MICHAEL LAWRENCE KENT

Summary

Affiliation: Oregon State University
Country: USA

Publications

  1. pmc Polymerase chain reaction detection of Pseudoloma neurophilia, a common microsporidian of zebrafish (Danio rerio) reared in research laboratories
    Christopher M Whipps
    Center for Fish Disease Research, Department of Microbiology, Oregon State University, Corvallis, USA
    J Am Assoc Lab Anim Sci 45:36-9. 2006
  2. doi request reprint Sensitivity and specificity of histology for diagnoses of four common pathogens and detection of nontarget pathogens in adult Chinook salmon (Oncorhynchus tshawytscha) in fresh water
    Michael L Kent
    Department of Microbiology, Oregon State University, 220 Nash Hall, Corvallis, OR 97331, USA
    J Vet Diagn Invest 25:341-51. 2013
  3. pmc Documented and potential research impacts of subclinical diseases in zebrafish
    Michael L Kent
    Department of Microbiology, Oregon State University, Corvallis, OR 97331, USA
    ILAR J 53:126-34. 2012
  4. ncbi request reprint Review of the sequential development of Loma salmonae (Microsporidia) based on experimental infections of rainbow trout (Oncorhynchus mykiss) and Chinook salmon (O. tshawytscha)
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, Oregon 97331 3404, USA
    Folia Parasitol (Praha) 52:63-8. 2005
  5. ncbi request reprint In vivo and in vitro growth of Mycobacterium marinum at homoeothermic temperatures
    Michael L Kent
    Department of Microbiology, Center for Fish Disease Research, Oregon State University, Corvallis, OR 97331 3804, USA
    FEMS Microbiol Lett 257:69-75. 2006
  6. ncbi request reprint Mycobacteriosis in zebrafish (Danio rerio) research facilities
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, 220 Nash, Oregon State University, Corvallis, OR 97331 3804, USA
    Comp Biochem Physiol C Toxicol Pharmacol 138:383-90. 2004
  7. pmc Recommendations for control of pathogens and infectious diseases in fish research facilities
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Comp Biochem Physiol C Toxicol Pharmacol 149:240-8. 2009
  8. doi request reprint Development and maintenance of a specific pathogen-free (SPF) zebrafish research facility for Pseudoloma neurophilia
    Michael L Kent
    Department of Microbiology, Oregon State University, Corvallis, Oregon, USA
    Dis Aquat Organ 95:73-9. 2011
  9. ncbi request reprint Molecular systematics support the revival of Mycobacterium salmoniphilum (ex Ross 1960) sp. nov., nom. rev., a species closely related to Mycobacterium chelonae
    Christopher M Whipps
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, OR 97331 3404, USA
    Int J Syst Evol Microbiol 57:2525-31. 2007
  10. doi request reprint Pleistophora hyphessobryconis (Microsporidia) infecting zebrafish Danio rerio in research facilities
    Justin L Sanders
    Department of Microbiology, Oregon State University, Corvallis, Oregon 97331, USA
    Dis Aquat Organ 91:47-56. 2010

Research Grants

  1. CONTROL OF DISEASE IN ZEBRAFISH RESEARCH FACILITIES
    Michael Kent; Fiscal Year: 2007
  2. Control of Diseases in Zebrafish Research Facilities
    MICHAEL LAWRENCE KENT; Fiscal Year: 2010

