Genomes and Genes
Affiliation: Oregon Health and Science University
- Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesisTamilla Nechiporuk
Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, C3 168, Seattle, WA 98109, USA Electronic address
Dev Biol 377:375-84. 2013..These results identify Dlg5 as a regulator of apical polarity complexes and uncover the critical function of Dlg5 in branching morphogenesis and differentiation of lung progenitor cells...
- Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- miceTamilla Nechiporuk
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Dev Cell 13:338-50. 2007..These findings show that Dlg5 is causally involved in hydrocephalus and renal cysts and reveal that targeted membrane delivery of cadherin-catenin adhesion complexes is critical for cell polarity and epithelial tube maintenance...
- Planar cell polarity planes the inconveniences of cell division into a smooth morphogenetic processTamilla Nechiporuk
Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
Dev Cell 10:153-4. 2006..A recent study demonstrated that cells use the planar cell polarity pathway to reestablish polarity and reintegrate daughter cells into developing tissue...