Kathy Magnusson

Summary

Affiliation: Oregon State University
Country: USA

Publications

  1. pmc Selective Vulnerabilities of N-methyl-D-aspartate (NMDA) Receptors During Brain Aging
    Kathy R Magnusson
    Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University Corvallis, OR, USA
    Front Aging Neurosci 2:11. 2010
  2. pmc The effects of aging and genotype on NMDA receptor expression in growth hormone receptor knockout (GHRKO) mice
    Kathy Ruth Magnusson
    Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, 105 Magruder Hall, Corvallis, OR 97331, USA
    J Gerontol A Biol Sci Med Sci 66:607-19. 2011
  3. pmc Age-related declines in a two-day reference memory task are associated with changes in NMDA receptor subunits in mice
    Kathy R Magnusson
    Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331, USA
    BMC Neurosci 8:43. 2007
  4. ncbi request reprint Age-related deficits in mice performing working memory tasks in a water maze
    Kathy R Magnusson
    Department of Biomedical Sciences, Colorado State University, USA
    Behav Neurosci 117:485-95. 2003
  5. pmc Relationship between mRNA expression of splice forms of the zeta1 subunit of the N-methyl-D-aspartate receptor and spatial memory in aged mice
    Siba R Das
    Molecular and Cellular Biology Program and Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331, USA
    Brain Res 1207:142-54. 2008
  6. ncbi request reprint Changes in the expression of the NR2B subunit during aging in macaque monkeys
    Ling Bai
    Program in Molecular, Cellular, and Integrative Neurosciences, Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Neurobiol Aging 25:201-8. 2004
  7. ncbi request reprint Acute dissociation for analyses of NMDA receptor function in cortical neurons during aging
    M Cathleen Kuehl-Kovarik
    Department of Biomedical Sciences, Anatomy Section, Colorado State University, Fort Collins, CO 80523 1680, USA
    J Neurosci Methods 129:11-7. 2003
  8. pmc Zinc supplementation increases zinc status and thymopoiesis in aged mice
    Carmen P Wong
    Department of Nutrition and Exercise Sciences, Oregon State University, OR 97331, USA
    J Nutr 139:1393-7. 2009
  9. doi request reprint Aging is associated with altered dendritic cells subset distribution and impaired proinflammatory cytokine production
    Carmen P Wong
    Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis, OR 97331, USA
    Exp Gerontol 45:163-9. 2010
  10. ncbi request reprint The effects of aging on different C-terminal splice forms of the zeta1(NR1) subunit of the N-methyl-d-aspartate receptor in mice
    Kathy R Magnusson
    Department of Biological Sciences, WWAMI Medical Program, University of Idaho, Moscow, ID 83844 3051, USA
    Brain Res Mol Brain Res 135:141-9. 2005

Research Grants

Collaborators

  • Peter R Patrylo
  • Xue Zhao
  • David G Standaert
  • P R Hof
  • Carmen P Wong
  • Emily Ho
  • Siba R Das
  • Nicholas R Natale
  • Ling Bai
  • M Cathleen Kuehl-Kovarik
  • Heike M Newman
  • Valerie D Elias
  • Yang Song
  • Jared K Nelson
  • Scott E Nelson
  • Anne B Young
  • Yiding Xing
  • Kathryn M Partin
  • Raymond S H Yang

