M Helfand

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Breast cancer screening: a summary of the evidence for the U.S. Preventive Services Task Force
    Linda L Humphrey
    Oregon Health and Science University and Portland Veterans Affairs Medical Center, Mailcode BICC, 3181 SW Sam Jackson Park Road, Portland, OR 97201 3098, USA
    Ann Intern Med 137:347-60. 2002
  2. ncbi request reprint Incorporating information about cost-effectiveness into evidence-based decision-making: the evidence-based practice center (EPC) model
    Mark Helfand
    Portland VA Medical Center and the Oregon Evidence Based Practice Center, Oregon Health and Sciences University, Portland, Oregon 97239, USA
    Med Care 43:33-43. 2005
  3. pmc Methods for the drug effectiveness review project
    Marian S McDonagh
    Department of Medical Informatics and Clinical Epidemiology and Evidence based Practice Center, School of Medicine, Oregon Health and Science University, Portland, OR, USA
    BMC Med Res Methodol 12:140. 2012
  4. pmc Comparative effectiveness research: challenges for medical journals
    Harold C Sox
    Dartmouth Institute, Dartmouth Medical School, Hanover, New Hampshire, USA
    Trials 11:45. 2010
  5. pmc Clinical outcomes resulting from telemedicine interventions: a systematic review
    W R Hersh
    Division of Medical Informatics and Outcomes Research, Oregon Health and Science University, BICC, 3181 SW Sam Jackson Park Rd, Portland, OR 97201, USA
    BMC Med Inform Decis Mak 1:5. 2001
  6. doi request reprint A CTSA agenda to advance methods for comparative effectiveness research
    Mark Helfand
    Oregon Clinical and Translational Research Center, Oregon Health and Sciences University, and Department of Hospital and Specialty Medicine, The Portland VA Medical Center, Portland, OR, USA
    Clin Transl Sci 4:188-98. 2011
  7. ncbi request reprint Screening for skin cancer
    M Helfand
    Division of Medical Informatics and Outcomes Research, Evidence Based Practice Center, Oregon Health Sciences University, Portland, Oregon 97201 3098, USA
    Am J Prev Med 20:47-58. 2001
  8. ncbi request reprint Using evidence reports: progress and challenges in evidence-based decision making
    Mark Helfand
    Oregon Health and Science University, Portland, USA
    Health Aff (Millwood) 24:123-7. 2005
  9. ncbi request reprint Screening for chlamydial infection
    H D Nelson
    Division of Medical Informatics and Outcomes Research and Evidence based Practice Center, Oregon Health Sciences University, Portland, Oregon 97201 3098, USA
    Am J Prev Med 20:95-107. 2001
  10. ncbi request reprint Screening high-risk populations for thyroid cancer
    K Eden
    Oregon Health Sciences University, Evidence Based Practice Center, Portland, Oregon
    Med Pediatr Oncol 36:583-91. 2001

Detail Information

Publications57

  1. ncbi request reprint Breast cancer screening: a summary of the evidence for the U.S. Preventive Services Task Force
    Linda L Humphrey
    Oregon Health and Science University and Portland Veterans Affairs Medical Center, Mailcode BICC, 3181 SW Sam Jackson Park Road, Portland, OR 97201 3098, USA
    Ann Intern Med 137:347-60. 2002
    ..To synthesize new data on breast cancer screening for the U.S. Preventive Services Task Force...
  2. ncbi request reprint Incorporating information about cost-effectiveness into evidence-based decision-making: the evidence-based practice center (EPC) model
    Mark Helfand
    Portland VA Medical Center and the Oregon Evidence Based Practice Center, Oregon Health and Sciences University, Portland, Oregon 97239, USA
    Med Care 43:33-43. 2005
    ..There is a pressing need for guidance on how to incorporate economic information into evidence-based decision-making. Such guidance should take account of the quality and relevance of economic evaluations...
