Penelope Hogarth

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Huntington's disease: a decade beyond gene discovery
    Penelope Hogarth
    Oregon Health and Science University, Campus Mail OP 32, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA
    Curr Neurol Neurosci Rep 3:279-84. 2003
  2. ncbi request reprint Interrater agreement in the assessment of motor manifestations of Huntington's disease
    Penelope Hogarth
    Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    Mov Disord 20:293-7. 2005
  3. ncbi request reprint Sodium phenylbutyrate in Huntington's disease: a dose-finding study
    Penelope Hogarth
    Department of Neurology, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    Mov Disord 22:1962-4. 2007
  4. ncbi request reprint Pallidal vs subthalamic nucleus deep brain stimulation in Parkinson disease
    Valerie C Anderson
    Department of Neurological Surgery, Oregon Health and Science University, Portland, OR 97201, USA
    Arch Neurol 62:554-60. 2005
  5. pmc Neuro-ophthalmologic and electroretinographic findings in pantothenate kinase-associated neurodegeneration (formerly Hallervorden-Spatz syndrome)
    Robert A Egan
    Casey Eye Institute, Department of Ophthalmology, Oregon Health and Science University, Portland 97201, USA
    Am J Ophthalmol 140:267-74. 2005
  6. ncbi request reprint OFF-off rebound dyskinesia in subthalamic nucleus deep brain stimulation of Parkinson's disease
    Matthew A Brodsky
    Department of Neurology, Oregon Health and Science University, and Parkinson s Disease Research, Education and Clinical Care Center, Portland VA Medical Center, Portland, Oregon, USA
    Mov Disord 21:1487-90. 2006
  7. pmc Effects of a NR2B selective NMDA glutamate antagonist, CP-101,606, on dyskinesia and Parkinsonism
    John G Nutt
    Department of Neurology, Oregon Health and Science University, Portland, Oregon 97201, USA
    Mov Disord 23:1860-6. 2008
  8. ncbi request reprint Multisite randomized trial of deep brain stimulation
    Kenneth Follett
    Arch Neurol 62:1643-4; author reply 1644-5. 2005
  9. pmc Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset
    Nancy S Wexler
    Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 101:3498-503. 2004

Collaborators

  • John G Nutt
  • Matthew A Brodsky
  • Ira Shoulson
  • Steven A Gunzler
  • Michael Krams
  • Susan J Hayflick
  • Karen S Marder
  • R Egan
  • V C Anderson
  • R G Weleber
  • J Michael Andresen
  • Frances Weaver
  • Ali Samii
  • Andrew S Feigin
  • Kenneth Follett
  • Nancy S Wexler
  • William Marks
  • Eugene Lai
  • John Duda
  • Stacy Horn
  • Matthew Stern
  • Katherine Holloway
  • Jeff Bronstein
  • Zane Hollingsworth
  • Sandra Wiktorski
  • Edith Shackell
  • Marcy MacDonald
  • Jack B Penney
  • Gustavo J Rey
  • S Robert Snodgrass
  • Ernesto Bonilla
  • Frederick Marshall
  • Julie Porter
  • James Gusella
  • Leslie M Thompson
  • Stephen R Dlouhy
  • Jose Alvir
  • Diana Rosas
  • Leticia Acosta
  • Kenneth Fischbeck
  • Adam Brickman
  • Steven Hersch
  • Juan Sanchez Ramos
  • Simone A Roberts
  • Theresa Stillings
  • Michael Irizarry
  • Judith Lorimer
  • Graciela Penchaszadeh
  • Marion E Hodes
  • Anne B Young
  • Bernhard Landwehrmeyer
  • Denise Krch
  • Norman Arnheim
  • Fidela Gomez
  • Stacey S Cherny
  • Leon Dure
  • Margot Mieja De Young
  • Christopher J O'Brien
  • P Michael Conneally
  • Jacqueline Gray
  • Americo Negrette
  • Shelley Peery
  • Maria Dolores Martinez-Jaurrieta
  • Jang Ho Cha
  • Maria A Ramos-Arroyo
  • Amarilis Acevedo-Cruz
  • Angela Young
  • Donald S Higgins
  • Denise Brocklebank
  • Carol Moskowitz
  • Jacqueline Bickham
  • Jane Paulsen
  • David E Housman
  • Javier Gayan
  • Lon R Cardon

