James A McCormick

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. pmc A SPAK isoform switch modulates renal salt transport and blood pressure
    James A McCormick
    Division of Nephrology and Hypertension, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Cell Metab 14:352-64. 2011
  2. pmc The WNKs: atypical protein kinases with pleiotropic actions
    James A McCormick
    Division of Nephrology and Hypertension, Oregon Health and Science University and Veterans Affairs Medical Center, Portland, Oregon 97239, USA
    Physiol Rev 91:177-219. 2011
  3. pmc Overexpression of the sodium chloride cotransporter is not sufficient to cause familial hyperkalemic hypertension
    James A McCormick
    Division of Nephrology and Hypertension, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Mail Code L463, Portland, OR 97239 3098, USA
    Hypertension 58:888-94. 2011
  4. doi request reprint The WNK kinase network regulating sodium, potassium, and blood pressure
    Ewout J Hoorn
    Division of Nephrology and Hypertension, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA
    J Am Soc Nephrol 22:605-14. 2011
  5. pmc Sympathetic stimulation of thiazide-sensitive sodium chloride cotransport in the generation of salt-sensitive hypertension
    Andrew S Terker
    From the Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland A S T, C L Y, J A M, N P M, S L R, D H E Renal Section, VA Medical Center, Portland, OR C L Y, N P M, D H E Institute of Anatomy, University of Zurich, Zurich, Switzerland S G, K T, J L and Department of Anesthesiology, Vanderbilt University Medical School, Nashville, TN E D
    Hypertension 64:178-84. 2014
  6. pmc The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension
    Ewout J Hoorn
    Division of Nephrology and Hypertension, Oregon Health and Science University, Portland, Oregon, USA
    Nat Med 17:1304-9. 2011
  7. pmc Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2
    Hae J Park
    Division of Nephrology and Hypertension, Dept of Medicine, Oregon Health and Science Univ, 3181 SW Sam Jackson Park Road, L463, Portland, Oregon 97239 2940
    Am J Physiol Renal Physiol 305:F1687-96. 2013
  8. pmc High tail-cuff blood pressure in mice 1 week after shipping: the need for longer acclimation
    Ewout J Hoorn
    Division of Nephrology and Hypertension, Oregon Health and Science University, Portland, USA
    Am J Hypertens 24:534-6. 2011
  9. pmc Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride
    Andrew S Terker
    Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, OR 97239, USA
    Cell Metab 21:39-50. 2015
  10. pmc WNK kinases and renal sodium transport in health and disease: an integrated view
    James A McCormick
    Division of Nephrology and Hypertension and Heart Research Center, Department of Medicine, Oregon Health and Science University, Portland, OR 97239, USA
    Hypertension 51:588-96. 2008

Collaborators

  • Chao Ling Yang
  • Johannes Loffing
  • Stephen B Walsh
  • Eric Delpire
  • Ewout J Hoorn
  • David H Ellison
  • Andrew S Terker
  • Hae J Park
  • Nicholas P Meermeier
  • Yi Fu
  • Chengbiao Zhang
  • David M Cohen
  • Wen Hui Wang
  • Chong Zhang
  • Dominic A Siler
  • Rebecca A Lazelle
  • Alan M Weinstein
  • Katja Trompf
  • Solveig Grossmann
  • Shaunessy L Rogers
  • Joshua N Curry
  • Joshua H Nelson
  • James Conley
  • Alexander Paliege
  • Robert J Unwin
  • Antje F├╝rstenberg
  • Alexander J Howie
  • Sebastian Bachmann
  • Tom Roeschel

