Jon Hennebold

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Characterization of the ovarian transcriptome through the use of differential analysis of gene expression methodologies
    Jon D Hennebold
    Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97006, USA
    Hum Reprod Update 10:227-39. 2004
  2. ncbi request reprint Identification and characterization of an ovary-selective isoform of epoxide hydrolase
    Jon D Hennebold
    Division of Reproductive Sciences, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA
    Biol Reprod 72:968-75. 2005
  3. pmc Dynamic changes in gene expression that occur during the period of spontaneous functional regression in the rhesus macaque corpus luteum
    Randy L Bogan
    Oregon Health and Science University, Oregon National Primate Research Center, 505 Northwest 185th Avenue, Beaverton, Oregon 97006
    Endocrinology 150:1521-9. 2009
  4. pmc CDX2 in the formation of the trophectoderm lineage in primate embryos
    Hathaitip Sritanaudomchai
    Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA
    Dev Biol 335:179-87. 2009
  5. pmc Discovery of a novel imprinted gene by transcriptional analysis of parthenogenetic embryonic stem cells
    Hathaitip Sritanaudomchai
    Oregon National Primate Research Center, Beaverton, OR 97006, USA
    Hum Reprod 25:1927-41. 2010
  6. pmc Systematic analysis of protease gene expression in the rhesus macaque ovulatory follicle: metalloproteinase involvement in follicle rupture
    Marina C Peluffo
    Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, Oregon 97006, USA
    Endocrinology 152:3963-74. 2011
  7. ncbi request reprint The identification of novel ovarian proteases through the use of genomic and bioinformatic methodologies
    Kei Miyakoshi
    Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University West Campus, Beaverton, Oregon 97006, USA
    Biol Reprod 75:823-35. 2006
  8. ncbi request reprint The regulated expression of the pregnancy-associated plasma protein-A in the rodent ovary: a proposed role in the development of dominant follicles and of corpora lutea
    Ariel Hourvitz
    Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Utah Health Sciences Center, Huntsman Cancer Institute, 2000 Circle of Hope, Rm 5221, Salt Lake City, UT 84112, USA
    Endocrinology 143:1833-44. 2002
  9. ncbi request reprint Dynamic expression and regulation of the corticotropin-releasing hormone/urocortin-receptor-binding protein system in the primate ovary during the menstrual cycle
    Jing Xu
    Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    J Clin Endocrinol Metab 91:1544-53. 2006
  10. ncbi request reprint Expression and role of the corticotropin-releasing hormone/urocortin-receptor-binding protein system in the primate corpus luteum during the menstrual cycle
    Jing Xu
    Division of Neuuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97006, USA
    Endocrinology 148:5385-95. 2007

