Research Topics
| Jon M HanifinSummaryAffiliation: Oregon Health and Science University Country: USA Publications
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Detail Information
Publications
Efficacy and safety of tacrolimus ointment treatment for up to 4 years in patients with atopic dermatitisJon M Hanifin
Oregon Health Sciences University, Portland, Oregon 97239, USA
J Am Acad Dermatol 53:S186-94. 2005..This study was designed to evaluate the long-term safety and efficacy of 0.1% tacrolimus ointment in adult and pediatric patients with atopic dermatitis (AD)...
A population-based survey of eczema prevalence in the United StatesJon M Hanifin
Deparment of Dermatology, Oregon Health and Science University, 3303 SW Bond Ave, Portland, OR 97239 4501, USA
Dermatitis 18:82-91. 2007..Prevalence estimates are as high as one-third of the population, depending on the country studied, the age range of the subjects, and the diagnostic criteria used. National estimates of prevalence for the US population are lacking...
Atopic dermatitis: broadening the perspectiveJon M Hanifin
Department of Dermatology, Oregon Health and Science University, Portland, OR 97239, USA
J Am Acad Dermatol 51:S23-4. 2004
Atopiform dermatitis: do we need another confusing name for atopic dermatitis?J M Hanifin
Department of Dermatology OP06, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97201 3098, U S A
Br J Dermatol 147:430-2. 2002
Filaggrin mutations and allergic contact sensitizationJon M Hanifin
Department of Dermatology, Oregon Health and Science University, Center for Health and Healing, Portland, Oregon 97239, USA
J Invest Dermatol 128:1362-4. 2008..Their report provides a fresh perspective on the issues of contact allergy, nickel sensitization, and stratum corneum defects...
The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis. EASI Evaluator GroupJ M Hanifin
Department of Dermatology, Oregon Health Sciences University, Portland 97201 3098, USA
Exp Dermatol 10:11-8. 2001..To test the reliability of the eczema area and severity index (EASI) scoring system by assessing inter- and intra-observer consistency...
Evolving concepts of pathogenesis in atopic dermatitis and other eczemasJon M Hanifin
Department of Dermatology, Oregon Health and Science University, 3303 S W Bond Avenue, Portland, OR 97239 4501, USA
J Invest Dermatol 129:320-2. 2009..These conceptual shifts are nurturing more balanced approaches to understanding eczema and hold the hope for better prevention efforts and more specific molecular targeting for therapy...
Traditional smallpox vaccination with reduced risk of inadvertent contact spread by administration of povidone iodine ointmentErika Hammarlund
Oregon Health and Science University, Vaccine and Gene Therapy Institute, 505 NW 185th Avenue, Beaverton, OR 97006, USA
Vaccine 26:430-9. 2008..Together, this indicates that administration of an antiviral/antimicrobial cream can effectively block virus shedding after traditional smallpox vaccination and reduce the risks of autoinoculation or contact spread...
Prevalence and morphology of hand eczema in patients with atopic dermatitisEric L Simpson
Department of Dermatology, Oregon Health and Science University, Portland, OR, USA
Dermatitis 17:123-7. 2006..During the evaluation of patients presenting with hand eczema, the involvement of dorsal hand surfaces and the volar wrist may suggest atopic dermatitis as a contributing etiologic factor...
Patterns of care and referral in children with atopic dermatitis and concern for food allergyMichele M Thompson
Department of Dermatology, Oregon Health and Science University, Portland, 97239, USA
Dermatol Ther 19:91-6. 2006..Consensus about the role of food allergy between the different providers of AD in children would result in more effective, efficient, and less costly health care...
Is food allergy testing reliable in pediatric atopic dermatitis? A population-based studyLaura E Keck
Department of Dermatology, Oregon Health and Science University, Portland, OR 97239 4501, USA
Chem Immunol Allergy 96:108-12. 2012..We conclude that physician and patient misinterpretation of the relevance and reliability of allergy testing may misdirect proper prevention and therapy of AD...
Antiviral immunity following smallpox virus infection: a case-control studyErika Hammarlund
Vaccine and Gene Therapy Institute, Oregon Health and Science University, 505 NW 185th Ave, Beaverton, OR 97006, USA
J Virol 84:12754-60. 2010....
