Research Topics
Species | Jon HenneboldSummaryAffiliation: Oregon Health and Science University Country: USA Publications
Research Grants
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Detail Information
Publications
Characterization of the ovarian transcriptome through the use of differential analysis of gene expression methodologiesJon D Hennebold
Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97006, USA
Hum Reprod Update 10:227-39. 2004..The genes identified through the use of these approaches represent potential targets for designing agents capable of regulating ovarian physiology and thus fertility...- Identification and characterization of an ovary-selective isoform of epoxide hydrolaseJon D Hennebold
Division of Reproductive Sciences, Oregon National Primate Research Center, Beaverton, Oregon 97006, USA
Biol Reprod 72:968-75. 2005..The change in enzyme activity paralleled the combined mRNA expression profiles for both Ephx2A and Ephx2B, thus supporting a role for epoxide metabolism in ovarian function... 
Dynamic changes in gene expression that occur during the period of spontaneous functional regression in the rhesus macaque corpus luteumRandy L Bogan
Oregon Health and Science University, Oregon National Primate Research Center, 505 Northwest 185th Avenue, Beaverton, Oregon 97006
Endocrinology 150:1521-9. 2009..Protein levels were found to parallel mRNA profiles in four of five differentially expressed genes analyzed by Western blot. Thus, this database will facilitate the identification of mechanisms involved in primate luteal regression...- CDX2 in the formation of the trophectoderm lineage in primate embryosHathaitip Sritanaudomchai
Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA
Dev Biol 335:179-87. 2009..These results provide evidence that CDX2 plays an essential role in functional TE formation during primate embryonic development... - Discovery of a novel imprinted gene by transcriptional analysis of parthenogenetic embryonic stem cellsHathaitip Sritanaudomchai
Oregon National Primate Research Center, Beaverton, OR 97006, USA
Hum Reprod 25:1927-41. 2010.... - Systematic analysis of protease gene expression in the rhesus macaque ovulatory follicle: metalloproteinase involvement in follicle ruptureMarina C Peluffo
Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, Oregon 97006, USA
Endocrinology 152:3963-74. 2011..These findings demonstrate metalloproteinases are critical for follicle rupture in primates, and blocking their activity would serve as a novel, nonhormonal means to achieve contraception... - The identification of novel ovarian proteases through the use of genomic and bioinformatic methodologiesKei Miyakoshi
Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University West Campus, Beaverton, Oregon 97006, USA
Biol Reprod 75:823-35. 2006..Collectively, these results suggest that the PRSS35 and PRSS23 genes have been conserved as critical ovarian proteases throughout the course of vertebrate evolution... - The regulated expression of the pregnancy-associated plasma protein-A in the rodent ovary: a proposed role in the development of dominant follicles and of corpora luteaAriel Hourvitz
Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Utah Health Sciences Center, Huntsman Cancer Institute, 2000 Circle of Hope, Rm 5221, Salt Lake City, UT 84112, USA
Endocrinology 143:1833-44. 2002..Accordingly, successful antral follicle development, ovulation, and corpus luteum formation may be contingent on an IGFBP-4-deplete/PAPP-A-replete circumstance, hence resulting in an IGF-I-replete intrafollicular microenvironment... - Dynamic expression and regulation of the corticotropin-releasing hormone/urocortin-receptor-binding protein system in the primate ovary during the menstrual cycleJing Xu
Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA
J Clin Endocrinol Metab 91:1544-53. 2006..Ligand-receptor activity may regulate luteal structure-function, at this point in an unknown manner, in primates... - Expression and role of the corticotropin-releasing hormone/urocortin-receptor-binding protein system in the primate corpus luteum during the menstrual cycleJing Xu
Division of Neuuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97006, USA
Endocrinology 148:5385-95. 2007..The expression pattern and results from antagonist injection are consistent with the hypothesis that CRH/UCN-R activation promotes luteal development and/or structure-function in monkeys during the menstrual cycle... - Systematic determination of differential gene expression in the primate corpus luteum during the luteal phase of the menstrual cycleRandy L Bogan
Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University West Campus, Beaverton, Oregon 97006, USA
Mol Endocrinol 22:1260-73. 2008..This database will facilitate the identification of many novel or previously underappreciated pathways that regulate the structure and function of the primate CL... - Vascular endothelial growth factor (VEGF) production by the monkey corpus luteum during the menstrual cycle: isoform-selective messenger RNA expression in vivo and hypoxia-regulated protein secretion in vitroMarta Tesone
Division of Reproductive Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon 97006, USA
Biol Reprod 73:927-34. 2005..05) progesterone, but not VEGF, in the media. These results are consistent with a dynamic, local regulation of VEGF production during the life span of the primate CL that is not directly controlled by LH... - H1FOO is coupled to the initiation of oocytic growthMamoru Tanaka
Department of Obstetrics and Gynecology, Keio University School of Medicine, Shinjuku ku, Tokyo 160 0082, Japan
Biol Reprod 72:135-42. 2005.... - The generation and characterization of an ovary-selective cDNA libraryMamoru Tanaka
Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
Mol Cell Endocrinol 202:67-9. 2003..These ovary-selective genes may have significant implications for the understanding of ovarian function in molecular terms and for the development of innovative strategies for the promotion of fertility or its control...
Research Grants
- Epoxyeicosatrienoic Acids in the Ovulatory FollicleJon Hennebold; Fiscal Year: 2006..These studies will provide insight into the action and regulation of EETs in the ovulatory follicle and may yield novel approaches for the regulation of fertility. ..
- Prostaglandin Synthesis and Action in the Primate Corpus LuteumJon Hennebold; Fiscal Year: 2009..Such an understanding of PG involvement in the regulation of luteal structure-function may aid in our undestanding of infertility or other disorders associated with luteal dysfunction. ..
- Prostaglandin Synthesis and Action in the Primate Corpus LuteumJon D Hennebold; Fiscal Year: 2010..Such an understanding of PG involvement in the regulation of luteal structure-function may aid in our undestanding of infertility or other disorders associated with luteal dysfunction. ..