Detail Information

Publications12

  1. pmc Selective Vulnerabilities of N-methyl-D-aspartate (NMDA) Receptors During Brain Aging
    Kathy R Magnusson
    Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University Corvallis, OR, USA
    Front Aging Neurosci 2:11. 2010
    ..However, we need to be mindful of the possibility that there may also be negative consequences in aged individuals...
  2. pmc The effects of aging and genotype on NMDA receptor expression in growth hormone receptor knockout (GHRKO) mice
    Kathy Ruth Magnusson
    Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, 105 Magruder Hall, Corvallis, OR 97331, USA
    J Gerontol A Biol Sci Med Sci 66:607-19. 2011
    ..These results suggest that some of the functional improvements in aged mice with altered growth hormone signaling may be due to enhancement of NMDA receptors, but not through the upregulation of messenger RNA for the GluN1 subunit...
  3. pmc Age-related declines in a two-day reference memory task are associated with changes in NMDA receptor subunits in mice
    Kathy R Magnusson
    Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331, USA
    BMC Neurosci 8:43. 2007
    ..Crude synaptosomes were prepared from prefrontal/frontal cortex and hippocampus of the mice that underwent reference memory testing first. NMDA receptor subunit and syntaxin proteins were analyzed with Western blotting...
  4. ncbi request reprint Age-related deficits in mice performing working memory tasks in a water maze
    Kathy R Magnusson
    Department of Biomedical Sciences, Colorado State University, USA
    Behav Neurosci 117:485-95. 2003
    ..This increased susceptibility of immediate working memory processes to the aging process in mice may be related to their need for more rehearsal in the water maze than other species...
  5. pmc Relationship between mRNA expression of splice forms of the zeta1 subunit of the N-methyl-D-aspartate receptor and spatial memory in aged mice
    Siba R Das
    Molecular and Cellular Biology Program and Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331, USA
    Brain Res 1207:142-54. 2008
    ..These results suggest that there is a complex interaction between zeta1 splice form expression and performance of memory tasks during aging...
  6. ncbi request reprint Changes in the expression of the NR2B subunit during aging in macaque monkeys
    Ling Bai
    Program in Molecular, Cellular, and Integrative Neurosciences, Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Neurobiol Aging 25:201-8. 2004
    ....
  7. ncbi request reprint Acute dissociation for analyses of NMDA receptor function in cortical neurons during aging
    M Cathleen Kuehl-Kovarik
    Department of Biomedical Sciences, Anatomy Section, Colorado State University, Fort Collins, CO 80523 1680, USA
    J Neurosci Methods 129:11-7. 2003
    ..Thus, this method is ideal for the dissociation of neurons from the brain of both young and old animals, and offers a powerful tool for functional analysis at the level of the individual cell...
  8. pmc Zinc supplementation increases zinc status and thymopoiesis in aged mice
    Carmen P Wong
    Department of Nutrition and Exercise Sciences, Oregon State University, OR 97331, USA
    J Nutr 139:1393-7. 2009
    ..Taken together, our results showed that in mice, zinc supplementation can reverse some age-related thymic defects and may be of considerable benefit in improving immune function and overall health in elderly populations...
  9. doi request reprint Aging is associated with altered dendritic cells subset distribution and impaired proinflammatory cytokine production
    Carmen P Wong
    Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis, OR 97331, USA
    Exp Gerontol 45:163-9. 2010
    ..Taken together, our results suggested that aging was associated with dysregulation in splenic DC activation and subset differentiation, and may represent one of the factors contributing to the decline in immune function with age...
  10. ncbi request reprint The effects of aging on different C-terminal splice forms of the zeta1(NR1) subunit of the N-methyl-d-aspartate receptor in mice
    Kathy R Magnusson
    Department of Biological Sciences, WWAMI Medical Program, University of Idaho, Moscow, ID 83844 3051, USA
    Brain Res Mol Brain Res 135:141-9. 2005
    ..This heterogeneity has implications for producing imbalances in the modulation of the remaining receptors...
  11. ncbi request reprint Effects of developmental exposure to lead, magnesium and zinc mixtures on spatial learning and expression of NMDA receptor subunit mRNA in Fischer 344 rats
    Heike M Newman
    Center for Environmental Toxicology and Technology, Department of Environmental Health, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523 1676, USA
    Toxicol Lett 126:107-19. 2002
    ..Our results showed that exposure to all three metals affected mortality, learning ability and gender-dependent expression patterns of an NMDAR subunit in a different way from that seen with exposure to the individual metals...
  12. ncbi request reprint Can selective ligands for glutamate binding proteins be rationally designed?
    Nicholas R Natale
    301 Renfrew Hall, Department of Chemistry, University of Idaho, Moscow, ID 83844 2343 USA
    Curr Top Med Chem 6:823-47. 2006
    ..The prospects for unraveling cross-reactivity will be weighed in light of a critical comparison of the glutamate binding protein targets...

Research Grants12

  1. SUBUNIT CHANGES IN AGING NMDA RECEPTORS AFFECT MEMORY
    Kathy Magnusson; Fiscal Year: 1999
    ..This information will also enhance our knowledge about the role of specific NMDA receptor subunits in learning and memory processes. ..
  2. SUBUNIT CHANGES IN AGING NMDA RECEPTORS AFFECT MEMORY
    Kathy Magnusson; Fiscal Year: 2009
    ..Understanding how the aging process affects molecules that are involved in learning and memory processes allows us to better design interventions that will improve cognitive performance throughout the lifespan. ..
  3. SUBUNIT CHANGES IN AGING NMDA RECEPTORS AFFECT MEMORY
    Kathy Magnusson; Fiscal Year: 2006
    ..This information will also enhance our knowledge about the role of specific NMDA receptor subunits within specific brain regions in learning and memory. ..
  4. SUBUNIT CHANGES IN AGING NMDA RECEPTORS AFFECT MEMORY
    Kathy Magnusson; Fiscal Year: 2004
    ..This information will also enhance our knowledge about the role of specific NMDA receptor subunits within specific brain regions in learning and memory. ..
  5. SUBUNIT CHANGES IN AGING NMDA RECEPTORS AFFECT MEMORY
    Kathy Magnusson; Fiscal Year: 2005
    ..This information will also enhance our knowledge about the role of specific NMDA receptor subunits within specific brain regions in learning and memory. ..
  6. SUBUNIT CHANGES IN AGING NMDA RECEPTORS AFFECT MEMORY
    Kathy Magnusson; Fiscal Year: 2003
    ..This information will also enhance our knowledge about the role of specific NMDA receptor subunits in learning and memory processes. ..
  7. SUBUNIT CHANGES IN AGING NMDA RECEPTORS AFFECT MEMORY
    Kathy Magnusson; Fiscal Year: 2003
    ..This information will also enhance our knowledge about the role of specific NMDA receptor subunits within specific brain regions in learning and memory. ..
  8. SUBUNIT CHANGES IN AGING NMDA RECEPTORS AFFECT MEMORY
    Kathy Magnusson; Fiscal Year: 2002
    ..This information will also enhance our knowledge about the role of specific NMDA receptor subunits in learning and memory processes. ..
  9. SUBUNIT CHANGES IN AGING NMDA RECEPTORS AFFECT MEMORY
    Kathy Magnusson; Fiscal Year: 2001
    ..This information will also enhance our knowledge about the role of specific NMDA receptor subunits in learning and memory processes. ..
  10. SUBUNIT CHANGES IN AGING NMDA RECEPTORS AFFECT MEMORY
    Kathy Magnusson; Fiscal Year: 2000
    ..This information will also enhance our knowledge about the role of specific NMDA receptor subunits in learning and memory processes. ..
  11. SUBUNIT CHANGES IN AGING NMDA RECEPTORS AFFECT MEMORY
    Kathy R Magnusson; Fiscal Year: 2010
    ..Understanding how the aging process affects molecules that are involved in learning and memory processes allows us to better design interventions that will improve cognitive performance throughout the lifespan. ..