Collaborators

Detail Information

Publications33

  1. pmc Polymerase chain reaction detection of Pseudoloma neurophilia, a common microsporidian of zebrafish (Danio rerio) reared in research laboratories
    Christopher M Whipps
    Center for Fish Disease Research, Department of Microbiology, Oregon State University, Corvallis, USA
    J Am Assoc Lab Anim Sci 45:36-9. 2006
    ..Furthermore, we currently are using this PCR method to investigate the potential role of vertical transmission in the spread of P. neurophilia...
  2. doi request reprint Sensitivity and specificity of histology for diagnoses of four common pathogens and detection of nontarget pathogens in adult Chinook salmon (Oncorhynchus tshawytscha) in fresh water
    Michael L Kent
    Department of Microbiology, Oregon State University, 220 Nash Hall, Corvallis, OR 97331, USA
    J Vet Diagn Invest 25:341-51. 2013
    ..salmonicida. Kappa analysis for agreement between Blue Book and histology methods was poor to moderate. However, histological observations revealed the presence of other pathogens that would not be detected by other methods...
  3. pmc Documented and potential research impacts of subclinical diseases in zebrafish
    Michael L Kent
    Department of Microbiology, Oregon State University, Corvallis, OR 97331, USA
    ILAR J 53:126-34. 2012
    ..Understanding the cause, modes of transmission, and distribution of the pathogens would provide useful information for the development of control and prevention strategies...
  4. ncbi request reprint Review of the sequential development of Loma salmonae (Microsporidia) based on experimental infections of rainbow trout (Oncorhynchus mykiss) and Chinook salmon (O. tshawytscha)
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, Oregon 97331 3404, USA
    Folia Parasitol (Praha) 52:63-8. 2005
    ..Autoinfection probably occurs following release of spores in blood vessels after xenomas rupture. The optimal temperature for L. salmonae infections is 15-17 degrees C, with a permissive range of 11-20 degrees C...
  5. ncbi request reprint In vivo and in vitro growth of Mycobacterium marinum at homoeothermic temperatures
    Michael L Kent
    Department of Microbiology, Center for Fish Disease Research, Oregon State University, Corvallis, OR 97331 3804, USA
    FEMS Microbiol Lett 257:69-75. 2006
    ..Significant differences of growth in vitro and in vivo were observed. All fish strains caused both footpad and deep tissue infections, and two, which grew very poorly or not all at 37 degrees C, proliferated in mammalian macrophages...
  6. ncbi request reprint Mycobacteriosis in zebrafish (Danio rerio) research facilities
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, 220 Nash, Oregon State University, Corvallis, OR 97331 3804, USA
    Comp Biochem Physiol C Toxicol Pharmacol 138:383-90. 2004
    ..peregrinum) may pose significant health problems in zebrafish research facilities, whereas species and strains that are already recognized as common in fish usually cause limited disease on a population basis in zebrafish...
  7. pmc Recommendations for control of pathogens and infectious diseases in fish research facilities
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, OR 97331, USA
    Comp Biochem Physiol C Toxicol Pharmacol 149:240-8. 2009
    ..Nevertheless, the goal of documenting, detecting, and excluding pathogens in fish is just as important as in mammalian research models...
  8. doi request reprint Development and maintenance of a specific pathogen-free (SPF) zebrafish research facility for Pseudoloma neurophilia
    Michael L Kent
    Department of Microbiology, Oregon State University, Corvallis, Oregon, USA
    Dis Aquat Organ 95:73-9. 2011
    ..neurophilia. Thus, we have established 9 lines of zebrafish SPF for P. neurophilia. However, 26 fish exhibited mycobacteriosis, with acid-fast bacteria present in tissue sections, and 49 other fish had incidental lesions...
  9. ncbi request reprint Molecular systematics support the revival of Mycobacterium salmoniphilum (ex Ross 1960) sp. nov., nom. rev., a species closely related to Mycobacterium chelonae
    Christopher M Whipps
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, OR 97331 3404, USA