Does food allergy cause atopic dermatitis? Food challenge testing to dissociate eczematous from immediate reactionsDebra Rowlands
Department of Dermatology, Oregon Health and Science University, Portland, 97201, USA
Dermatol Ther 19:97-103. 2006..Diagnosis of food-induced eczema cannot be made without food challenge testing. Such tests can be practical and useful for dispelling unrealistic assumptions about food allergy causation of atopic dermatitis...
A pilot study of emollient therapy for the primary prevention of atopic dermatitisEric L Simpson
Department of Dermatology, Oregon Health and Science University, Portland, Oregon 97239 4501, USA
J Am Acad Dermatol 63:587-93. 2010..New research reveals the importance of the skin barrier in the development of AD and possibly food allergy and asthma. Correcting skin barrier defects from birth may prevent AD onset or moderate disease severity...
Clinical detection of ichthyosis vulgaris in an atopic dermatitis clinic: implications for allergic respiratory disease and prognosisSam F Bremmer
School of Medicine, MSIII, Oregon Health and Science University, Portland, Oregon 97239, USA
J Am Acad Dermatol 59:72-8. 2008..Recent genetic studies have demonstrated that filaggrin mutations, shown to underlie ichthyosis vulgaris (IV), may also predispose patients with atopic dermatitis to allergic respiratory disease...
Tacrolimus ointment: utilization patterns in children under age 2 yearsTamara Salam Housman
Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
Dermatol Online J 10:2. 2004....
Cell death-induced activation of epidermal growth factor receptor in keratinocytes: implications for restricting epidermal damage in dermatitisMihail S Iordanov
Department of Cell and Developmental Biology, Oregon Health and Science University, Portland, Oregon, USA
J Invest Dermatol 125:134-42. 2005..Our findings demonstrate a potential mechanism for the restriction and repair of spongiotic damage in eczemas...
Effective therapy of childhood atopic dermatitis allays food allergy concernsMichele M Thompson
Department of Dermatology, Oregon Health and Science University, Portland, Oregon 97239-3098, USA
J Am Acad Dermatol 53:S214-9. 2005..We conclude that the effect of successful AD treatment on food allergy and food allergy concern are of interest and worthy of further study...
Smallpox: the basicsMark K Slifka
Vaccine and Gene Therapy Institute, Oregon Health and Science University, 505 NW 185(th) Avenue, Beaverton, OR 97006-3448, USA
Dermatol Clin 22:263-74, vi. 2004..In the age of genetic engineering, these viruses could theoretically be modified to increase their virulence to the levels associated with smallpox itself...
Atopic dermatitisEric L Simpson
Department of Dermatology, Oregon Health and Science University, Portland, Oregon 97239-3098, USA
J Am Acad Dermatol 53:115-28. 2005
Atopic dermatitisEric L Simpson
Department of Dermatology, Oregon Health and Science University, Portland, OR 97239-3098, USA
Med Clin North Am 90:149-67, ix. 2006..This interpretation, based on clinical, epidemiologic, and animal stu-dies, may greatly influence our approach to therapy and prevention of atopic diseases in the coming years...
Cutaneous responses to vaccinia in individuals with previous smallpox vaccinationEric L Simpson
Department of Dermatology, Oregon Health and Science University, Center for Health and Healing CH16D, 3303 SW Bond Ave, Portland, OR 97239 4501, USA
J Am Acad Dermatol 57:442-4. 2007..Vaccinated individuals appear to maintain clinically detectable immunity against vaccinia for at least 20 years after smallpox vaccination...
Considerations for testing irritancy, allergy, and photoreactivity in fragrance safety evaluationsJon M Hanifin
Department of Dermatology, Oregon Health Sciences University, Portland, OR, USA
Am J Contact Dermat 14:100-3. 2003..This paper gives an overview of the RIFM testing and research program, how priorities are established, and how RIFM's safety evaluation process works...
An overview of atopic dermatitisJon M Hanifin
Oregon Health and Science University, Portland, OR, USA
Dermatol Nurs . 2003..Recognizing signs of infection and beginning appropriate treatment for them are important. Instruction on corticosteroid therapy as well as use of topical immunomodulators is crucial to effective acute and long-term management of AD...