  3. pmc Methods for the drug effectiveness review project
    Marian S McDonagh
    Department of Medical Informatics and Clinical Epidemiology and Evidence based Practice Center, School of Medicine, Oregon Health and Science University, Portland, OR, USA
    BMC Med Res Methodol 12:140. 2012
    ..In addition, our on-going interactions with the policy-makers that use the reports are described...
  4. pmc Comparative effectiveness research: challenges for medical journals
    Harold C Sox
    Dartmouth Institute, Dartmouth Medical School, Hanover, New Hampshire, USA
    Trials 11:45. 2010
    ....
  5. pmc Clinical outcomes resulting from telemedicine interventions: a systematic review
    W R Hersh
    Division of Medical Informatics and Outcomes Research, Oregon Health and Science University, BICC, 3181 SW Sam Jackson Park Rd, Portland, OR 97201, USA
    BMC Med Inform Decis Mak 1:5. 2001
    ..The objective of this systematic review was to evaluate the efficacy of telemedicine interventions for health outcomes in two classes of application: home-based and office/hospital-based...
  6. doi request reprint A CTSA agenda to advance methods for comparative effectiveness research
    Mark Helfand
    Oregon Clinical and Translational Research Center, Oregon Health and Sciences University, and Department of Hospital and Specialty Medicine, The Portland VA Medical Center, Portland, OR, USA
    Clin Transl Sci 4:188-98. 2011
    ..Insights generated by this work should be of enormous value to PCORI and to the broad range of organizations that will be funding and implementing CER...
  7. ncbi request reprint Screening for skin cancer
    M Helfand
    Division of Medical Informatics and Outcomes Research, Evidence Based Practice Center, Oregon Health Sciences University, Portland, Oregon 97201 3098, USA
    Am J Prev Med 20:47-58. 2001
    ..Current recommendations from professional societies regarding screening for skin cancer vary...
  8. ncbi request reprint Using evidence reports: progress and challenges in evidence-based decision making
    Mark Helfand
    Oregon Health and Science University, Portland, USA
    Health Aff (Millwood) 24:123-7. 2005
    ..GRADE, an international consortium of systematic-review developers and users, is seeking to improve the process of incorporating considerations other than the strength of evidence in making decisions that are evidence based...
  9. ncbi request reprint Screening for chlamydial infection
    H D Nelson
    Division of Medical Informatics and Outcomes Research and Evidence based Practice Center, Oregon Health Sciences University, Portland, Oregon 97201 3098, USA
    Am J Prev Med 20:95-107. 2001
    ..This review updates the literature since the last recommendation of the U.S. Preventive Services Task Force published in 1996...
  10. ncbi request reprint Screening high-risk populations for thyroid cancer
    K Eden
    Oregon Health Sciences University, Evidence Based Practice Center, Portland, Oregon
    Med Pediatr Oncol 36:583-91. 2001
    ..We systematically reviewed evidence on the accuracy of ultrasound and palpation to detect thyroid nodules and of fine needle aspiration (FNA), a confirmatory test, to diagnose thyroid cancer...
  11. ncbi request reprint Rural hospital transfer patterns before and after implementation of a statewide trauma system. OHSU Rural Trauma Research Group
    N C Mann
    Oregon Health Sciences University, School of Medicine, Portland 97201, USA
    Acad Emerg Med 4:764-71. 1997
    ..To evaluate trauma transfer practices in rural Oregon before and after implementation of a statewide trauma system...
  12. ncbi request reprint Patterns of endoscopy use in the United States
    D A Lieberman
    Division of Gastroenterology, Department of Medicine, Oregon Health Sciences University, Portland, Oregon 97207, USA
    Gastroenterology 118:619-24. 2000
    ..The aim of this study was to use a large national endoscopic database to determine why routine endoscopy is performed in diverse practice settings...
  13. ncbi request reprint Adequacy of hospital discharge status as a measure of outcome among injured patients
    R J Mullins
    Department of Surgery, Oregon Health Sciences University, Portland 97201, USA
    JAMA 279:1727-31. 1998
    ..Crude mortality rates at the time of hospital discharge are commonly used to assess the quality of care provided to patients hospitalized following trauma...
