Patrice K Held
Affiliation: Oregon Health and Science University
- In vivo correction of murine hereditary tyrosinemia type I by phiC31 integrase-mediated gene deliveryPatrice K Held
Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239, USA
Mol Ther 11:399-408. 2005..The stability of transgene expression, relatively high integration frequency, and significant site specificity that characterize the phiC31 integration system suggest that it may have utility in many gene therapy settings...
- In vivo genetic selection of renal proximal tubulesPatrice K Held
Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239, USA
Mol Ther 13:49-58. 2006..These data demonstrate that extensive regeneration of the renal proximal tubule compartment can be achieved through genetic selection of functional cells...
- In vivo correction of murine tyrosinemia type I by DNA-mediated transpositionEugenio Montini
Department of Medical and Molecular Genetics, Oregon Health and Sciences University, Portland, Oregon 97239, USA
Mol Ther 6:759-69. 2002..Molecular analysis indicated that high-efficiency DNA-mediated transposition into the mouse genome was strictly dependent on the expression of wild-type transposase...
- Disorders of tyrosine catabolismPatrice K Held
Medical Genetics Branch, National Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
Mol Genet Metab 88:103-6. 2006