Patient and physician perspectives vary on atopic dermatitisRobert O McAlister
National Eczema Association for Science and Education, Portland, Oregon, USA
Cutis 69:461-6. 2002..Although physician and patient perceptions sometimes differed, both groups preferred treatments offering greater effectiveness, fewer adverse effects, and greater applicability to the pediatric population...
Safe treatment of head/neck AD with tacrolimus ointmentS Kang
Department of Dermatology, University of Michigan Medical Center, 1618 Taubman Center, 1500 E Medical Center Drive, Ann Arbor, MI 48109 0314, USA
J Dermatolog Treat 14:86-94. 2003..Atopic dermatitis(AD) with head and neck involvement is common and therapeutically challenging...
Long-term effectiveness and safety of recombinant human interferon gamma therapy for atopic dermatitis despite unchanged serum IgE levelsS R Stevens
Department of Dermatology, Case Western Reserve University and University Hospitals of Cleveland, Ohio 44106 5028, USA
Arch Dermatol 134:799-804. 1998..To assess the long-term effects of recombinant human interferon gamma treatment of atopic dermatitis (AD)...
Novel treatment of chronic severe hand dermatitis with bexarotene gelJ M Hanifin
Department of Dermatology, Oregon Health Sciences University, Portland, OR 97201, USA
Br J Dermatol 150:545-53. 2004..CONCLUSIONS: Bexarotene gel appears to be safe, tolerated by most patients, with useful therapeutic activity in chronic severe hand dermatitis...
Multiple diagnostic techniques identify previously vaccinated individuals with protective immunity against monkeypoxErika Hammarlund
Vaccine and Gene Therapy Institute, Oregon Health and Science University, 505 NW 185th Avenue, Beaverton, Oregon 97006, USA
Nat Med 11:1005-11. 2005....
Tacrolimus ointment for the treatment of atopic dermatitis in adult patients: part I, efficacyJ M Hanifin
Oregon Health Sciences University, Portland, USA
J Am Acad Dermatol 44:S28-38. 2001..Tacrolimus ointment is an effective therapy for the treatment of adult patients with atopic dermatitis on all skin regions including the head and neck...
Intermittent therapy for flare prevention and long-term disease control in stabilized atopic dermatitis: a randomized comparison of 3-times-weekly applications of tacrolimus ointment versus vehicleDebra Breneman
University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
J Am Acad Dermatol 58:990-9. 2008..Intermittent dosing of a topical calcineurin inhibitor for preventing atopic dermatitis (AD) disease relapse in patients with stabilized AD has not been evaluated...
Atopic dermatitis and asthma: parallels in the evolution of treatmentLawrence F Eichenfield
Pediatric and Adolescent Dermatology, Children s Hospital, San Diego, CA 92123, USA
Pediatrics 111:608-16. 2003....
Duration of antiviral immunity after smallpox vaccinationErika Hammarlund
Oregon Health and Science University Vaccine and Gene Therapy Institute, 505 NW 185th Avenue, Beaverton, Oregon 97006, USA
Nat Med 9:1131-7. 2003....
CD30 expression on CD1a+ and CD8+ cells in atopic dermatitis and correlation with disease severityEzogelin Oflazoglu
Translational Biology, Seattle Genetics, Inc, Bothell, WA 98021, USA
Eur J Dermatol 18:41-9. 2008....
Blood concentrations, tolerability and efficacy of pimecrolimus cream 1% in Japanese infants and children with atopic dermatitisLawrence F Eichenfield
Rady Children s Hospital, University of California, San Diego, CA 92123, USA
J Dermatol 34:231-6. 2007..The findings of this study indicate that the use of pimecrolimus cream 1% results in minimal systemic absorption of the active ingredient in pediatric patients of Japanese background with extensive disease...
Consensus conference on pediatric atopic dermatitisLawrence F Eichenfield
American Academy of Dermatology, 930 E. Woodfield Road, Box 4014, Schaumberg, IL 60173-4927, USA
J Am Acad Dermatol 49:1088-95. 2003
Guidelines of care for atopic dermatitis, developed in accordance with the American Academy of Dermatology (AAD)/American Academy of Dermatology Association "Administrative Regulations for Evidence-Based Clinical Practice Guidelines"Jon M Hanifin
American Academy of Dermatology, PO Box 4014, Schaumburg, IL 60168-4014, USA
J Am Acad Dermatol 50:391-404. 2004