  14. ncbi request reprint Effectiveness of Helicobacter pylori therapies in a clinical practice setting
    M B Fennerty
    Department of Medicine, Oregon Health Sciences University, Portland 97201 3098, USA
    Arch Intern Med 159:1562-6. 1999
    ....
  15. ncbi request reprint Hyperbaric oxygen therapy for stroke: a systematic review of the evidence
    Susan Carson
    Oregon Evidence Based Practice Center, Oregon Health and Science University, Department of Medical Informatics and Clinical Epidemiology, Portland, OR 97239, USA
    Clin Rehabil 19:819-33. 2005
    ..To identify the benefits and harms of using hyperbaric oxygen therapy to treat acute or subacute stroke or the chronic effects of a stroke. We aimed to identify any gaps in the evidence to provide guidance for future research...
  16. ncbi request reprint Challenges in systematic reviews that assess treatment harms
    Roger Chou
    Oregon Evidence Based Practice Center, Oregon Health and Science University, and Portland Veterans Affairs Medical Center, Portland, Oregon, USA
    Ann Intern Med 142:1090-9. 2005
    ..This article highlights examples of approaches to methodologic issues associated with performing systematic reviews of harms from 96 Evidence-based Practice Center evidence reports...
  17. ncbi request reprint Methodological shortcomings predicted lower harm estimates in one of two sets of studies of clinical interventions
    Roger Chou
    Oregon Evidence Based Practice Center, Portland, OR, USA
    J Clin Epidemiol 60:18-28. 2007
    ..Little is known, however, about whether perceived methodological shortcomings are associated with lower estimates of harms...
  18. ncbi request reprint Screening for developmental dysplasia of the hip: a systematic literature review for the US Preventive Services Task Force
    Scott A Shipman
    Department of Pediatrics, Oregon Health and Science University, Portland, OR 97239, USA
    Pediatrics 117:e557-76. 2006
    ..Developmental dysplasia of the hip (DDH) represents a spectrum of anatomic abnormalities that can result in permanent disability...
  19. ncbi request reprint Diagnosis, access and outcomes: Update of a systematic review of telemedicine services
    William R Hersh
    Department of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Telemed Telecare 12:S3-31. 2006
    ..Further well-designed research is necessary to understand how best to deploy telemedicine services in health care...
  20. ncbi request reprint Screening for elevated lead levels in childhood and pregnancy: an updated summary of evidence for the US Preventive Services Task Force
    Gary Rischitelli
    Oregon Evidence Based Practice Center, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
    Pediatrics 118:e1867-95. 2006
    ..This review updates the evidence for the benefits and harms of screening and intervention for elevated blood lead in asymptomatic children and pregnant women...
  21. ncbi request reprint Estimating risk of breast cancer in carriers of BRCA1 and BRCA2 mutations: a meta-analytic approach
    Rongwei Fu
    Oregon Evidence Based Practice Center, Oregon Health and Science University, Portland, OR 97239, USA
    Stat Med 26:1775-87. 2007
    ..45 per cent (37.39, 57.72 per cent) and 31.85 per cent (23.72, 41.26 per cent) by 75 years old, respectively. For those with family history, risks of breast cancer conferred by BRCA mutations appear to be higher...
  22. ncbi request reprint Cost-effectiveness of echocardiography to identify intracardiac thrombus among patients with first stroke or transient ischemic attack
    Richard T Meenan
    Oregon Health and Science University Evidence based Practice Center, Portland, USA
    Med Decis Making 27:161-77. 2007
    ..The authors' objective was to evaluate the cost-effectiveness of imaging strategies that use transthoracic (TTE) and transesophageal (TEE) echocardiography for identifying intracardiac thrombus in new stroke patients...
  23. pmc Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis
    Linda L Humphrey
    Oregon Evidence Based Practice Center, Veterans Affairs Medical Center, Portland, OR, USA
    J Gen Intern Med 23:2079-86. 2008
    ..Periodontal disease is common among adults in the US and is a potential source of chronic inflammation. Recent data have suggested an important role for chronic inflammation in the development of coronary heart disease (CHD)...