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Characterization of the ovarian transcriptome through the use of differential analysis of gene expression methodologies
    Jon D Hennebold
    Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97006, USA
    Hum Reprod Update 10:227-39. 2004
    ..The genes identified through the use of these approaches represent potential targets for designing agents capable of regulating ovarian physiology and thus fertility...
  2. ncbi request reprint Identification and characterization of an ovary-selective isoform of epoxide hydrolase
    Jon D Hennebold
    Division of Reproductive Sciences, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA
    Biol Reprod 72:968-75. 2005
    ..The change in enzyme activity paralleled the combined mRNA expression profiles for both Ephx2A and Ephx2B, thus supporting a role for epoxide metabolism in ovarian function...
  3. pmc Dynamic changes in gene expression that occur during the period of spontaneous functional regression in the rhesus macaque corpus luteum
    Randy L Bogan
    Oregon Health and Science University, Oregon National Primate Research Center, 505 Northwest 185th Avenue, Beaverton, Oregon 97006
    Endocrinology 150:1521-9. 2009
    ..Protein levels were found to parallel mRNA profiles in four of five differentially expressed genes analyzed by Western blot. Thus, this database will facilitate the identification of mechanisms involved in primate luteal regression...
  4. pmc CDX2 in the formation of the trophectoderm lineage in primate embryos
    Hathaitip Sritanaudomchai
    Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA
    Dev Biol 335:179-87. 2009
    ..These results provide evidence that CDX2 plays an essential role in functional TE formation during primate embryonic development...
  5. pmc Discovery of a novel imprinted gene by transcriptional analysis of parthenogenetic embryonic stem cells
    Hathaitip Sritanaudomchai
    Oregon National Primate Research Center, Beaverton, OR 97006, USA
    Hum Reprod 25:1927-41. 2010
    ....
  6. pmc Systematic analysis of protease gene expression in the rhesus macaque ovulatory follicle: metalloproteinase involvement in follicle rupture
    Marina C Peluffo
    Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, Oregon 97006, USA
    Endocrinology 152:3963-74. 2011
    ..These findings demonstrate metalloproteinases are critical for follicle rupture in primates, and blocking their activity would serve as a novel, nonhormonal means to achieve contraception...
  7. ncbi request reprint The identification of novel ovarian proteases through the use of genomic and bioinformatic methodologies
    Kei Miyakoshi
    Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University West Campus, Beaverton, Oregon 97006, USA
    Biol Reprod 75:823-35. 2006
    ..Collectively, these results suggest that the PRSS35 and PRSS23 genes have been conserved as critical ovarian proteases throughout the course of vertebrate evolution...
  8. ncbi request reprint The regulated expression of the pregnancy-associated plasma protein-A in the rodent ovary: a proposed role in the development of dominant follicles and of corpora lutea
    Ariel Hourvitz
    Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Utah Health Sciences Center, Huntsman Cancer Institute, 2000 Circle of Hope, Rm 5221, Salt Lake City, UT 84112, USA
    Endocrinology 143:1833-44. 2002
    ..Accordingly, successful antral follicle development, ovulation, and corpus luteum formation may be contingent on an IGFBP-4-deplete/PAPP-A-replete circumstance, hence resulting in an IGF-I-replete intrafollicular microenvironment...
  9. ncbi request reprint Dynamic expression and regulation of the corticotropin-releasing hormone/urocortin-receptor-binding protein system in the primate ovary during the menstrual cycle
    Jing Xu
    Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA
    J Clin Endocrinol Metab 91:1544-53. 2006
    ..Microarray analysis discovered that mRNA for CRH-binding protein (CRHBP) increased significantly in the primate corpus luteum (CL) after LH withdrawal...
  10. ncbi request reprint Expression and role of the corticotropin-releasing hormone/urocortin-receptor-binding protein system in the primate corpus luteum during the menstrual cycle
    Jing Xu
    Division of Neuuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97006, USA
    Endocrinology 148:5385-95. 2007
    ..The expression pattern and results from antagonist injection are consistent with the hypothesis that CRH/UCN-R activation promotes luteal development and/or structure-function in monkeys during the menstrual cycle...
  11. pmc Systematic determination of differential gene expression in the primate corpus luteum during the luteal phase of the menstrual cycle
    Randy L Bogan
    Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University West Campus, Beaverton, Oregon 97006, USA
    Mol Endocrinol 22:1260-73. 2008
    ..This database will facilitate the identification of many novel or previously underappreciated pathways that regulate the structure and function of the primate CL...
  12. ncbi request reprint Vascular endothelial growth factor (VEGF) production by the monkey corpus luteum during the menstrual cycle: isoform-selective messenger RNA expression in vivo and hypoxia-regulated protein secretion in vitro
    Marta Tesone
    Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon 97006, USA
    Biol Reprod 73:927-34. 2005
    ..05) progesterone, but not VEGF, in the media. These results are consistent with a dynamic, local regulation of VEGF production during the life span of the primate CL that is not directly controlled by LH...
  13. ncbi request reprint H1FOO is coupled to the initiation of oocytic growth
    Mamoru Tanaka
    Department of Obstetrics and Gynecology, Keio University School of Medicine, Shinjuku ku, Tokyo 160 0082, Japan
    Biol Reprod 72:135-42. 2005
    ....
  14. ncbi request reprint The generation and characterization of an ovary-selective cDNA library
    Mamoru Tanaka
    Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
    Mol Cell Endocrinol 202:67-9. 2003
    ..These ovary-selective genes may have significant implications for the understanding of ovarian function in molecular terms and for the development of innovative strategies for the promotion of fertility or its control...

Research Grants7

  1. Epoxyeicosatrienoic Acids in the Ovulatory Follicle
    Jon Hennebold; Fiscal Year: 2006
    ..These studies will provide insight into the action and regulation of EETs in the ovulatory follicle and may yield novel approaches for the regulation of fertility. ..
  2. Prostaglandin Synthesis and Action in the Primate Corpus Luteum
    Jon Hennebold; Fiscal Year: 2009
    ..Such an understanding of PG involvement in the regulation of luteal structure-function may aid in our undestanding of infertility or other disorders associated with luteal dysfunction. ..
  3. Prostaglandin Synthesis and Action in the Primate Corpus Luteum
    Jon D Hennebold; Fiscal Year: 2010
    ..Such an understanding of PG involvement in the regulation of luteal structure-function may aid in our undestanding of infertility or other disorders associated with luteal dysfunction. ..