CATHERINE MORGANS

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. doi request reprint TRPM1: the endpoint of the mGluR6 signal transduction cascade in retinal ON-bipolar cells
    Catherine W Morgans
    Oregon Health and Science University, Ophthalmology, Portland, Oregon, USA
    Bioessays 32:609-14. 2010
  2. pmc Serum TRPM1 autoantibodies from melanoma associated retinopathy patients enter retinal on-bipolar cells and attenuate the electroretinogram in mice
    Wei Hong Xiong
    Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, USA
    PLoS ONE 8:e69506. 2013
  3. pmc TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells
    Catherine W Morgans
    Department of Ophthalmology, Oregon Health and Science University, Portland, OR 97239, USA
    Proc Natl Acad Sci U S A 106:19174-8. 2009
  4. ncbi request reprint Photoreceptor calcium channels: insight from night blindness
    Catherine W Morgans
    Neurological Sciences Institute, Oregon Health and Science University, Beaverton, OR 97006, USA
    Vis Neurosci 22:561-8. 2005
  5. ncbi request reprint Localization of nyctalopin in the mammalian retina
    Catherine W Morgans
    Neurological Sciences Institute, Oregon Health and Science University, Beaverton, 97006, USA
    Eur J Neurosci 23:1163-71. 2006
  6. pmc Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cells
    Catherine W Morgans
    Neurological Sciences Institute, Oregon Health and Science University, Beaverton, OR 97006, USA
    Eur J Neurosci 26:2899-905. 2007
  7. ncbi request reprint Rod bipolar cells and horizontal cells form displaced synaptic contacts with rods in the outer nuclear layer of the nob2 retina
    Philippa R Bayley
    Neurological Sciences Institute, Oregon Health and Science University, West Campus, Beaverton, Oregon 97006, USA
    J Comp Neurol 500:286-98. 2007
  8. pmc R9AP stabilizes RGS11-G beta5 and accelerates the early light response of ON-bipolar cells
    Brett G Jeffrey
    Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon 97006, USA
    Vis Neurosci 27:9-17. 2010
  9. pmc Loss of the Synaptic Vesicle Protein SV2B results in reduced neurotransmission and altered synaptic vesicle protein expression in the retina
    Catherine W Morgans
    Casey Eye Institute, Oregon Health and Sciences University, Portland, OR, USA
    PLoS ONE 4:e5230. 2009
  10. ncbi request reprint Distribution of group-III metabotropic glutamate receptors in the retina
    Salma Quraishi
    Neurological Sciences Institute, Oregon Health and Science University, Beaverton, Oregon 97006, USA
    J Comp Neurol 501:931-43. 2007

Research Grants

  1. Calcium channels at ribbon synapses in the retina
    CATHERINE MORGANS; Fiscal Year: 2007
  2. Signaling mechanisms of retinal bipolar cells
    Catherine W Morgans; Fiscal Year: 2010
  3. The role of nyctalopin in the mammalian retina
    CATHERINE MORGANS; Fiscal Year: 2006
  4. Signaling mechanisms of retinal bipolar cells
    CATHERINE MORGANS; Fiscal Year: 2009