  24. doi request reprint GRADE guidelines: 3. Rating the quality of evidence
    Howard Balshem
    Oregon Evidence Based Practice Center, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
    J Clin Epidemiol 64:401-6. 2011
    ..GRADE separates the process of assessing quality of evidence from the process of making recommendations. Judgments about the strength of a recommendation depend on more than just the quality of evidence...
  25. doi request reprint Intensive insulin therapy in hospitalized patients: a systematic review
    Devan Kansagara
    Oregon Health and Science University, Portland Veterans Affairs Medical Center, USA
    Ann Intern Med 154:268-82. 2011
    ..The benefits and harms of intensive insulin therapy (IIT) titrated to strict glycemic targets in hospitalized patients remain uncertain...
  26. ncbi request reprint Economic comparison of diagnostic approaches for evaluating osteoporosis in older women
    Dale F Kraemer
    Department of Medical Informatics and Clinical Epidemiology and Evidence based Practice Center, Oregon Health and Science University, Portland, OR 97230, USA
    Osteoporos Int 17:68-76. 2006
    ..Compared to other approaches for diagnosing osteoporosis, sequential use of QUS followed by DXA resulted in fewer women treated and lower total costs...
  27. pmc The evaluation of rectal bleeding in adults. A cost-effectiveness analysis comparing four diagnostic strategies
    Elizabeth Allen
    Portland Veterans Affairs Medical Center, Portland, OR 97207, USA
    J Gen Intern Med 20:81-90. 2005
    ..Though primary care patients commonly present with rectal bleeding, the optimal evaluation strategy remains unknown...
  28. ncbi request reprint Safety of vaginal birth after cesarean: a systematic review
    Jeanne Marie Guise
    Department of Obstetrics and Gynecology, Evidence Based Practice Center, Oregon Health and Science University, UHN 50, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA
    Obstet Gynecol 103:420-9. 2004
    ..To evaluate the benefits and harms of vaginal birth after cesarean compared with repeat cesarean delivery...
  29. ncbi request reprint Screening for postmenopausal osteoporosis: a review of the evidence for the U.S. Preventive Services Task Force
    Heidi D Nelson
    Oregon Health and Science University, and Veterans Affairs Medical Center, Mail Code BICC 504, 3181 SW Sam Jackson Park Road, Portland, OR 97201, USA
    Ann Intern Med 137:529-41. 2002
    ..Although osteoporotic fractures present an enormous health burden, it is not clear whether screening to identify high-risk persons is appropriate...
  30. ncbi request reprint Hyperbaric oxygen therapy for traumatic brain injury: a systematic review of the evidence
    Marian McDonagh
    Department of Medical Informatics and Clinical Epidemiology, Oregon Evidence Based Practice Center, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    Arch Phys Med Rehabil 85:1198-204. 2004
    ..To identify the benefits and harms of hyperbaric oxygen therapy (HBOT) to treat traumatic brain injury (TBI)...
  31. pmc Systematic review of the incidence and consequences of uterine rupture in women with previous caesarean section
    Jeanne Marie Guise
    Department of Obstetrics and Gynecology, Oregon Health and Science University, UHN 50, 3181 SW Sam Jackson Park Road, Portland, OR 97239 3098, USA
    BMJ 329:19-25. 2004
    ..To evaluate the incidence and consequences of uterine rupture in women who have had a delivery by caesarean section...
  32. pmc The effectiveness of primary care-based interventions to promote breastfeeding: systematic evidence review and meta-analysis for the US Preventive Services Task Force
    Jeanne Marie Guise
    Department of Medical Informatics and Clinical Epidemiology and Evidence based Practice Center, Oregon Health and Science University, Portland, Oregon 97239, USA
    Ann Fam Med 1:70-8. 2003
    ..We wanted to systematically review whether primary care-based interventions improve initiation and duration of breastfeeding...
