Wei Huang

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi Feasibility of using limited-population-based average R10 for pharmacokinetic modeling of osteosarcoma dynamic contrast-enhanced magnetic resonance imaging data
    Wei Huang
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Magn Reson Imaging 27:852-8. 2009
  2. ncbi Discrimination of benign and malignant breast lesions by using shutter-speed dynamic contrast-enhanced MR imaging
    Wei Huang
    W M Keck Foundation High Field MRI Laboratory Advanced Imaging Research Center, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
    Radiology 261:394-403. 2011
  3. ncbi Diagnostic usefulness of water-to-fat ratio and choline concentration in malignant and benign breast lesions and normal breast parenchyma: an in vivo (1) H MRS study
    Sunitha B Thakur
    Departments of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Magn Reson Imaging 33:855-63. 2011
  4. ncbi Dynamic NMR effects in breast cancer dynamic-contrast-enhanced MRI
    Xin Li
    W M Keck Foundation High Field MRI Laboratory Advanced Imaging Research Center, Oregon Health and Science University, Portland, OR 97239, USA
    Proc Natl Acad Sci U S A 105:17937-42. 2008
  5. ncbi Feasibility of using limited-population-based arterial input function for pharmacokinetic modeling of osteosarcoma dynamic contrast-enhanced MRI data
    Ya Wang
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Magn Reson Med 59:1183-9. 2008
  6. ncbi Spectrum separation resolves partial-volume effect of MRSI as demonstrated on brain tumor scans
    Yuzhuo Su
    Department of Biomedical Engineering, The City College of the City University of New York, New York, NY 10031, USA
    NMR Biomed 21:1030-42. 2008
  7. ncbi Enhancing nonmass lesions in the breast: evaluation with proton (1H) MR spectroscopy
    Lia Bartella
    Department of Radiology, Breast Imaging Section H 118, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 245:80-7. 2007
  8. ncbi Magnetic resonance spectroscopy imaging (MRSI) and brain functional magnetic resonance imaging (fMRI) for radiotherapy treatment planning of glioma
    Jenghwa Chang
    Radiation Oncology Department, New York University Langone Medical Center, 556 First Avenue, New York, NY 10016, USA
    Technol Cancer Res Treat 7:349-62. 2008
  9. ncbi The magnetic resonance shutter speed discriminates vascular properties of malignant and benign breast tumors in vivo
    Wei Huang
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 105:17943-8. 2008
  10. ncbi Shutter-speed analysis of contrast reagent bolus-tracking data: Preliminary observations in benign and malignant breast disease
    Xin Li
    Advanced Imaging Research Center, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239, USA
    Magn Reson Med 53:724-9. 2005

