C L Kliethermes

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Validation of a modified mirrored chamber sensitive to anxiolytics and anxiogenics in mice
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Portland Alcohol Research Center, Oregon Health and Science University, VAMC Research R and D 12, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Psychopharmacology (Berl) 169:190-7. 2003
  2. ncbi request reprint Selection for pentobarbital withdrawal severity: correlated differences in withdrawal from other sedative drugs
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University and the Portland Alcohol Research Center, Veterans Affairs Medical Center, c o Portland VA Medical Center, Portland, OR 97239, USA
    Brain Res 1009:17-25. 2004
  3. ncbi request reprint Anxiety-like behavior in mice in two apparatuses during withdrawal from chronic ethanol vapor inhalation
    C L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University and the Portland Alcohol Research Center, VA Medical Center, Portland, Oregon 97239, USA
    Alcohol Clin Exp Res 28:1012-9. 2004
  4. ncbi request reprint Anxiety-like behaviors following chronic ethanol exposure
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Neurosci Biobehav Rev 28:837-50. 2005
  5. ncbi request reprint Home cage activity and ingestive behaviors in mice following chronic ethanol vapor inhalation
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Physiol Behav 85:479-88. 2005
  6. pmc Genetic independence of mouse measures of some aspects of novelty seeking
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University and Portland Alcohol Research Center, Veterans Affairs Medical Center, Portland, OR 97239 3098, USA
    Proc Natl Acad Sci U S A 103:5018-23. 2006
  7. ncbi request reprint Pharmacological and genetic influences on hole-board behaviors in mice
    Christopher L Kliethermes
    Ernest Gallo Clinic and Research Center, University of California San Francisco, Emeryville, CA 94608, USA
    Pharmacol Biochem Behav 85:57-65. 2006

Detail Information

Publications7

  1. ncbi request reprint Validation of a modified mirrored chamber sensitive to anxiolytics and anxiogenics in mice
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Portland Alcohol Research Center, Oregon Health and Science University, VAMC Research R and D 12, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Psychopharmacology (Berl) 169:190-7. 2003
    ..Anxiety is a common disorder in humans that exists in many forms, and animal models of human anxiety are typically employed for the discovery of anxiolytic drugs with human therapeutic potential...
  2. ncbi request reprint Selection for pentobarbital withdrawal severity: correlated differences in withdrawal from other sedative drugs
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University and the Portland Alcohol Research Center, Veterans Affairs Medical Center, c o Portland VA Medical Center, Portland, OR 97239, USA
    Brain Res 1009:17-25. 2004
    ..These results indicate that some of the same genes that affect the severity of withdrawal from pentobarbital also influence ethanol and zolpidem withdrawal, but that diazepam withdrawal may be less influenced by these genes...
  3. ncbi request reprint Anxiety-like behavior in mice in two apparatuses during withdrawal from chronic ethanol vapor inhalation
    C L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University and the Portland Alcohol Research Center, VA Medical Center, Portland, Oregon 97239, USA
    Alcohol Clin Exp Res 28:1012-9. 2004
    ..Ethanol vapor inhalation offers an advantage over liquid diet consumption in that the onset of withdrawal can be temporally controlled more precisely, allowing studies of the development of withdrawal symptoms...
  4. ncbi request reprint Anxiety-like behaviors following chronic ethanol exposure
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland Alcohol Research Center, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA
    Neurosci Biobehav Rev 28:837-50. 2005
    ..In addition, standard anxiolytic drugs should ameliorate the anxiogenic-like effects of withdrawal, preferably in multiple tests of anxiety-like behavior...
  5. ncbi request reprint Home cage activity and ingestive behaviors in mice following chronic ethanol vapor inhalation
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
    Physiol Behav 85:479-88. 2005
    ..Further, even in a relatively severe mouse model of alcohol withdrawal, any decreases in general home cage activity are short-lived...
  6. pmc Genetic independence of mouse measures of some aspects of novelty seeking
    Christopher L Kliethermes
    Department of Behavioral Neuroscience, Oregon Health and Science University and Portland Alcohol Research Center, Veterans Affairs Medical Center, Portland, OR 97239 3098, USA
    Proc Natl Acad Sci U S A 103:5018-23. 2006
    ....
  7. ncbi request reprint Pharmacological and genetic influences on hole-board behaviors in mice
    Christopher L Kliethermes
    Ernest Gallo Clinic and Research Center, University of California San Francisco, Emeryville, CA 94608, USA
    Pharmacol Biochem Behav 85:57-65. 2006
    ..However, the results with the genetically heterogeneous mice and HEB and LEB mice suggest that some aspects of the dopaminergic system are involved in head dipping...