Research Topics
| Suzanne H MitchellSummaryAffiliation: Oregon Health and Science University Country: USA Publications
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Detail Information
Publications
Effects of short-term nicotine deprivation on decision-making: delay, uncertainty and effort discountingSuzanne H Mitchell
University of New Hampshire, USA
Nicotine Tob Res 6:819-28. 2004..Decision-making in the other tasks followed a similar pattern: Deprivation increased preference for the cigarette alternative but did not alter the decision-making processes for nondrug rewards...
Delay discounting predicts behavioral sensitization to ethanol in outbred WSC miceSuzanne H Mitchell
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97239, USA
Alcohol Clin Exp Res 30:429-37. 2006....
Global and local morphometric differences in recently abstinent methamphetamine-dependent individualsDaniel L Schwartz
Research Service, Portland Veterans Affairs Medical Center, Portland, OR, USA
Neuroimage 50:1392-401. 2010..The findings are consistent with multiple possible mechanisms including neuroadaptations due to addictive behavior, neuroinflammation as well as dopaminergic and serotonergic neurotoxicity...
Discounting of delayed rewards and executive dysfunction in individuals infected with hepatitis CMarilyn Huckans
Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, OR 97239, USA
J Clin Exp Neuropsychol 33:176-86. 2011....
Mouse lines selected for alcohol consumption differ on certain measures of impulsivityClare J Wilhelm
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97239, USA
Alcohol Clin Exp Res 31:1839-45. 2007..The aim of this study was to examine the role of genetics by comparing impulsivity in short-term selected lines of mice bred to voluntarily drink either high (STDRHI2) or low (STDRLO2) amounts of 10% ethanol...
Measuring impulsivity and modeling its association with cigarette smokingSuzanne H Mitchell
Department of Behavioral Neuroscience, Oregon Health and Science University, USA
Behav Cogn Neurosci Rev 3:261-75. 2004..However, pertinent studies are limited and additional systematic research is needed...
Differences in delay discounting between smokers and nonsmokers remain when both rewards are delayedSuzanne H Mitchell
Department of Behavioral Neuroscience, L470, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
Psychopharmacology (Berl) 219:549-62. 2012..That is, smokers discount the value of the LargeLater reward more than nonsmokers...
Impact of strain and D-amphetamine on impulsivity (delay discounting) in inbred miceChrista M Helms
Department of Behavioral Neuroscience L 470, Oregon Health and Science University, Portland, OR 97239, USA
Psychopharmacology (Berl) 188:144-51. 2006..C57BL/6J (B6) and DBA/2J (D2) mouse strains differ in sensitivity to the associative effects and in self-administration of several drugs of abuse...
Strain differences in behavioral inhibition in a Go/No-go task demonstrated using 15 inbred mouse strainsNoah R Gubner
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97239, USA
Alcohol Clin Exp Res 34:1353-62. 2010..High levels of impulsivity have been associated with a number of substance abuse disorders including alcohol abuse. Research has not yet revealed whether these high levels predate the development of alcohol abuse...
Cortical activation during delay discounting in abstinent methamphetamine dependent individualsWilliam F Hoffman
Mental Health and Clinical Neurosciences Division P35C, Veterans Affairs Medical Center, 3710 SW US Veterans Hospital Road, Portland, OR 97239, USA
Psychopharmacology (Berl) 201:183-93. 2008..The ventral system is hypothesized to respond to the salience and immediacy of rewards while the dorsal system is implicated in the process of comparison and choice...
Response bias is unaffected by delay length in a delay discounting paradigmClare J Wilhelm
Department of Psychiatry, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, United States
Behav Processes 84:445-9. 2010..These results indicate that response bias was stable and suggests a relative aversion for the adjusting alternative, which may be due to the variability in reward size associated with that alternative...
Behavioral inhibition in mice bred for high vs. low levels of methamphetamine consumption or sensitizationTravis M Moschak
Department of Behavioral Neuroscience L470, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
Psychopharmacology (Berl) 222:353-65. 2012..Other studies have suggested that heightened levels of impulsivity, including low levels of behavioral inhibition, are associated with the use of drugs, including MA...