Detail Information

Publications11

  1. pmc A SPAK isoform switch modulates renal salt transport and blood pressure
    James A McCormick
    Division of Nephrology and Hypertension, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Cell Metab 14:352-64. 2011
    ..In mice, extracellular fluid volume depletion shifts SPAK isoform abundance to favor NaCl retention along both segments, indicating that a SPAK isoform switch modulates sodium avidity along the distal nephron...
  2. pmc The WNKs: atypical protein kinases with pleiotropic actions
    James A McCormick
    Division of Nephrology and Hypertension, Oregon Health and Science University and Veterans Affairs Medical Center, Portland, Oregon 97239, USA
    Physiol Rev 91:177-219. 2011
    ..Next, consequences of these effects on integrated physiological function are outlined. Finally, we discuss the known and putative pathophysiological relevance of the WNKs...
  3. pmc Overexpression of the sodium chloride cotransporter is not sufficient to cause familial hyperkalemic hypertension
    James A McCormick
    Division of Nephrology and Hypertension, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Mail Code L463, Portland, OR 97239 3098, USA
    Hypertension 58:888-94. 2011
    ....
  4. doi request reprint The WNK kinase network regulating sodium, potassium, and blood pressure
    Ewout J Hoorn
    Division of Nephrology and Hypertension, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA
    J Am Soc Nephrol 22:605-14. 2011
    ..Although many questions remain unanswered, the WNKs hold promise for unraveling the link between salt and hypertension, potentially leading to more effective interventions to prevent cardiorenal damage...
  5. pmc Sympathetic stimulation of thiazide-sensitive sodium chloride cotransport in the generation of salt-sensitive hypertension
    Andrew S Terker
    From the Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland A S T, C L Y, J A M, N P M, S L R, D H E Renal Section, VA Medical Center, Portland, OR C L Y, N P M, D H E Institute of Anatomy, University of Zurich, Zurich, Switzerland S G, K T, J L and Department of Anesthesiology, Vanderbilt University Medical School, Nashville, TN E D
    Hypertension 64:178-84. 2014
    ..The results have implications about device- and drug-based treatment of hypertension...
  6. pmc The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension
    Ewout J Hoorn
    Division of Nephrology and Hypertension, Oregon Health and Science University, Portland, Oregon, USA
    Nat Med 17:1304-9. 2011
    ....
  7. pmc Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2
    Hae J Park
    Division of Nephrology and Hypertension, Dept of Medicine, Oregon Health and Science Univ, 3181 SW Sam Jackson Park Road, L463, Portland, Oregon 97239 2940
    Am J Physiol Renal Physiol 305:F1687-96. 2013
    ..Together, these data identify the structural basis for the differential effects of KS-SPAK and SPAK2 on cation cotransporter activity that may be physiologically important. ..
  8. pmc High tail-cuff blood pressure in mice 1 week after shipping: the need for longer acclimation
    Ewout J Hoorn
    Division of Nephrology and Hypertension, Oregon Health and Science University, Portland, USA
    Am J Hypertens 24:534-6. 2011
    ..For vendor-derived mice, an acclimation period of 1 week is usually recommended before blood pressure measurements are started. However, we observed hypertension in wild-type vendor-derived mice 1 week after shipping...
  9. pmc Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride
    Andrew S Terker
    Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, OR 97239, USA
    Cell Metab 21:39-50. 2015
    ..In the DCT, hyperpolarization activates NCC via WNK kinases, whereas in the adrenal gland, it inhibits aldosterone secretion. These effects work in concert to maintain potassium homeostasis. ..
  10. pmc WNK kinases and renal sodium transport in health and disease: an integrated view
    James A McCormick
    Division of Nephrology and Hypertension and Heart Research Center, Department of Medicine, Oregon Health and Science University, Portland, OR 97239, USA
    Hypertension 51:588-96. 2008
  11. doi request reprint Distal convoluted tubule
    James A McCormick
    Division of Nephrology and Hypertension, Oregon Health and Science University, and VA Medical Center, Portland, Oregon, United States
    Compr Physiol 5:45-98. 2015
    ..Regulation of expression and activity of these channels and transporters is also described; particular emphasis is placed on the contribution of genetic forms of DCT dysregulation to our understanding...