  33. ncbi request reprint A systematic review of the efficacy of telemedicine for making diagnostic and management decisions
    William Hersh
    Division of Medical Informatics and Outcomes Research, Evidence Based Practice Center, Oregon Health and Science University, Portland, Oregon 97201, USA
    J Telemed Telecare 8:197-209. 2002
    ..Despite the widespread use of telemedicine in most major medical specialties, there is strong evidence in only a few of them that the diagnostic and management decisions provided by telemedicine are comparable to face-to-face care...
  34. ncbi request reprint Screening for bacterial vaginosis in pregnancy
    J M Guise
    Department of Obstetrics and Gynecology and Evidence based Practice Center, Oregon Health Sciences University, Portland, Oregon 97201, USA
    Am J Prev Med 20:62-72. 2001
    ..Bacterial vaginosis (BV) is a strong independent risk factor for adverse pregnancy outcomes. BV is found in 9% to 23% of pregnant women. Symptoms include vaginal discharge, pruritus, or malodor, but often women with BV are asymptomatic...
  35. ncbi request reprint Screening for subclinical thyroid dysfunction in nonpregnant adults: a summary of the evidence for the U.S. Preventive Services Task Force
    Mark Helfand
    Oregon Health and Science University, Evidence Based Practice Center, Portland, Oregon 97239, USA
    Ann Intern Med 140:128-41. 2004
    ..Advocates of screening argue that early treatment can prevent serious morbidity in individuals who are found to have laboratory evidence of subclinical thyroid dysfunction...
  36. ncbi request reprint Emerging risk factors for coronary heart disease: a summary of systematic reviews conducted for the U.S. Preventive Services Task Force
    Mark Helfand
    Oregon Evidence Based Practice Center, Veterans Affairs Medical Center, andOregon Health and Science University, Portland, Oregon 97239, USA
    Ann Intern Med 151:496-507. 2009
    ..Traditional risk factors do not explain all of the risk for incident coronary heart disease (CHD) events. Various new or emerging risk factors have the potential to improve global risk assessment for CHD...
  37. ncbi request reprint Screening for hepatitis C virus infection: a review of the evidence for the U.S. Preventive Services Task Force
    Roger Chou
    Oregon Health and Science University and the Veterans Affairs Medical Center, Portland, Oregon 97239, USA
    Ann Intern Med 140:465-79. 2004
    ..Hepatitis C virus (HCV) is the most common bloodborne pathogen in the United States and is an important cause of patient morbidity and mortality, but it is unclear whether screening to identify asymptomatic infected persons is appropriate...
  38. pmc Systematic review of the literature on pain in patients with polytrauma including traumatic brain injury
    Steven K Dobscha
    Portland Center for the Study of Chronic, Comorbid Physical and Mental Disorders, Portland Veterans Affairs Medical Center, Portland, OR 97207, USA
    Pain Med 10:1200-17. 2009
    ....
  39. ncbi request reprint The art and science of incorporating cost effectiveness into evidence-based recommendations for clinical preventive services
    S Saha
    Evidence Based Practice Center, Oregon Health Sciences University, Portland, Oregon, USA
    Am J Prev Med 20:36-43. 2001
    ..While this paper focuses on clinical preventive services (i.e., screening, counseling, immunizations, and chemoprevention), the framework we have developed should be broadly portable to other health care services...
  40. doi request reprint Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis
    Linda L Humphrey
    Department of Medical Informatics and Clinical Epidemiology, Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR 97239 3098, USA
    Mayo Clin Proc 83:1203-12. 2008
    ..To determine whether an elevated homocysteine level is an independent risk factor for the development of coronary heart disease (CHD) to aid the US Preventive Services Task Force in its evaluation of novel risk factors for incident CHD...
  41. doi request reprint AHRQ series paper 2: principles for developing guidance: AHRQ and the effective health-care program
    Mark Helfand
    Oregon Evidence Based Practice Center, Department of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    J Clin Epidemiol 63:484-90. 2010
    ..This article describes some of the fundamental principles that have been developed to guide the work of producing comparative effectiveness reviews (CERs)...
