Dana K Howe
Affiliation: Oregon State University
- Muller's Ratchet and compensatory mutation in Caenorhabditis briggsae mitochondrial genome evolutionDana K Howe
Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, 97331, USA
BMC Evol Biol 8:62. 2008..Evidence for Muller's Ratchet and knowledge on its underlying molecular mechanisms, however, are lacking for natural populations...
- Variation in base-substitution mutation in experimental and natural lineages of Caenorhabditis nematodesDee R Denver
Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University, OR, USA
Genome Biol Evol 4:513-22. 2012..Our findings show that base-substitution mutation processes in these closely related animal lineages are mostly stable but differ from natural polymorphism patterns in these two species...
- Selfish little circles: transmission bias and evolution of large deletion-bearing mitochondrial DNA in Caenorhabditis briggsae nematodesKatie A Clark
Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, United States of America
PLoS ONE 7:e41433. 2012..briggsae, offering a powerful new system to study selfish mtDNA dynamics in metazoans...
- Evolution of Caenorhabditis mitochondrial genome pseudogenes and Caenorhabditis briggsae natural isolatesMichael J Raboin
Molecular and Cellular Biology Program, Oregon State University, OR, USA
Mol Biol Evol 27:1087-96. 2010..Our findings provide new insights into the mode and tempo of mitochondrial genome and pseudogene evolution both within and between Caenorhabditis nematode species...
- Selective sweeps and parallel mutation in the adaptive recovery from deleterious mutation in Caenorhabditis elegansDee R Denver
Department of Zoology, Oregon State University, Corvallis, Oregon 97331, USA
Genome Res 20:1663-71. 2010..Our study suggests that recovery-line mutations identified in both coding and noncoding genomic regions might have beneficial effects associated with compensatory epistatic interactions...
- Using mitogenomic and nuclear ribosomal sequence data to investigate the phylogeny of the Xiphinema americanum species complexInga A Zasada
USDA ARS Horticultural Crops Research Laboratory, Corvallis, Oregon, United States of America
PLoS ONE 9:e90035. 2014..The inherent heterogeneity in ITS1 rDNA sequence data and lack of informative sites in 18S rDNA analysis suggests that mtDNA may be more useful in sorting out the taxonomic confusion of the X. americanum species complex. ..
- A genome-wide view of Caenorhabditis elegans base-substitution mutation processesDee R Denver
Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, OR 97331, USA
Proc Natl Acad Sci U S A 106:16310-4. 2009..elegans and many other animal species; this observation challenges the assumption that natural patterns of molecular variation in noncoding regions of the nuclear genome accurately reflect underlying mutation processes...
- High Rate of Large Deletions in Caenorhabditis briggsae Mitochondrial Genome Mutation ProcessesDana K Howe
Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University
Genome Biol Evol 2010:29-38. 2010..elegans as compared with C. briggsae. Our results show that C. briggsae mtDNA is highly susceptible to large deletions and that the mitochondrial mutation process varies between Caenorhabditis nematode species...