Research Grants

  1. Shutter-Speed DCE-MRI Discrimination of Benign and Malignant Breast Disease
    Wei Huang; Fiscal Year: 2009

Collaborators

Detail Information

Publications20

  1. ncbi Feasibility of using limited-population-based average R10 for pharmacokinetic modeling of osteosarcoma dynamic contrast-enhanced magnetic resonance imaging data
    Wei Huang
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Magn Reson Imaging 27:852-8. 2009
    ..61+/-0.19 and 0.55+/-0.14) obtained with the average R(10) approach. The results suggest that it is feasible, as well as practical, to use a limited-population-based average R(10) for pharmacokinetic modeling of osteosarcoma DCE-MRI data...
  2. ncbi Discrimination of benign and malignant breast lesions by using shutter-speed dynamic contrast-enhanced MR imaging
    Wei Huang
    W M Keck Foundation High Field MRI Laboratory Advanced Imaging Research Center, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
    Radiology 261:394-403. 2011
    ..To assess the accuracy of the shutter-speed approach compared with standard approach dynamic contrast material-enhanced magnetic resonance (MR) imaging pharmacokinetic analysis for breast cancer diagnosis...
  3. ncbi Diagnostic usefulness of water-to-fat ratio and choline concentration in malignant and benign breast lesions and normal breast parenchyma: an in vivo (1) H MRS study
    Sunitha B Thakur
    Departments of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Magn Reson Imaging 33:855-63. 2011
    ..Reference standard was histology...
  4. ncbi Dynamic NMR effects in breast cancer dynamic-contrast-enhanced MRI
    Xin Li
    W M Keck Foundation High Field MRI Laboratory Advanced Imaging Research Center, Oregon Health and Science University, Portland, OR 97239, USA
    Proc Natl Acad Sci U S A 105:17937-42. 2008
    ..Thus, if accepted, this analysis would have prevented the 68% of the biopsies that proved benign...
  5. ncbi Feasibility of using limited-population-based arterial input function for pharmacokinetic modeling of osteosarcoma dynamic contrast-enhanced MRI data
    Ya Wang
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Magn Reson Med 59:1183-9. 2008
    ..Further validation with a larger population and multiple regions is desirable...
  6. ncbi Spectrum separation resolves partial-volume effect of MRSI as demonstrated on brain tumor scans
    Yuzhuo Su
    Department of Biomedical Engineering, The City College of the City University of New York, New York, NY 10031, USA
    NMR Biomed 21:1030-42. 2008
    ..These results show that the proposed spectral analysis method can improve the effectiveness of MRSI as a diagnostic tool...
  7. ncbi Enhancing nonmass lesions in the breast: evaluation with proton (1H) MR spectroscopy
    Lia Bartella
    Department of Radiology, Breast Imaging Section H 118, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 245:80-7. 2007
    ....
  8. ncbi Magnetic resonance spectroscopy imaging (MRSI) and brain functional magnetic resonance imaging (fMRI) for radiotherapy treatment planning of glioma
    Jenghwa Chang
    Radiation Oncology Department, New York University Langone Medical Center, 556 First Avenue, New York, NY 10016, USA
    Technol Cancer Res Treat 7:349-62. 2008
    ..An IMRT (intensity-modulated radiotherapy) dose painting plan for this case is also presented using the fused MRSI and fMRI to delineate the clinical target volumes and Broca's area...
  9. ncbi The magnetic resonance shutter speed discriminates vascular properties of malignant and benign breast tumors in vivo
    Wei Huang
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 105:17943-8. 2008
    ..Thus, incorporation of the SSM into the screening protocols would have precluded all 68% of the biopsy/pathology procedures that yielded benign findings. The SM/SSM difference is well understood from molecular first principles...
  10. ncbi Shutter-speed analysis of contrast reagent bolus-tracking data: Preliminary observations in benign and malignant breast disease
    Xin Li
    Advanced Imaging Research Center, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239, USA
    Magn Reson Med 53:724-9. 2005
    ..Furthermore, the shutter-speed model clearly reveals focal "hot spots" of elevated CR perfusion/permeation present in only the malignant tumors...
  11. ncbi A feasible high spatiotemporal resolution breast DCE-MRI protocol for clinical settings
    Luminita A Tudorica
    Diagnostic Radiology, Oregon Health and Science University, Portland, OR, USA
    Magn Reson Imaging 30:1257-67. 2012
    ..The TWIST sequence may be used in clinical settings to acquire high spatiotemporal resolution breast DCE-MRI images for both precise lesion morphology characterization and accurate pharmacokinetic analysis...
  12. ncbi Signal-to-noise ratio, contrast-to-noise ratio and pharmacokinetic modeling considerations in dynamic contrast-enhanced magnetic resonance imaging
    Xin Li
    Advanced Imaging Research Center, Oregon Health and Science University, Mail Code L452, Portland, OR 97239, USA
    Magn Reson Imaging 30:1313-22. 2012
    ..Simulations based on region of interest data further indicate that the effects of intercompartmental water exchange often play an important role in DCE time-course data modeling, especially for protocols optimized for post-CR SNR...
  13. ncbi Proton (1H) MR spectroscopy of the breast
    Lia Bartella
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiographics 27:S241-52. 2007
    ..Although several limitations currently exist that make the technique premature for clinical use, further evaluation with larger, preferably multicenter trials is certainly warranted...
  14. ncbi Magnetic resonance spectroscopy imaging in radiotherapy planning for recurrent glioma
    Ase M Ballangrud
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Med Phys 38:2724-30. 2011
    ..The purpose of this study was to investigate how incorporation of magnetic resonance spectroscopy imaging (MRSI) into radiotherapy planning would increase the target volume for patients with recurrent glioma...
  15. ncbi Feasibility of shutter-speed DCE-MRI for improved prostate cancer detection
    Xin Li
    W M Keck Foundation High Field MRI Laboratory, Advanced Imaging Research Center, Oregon Health and Science University, Portland, Oregon 97239, USA
    Magn Reson Med 69:171-8. 2013
    ..Pathology analyses verify the shutter-speed model (FXR-a) promise for prostate cancer detection. Parametric mapping may further improve pharmacokinetic biomarker performance...
  16. ncbi Proton MR spectroscopy with choline peak as malignancy marker improves positive predictive value for breast cancer diagnosis: preliminary study
    Lia Bartella
    Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Radiology 239:686-92. 2006
    ..To prospectively evaluate the diagnostic performance of magnetic resonance (MR) spectroscopy in patients with suspicious lesions or biopsy-proved cancers at MR imaging by using histologic findings as the reference standard...
  17. ncbi Average arterial input function for quantitative dynamic contrast enhanced magnetic resonance imaging of neck nodal metastases
    Amita Shukla Dave
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    BMC Med Phys 9:4. 2009
    ..Further validation of the Avg-AIF approach with a larger population and in multiple regions is desirable...
  18. ncbi Association between changes in air pollution levels during the Beijing Olympics and biomarkers of inflammation and thrombosis in healthy young adults
    David Q Rich
    Department of Community and Preventive Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA
    JAMA 307:2068-78. 2012
    ..Air pollution is a risk factor for cardiovascular diseases (CVD), but the underlying biological mechanisms are not well understood...
  19. ncbi Image-fusion of MR spectroscopic images for treatment planning of gliomas
    Jenghwa Chang
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Med Phys 33:32-40. 2006
    ..In conclusion, an image-fusion protocol was developed that successfully incorporates MRSI information into the IMRT treatment plan for glioma...
  20. ncbi Cerebral blood volume measurements by rapid contrast infusion and T2*-weighted echo planar MRI
    Alina Tudorica
    Department of Chemistry, SUNY at Stony Brook, Stony Brook, New York, USA
    Magn Reson Med 47:1145-57. 2002
    ..It is possible to measure CBV using dynamic MRI or CT during 30-60-sec contrast infusions. This method may be more sensitive to changes in CBV than traditional AUC methods...

Research Grants1

  1. Shutter-Speed DCE-MRI Discrimination of Benign and Malignant Breast Disease
    Wei Huang; Fiscal Year: 2009
    ..If successful, this SSM method may potentially be incorporated into clinical breast MRI protocols to reduce possibly unnecessary (benign) biopsies, and may be valuable in monitoring cancer treatment. ..