    Int J Syst Evol Microbiol 57:2525-31. 2007
    ..salmoniphilum' as Mycobacterium salmoniphilum (ex Ross 1960) sp. nov., nom. rev., with the type strain SCT (=ATCC 13578T =DSM 43276T)...
  10. doi request reprint Pleistophora hyphessobryconis (Microsporidia) infecting zebrafish Danio rerio in research facilities
    Justin L Sanders
    Department of Microbiology, Oregon State University, Corvallis, Oregon 97331, USA
    Dis Aquat Organ 91:47-56. 2010
    ..hyphessobryconis should be added to the list of pathogens that should be avoided in zebrafish research facilities, and it would be prudent to avoid mixing zebrafish used in research with other aquarium fishes...
  11. ncbi request reprint Pathogenesis of Mycobacterium spp. in zebrafish (Danio rerio) from research facilities
    Virginia Watral
    Center for Fish Disease Research, Department of Microbiology, Oregon State University, Corvallis, OR 97331 3804, USA
    Comp Biochem Physiol C Toxicol Pharmacol 145:55-60. 2007
    ..marinum, and from only 9% of fish exposed to the other species. This study suggests that, of the isolates tested, only M. marinum is highly pathogenic and virulent to healthy zebrafish...
  12. ncbi request reprint Spores of two fish microsporidia (Pseudoloma neurophilia and Glugea anomala) are highly resistant to chlorine
    Jayde A Ferguson
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, Oregon 97331 3404, USA
    Dis Aquat Organ 76:205-14. 2007
    ..neurophilia to progeny...
  13. ncbi request reprint Phylogeography of the cosmopolitan marine parasite Kudoa thyrsites (Myxozoa: Myxosporea)
    Christopher M Whipps
    Center for Fish Disease Research, Department of Microbiology, 220 Nash Hall, Oregon State University, Corvallis, Oregon 97331 3404, USA
    J Eukaryot Microbiol 53:364-73. 2006
    ..Our data also indicate that K. histolytica is not a valid species, as it was morphologically and genetically indistinguishable from K. thyrsites...
  14. pmc Species of environmental mycobacteria differ in their abilities to grow in human, mouse, and carp macrophages and with regard to the presence of mycobacterial virulence genes, as observed by DNA microarray hybridization
    Melanie J Harriff
    Department of Biomedical Sciences, College of Veterinary Medicine, 105 Magruder, Oregon State University, Corvallis, OR 97331, USA
    Appl Environ Microbiol 74:275-85. 2008
    ..Further understanding of the role these genes play in host specificity and pathogenicity will be important to gain insight into the zoonotic potential of certain EM as well as their mechanisms of virulence...
  15. ncbi request reprint Mycobacterium haemophilum infections of zebrafish (Danio rerio) in research facilities
    Christopher M Whipps
    Department of Microbiology, Center for Fish Disease Research, Oregon State University, Corvallis, OR 97331, USA
    FEMS Microbiol Lett 270:21-6. 2007
    ..Zebrafish are already a well-established laboratory animal model for genetics, toxicology and disease, their susceptibility to M. haemophilum may make them useful for the study of this bacterium in the future...
  16. ncbi request reprint Assessing the accuracy of a polymerase chain reaction test for Ichthyophonus hoferi in Yukon River Chinook salmon Oncorhynchus tshawytscha
    Christopher M Whipps
    Center for Fish Disease Research, Department of Microbiology, 220 Nash, Oregon State University, Corvallis, Oregon 97331 3804, USA
    Dis Aquat Organ 68:141-7. 2006
    ..hoferi. The probability of correctly identifying a negative fish (specificity of the test) was always greater than 94% regardless of the tissue used, infection severity, sampling site or year of collection...
  17. ncbi request reprint First report of three Kudoa species from eastern Australia: Kudoa thyrsites from mahi mahi (Coryphaena hippurus), Kudoa amamiensis and Kudoa minithyrsites n. sp. from sweeper (Pempheris ypsilychnus)
    Christopher M Whipps
    Center for Fish Disease Research, Department of Microbiology, Oregon State University, Corvallis, Oregon 97331 3404, USA
    J Eukaryot Microbiol 50:215-9. 2003
    ..minithyrsites n. sp. on its fish hosts are unknown, both K. thyrsites and K. amamiensis are associated with flesh quality problems in some cultured species and may be potential threats to an expanding aquaculture industry in Australia...
