Portland, OR 97225, USA
Conf Proc IEEE Eng Med Biol Soc 2008:1270-3. 2008..The system was designed specifically to support the needs of investigators studying CAM mind-body interventions but could be used for a variety of research needs...
Effects of oxcarbazepine and phenytoin on the EEG and cognition in healthy volunteersM C Salinsky
Department of Neurology, Oregon Health and Science University, Portland, OR 97201, USA
Epilepsy Behav 5:894-902. 2004..The only significant difference between AEDs was for the POMS-Vigor scale, favoring OXC. The small sample size may have contributed to the lack of significant differences between AEDs...
Effects of topiramate and gabapentin on cognitive abilities in healthy volunteersM C Salinsky
Oregon Health and Science University, Portland, OR, USA
Neurology 64:792-8. 2005..To evaluate the cognitive effects of topiramate (TPM) and gabapentin (GBP)...
Cortical excitability and age-related volumetric MRI changesL C Silbert
Department of Neurology, Layton Aging and Alzheimer s Disease Center, Oregon Health and Science University, Portland, OR 97201, USA
Clin Neurophysiol 117:1029-36. 2006..Information regarding cortical excitability in neurologically intact elderly would augment our understanding of the pathophysiology of aging and assist in the interpretation of TMS studies involving elderly subjects...
24 hour ambulatory research system supporting multiple physiologic sensorsRoger M Ellingson
Ellingson Syst Design and Dev, Portland, OR 97255, USA
Conf Proc IEEE Eng Med Biol Soc 1:5928-31. 2006..Experience with data acquisition and methods for post-acquisition data analysis are also discussed...
Patterns of dietary supplement usage in demographically diverse older peopleShirley S Kishiyama
Department of Neurology, Oregon Health and Science University, Portland, Oregon, USA
Altern Ther Health Med 11:48-53. 2005..Researchers and clinicians should be aware of this pattern and potential conflicts with research design or treatment regimen intended for older people...
Sensitivity to mental effort and test-retest reliability of heart rate variability measures in healthy seniorsShalini Mukherjee
Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
Clin Neurophysiol 122:2059-66. 2011....
Effects of gabapentin and carbamazepine on the EEG and cognition in healthy volunteersMartin C Salinsky
Oregon Health Sciences University Epilepsy Center, Portland, Oregon 97201, USA
Epilepsia 43:482-90. 2002..Objective methods for detection of neurotoxicity in individual patients would be useful. We studied the effects of gabapentin (GBP) and carbamazepine (CBZ) on neurophysiologic and cognitive/behavioral measures in healthy volunteers...
Nicotine effects on alertness and spatial attention in non-smokersWilliam S Griesar
Department of Behavioral Neuroscience CR 120, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
Nicotine Tob Res 4:185-94. 2002..However, nicotine significantly improved both EEG and self-rated measures of alertness. We conclude that nicotine increases alertness in non-smokers, but we found no improvement in spatial attention using a covert orienting task...
Salivary cortisol lower in posttraumatic stress disorderHELANE WAHBEH
Department of Neurology, Oregon Health and Science University, Portland, Oregon, USA
J Trauma Stress 26:241-8. 2013..The 4-factor avoidance PTSD symptom cluster was associated with cortisol, but not the other symptom clusters. This study supports the finding that cortisol is lower in people with PTSD...
Peak high-frequency HRV and peak alpha frequency higher in PTSDHELANE WAHBEH
Department of Neurology, Oregon Health and Science University, Portland, OR 97239, USA
Appl Psychophysiol Biofeedback 38:57-69. 2013..All other EEG and HRV measures and respiration were not different between groups. Peak high-frequency HRV and peak alpha frequency are sensitive to PTSD status and may be potential biofeedback parameters for future PTSD clinical trials...
Mind-body interventions: applications in neurologyHELANE WAHBEH
Department of Neurology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Mail Code CR120, Portland, OR 97239, USA
Neurology 70:2321-8. 2008..The objective of this article is to give a clinical overview of mind-body interventions and their applications in neurology...
Methylphenidate increases the motor effects of L-Dopa in Parkinson's disease: a pilot studyR Camicioli
Department of Neurology, Oregon Health Sciences University, Portland, Oregon, USA
Clin Neuropharmacol 24:208-13. 2001..Methylphenidate increased the motor effects of L-Dopa with minimal effects on cognitive or affective functions, suggesting a physiologic role for the dopamine transporter in patients with PD with motor fluctuations...
Sleeping and driving: Not a safe dual-taskBarry S Oken
Clin Neurophysiol 118:1899-900. 2007
Research Grants
- Core -- Assessment CoreBarry Oken; Fiscal Year: 2004..abstract_text> ..
- CAM Research Training in Neuroscience & StressBarry Oken; Fiscal Year: 2007....