Detail Information

Publications9

  1. ncbi request reprint Huntington's disease: a decade beyond gene discovery
    Penelope Hogarth
    Oregon Health and Science University, Campus Mail OP 32, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA
    Curr Neurol Neurosci Rep 3:279-84. 2003
    ..The resultant advances in our understanding of the pathogenesis of the disorder are moving us toward rational therapies to slow the progression and delay the onset of the illness...
  2. ncbi request reprint Interrater agreement in the assessment of motor manifestations of Huntington's disease
    Penelope Hogarth
    Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    Mov Disord 20:293-7. 2005
    ..We expect these findings to translate to a similar level of interobserver agreement in the clinical trial setting involving experienced investigators examining live patients...
  3. ncbi request reprint Sodium phenylbutyrate in Huntington's disease: a dose-finding study
    Penelope Hogarth
    Department of Neurology, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    Mov Disord 22:1962-4. 2007
    ..We saw no significant laboratory or electrocardiographic abnormalities. Gene expression changes in blood suggested an inverse dose-response. In conclusion, SPB at 12 to 15 g/day appears to be safe and well-tolerated in human HD...
  4. ncbi request reprint Pallidal vs subthalamic nucleus deep brain stimulation in Parkinson disease
    Valerie C Anderson
    Department of Neurological Surgery, Oregon Health and Science University, Portland, OR 97201, USA
    Arch Neurol 62:554-60. 2005
    ..Although it has been suggested that stimulation of the STN may be superior to stimulation of the GPi, comparative trials are limited...
  5. pmc Neuro-ophthalmologic and electroretinographic findings in pantothenate kinase-associated neurodegeneration (formerly Hallervorden-Spatz syndrome)
    Robert A Egan
    Casey Eye Institute, Department of Ophthalmology, Oregon Health and Science University, Portland 97201, USA
    Am J Ophthalmol 140:267-74. 2005
    ..Since the neuro-ophthalmologic and electroretinographic (ERG) features have never been well delineated, we describe them in 16 patients with PKAN...
  6. ncbi request reprint OFF-off rebound dyskinesia in subthalamic nucleus deep brain stimulation of Parkinson's disease
    Matthew A Brodsky
    Department of Neurology, Oregon Health and Science University, and Parkinson s Disease Research, Education and Clinical Care Center, Portland VA Medical Center, Portland, Oregon, USA
    Mov Disord 21:1487-90. 2006
    ..When the stimulators were turned back on, the dyskinesias soon resolved. This article is a first report of a unique pattern of rebound-type dyskinesia that occurred in the off medication state produced by stopping STN DBS...
  7. pmc Effects of a NR2B selective NMDA glutamate antagonist, CP-101,606, on dyskinesia and Parkinsonism
    John G Nutt
    Department of Neurology, Oregon Health and Science University, Portland, Oregon 97201, USA
    Mov Disord 23:1860-6. 2008
    ..However, future studies will have to determine if the benefits of dyskinesia suppression can be achieved without adverse cognitive effects...
  8. ncbi request reprint Multisite randomized trial of deep brain stimulation
    Kenneth Follett
    Arch Neurol 62:1643-4; author reply 1644-5. 2005
  9. pmc Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset
    Nancy S Wexler
    Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 101:3498-503. 2004
    ..37), shared environment (0.22), and nonshared environment (0.41) variances, confirming that approximately 40% of the variance remaining in onset age is attributable to genes other than the HD gene and 60% is environmental...