  18. ncbi request reprint Visceral nodular cartilaginous metaplasia in rockfishes (Sebastes spp.) in the eastern North Pacific Ocean
    Jerry R Heidel
    Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Oregon State University, Corvallis 97331 3804, USA
    J Vet Diagn Invest 14:495-7. 2002
    ....
  19. doi request reprint Molecular and morphological analysis of Myxobolus spp. of salmonid fishes with the description of a new Myxobolus species
    Jayde A Ferguson
    Center for Fish Disease Research, Department of Microbiology, Oregon State University, Corvallis, Oregon, USA
    J Parasitol 94:1322-34. 2008
    ..Together, these data show that the Myxobolus sp. from peripheral nerves in the skeletal musculature of coho salmon, rainbow trout, and cutthroat trout is a new species, described herein as Myxobolus fryeri n. sp...
  20. ncbi request reprint Pseudocapillaria tomentosa, a nematode pathogen, and associated neoplasms of zebrafish (Danio rerio) kept in research colonies
    Michael L Kent
    Center for Fish Disease Research, Department of Microbiology, Oregon State University, Corvallis 97331 3804, USA
    Comp Med 52:354-8. 2002
    ..e., intestinal carcinomas and mixed malignant neoplasms). Capillarid nematodes may have intermediate or paratenic hosts. Using a laboratory transmission study, we confirmed that the parasite has a direct life cycle...
  21. ncbi request reprint Quantitative evaluation of macrophage aggregates in brook trout Salvelinus fontinalis and rainbow trout Oncorhynchus mykiss
    Adam R Schwindt
    Department of Microbiology, Center for Fish Disease Research, 220 Nash Hall, Oregon State University, Corvallis, Oregon 97331 3804, USA
    Dis Aquat Organ 68:101-13. 2006
    ....
  22. ncbi request reprint DNA-based identification of a hepatic trematode in an elk calf
    Robert J Bildfell
    Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Magruder Hall, Corvallis, Oregon 97331, USA
    J Wildl Dis 43:762-9. 2007
    ..magna. Phylogenetic analysis showed that it is related to, but is an outlier, to the genus Fasciola. Due to the high mortality rate associated with this disease outbreak, the overall significance of trematodiasis in the herd is unclear...
  23. pmc The state of the art of the zebrafish model for toxicology and toxicologic pathology research--advantages and current limitations
    Jan M Spitsbergen
    Department of Environmental and Molecular Toxicology and Marine Freshwater Biomedical Sciences Center, Oregon State University, Corvallis, Oregon 97333, USA
    Toxicol Pathol 31:62-87. 2003
    ..Therefore, to fully utilize the potential of zebrafish as an animal model for understanding human development, disease, and toxicology we must greatly advance our knowledge on zebrafish diseases and pathology...
  24. doi request reprint Persistence of infection by metacercariae of Apophallus sp., Neascus sp., and Nanophyetus salmincola plus two myxozoans (Myxobolus insidiosus and Myxobolus fryeri) in coho salmon Oncorhynchus kisutch
    Jayde A Ferguson
    Department of Microbiology, Oregon State University, Corvallis, Oregon 97331, USA
    J Parasitol 96:340-7. 2010
    ..declined 43% in the lower main stem fish. However, more than 50% of each species persisted until the end of the study, with smolts still harboring relatively high infections...
  25. ncbi request reprint Environmental stresses and skeletal deformities in fish from the Willamette River, Oregon
    Daniel L Villeneuve
    Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon 97331, USA
    Environ Sci Technol 39:3495-506. 2005
    ..Thus, the weight of evidence suggests that parasitic infection, not chemical contaminants, was the primary cause of skeletal deformities observed in Willamette River fish...
  26. ncbi request reprint Atmospherically deposited PBDEs, pesticides, PCBs, and PAHs in western U.S. National Park fish: concentrations and consumption guidelines
    Luke K Ackerman
    Department of Chemistry, Oregon State University, Corvallis, Oregon 97331, USA
    Environ Sci Technol 42:2334-41. 2008
    ..These results indicate that atmospherically deposited organic contaminants can accumulate in high elevation fish, reaching concentrations relevant to human and wildlife health...