  42. ncbi request reprint C-reactive protein as a risk factor for coronary heart disease: a systematic review and meta-analyses for the U.S. Preventive Services Task Force
    David I Buckley
    Oregon Evidence Based Practice Center, Oregon Health and Science University, Portland, Oregon 97239, USA
    Ann Intern Med 151:483-95. 2009
    ..C-reactive protein (CRP) may help to refine global risk assessment for coronary heart disease (CHD), particularly among persons who are at intermediate risk on the basis of traditional risk factors alone...
  43. doi request reprint Assessment and management of acute pain in adult medical inpatients: a systematic review
    Mark Helfand
    Evidence Based Synthesis Program, Portland Veterans Affairs Medical Center, Portland, OR 97239, USA
    Pain Med 10:1183-99. 2009
    ..To review the literature addressing effective care for acute pain in inpatients on medical wards...
  44. ncbi request reprint Comparative efficacy and safety of long-acting oral opioids for chronic non-cancer pain: a systematic review
    Roger Chou
    Department of Medicine, Oregon Health and Science University, and Oregon Evidence Based Practice Center, Portland, Oregon, USA
    J Pain Symptom Manage 26:1026-48. 2003
    ..A subgroup of three studies on long-acting versus short-acting oxycodone was more homogeneous and provided fair evidence that these formulations are equally effective for pain control...
  45. ncbi request reprint Comparative efficacy and safety of skeletal muscle relaxants for spasticity and musculoskeletal conditions: a systematic review
    Roger Chou
    Department of Medicine, Oregon Health and Science University, Portland, Oregon, USA
    J Pain Symptom Manage 28:140-75. 2004
    ..Dantrolene, and to a lesser degree chlorzoxazone, have been associated with rare serious hepatotoxicity...
  46. pmc Incorporating considerations of resources use into grading recommendations
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:1170-3. 2008
  47. pmc What is "quality of evidence" and why is it important to clinicians?
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:995-8. 2008
  48. doi request reprint Policy rounds: a new series and a call for papers
    Mark Helfand
    Med Decis Making 28:169-71. 2008
  49. ncbi request reprint The cost-effectiveness of screening mammography beyond age 65 years: a systematic review for the U.S. Preventive Services Task Force
    Jeanne Mandelblatt
    Georgetown University Medical Center, Lombardi Cancer Center, Washington, DC 20007, USA
    Ann Intern Med 139:835-42. 2003
    ..The authors performed a review to determine the costs and benefits of mammography screening after age 65 years...
  50. ncbi request reprint Challenges in systematic reviews that evaluate drug efficacy or effectiveness
    P Lina Santaguida
    McMaster University Evidence based Practice Centre, Hamilton, Ontario, Canada
    Ann Intern Med 142:1066-72. 2005
    ....
  51. ncbi request reprint Quality of adverse event assessment in randomized controlled trials and observational studies
    Roger Chou
    Mayo Clin Proc 78:119; author reply 119. 2003
  52. ncbi request reprint Projected cost-effectiveness of statewide universal newborn hearing screening
    Ron Keren
    Department of Medicine, Children s Hospital, Boston, Massachusetts, USA
    Pediatrics 110:855-64. 2002
    ....
  53. pmc Grading quality of evidence and strength of recommendations for diagnostic tests and strategies
    Holger J Schunemann
    Department of Epidemiology, Italian National Cancer Institute Regina Elena, 00144 Rome, Italy
    BMJ 336:1106-10. 2008
  54. ncbi request reprint A look back...and ahead
    Mark Helfand
    Med Decis Making 25:8-10. 2005
  55. pmc GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:924-6. 2008
  56. ncbi request reprint Shared decision making, decision aids, and risk communication
    Mark Helfand
    Med Decis Making 27:516-7. 2007
  57. pmc Going from evidence to recommendations
    Gordon H Guyatt
    CLARITY Research Group, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L8N 3Z5
    BMJ 336:1049-51. 2008