DAVID LEWINSOHN

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. Hartmann N, McMurtrey C, Sorensen M, Huber M, Kurapova R, Coleman F, et al. Riboflavin Metabolism Variation Among Clinical Isolates of Streptococcus pneumoniae Results in Differential Activation of MAIT Cells. Am J Respir Cell Mol Biol. 2018;: pubmed publisher
    ..pneumoniae. These differences are critical in considering the role that MAIT cells play in early responses to pneumococcal infection and determining whether invasive disease will develop. ..
  2. request reprint
    Lewinsohn D, Grotzke J, Heinzel A, Zhu L, Ovendale P, Johnson M, et al. Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway. J Immunol. 2006;177:437-42 pubmed
    ..We conclude that secreted proteins from Mtb can be processed in a BFA- and proteasome-dependent manner, consistent with egress of Ag into the cytosol and subsequent loading of proteasomally derived peptides...
  3. Harriff M, Wolfe L, Swarbrick G, Null M, Cansler M, Canfield E, et al. HLA-E Presents Glycopeptides from the Mycobacterium tuberculosis Protein MPT32 to Human CD8+ T cells. Sci Rep. 2017;7:4622 pubmed publisher
    ..The identification of an immune response that targets a unique mycobacterial modification is novel and may have practical impact in the development of vaccines and diagnostics. ..

Detail Information

Publications3

  1. Hartmann N, McMurtrey C, Sorensen M, Huber M, Kurapova R, Coleman F, et al. Riboflavin Metabolism Variation Among Clinical Isolates of Streptococcus pneumoniae Results in Differential Activation of MAIT Cells. Am J Respir Cell Mol Biol. 2018;: pubmed publisher
    ..pneumoniae. These differences are critical in considering the role that MAIT cells play in early responses to pneumococcal infection and determining whether invasive disease will develop. ..
  2. request reprint
    Lewinsohn D, Grotzke J, Heinzel A, Zhu L, Ovendale P, Johnson M, et al. Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway. J Immunol. 2006;177:437-42 pubmed
    ..We conclude that secreted proteins from Mtb can be processed in a BFA- and proteasome-dependent manner, consistent with egress of Ag into the cytosol and subsequent loading of proteasomally derived peptides...
  3. Harriff M, Wolfe L, Swarbrick G, Null M, Cansler M, Canfield E, et al. HLA-E Presents Glycopeptides from the Mycobacterium tuberculosis Protein MPT32 to Human CD8+ T cells. Sci Rep. 2017;7:4622 pubmed publisher
    ..The identification of an immune response that targets a unique mycobacterial modification is novel and may have practical impact in the development of vaccines and diagnostics. ..