  27. ncbi request reprint Mercury concentrations in salmonids from western U.S. National Parks and relationships with age and macrophage aggregates
    Adam R Schwindt
    Department of Microbiology, Center for Fish Disease Research, 220 Nash Hall, Oregon State University, Corvallis, Oregon 97331, USA
    Environ Sci Technol 42:1365-70. 2008
    ..Our results indicate that mercury is indeed a concern for the U.S. National Parks, from an organismic and potentially an ecosystem perspective...
  28. doi request reprint Description of a new species of Myxobolus (Myxozoa: myxobolidae) based on morphological and molecular data
    Yuanjun Zhao
    The Key Laboratory of Animal Biology of Chongqing, Chongqing Normal University, Chongqing, China
    J Parasitol 94:737-42. 2008
    ..Phylogenetic analyses of the SSU rDNA gene sequence placed this species in a clade composed exclusively of gill parasites, most closely related to Myxobolus longisporus, which also infects the gills of cyprinid fishes in China...
  29. doi request reprint A new species of Henneguya (Myxozoa) in the big-eyed scad (Selar crumenophthalmus) from Hawaii
    Thierry M Work
    U S Geological Survey, National Wildlife Health Center, Honolulu Field Station, 300 Ala Moana Boulevard, Room 5 231, Honolulu, Hawaii 96850, USA
    J Parasitol 94:524-9. 2008
    ..akule n. sp. is most closely related to other Henneguya species infecting the heart of marine fishes based on ribosomal DNA analysis. This is the first documentation of a myxozoan parasite in marine fishes from Hawaii...
  30. ncbi request reprint Ellipsomyxa gobii (Myxozoa: Ceratomyxidae) in the common goby Pomatoschistus microps (Teleostei: Gobiidae) uses Nereis spp. (Annelida: Polychaeta) as invertebrate hosts
    Marianne Køie
    Marine Biological Laboratory, University of Copenhagen, DK 3000 Helsingør, Denmark
    Folia Parasitol (Praha) 51:14-8. 2004
    ..gobii from P. microps. Sequences were identical, which further verifies that both forms belong to the same organism. This is the first myxozoan two-host life cycle in the marine environment...
  31. ncbi request reprint Multivalvulid myxozoans from eastern Australia: three new species of Kudoa from scombrid and labrid fishes of the Great Barrier Reef, Queensland, Australia
    Robert D Adlard
    Biodiversity Program, Queensland Museum, South Brisbane, Australia
    J Parasitol 91:1138-42. 2005
    ..12 (2.04-2.24). All 3 species differ in spore morphology from the 1 previously described myxozoan with 6 polar capsules, Hexacapsula neothunni from yellowfin tuna Neothunnus macropterus, which has since been reassigned to Kudoa...
  32. doi request reprint Replacement of the preoccupied name Davisia Laird 1953 and description of a new myxozoan species (Myxosporea: Sinuolineidae) from Sebastiscus marmoratus (Cuvier, 1829) in the East China Sea
    Yuanjun Zhao
    The Key Laboratory of Animal Biology of Chongqing, Chongqing Normal University, Chongqing 400047, China
    J Parasitol 94:269-79. 2008
    ..there was an indication of a demarcated appendage, but in some mature spores, no clear separation was apparent. Our findings suggest that future revision of this genus is warranted, particularly once DNA sequence data become available...
  33. ncbi request reprint Protozoal and epitheliocystis-like infections in the introduced bluestripe snapper Lutjanus kasmira in Hawaii
    Thierry M Work
    US Geological Survey, National Wildlife Health Center, Hawaii Field Station, 300 Ala Moana Blvd, Room 5 231, Honolulu, Hawaii 96850, USA
    Dis Aquat Organ 57:59-66. 2003
    ....

Research Grants10

  1. CONTROL OF DISEASE IN ZEBRAFISH RESEARCH FACILITIES
    Michael Kent; Fiscal Year: 2007
    ..In addition, the investigators have developed a Web-based fish health manual, and new information generated in the present study will be incorporated into this manual. ..
  2. Control of Diseases in Zebrafish Research Facilities
    MICHAEL LAWRENCE KENT; Fiscal Year: 2010
    ..PCR tests will be made for the virulent strains. Results will be quickly distributed to the zebrafish community through ZFIN, peer reviewed publications, and our web based manual on zebrafish diseases ..