Ovidiu D Iancu

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. pmc Genetic diversity and striatal gene networks: focus on the heterogeneous stock-collaborative cross (HS-CC) mouse
    Ovidiu D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, USA
    BMC Genomics 11:585. 2010
  2. pmc Differential network analysis reveals genetic effects on catalepsy modules
    Ovidiu D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon, USA
    PLoS ONE 8:e58951. 2013
  3. pmc Utilizing RNA-Seq data for de novo coexpression network inference
    Ovidiu D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Bioinformatics 28:1592-7. 2012
  4. doi request reprint Gene networks and haloperidol-induced catalepsy
    O D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, USA
    Genes Brain Behav 11:29-37. 2012
  5. pmc Selection for drinking in the dark alters brain gene coexpression networks
    Ovidiu D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon
    Alcohol Clin Exp Res 37:1295-303. 2013
  6. pmc Detection of expression quantitative trait Loci in complex mouse crosses: impact and alleviation of data quality and complex population substructure
    Ovidiu D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University Portland, OR, USA
    Front Genet 3:157. 2012

Detail Information

Publications6

  1. pmc Genetic diversity and striatal gene networks: focus on the heterogeneous stock-collaborative cross (HS-CC) mouse
    Ovidiu D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, USA
    BMC Genomics 11:585. 2010
    ..Brain (striatum) gene expression data were obtained using the Illumina Mouse WG 6.1 array, and the data sets were interrogated using a weighted gene co-expression network analysis (WGCNA)...
  2. pmc Differential network analysis reveals genetic effects on catalepsy modules
    Ovidiu D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon, USA
    PLoS ONE 8:e58951. 2013
    ..We conclude that, in this case, selective breeding acts at the subnetwork level, with the same modules but not the same transcripts affected across the three selections...
  3. pmc Utilizing RNA-Seq data for de novo coexpression network inference
    Ovidiu D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Bioinformatics 28:1592-7. 2012
    ..Because the capacity of RNA-Seq data for network construction has not been previously evaluated, we constructed a coexpression network using striatal samples, derived its network properties and compared it with microarray-based networks...
  4. doi request reprint Gene networks and haloperidol-induced catalepsy
    O D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, USA
    Genes Brain Behav 11:29-37. 2012
    ..These results suggest that a network-based strategy will help identify the genetic factors associated with haloperidol response...
  5. pmc Selection for drinking in the dark alters brain gene coexpression networks
    Ovidiu D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon
    Alcohol Clin Exp Res 37:1295-303. 2013
    ..Rather than focusing solely on differential expression (DE), we also examine changes in the ways that gene transcripts collectively interact with each other, as revealed by changes in coexpression patterns...
  6. pmc Detection of expression quantitative trait Loci in complex mouse crosses: impact and alleviation of data quality and complex population substructure
    Ovidiu D Iancu
    Department of Behavioral Neuroscience, Oregon Health and Science University Portland, OR, USA
    Front Genet 3:157. 2012
    ..Shared polymorphisms from distinct chromosomes collectively affect expression levels, confounding eQTL detection. We suggest that considering chromosome specific relatedness can result in improved eQTL detection...