Collaborators

Detail Information

Publications16

  1. doi request reprint TRPM1: the endpoint of the mGluR6 signal transduction cascade in retinal ON-bipolar cells
    Catherine W Morgans
    Oregon Health and Science University, Ophthalmology, Portland, Oregon, USA
    Bioessays 32:609-14. 2010
    ..Furthermore, expression of TRPM1 in both the retina and skin raises the possibility that a genetic link exists between certain types of visual and skin disorders...
  2. pmc Serum TRPM1 autoantibodies from melanoma associated retinopathy patients enter retinal on-bipolar cells and attenuate the electroretinogram in mice
    Wei Hong Xiong
    Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, USA
    PLoS ONE 8:e69506. 2013
    ....
  3. pmc TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells
    Catherine W Morgans
    Department of Ophthalmology, Oregon Health and Science University, Portland, OR 97239, USA
    Proc Natl Acad Sci U S A 106:19174-8. 2009
    ..Identification of TRPM1 as a mGluR6-coupled cation channel reveals a key step in vision, expands the role of the TRP channel family in sensory perception, and presents insights into the evolution of vertebrate vision...
  4. ncbi request reprint Photoreceptor calcium channels: insight from night blindness
    Catherine W Morgans
    Neurological Sciences Institute, Oregon Health and Science University, Beaverton, OR 97006, USA
    Vis Neurosci 22:561-8. 2005
    ..Lastly, we present evidence for L-type alpha 1D calcium channel subunits in cone terminals of the mouse retina. The presence of alpha 1D channels in cones may explain the residual visual abilities of individuals with CSNB2...
  5. ncbi request reprint Localization of nyctalopin in the mammalian retina
    Catherine W Morgans
    Neurological Sciences Institute, Oregon Health and Science University, Beaverton, 97006, USA
    Eur J Neurosci 23:1163-71. 2006
    ..In the inner plexiform layer, nyctalopin immunoreactivity is associated with rod bipolar cell terminals. Our findings support a role for nyctalopin in synaptic transmission and/or synapse formation at ribbon synapses in the retina...
  6. pmc Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cells
    Catherine W Morgans
    Neurological Sciences Institute, Oregon Health and Science University, Beaverton, OR 97006, USA
    Eur J Neurosci 26:2899-905. 2007
    ....
  7. ncbi request reprint Rod bipolar cells and horizontal cells form displaced synaptic contacts with rods in the outer nuclear layer of the nob2 retina
    Philippa R Bayley
    Neurological Sciences Institute, Oregon Health and Science University, West Campus, Beaverton, Oregon 97006, USA
    J Comp Neurol 500:286-98. 2007
    ....
  8. pmc R9AP stabilizes RGS11-G beta5 and accelerates the early light response of ON-bipolar cells
    Brett G Jeffrey
    Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon 97006, USA
    Vis Neurosci 27:9-17. 2010
    ..Our data indicate that R9AP is required for stable expression of RGS11-Gbeta5 in ON-bipolar cell dendrites. Furthermore, they suggest that the RGS11-Gbeta5-R9AP complex accelerates the initial ON-bipolar cell response to light...
  9. pmc Loss of the Synaptic Vesicle Protein SV2B results in reduced neurotransmission and altered synaptic vesicle protein expression in the retina
    Catherine W Morgans
    Casey Eye Institute, Oregon Health and Sciences University, Portland, OR, USA
    PLoS ONE 4:e5230. 2009
    ..Thus, SV2B contributes to the modulation of synaptic vesicle exocytosis and plays a significant role in regulating synaptic protein content...
  10. ncbi request reprint Distribution of group-III metabotropic glutamate receptors in the retina
    Salma Quraishi
    Neurological Sciences Institute, Oregon Health and Science University, Beaverton, Oregon 97006, USA
    J Comp Neurol 501:931-43. 2007
    ....
  11. pmc Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse
    Lawrence H Pinto
    Department of Neurobiology and Physiology and Center for Functional Genomics, Northwestern University, Evanston, Illinois 60208, USA
    Vis Neurosci 24:111-23. 2007
    ....
  12. pmc The nob2 mouse, a null mutation in Cacna1f: anatomical and functional abnormalities in the outer retina and their consequences on ganglion cell visual responses
    Bo Chang
    The Jackson Laboratory, Bar Harbor, Maine, USA
    Vis Neurosci 23:11-24. 2006
    ..Further, the nob2 mouse represents a model system in which to define the signals that guide synapse formation and/or maintenance in the OPL...
  13. ncbi request reprint Ionic mechanisms mediating oscillatory membrane potentials in wide-field retinal amacrine cells
    Jozsef Vigh
    Department of Ophthalmology and Visual Sciences, John Moran Eye Center, University of Utah, Health Sciences Center, Salt Lake City, Utah 84132, USA
    J Neurophysiol 90:431-43. 2003
    ....
  14. ncbi request reprint Molecular identity, synaptic localization, and physiology of calcium channels in retinal bipolar cells
    Amy Berntson
    John Curtin School of Medical Research, Australian National University, Canberra, Australia
    J Neurosci Res 71:146-51. 2003
    ..The L-type current may be mediated by the alpha(1F) subunit, and influx of calcium through the alpha(1F) channel may control neurotransmitter release from the bipolar cell terminal...
  15. ncbi request reprint Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer
    Sherry L Ball
    Research Service, Cleveland VA Medical Center, Cleveland, Ohio, USA
    Invest Ophthalmol Vis Sci 43:1595-603. 2002
    ..The purpose of this study was to dentify which of the four beta subunits of VDCCs participates in the formation of this channel at the photoreceptor synapse and to determine how its absence affects visual processing...
  16. ncbi request reprint Distribution of the presynaptic calcium sensors, synaptotagmin I/II and synaptotagmin III, in the goldfish and rodent retinas
    Amy K Berntson
    Howard Hughes Medical Institute and Harvard Medical School, Boston, MA, USA
    J Vis 3:274-80. 2003
    ..These results suggest that, unlike in their mammalian counterparts, synaptic vesicle exocytosis in goldfish photoreceptor and bipolar cell terminals utilizes a calcium sensor other than Syt I/II, possibly Syt III...

Research Grants8

  1. Calcium channels at ribbon synapses in the retina
    CATHERINE MORGANS; Fiscal Year: 2007
    ..The results of these experiments will provide insight into the composition and functional organization of retinal ribbon synapses and into the perturbation of retinal function associated with CSNB2. ..
  2. Signaling mechanisms of retinal bipolar cells
    Catherine W Morgans; Fiscal Year: 2010
    ....
  3. The role of nyctalopin in the mammalian retina
    CATHERINE MORGANS; Fiscal Year: 2006
    ..These results will provide insight into the role of nyctalopin in synaptic transmission between photoreceptors and ON-BPCs in the retina, and may lead to the identification of other components of the ON-BPC pathway. ..
  4. Signaling mechanisms of retinal bipolar cells
    CATHERINE MORGANS; Fiscal Year: 2009
    ....