Research Topics
| Patrice K HeldSummaryAffiliation: Oregon Health and Science University Country: USA Publications
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Detail Information
Publications
In vivo correction of murine hereditary tyrosinemia type I by phiC31 integrase-mediated gene deliveryPatrice K Held
Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239, USA
Mol Ther 11:399-408. 2005..The stability of transgene expression, relatively high integration frequency, and significant site specificity that characterize the phiC31 integration system suggest that it may have utility in many gene therapy settings...
In vivo genetic selection of renal proximal tubulesPatrice K Held
Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239, USA
Mol Ther 13:49-58. 2006..These data demonstrate that extensive regeneration of the renal proximal tubule compartment can be achieved through genetic selection of functional cells...
In vivo correction of murine tyrosinemia type I by DNA-mediated transpositionEugenio Montini
Department of Medical and Molecular Genetics, Oregon Health and Sciences University, Portland, Oregon 97239, USA
Mol Ther 6:759-69. 2002..Molecular analysis indicated that high-efficiency DNA-mediated transposition into the mouse genome was strictly dependent on the expression of wild-type transposase...
Disorders of tyrosine catabolismPatrice K Held
Medical Genetics Branch, National Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
Mol Genet Metab 88:103-6. 2006