Acute ethanol does not always affect delay discounting in rats selected to prefer or avoid ethanolClare J Wilhelm
Department of Psychiatry, Oregon Health and Science University, Portland, OR 97239, USA
Alcohol Alcohol 47:518-24. 2012..The purpose of this study was to determine whether animals predisposed to prefer alcohol possess an altered acute response to alcohol on a delay discounting task relative to animals predisposed to avoid alcohol...
Gender differences in factors associated with alcohol drinking: delay discounting and perception of others' drinkingRachelle L Yankelevitz
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
Drug Alcohol Depend 123:273-6. 2012..We examined whether moderate drinkers discount alcohol rewards differently from money rewards and whether their estimate of others' drinking is more closely associated with own-drinking for males than females...
Mechanisms underlying heightened risk taking in adolescents as compared with adultsSuzanne H Mitchell
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97239, USA
Psychon Bull Rev 15:272-7. 2008....
Basolateral amygdala lesions and sensitivity to reinforcer magnitude in concurrent chains schedulesChrista M Helms
Oregon Health and Science University, Oregon National Primate Research Center, Division of Neuroscience, L 584, 505 N W 185th Avenue, Beaverton, OR 97006, USA
Behav Brain Res 191:210-8. 2008..Impaired learning about the tone-reinforcer magnitude relationships may have disrupted discrimination of the reinforcer magnitude reversal...
Delay discounting of reward in ADHD: application in young childrenVanessa B Wilson
Department of Behavioral Neuroscience Department of Psychiatry, Oregon Health and Science University, USA Department of Psychology, University of Oregon, USA
J Child Psychol Psychiatry 52:256-64. 2011..This study examines whether children with ADHD discount the value of delayed rewards to a greater degree than typically developing children using a delay discounting task...
The genetic basis of delay discounting and its genetic relationship to alcohol dependenceSuzanne H Mitchell
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, United States
Behav Processes 87:10-7. 2011..The identities of the genes in this network are not yet known, but research examining polymorphisms associated with differences in discounting is beginning to address this issue...
Dopamine D2 receptors mediate reversal learning in male C57BL/6J micePaul J Kruzich
Oregon Health and Science University, Portland, Oregon 97239, USA
Cogn Affect Behav Neurosci 6:86-90. 2006..Our results suggest that dopamine D2 receptors regulate reversal learning and influence the reinforcing efficacy of natural rewards...
Neuropsychological function and delay discounting in methamphetamine-dependent individualsWilliam F Hoffman
Mental Health and Clinical Neurosciences Division and Methamphetamine Abuse Research Center P35C, Veterans Affairs Medical Center, and Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
Psychopharmacology (Berl) 188:162-70. 2006..Methamphetamine (MA) dependence accounts for substantial neuropsychiatric morbidity. Furthermore, there is evidence in the literature of psychiatric and cognitive impairment in chronic users...
The role of antipsychotics in smoking and smoking cessationAnnette M Matthews
Research and Development Service, Portland VA Medical Center, Portland, Oregon, USA
CNS Drugs 25:299-315. 2011..Gaps in the research are noted and recommendations for further study are included. More study of this important issue is needed to clarify the effect of antipsychotics on smoking behaviours...
Delay discounting behavior and white matter microstructure abnormalities in youth with a family history of alcoholismMegan M Herting
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon 97239, USA
Alcohol Clin Exp Res 34:1590-602. 2010..The current study examined delay discounting behavior and white matter microstructure in youth at high risk for alcohol abuse, as determined by a family history of alcoholism (FH+), and youth without such family history (FH-)...
The subjective value of delayed and probabilistic outcomes: Outcome size matters for gains but not for lossesSuzanne H Mitchell
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, United States
Behav Processes 83:36-40. 2010..These results suggest that the processes underlying the subjective valuation of losses are different from those underlying the subjective valuation of gains...
Acute ethanol administration and reinforcer magnitude reduction both reduce responding and increase response latency in a go/no-go taskTravis M Moschak
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239 3098, USA
Alcohol Clin Exp Res 36:1803-10. 2012..Few studies have examined EtOH's effects on behavioral inhibition in animals, and those that have done so have used Go/No-Go tasks in which no warning cue was provided...
