Alexander J Michels

Summary

Affiliation: Oregon State University
Country: USA

Publications

  1. pmc Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research
    Alexander J Michels
    Linus Pauling Institute, 307 Linus Pauling Science Center, Oregon State University, Corvallis, OR 97331, USA
    Nutrients 5:5161-92. 2013
  2. doi request reprint Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function
    Alexander J Michels
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
    Annu Rev Nutr 33:45-70. 2013
  3. pmc Hepatocyte nuclear factor 1 is essential for transcription of sodium-dependent vitamin C transporter protein 1
    Alexander J Michels
    Linus Pauling Institute and the Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, USA
    Am J Physiol Cell Physiol 297:C1220-7. 2009
  4. doi request reprint Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response
    Kate Petersen Shay
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
    Biochim Biophys Acta 1823:1102-9. 2012
  5. ncbi request reprint Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes
    Alexander J Michels
    Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, 571 Weniger Hall, Corvallis, OR 97331, USA
    Arch Biochem Biophys 410:112-20. 2003
  6. pmc (R)-α-Lipoic acid treatment restores ceramide balance in aging rat cardiac mitochondria
    Jeffrey S Monette
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
    Pharmacol Res 63:23-9. 2011
  7. doi request reprint Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity
    Meltem Yilmazer-Musa
    Linus Pauling Institute, Oregon State University, Corvallis, Oregon 97331, USA
    J Agric Food Chem 60:8924-9. 2012

Collaborators

Detail Information

Publications7

  1. pmc Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research
    Alexander J Michels
    Linus Pauling Institute, 307 Linus Pauling Science Center, Oregon State University, Corvallis, OR 97331, USA
    Nutrients 5:5161-92. 2013
    ..Only with careful attention to study design and experimental detail can we further our understanding of the possible roles of vitamin C in promoting human health and preventing or treating disease. ..
  2. doi request reprint Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function
    Alexander J Michels
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
    Annu Rev Nutr 33:45-70. 2013
    ..We conclude that future epidemiological studies should take into account genetic variation in order to successfully determine the role of vitamin C nutriture or supplementation in human vitamin C status and chronic disease risk. ..
  3. pmc Hepatocyte nuclear factor 1 is essential for transcription of sodium-dependent vitamin C transporter protein 1
    Alexander J Michels
    Linus Pauling Institute and the Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, USA
    Am J Physiol Cell Physiol 297:C1220-7. 2009
    ..Together, these data suggest that HNF-1alpha and/or HNF-1beta binding is required for SVCT1 expression and may be involved in the coordinate regulation of whole body vitamin C status...
  4. doi request reprint Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response
    Kate Petersen Shay
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
    Biochim Biophys Acta 1823:1102-9. 2012
    ..Thus, translational control of Nrf2 synthesis, rather than reliance solely on pre-existing protein, may mediate the rapid burst of Nrf2 nuclear accumulation following stress stimuli...
  5. ncbi request reprint Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes
    Alexander J Michels
    Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, 571 Weniger Hall, Corvallis, OR 97331, USA
    Arch Biochem Biophys 410:112-20. 2003
    ..These results show for the first time that sodium-dependent AA transport declines during the aging process, which may account for much of the loss in tissue AA content...
  6. pmc (R)-α-Lipoic acid treatment restores ceramide balance in aging rat cardiac mitochondria
    Jeffrey S Monette
    Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA
    Pharmacol Res 63:23-9. 2011
    ..In summary, LA treatment lowers ceramide levels to that seen in young rat heart mitochondria and restores Complex IV activity which otherwise declines with age...
  7. doi request reprint Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity
    Meltem Yilmazer-Musa
    Linus Pauling Institute, Oregon State University, Corvallis, Oregon 97331, USA
    J Agric Food Chem 60:8924-9. 2012
    ....